scholarly journals SERUM MAGNESIUM LEVEL

2010 ◽  
Vol 17 (02) ◽  
pp. 279-285
Author(s):  
SADIA ZAFAR ◽  
HINA AYESHA ◽  
ASGHAR BUTT ◽  
Bushra Abdul Malik

Objectives: To evaluate serum magnesium level in children with 3rd degree malnutrition and to compare these values with healthy children. Study Design: Cross sectional comparative study. Setting and Duration: Pediatric Department of Allied Hospital Faisalabad from Oct. 2003 to Nov. 2004. Subjects: Cases: 60 children of age six month to five year having weight < 60% of that for age. Control: 60 healthy children of age six month to five year having weight > 80% of that for age. Methods: Both cases & controls were selected from indoor & outdoor through simple random sampling. Detailed history & examination was done and S/Mg level were measured by atomic absorption spectrophotometer. Data was analyzed with the help of SPSS by applying T test and was presented by frequency tables. Results: The cases showed decreased S/Mg level (1.11+/- 0.24 mg/dl) as compared to controls (2.01+/- 0.78mg/dl).S/Mg levels were also decreased in cases with height < 80 % of that for age (0.98+/-0.5mg/dl) as compared to controls having height > 90 % of that for age. S/Mg levels were markedly low in cases who had low albumin level (0.98+/- 0.05 mg/dl) and those children who presented with persistent diarrhea (0.96+/-0.12mg/dl) Conclusion: S/Mg levels were decreased in children with PEM as compared to those with age and sex matched control. This decrease in S/Mglevels was marked in those cases who had decrease serum albumin level and persistent diarrhea.

2021 ◽  
pp. 33-35
Author(s):  
Manish Kumar ◽  
Syed Yousuf Faisal ◽  
Sudhir Chandra Jha ◽  
Debarshi Jana

Introduction: Both diabetes mellitus and hypertension are aspects of metabolic syndrome. Objectives: The aim of this study was to determine the relationship between serum magnesium level with resistant hyperlipidemia in a group of diabetic and hypertensive patients. Patients And Methods: The present cross- sectional study was carried out on 90 hypertensive and diabetic patients in Medicine Department of DMCH, Laheriasarai, Bihar, (45 hypertensive and 45 diabetic patients). Included patients had high triglyceride levels despite 8 weeks of treatment with lipid-lowering agents. Results: There was an inverse signicant relationship between serum magnesium and triglyceride levels in diabetic patients (P=0.002, r=-0.458), however, this correlation was not signicant in hypertensive patients (P=0.754, r=0.048). Conclusion: This study showed, serum magnesium may affect triglycerides levels in diabetic patients, however, our nding requires further investigation with larger population


2018 ◽  
Vol 10 (1) ◽  
pp. 10-15
Author(s):  
HL Roy ◽  
S Nargis ◽  
SH Mahmud ◽  
NWB Jahan ◽  
MS Hossain ◽  
...  

Preeclampsia is the most common medical complication of pregnancy associated with increased maternal and infant mortality and morbidity. Reduced serum magnesium level is found to be associated with elevated blood pressure in preeclampsia. The purpose of this cross-sectional study is to evaluate the serum magnesium level in preeclamptic women. For this study 50 preeclamptic patients, with age range 20 to 40 years having gestational age range from 20 to 40 weeks and 50 age and gestational age matched normotensive pregnant women having no proteinuria were enrolled. Serum magnesium was measured by colorimetric method. The mean(±SD) age and mean(±SD) gestational age of preeclampsia was not significantly different from those of normotensive pregnant women (p=0.203 and p=0.251 respectively). The mean(±SD) body mass index of the preeclamptic patients was significantly higher compared to that of normotensive pregnant women (p<0.001). The mean(±SD) serum magnesium level was 3.37±2.05 mg/dl in preeclamptic group and 2.87±1.38 mg/dl in normal pregnant women; the level did not differ significantly between the subject of preeclampsia and normal pregnant women (p=0.153). Findings of this study suggest that serum magnesium has no association with preeclampsia.Bangladesh J Med Biochem 2017; 10(1): 10-15


2019 ◽  
Vol 9 (1) ◽  
pp. e07-e07
Author(s):  
Pardis Kaveh ◽  
Afsaneh Malekpour Tehrani ◽  
Saeid Mardani

Introduction: Both diabetes mellitus and hypertension are aspects of metabolic syndrome. Objectives: The aim of this study was to determine the relationship between serum magnesium level with resistant hyperlipidemia in a group of diabetic and hypertensive patients. Patients and Methods: The present cross-sectional study was carried out on 90 hypertensive and diabetic patients who referred to outpatient university clinic in Shahrekord (45 hypertensive and 45 diabetic patients). Included patients had high triglyceride levels despite 8 weeks of treatment with lipid-lowering agents. Results: There was an inverse significant relationship between serum magnesium and triglyceride levels in diabetic patients (P=0.002, r=-0.458), however, this correlation was not significant in hypertensive patients (P=0.754, r=0.048). Conclusion: This study showed, serum magnesium may affect triglycerides levels in diabetic patients, however, our finding requires further investigation with larger population.


2018 ◽  
Vol 25 (04) ◽  
pp. 562-567
Author(s):  
Sunela Ropeta ◽  
Habiba Sharaf Ali

Background: Spontaneous preterm labor that is labor before 37 weeks ofgestation is the main cause of preterm delivery. With increasing gestation the level of Serummagnesium levels decreases. Magnesium inhibits uterine contractions by antagonizing calcium.Hypomagnesaemia also causes hyper excitability of neuromuscular junction bringing in musclecramps and uterine hyperactivity. Objectives: To determine the mean serum magnesium levelsin women presenting with preterm labor. Study Design: Cross Sectional Study. Location andduration of study: Ziauddin University Hospitals, Karachi from 8th December 2015 to 7th June2016. Methodology: Total 40 women of age 18-40 years having singleton pregnancy between28-36 weeks gestation with established preterm labor having cervical dilatation less than 3cm.were included. 5ml blood was collected and analyzed. Outcome in terms of Mean StandardDeviation were noted. Descriptive statistics were applied. Stratification was done using studentt-test and ANOVA where appropriate. The p-value ≤0.05 was considered as significant. Results:The mean age was 26.25±2.38 years. Mean gestational age was 32.77±2.11 weeks. Meancervical dilatation was 1.85±0.39 cm. Mean serum magnesium level was found 1.43±0.25 mg/dl. The results showed that there was significant difference in mean serum magnesium level forgestational age but not significant for age, cervical dilatation, parity and gravida. Conclusion:The results showed that serum magnesium level reduced with increased gestational age.Preterm labor can be predicted by serum magnesium levels. 


Author(s):  
Khaled Alswat

IntroductionType 2 Diabetes (T2D) is a growing health problem nationally and worldwide. Magnesium (Mg) is an important mineral for a wide range of metabolic reactions. Here, our primary goal was to determine the prevalence of hypomagnesemia and its relationship to glycemic control, cardiovascular markers, and T2D-related complications.Material and methodsA cross-sectional study from September 2015 to March 2017 including patients with T2D who attended the Diabetes Center, Taif, Saudi Arabia. Those with known hypomagnesemia, type 1 diabetes, gestational diabetes, end-stage renal disease, and those on magnesium supplementations were excluded. Those with a serum magnesium level < 0.7 mmol/L were considered to have hypomagnesemia.ResultsA total of 285 patients with a mean age of 59.4 ± 12.7 years were enrolled. The majority of patients were female, with long-standing T2D, with a mean body mass index in the obesity category, and most of them had comorbid conditions. Twenty-eight percent of the screened T2D patients had hypomagnesemia and this group were more likely to have a bachelor degree (P = 0.034), to be on metformin, statin, and Glargine insulin (all P < 0.05), have worse glycemic control (P < 0.05), and a higher pulse rate (P = 0.039), but were less likely to be on diet control (P = 0.034) when compared to those with a normal Mg level.ConclusionsAlmost one-third of the screened T2D patients have hypomagnesemia. Hypomagnesemia was associated with the treatment modalities, worse glycemic control, and with peripheral artery disease.


2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Takayuki Fujii ◽  
JUNYA KOSHIZAKA ◽  
NOBUAKI YAMAUCHI ◽  
MAYU MORIMOTO ◽  
NORIKO TERASAKI ◽  
...  

Abstract Background and Aims Serum magnesium levels are an important factor associated with vital prognosis, cardiovascular disease, and vascular calcification in hemodialysis patients. Moreover, low serum magnesium levels are reportedly associated with an increased risk of hip fractures. Previously we reported that mean magnesium level during the first 3 years of hemodialysis was associated with all-cause mortality in ERA-EDTA 2018. Here, we investigated whether mean magnesium level during the first 3 years of hemodialysis can predict fracture risk. Method A retrospective cohort study was conducted in 283 patients who started hemodialysis at our hospital between March 2004 and the present and who could be followed for at least 3 years or had a fracture within 3 years. To assess the association between mean serum magnesium level during 3 years after the start of hemodialysis or until fracture and fracture risk, a multivariate analysis was performed using the Cox proportional hazard model with factors related to fractures as covariates, with all fractures such as hip fracture and spinal compression fracture as the outcome. Results The mean follow-up period was 6.1 years, and the mean age of patients was 64 years, with women accounting for 31%. Of all 283 patients, 62 developed fractures. A univariate analysis of factors associated with fractures revealed that high serum magnesium level was a significant fracture suppressor (hazard ratio [HR]: 0.31 [0.12–0.73]). Multivariate analysis conducted with significant factors in univariate analysis (mean serum albumin level, serum phosphorus level, hemoglobin level, C-reactive protein level, age, history of heart disease, history of bone fractures, and use or nonuse of phosphate binder during the 3 years) as the covariates revealed that the serum magnesium level was not significantly associated with bone fractures (HR: 0.95 [0.33–2.78]), whereas, old age, history of fractures, low albumin level, high CRP level, and nonuse of phosphate binder were significantly associated with fractures. Conclusion Serum magnesium levels during 3 years after the initiation of hemodialysis did not predict the risk of subsequent fractures, whereas a high level of inflammatory response, malnutrition, and nonuse of phosphate binder did.


2021 ◽  
Vol 28 (12) ◽  
pp. 1768-1772
Author(s):  
Muhammad Kamal ◽  
Farrukh Saeed ◽  
Muhammad Anwar ◽  
Sanuaullah Khan ◽  
Seemi Habib ◽  
...  

Objective: To determine the frequency of hypomagnesaemia in children under five year of age having acute diarrhea. Study Design: Descriptive Cross Sectional study. Setting: Department of Pediatric Medicine, Rashid Latif Medical College / Arif Memorial Teaching Hospital, Lahore. Period: August 2019 to January 2020. Material & Methods: A total of 96 children aged between 6 months to five years having acute diarrhea and duration of illness <14 days were enrolled. All the patients were subjected to measurement of serum magnesium level. The proportion of hypomagnesaemia was analyzed in acute diarrhea. The effect modifier and confounding variables were controlled through stratification of data on duration of illness less as < 14 days and more than 14 days, age as < 2 year or > 2 year and weight as < 2SD or > 2SD on weight for age chart. Chi square test was applied considering p value < 0.05 as significant. Results: Our study comprised of 96 patients having acute diarrhea, of these 96 study cases, 62 (64.6%) were boys and 34 (35.4%) were girls. Mean age of our study cases was 19.25±15.71 months. Mean weight of study cases was 9.56±3.01 kg. Mean duration of illness was 5.74 ± 3.26 days. Mean Serum Magnesium level was 1.63 ± 0.32 mg/dl (ranging from 1.0 mg/dl to 2.8 mg/dl). Hypomagnesaemia was present in 47 (49%) cases. Conclusion: High frequency of hypomagnesaemia was observed in children under 5 years of age having acute diarrhea. Duration of illness had significant impact on hypomagnesaemia. Serum magnesium levels must be regularly monitored in children with acute diarrhea.


2018 ◽  
Vol 25 (10) ◽  
pp. 1498-1502
Author(s):  
Zohaib Feroz ◽  
Abdul Raheem Memon ◽  
Nisar Ahmed Shah ◽  
Syed Zulfiquar Ali Shah

Objectives: To determine the frequency of hypomagnesemia in patients withdiabetic foot ulcer. Study Design: Cross sectional descriptive nature. Setting: Liaquat UniversityHospital Jamshoro / Hyderabad. Period: 29-09-2016 to 28-03-2017. Patients and Methods:The patients with history of diabetes mellitus (known cases) for more than 3 years durationhad diabetic foot ulcer for ≥ 02 weeks duration, of 30-60 years of age & either gender wererecruited and evaluated for serum magnesium level while the data was analyzed in SPSS 16.Results: Total 100 patients with diabetic foot ulcer were evaluated for hypomagnesaemia. Themean age ±SD of age (years), duration of diabetes (years) and foot ulcer (weeks), BMI (kg/m2),hypertension (systolic and diastolic mmHg), HBA1C and magnesium for whole population was52.86±6.87, 6.95±1.85 and 5.86±2.31, 31.92±2/43, 150.38±10.52 and 95.97±5.97, 9.96±2.73and 1.16±0.95 respectively. Out of one hundred, 55% were males and 45% were females. Thehypertension, smoking, dyslipidemia, obesity, raised HBA1C and hypomagnesemia was foundin 65%, 59%, 59%, 55%, 56% and 67%. Conclusion: Hypomagnesemia detected in subjectswith type 2 diabetes mellitus having foot ulcers.


2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Mehmet Bankir ◽  
Nedime Sahinoglu Keskek ◽  
Tayyibe Saler ◽  
Sakir Ozgur Keskek ◽  
Selim Cevher

2021 ◽  
Vol 10 (2) ◽  
pp. e21-e21
Author(s):  
Taraneh Esmaili ◽  
Zahra Aghaalitafreshi ◽  
Mohammad Hadi Gharib ◽  
Maryam Montazeri

Introduction: Atherosclerosis progression in the patients suffering from end-stage renal disease (ESRD) is more than normal population. Magnesium levels are also associated with an increase in atherosclerosis in the common carotid artery. Intima-media carotid calcification is either directly or indirectly related to cardiovascular disease and a higher rate of death among patients with chronic renal failure. Objectives: The purpose of the present study was to evaluate the protective role of serum magnesium levels in vascular calcification and the improvement of the carotid intima-media thickness (CIMT). Patients and Methods: In this cross-sectional research, the participants were selected from all patients with ESRD in Five Azar Medical Center of Gorgan, Iran. Blood samples collected from research units were tested for serum magnesium level in three times. Patients were referred to a radiologist to measure CIMT. Data collected in all patients were evaluated based on Spearman’s correlation test. Results: The correlation between serum magnesium level and CIMT was not statistically significant (P = 0.66 r= 0.04), however a positive correlation between CIMT and the dialysis adequacy (KT/V) was detected (r = 0.306, P = 0.006). Conclusion: This study demonstrated no correlation between the serum magnesium level and the CIMT in hemodialysis patients.


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