The role of conservative treatment in morbid obesity (minireview)

2021 ◽  
Vol 76 (76) ◽  
pp. 45-51
Author(s):  
S.Sh. Asadova ◽  
Sh. N. Gasimov
Keyword(s):  
Morbid Obesity ◽  
Conservative Treatment

Inter-Tissue and Intra-Tissue Co-Expression Networks in Human Metabolism: Morphological Evaluation of the Link Between Transcription Factors ERβ and NFAT in Morbid Obesity

2020 ◽  
Vol 17 (1) ◽  
pp. 63-80
Author(s):  
Athina Chasapi ◽  
Kostas Balampanis ◽  
Eleni Kourea ◽  
Fotios Kalfaretzos ◽  
Vaia Lambadiari ◽  
...  
Keyword(s):  
Morbid Obesity ◽  
Adipose Tissue ◽  
Clinicopathological Parameters ◽  
Morbidly Obese ◽  
Human Metabolism ◽  
Activated T Cells ◽  
Alcoholic Fatty Liver ◽  
Morphological Evaluation ◽  
Underlying Mechanisms

Background: Estrogen receptor β (ERβ) plays an important role in human metabolism and some of its metabolic actions are mediated by a positive “cross-talk” with Nuclear Factor of Activated T cells (NFAT) and the key metabolic transcriptional coregulator Transcriptional Intermediary Factor 2 (TIF2). Introduction: Our study is an “in situ” morphological evaluation of the communication between ERβ, NFAT and TIF2 in morbid obesity. Potential correlations with clinicopathological parameters and with the presence of diabetes and non-alcoholic fatty liver disease (NAFLD) were also explored. The aim of the present study was to determine the role of ERβ and NFAT in the underlying pathophysiology of obesity and related comorbidities. We have investigated the expression of specific proteins using immunochemistry methodologies. Methods: Our population consists of 50 morbidly obese patients undergoing planned bariatric surgery, during which biopsies were taken from visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), skeletal muscle (SM), extramyocellular adipose tissue (EMAT) and liver and the differential protein expression was evaluated by immunohistochemistry. Results: We demonstrated an extensive intra- and inter-tissue co-expression network, which confirms the tissue-specific and integral role of each one of the investigated proteins in morbid obesity. Moreover, a beneficial role of ERβ and NFATc1 against NAFLD is implicated, whereas the distinct roles of TIF2 still remain an enigma. Conclusions: We believe that our findings will shed light on the complex underlying mechanisms and that the investigated biomarkers could represent future targets for the prevention and therapy of obesity and its comorbidities.

The Role of Conservative Treatment in Blunt Ureteral Trauma: Case Report

1981 ◽  
Vol 146 (7) ◽  
pp. 516-520
Author(s):  
Sung-Won Kim ◽  
Edwin C. Tan ◽  
Elliot L. Cohen
Keyword(s):  
Case Report ◽  
Conservative Treatment ◽  
Ureteral Trauma ◽  
Trauma Case

scholarly journals The Role of Conservative Treatment in Idiopathic Granulomatous Mastitis

2005 ◽  
Vol 11 (6) ◽  
pp. 454-456 ◽  
Author(s):  
Eric C. H. Lai ◽  
Wing Cheong Chan ◽  
Tony K. F. Ma ◽  
Alice P. Y. Tang ◽  
Cycles S. P. Poon ◽  
...  
Keyword(s):  
Conservative Treatment ◽  
Granulomatous Mastitis ◽  
Idiopathic Granulomatous Mastitis

scholarly journals The Role of Morbid Obesity in the Promotion of Metabolic Disruptions and Non-Alcoholic Steatohepatitis by Helicobacter Pylori

PLoS ONE ◽  
2016 ◽  
Vol 11 (11) ◽  
pp. e0166741 ◽  
Author(s):  
Albert Lecube ◽  
Silvia Valladares ◽  
Carolina López-Cano ◽  
Liliana Gutiérrez ◽  
Andreea Ciudin ◽  
...  
Keyword(s):  
Morbid Obesity ◽  
Helicobacter Pylori ◽  
Alcoholic Steatohepatitis

Morbid obesity and hypertension: The role of peri-renal fat

2018 ◽  
Vol 275 ◽  
pp. e77
Author(s):  
M.A. Ricci ◽  
M. Scavizzi ◽  
S. Ministrini ◽  
E. Nulli Migliola ◽  
S. De Vuono ◽  
...  
Keyword(s):  
Morbid Obesity

scholarly journals Efficiency Biliopancreatic bypass surgery in bulimia nervosa

2008 ◽  
Vol 5 (2) ◽  
pp. 27-31
Author(s):  
Yu I Yashkov ◽  
D K Bekuzarov ◽  
A V Nikol'skiy
Keyword(s):  
Morbid Obesity ◽  
Surgical Treatment ◽  
Bulimia Nervosa ◽  
Bypass Surgery ◽  
Clinical Signs ◽  
Small Sample ◽  
Choice Of Treatment ◽  
Treatment Of Obesity ◽  
Uncontrolled Eating

A clinical significance in the treatment of bulimia nervosa patients with morbid obesity had already been raised [10, 13], but we did not find publications on the effectiveness of bariatric surgery in these cases. There is also information about the possibility of applying the operation bilio-pancreatic bypass, effective in patients with morbid obesity with uncontrolled eating behavior for the treatment of patients with anorexia BILIM not suffering from morbid obesity. In this article the data of clinical observation of a small sample of patients. As a result, the treatment of these patients found that severe nervous BILIM can be seen as a latent form of morbid obesity. The choice of treatment should depend not only on the initial body weight of the patient, but also on the severity of the nervous BILIM. Unsuccessful attempts at organized-balanced, conservative treatment of patients with severe bulimia nervosa may be considered a variant of surgical treatment, while bilio-pancreatic bypass surgery is considered as the most preferred operation, compared with the installation of the gastric balloon and others. All candidates for surgical treatment of obesity must identify clinical signs of bulimia nervosa, as this may influence the choice of method of operation. Further study of the role of hyperinsulinemia, secretion of ghrelin, leptin, intestinal peptide may contribute to the elucidation of the true causes of bulimia nervosa, probably has a similar origin with morbid obesity.

scholarly journals ENT trauma in children: causes, frequency and characteristics in different periods of childhood

2020 ◽  
Vol 19 (6) ◽  
pp. 94-101
Author(s):  
E. Yu. Radtsig ◽  
◽  
M. M. Evsikova ◽  
M. A. Varavina ◽  
◽  
...  
Keyword(s):  
Conservative Treatment ◽  
Soft Tissues ◽  
Traumatic Events ◽  
Frequency Of Occurrence ◽  
External Nose ◽  
Post Traumatic

Numerous injuries (and their treatment) have been encountered since the very beginning of the development of human civilization and remain one of the most significant problems in our time, since the frequency of injuries in general (and of ENT organs in particular) does not tend to decrease either in children or adults. ENT injuries are in fourth place in terms of emergency appeal rates. The most common injury to the maxillofacial area is a fracture of the skeleton of the nose. The article presents data on the frequency of occurrence of this pathology and describes the features of the causes that caused it in different periods of childhood, presents an algorithm for managing patients. The role of homeopathic arnica-containing remedies (Arnigel®) in the conservative treatment of reactive post-traumatic events from the soft tissues of the external nose is shown.

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