scholarly journals Factors associated with Vitamin D Deficiency in Women: Lesson from Biobank in Qatar

2020 ◽  
Author(s):  
Sharifa Al Thani ◽  
Munass Mohammed ◽  
Hanaa Ahmed
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Vitamin D ◽  
Serum Level ◽  
Vitamin D Deficiency ◽  
P Value ◽  
Milk Consumption ◽  
Factors Associated ◽  
Potential Risk Factors ◽  
Potential Factors

Background: Vitamin D deficiency is affecting the health of humans around the world, and different factors associated with it were studied among different populations. Vitamin D deficiency was studied more often as a predictor to diseases. However, certain factors that could be associated with vitamin D deficiency were not explored among women, specifically in Qatar. Objective: To explore potential risk factors of vitamin D deficiency among women aged 20 to 65, using a sample of records from women volunteers to Qatar Biobank. Hypothesis: The study potential factors (age, BMI, education, income, milk consumption, occupation, pregnancy, physical activity and soft drinks) are associated with vitamin D deficiency. Methodology: We assessed some potential risk factors to vitamin D deficiency using data from Qatar Biobank (n=1000). Women aged 20-65 years old were included in the study. Univariate and multiple logistic regression models were used to model the association between our study potential factors (age, BMI, education, income, milk consumption, occupation, number of children, physical activity, and soft drinks) and being vitamin D deficient. Analysis was conducted using Stata (IC) version 15.0. Results: 654 women out of 1000 had vitamin D deficiency (serum level<20ng/mL), and 346 women that had normal level of vitamin D (serum level>20ng/mL). Vitamin D deficiency was significantly associated with women who drank soda 1-3 per month (p-value= 0.038) and 1-3 per week or more (p-value= 0.021). Also, women who were 41-50 years old (p-value= 0.006), 50 years and older (p-value= 0.000) and women who were students as their occupation (p-value= 0.003). Conclusion: Vitamin D deficiency was common among women in Qatar, as found in the present study. Students, women who drank soda, and younger age (<50) had the highest vitamin D deficiency

scholarly journals Assessment of risk factors associated with vitamin D status among children of an urban and a rural areas of Bangladesh

2020 ◽  
Vol 46 (2) ◽  
pp. 134-141
Author(s):  
Anamika Saha ◽  
Md Salim Shakur ◽  
Runa Laila ◽  
Salomee Shakur ◽  
Md Sohel Shomik ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Hypovitaminosis D ◽  
Urban Children ◽  
Outpatient Department ◽  
P Value ◽  
Rural Children ◽  
Vitamin D Status ◽  
Factors Associated

Background: Vitamin D deficiency is one of the most common micronutrient deficiency in children worldwide, even in Bangladesh. However, to date, the prevalence of vitamin D deficiency among children of different region of Bangladesh is less reported. Objective: This study was conducted to assess vitamin D status of urban and rural Bangladeshi children including the risk factors associated with vitamin D deficiency are also evaluated. Methods: A multi-centre (urban and rural based), cross sectional study was done from July 2016 to June 2017, using serum 25(OH) vitamin D3 as a marker of nutritional vitamin D status. Urban and rural children were taken from Paediatric Outpatient Department, United Hospital Limited. Dhaka and Medical Outpatient Department, Upazila Health Complex, Ghatail, Tangail respectively. Children of 1-10 years age attending OPD with mild undernutrition (<–1 SD z score) and/or clinical features suggestive of vitamin D deficiency were included in the study. Results: A total 150 children were studied with 102 (68.0%) urban and 48 (32.0%) rural children. Hypovitaminosis D (25-OHD <30ng/ml) was found in 75.0% of children. Hypovitaminosis D was found significantly more in urban children (81.0%) compared to rural (62.0%) children (OR=0.382, 95% CI: 0.177-0.822, p value <0.05). Inadequate exposure to sunlight was significantly associated with hypovitaminosis D compared to adequate sun exposure and it was about 2.5 times higher (OR=2.475, 95% CI: 1.139-5.380, p value <0.05). No significant associations of vitamin D deficiency were detected with skin color of children, covering clothes of mother, exclusive breast feeding, limb pain and anthropometric status. Children of higher educated mother (above Secondary School Certificate) (OR=0.412, 95% CI: 0.189-0.900) were more associated with vitamin D deficiency. Conclusion: Vitamin D deficiency (VDD) is prevalent among Bangladeshi children, urban children being more vulnerable to VDD. Adoption of a screening programme for children of all age group and implementation of preventive strategies for VDD through public health policies are strongly recommended. Bangladesh Med Res Counc Bull 2020; 46(2): 134-141

scholarly journals A Clinical Analysis of Vitamin D Status in Patients Before Spinal Surgery

2016 ◽  
Vol 101 (7-8) ◽  
pp. 367-374
Author(s):  
Qingqing Li ◽  
Jianwei Zhang ◽  
Jian Chen ◽  
Jin Fan ◽  
Tao Jiang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Spinal Surgery ◽  
Smoking Habit ◽  
High Body Mass Index ◽  
Clinical Analysis ◽  
Vitamin D Insufficiency ◽  
Vitamin D Status ◽  
Factors Associated

The goal of this paper was to study preoperative concentrations of vitamin D in patients undergoing spinal surgery and analyze relevant risk factors associated with vitamin D deficiency. Vitamin D plays an important role in maintaining normal functions of skeletal muscles, and vitamin D insufficiency or deficiency may affect outcomes of spinal surgery patients. A retrospective analysis was conducted on 503 patients undergoing spinal surgery in the First Affiliated Hospital with Nanjing Medical University from September 2012 to October 2013. Preoperative concentrations of serum 25-hydroxyvitamin D [25(OH)D] were measured. Normal vitamin D was defined as a serum 25(OH)D level ≥ 32 ng/mL, vitamin D insufficiency as ≥20 and &lt;32 ng/mL, and vitamin D deficiency as &lt;20 ng/mL. Relevant risk factors associated with vitamin D insufficiency and deficiency were analyzed. In 503 spinal surgery patients, rate of vitamin D deficiency and insufficiency was 71.4% and 23.9%. Rate of vitamin D deficiency in female patients was significantly higher than that in male (P &lt; 0.001). Rate of vitamin D deficiency in patients with high body mass index (P = 0.009) or patients with smoking habit (P &lt; 0.001) was much higher than other patients. Multivariate analysis demonstrated that female (P &lt; 0.001), smoking (P = 0.005), and winter (P = 0.001) were potential risk factors for vitamin D deficiency. Screening preoperative vitamin D status and relevant treatment should be reinforced in spine surgery patients.

scholarly journals Prevalence and Determinants of QuantiFERON-Diagnosed Tuberculosis Infection in 9810 Mongolian Schoolchildren

2018 ◽  
Vol 69 (5) ◽  
pp. 813-819 ◽  
Author(s):  
Davaasambuu Ganmaa ◽  
Polyna Khudyakov ◽  
Uyanga Buyanjargal ◽  
Badamtsetseg Jargalsaikhan ◽  
Delgerekh Baigal ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Environmental Tobacco Smoke ◽  
Tobacco Smoke ◽  
Modifiable Risk Factors ◽  
Cross Sectional ◽  
Hydroxyvitamin D ◽  
Potential Risk Factors ◽  
Independent Association

Abstract Background There is controversy regarding the potential influence of vitamin D deficiency, exposure to environmental tobacco smoke, BCG vaccination, season, and body habitus on susceptibility to Mycobacterium tuberculosis (MTB) infection. Methods We conducted a cross-sectional analysis to identify determinants of a positive QuantiFERON-TB Gold (QFT) assay result in children aged 6–13 years attending 18 schools in Ulaanbaatar, Mongolia. Data relating to potential risk factors for MTB infection were collected by questionnaire, physical examination, and determination of serum 25-hydroxyvitamin D (25[OH]D) concentrations. Risk ratios (RRs) were calculated with adjustment for potential confounders, and population attributable fractions (PAFs) were calculated for modifiable risk factors identified. Results Nine hundred forty-six of 9810 (9.6%) participants had a positive QFT result. QFT positivity was independently associated with household exposure to pulmonary tuberculosis (adjusted RR [aRR], 4.75 [95% confidence interval {CI}, 4.13–5.46, P < .001]; PAF, 13.1% [95% CI, 11.1%–15.0%]), vitamin D deficiency (aRR, 1.23 [95% CI, 1.08–1.40], P = .002; PAF, 5.7% [95% CI, 1.9%–9.3%]), exposure to environmental tobacco smoke (1 indoor smoker, aRR, 1.19 [95% CI, 1.04–1.35]; ≥2 indoor smokers, aRR, 1.30 [95% CI, 1.02–1.64]; P for trend = .006; PAF, 7.2% [95% CI, 2.2%–12.0%]), and increasing age (aRR per additional year, 1.14 [95% CI, 1.10–1.19], P < .001). No statistically significant independent association was seen for presence of a BCG scar, season of sampling, or body mass index. Conclusions Vitamin D deficiency and exposure to environmental tobacco smoke are potentially modifiable risk factors for MTB infection.

High Prevalence of Vitamin D Deficiency and Associated Risk Factors among Employed Women in a Sunny Industrial City

2015 ◽  
Vol 85 (3-4) ◽  
pp. 119-128 ◽  
Author(s):  
Tahereh Hassannia ◽  
Ehsan GhaznaviRad ◽  
Rosita Vakili ◽  
Sohaila Taheri ◽  
Seyed Abdolrahim Rezaee
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Serum Level ◽  
Vitamin D Deficiency ◽  
Muscle Pain ◽  
Serum Vitamin ◽  
Industrial City ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Employed Women

Abstract. Background: Vitamin D deficiency is a public health concern associated with the pathogenesis of several chronic disorders, particularly in women. Aim: To evaluate serum vitamin D levels and its deficiency and risk factors among employed women in a sunny industrial city. Methods: In this cross-sectional study, serum vitamin D levels, biochemical and hematological factors were assessed in 382 healthy employed women. Demographic information was collected using a standard questionnaire and data was analyzed by SPSS software. Results: The mean vitamin D serum level was 22 ± 19.8 ng/ml. Prevalence of vitamin D deficiency and insufficiency were 62 % and 12.94 %, respectively. Deficiency was more common among younger subjects (< 29 years old). 23.5 % of subjects had normal and 1.35 % had toxic levels of vitamin D. Maximum serum level was observed in part-time job employees (33 ng/ml), and the lowest in Media and Culture Organizations (15 ng/ml).Vitamin D deficiency was associated with the lack of sunlight exposure at home, and taking anti-hypertensive medications. The common symptoms in deficiency condition were history of hyperlipidemia, depression, weakness, fatigue, finger tingling, leg cramps, and body and muscle pain. Moreover, LDL-cholesterol serum levels were significantly higher in the vitamin D deficiency group, with a prevalence of 40 %. Conclusion: The symptoms of vitamin D deficiency including depression, weakness, fatigue, tingling, leg cramps and body and muscle pain have been observed in more than 90 % after recruitment and treatment. Therefore, for improving the health and productivity of employees, a routine monitoring system for vitamin D and the other factors should be put in place.

Prevalence and potential risk factors associated with methicillin resistant Staphylococcus aureus infection in Dairy farms

2020 ◽  
Vol 21 (2) ◽  
pp. 39-47
Author(s):  
Mohamed El-Fateh ◽  
Adel El-Gohary ◽  
Mona Elsayed ◽  
Fatma El-Gohary
Keyword(s):  
Risk Factors ◽  
Staphylococcus Aureus ◽  
Environmental Samples ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Potential Risk Factors

Objective: A cross sectional study was conducted between June 2017 and August 2018 in around Dakahlia governorate to identify Methicillin resistant Staphylococcus aureus (MRSA) and to determine risk factors associated with the occurrence of mastitis in dairy cows. Design: Cross sectional study Animals and samples: 130 dairy cattle (744 samples) and 181 environmental samples (36 bedding, 37 bulk tank milk BTM, 27 feed troughs, 27 water troughs, 27 milk linear and 27 worker’s nasal swabs), with a total of 925 samples were studied. Procedures: Three hundred and seventy-two quarters were examined to detect clinical and subclinical mastitis by physical examinations and California mastitis test. In addition, bacteriological isolation and identification of Staphylococcus aureus and MRSA were carried on the above milk samples of above mentioned quarters, teat swabs and environmental samples. Results: The overall prevalence of Staphylococcus aureus and MRSA was 59.4 and 22.4, respectively. The MRSA were more prevalent in mastitic quarter (X2 = 31.146, P-value = 0.000), Holstein Friesian breed (P-value = 0.021), Old aged dairy cattle (>8 years) (P-value = 0.000), Multiparous cows (P-value = 0.000), large herd size (>=2000) (P-value = 0.000). Conclusion and clinical relevance: The present result indicates that MRSA is a major cause of mastitis in dairy farms at northern Egypt, where one of the key elements for controlling its spreading depends mainly on determining its potential risk factors responsible for its existence.

scholarly journals VITAMIN-D DEFICIENCY DURING PREGNANCY;

2012 ◽  
Vol 20 (01) ◽  
pp. 078-081
Author(s):  
SUMBUL SOHAIL ◽  
SHAISTA RASHID
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Vitamin D3 ◽  
Chronic Renal Disease ◽  
Sun Exposure ◽  
Cross Sectional ◽  
Factors Associated ◽  
Low Level ◽  
Vitamin D Supplement

Objective: To find out the frequency of vitamin-D deficiency during pregnancy by using Serum 25 hydroxy vitamin-D3 leveland to evaluate the risk factors associated with low level of vitamin-D. Study Design: Cross Sectional Study. Setting: Gynae and obstetricunit II in Abbasi Shaheed Hospital Karachi. Period: February 2011 to July 2011. Material and methods: Design: All patients with historyof chronic renal disease, liver disorder, PIH, GDM, twin gestation, anti tuberculous treatment and antiepileptic treatment with excluded.Data was collected by predesigned proforma through personal interview. Result: This study showed 49 cases (98%) of primigravidawere vitamin-D deficiency. The highest low level was in 15-25 years of age. The mean concentration of 25bOH vitamin-D 3 was 10.30ng/ml.60 % of women had severe vitamin-D deficiency with level of 25 OH vitamin-D3 was lessthan 10ng/ml. Risk factors associated withlow level of vitamin-D3 included dietary deficiency , lack of sun exposure and practicing veil. Conclusions: Pregnant women includingprimigravida in Pakistan are at risk of vitamin-D deficiency. 25 (OH) assay should be used as an aid in assessment of vitamin-D deficiencyduring pregnancy so that proper correction can be achieved. Women who are deficient in vitamin-D should be counseled regardingmaternal and neonatal risk, a balanced diet ,limited sun exposure and compliance of vitamin-D supplement to ensure normal maternal andfetal outcome. Every women should provided by vitamin-D supplement prior to pregnancy.

scholarly journals Vitamin D status among infants attending Reproductive and Child Health Centre in Arusha, Tanzania; A cross-sectional study 

2021 ◽  
Author(s):  
Victor Zablon Urio ◽  
Kasirye Phillip ◽  
Victor Musiime ◽  
Theresa Piloya ◽  
Stephen Swanson
Keyword(s):  
Vitamin D ◽  
Child Health ◽  
Vitamin D Deficiency ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Reproductive And Child Health ◽  
And Child Health

Abstract Background: Globally there is a high burden of low serum vitamin D levels, with children being more at risk, due to low intake in breastmilk, few available foods and inadequate cutaneous synthesis of vitamin D. Even in countries with abundant sunshine, Vitamin D deficiency (VDD) remains a problem. The classical clinical effect of severe vitamin D deficiency is rickets. VDD is common in developing countries and may affect developmental outcomes of children. This study aimed to determine the prevalence and factors associated with vitamin D deficiency among infants attending the Reproductive and Child Health Clinic (RCH), in Arusha, Tanzania.Methods: This was a cross-sectional study of infants aged 6 weeks to 12 months attending RCH clinic at Arusha Lutheran Medical Centre (ALMC). We enrolled 304 infants from November 2018 to January 2019 after consent. A pre-coded questionnaire was used to collect data on sociodemographic characteristics of the infants. Physical examination was done for anthropometric measures and signs of rickets. Serum was drawn for assessment of 25-hydroxyvitamin D (25(OH) D),calcium, phosphorus, alkaline phosphate was assessed. Vitamin D deficiency was defined as 25(OH)D less than 20ng/ml. Multivariate analysis was done to determine factors associated with VDD. Statistical analysis was performed using STATA 14 version. P- value < 0.05 was significant. Results: A total of 67/ 304 infants had vitamin D deficiency. Another 50(16.5%) were found to have insufficiency level of vitamin D. Only 187(61.5%) had adequate vitamin D. Signs of rickets were observed in 11(3.6%) and hypocalcemia in 33(10.9%) infants. Factors independently associated with VDD include age < 6 months Adjusted Odds Ratio (AOR) 1.56 (95% CI 1.19-4.0) p value < 0.026, presence of signs of rickets and hypocalcemia p value <0.001 and <0.002 respectively. Conclusion and Recommendation: A high prevalence of VDD (22%) was observed among infants attending RCH clinic in Arusha Tanzania. Age <6 months and the presence of the clinical sign of rickets were associated with VDD. Clinicians should actively assess for VDD and vitamin D supplementation with special emphasis infants <6 months should be implemented.

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