scholarly journals PROGNOSIS OF ACUTE FULMINANT HEPATIC FAILURE

2012 ◽  
Vol 19 (04) ◽  
pp. 496-500
Author(s):  
JAVED AHMED PHULPOTO

Acute fulminant hepatic failure (ALF) is a medical emergency and associated with high mortality rate. Its etiology showsconsiderable geographical variations. The viral causes are the most common in our region, [whilst acetaminophen (Paracetamol) inducedhepatotoxicity forms the most common precipitant in many developed countries]. Objective: To assess the causes and prognosis of acutefulminant hepatic failure in patients attending medical unit I, Ghulam Mohammad Mahar Medical college hospital, Sukkur. Study Design: Across-sectional study. Place of Study: Medical Unit-I, Ghulam Mohammad Mahar Medical College Hospital, Sukkur. Duration of Study: FromJanuary 2010 to July 2011. Methodology: A total one hundred twenty (120) patients of ALF were studied during the study period to evaluate thecauses and prognosis. Those patients who were admitted during the study period were included in the study. The selected patients presentedwith jaundice and hepatic encephalopathy of varying grades. Results: Almost all the cases the causative agents were viruses. Among these,the hepatitis E virus (HEV) was the top most causative agent followed by hepatitis B Virus (HBV) in this study. Despite good effort ofconservative treatment, the mortality rate was 77.5%. The mortality rate was higher in grade-III and grade-IV encephalopathy patients,whereas the prognosis is better in grade-1 and grade-II encephalopathy patients.

1970 ◽  
Vol 38 (2) ◽  
pp. 56-59
Author(s):  
N Islam ◽  
ABM Abdullah ◽  
A Zaman

Acute hepatic failure (ALF) is a medical emergency and infrequently presented in the hospitals and may be associated with high mortality rate. Its etiology shows considerable geographical variations. The viral causes are the most common worldwide, [whilst acetaminophen (Paracetamol) induced hepatotoxicity forms the most common precipitant in many developed countries.] A total forty (40) patients of ALF were studied during the period of January 2003 to July 2004 to evaluate the etiology and outcome. The patients were admitted in different tertiary care hospitals in Bangladesh. The patients were selected randomly by the diagnostic criteria. The selected patients presented with jaundice and hepatic encephalopathy of varying grades. Almost all the cases the causative agents were viruses. Among these, the hepatitis E virus (HEV) was the top most causative agent followed by hepatitis B virus (HBV) in this study. Despite good effort of conservative treatment, the mortality rate was 77.5%. The mortality rate was higher in grade-III and grade-IV encephalopathy patients whereas the prognosis is better in grade-I and grade-II encephalopathy patients.   DOI: 10.3329/bmj.v38i2.3575 Bangladesh Medical Journal 38(2) 2009 56-59


2017 ◽  
Vol 55 (8) ◽  
pp. 2406-2412 ◽  
Author(s):  
Samir K. Saha ◽  
Zabed B. Ahmed ◽  
Joyanta K. Modak ◽  
Hakka Naziat ◽  
Shampa Saha ◽  
...  

ABSTRACTGroup B streptococcus (GBS) infection is a leading cause of death among newborns in developed countries. Data on the burden of GBS in Asian countries are lacking. This study aimed to understand (i) the rate of maternal rectovaginal GBS carriage, (ii) the rate of vertical transmission of GBS, as determined by culturing ear, umbilicus, and nasal swabs, and (iii) the distribution of GBS serotypes. This prospective observational study was conducted between September 2012 and November 2013 at Kumudini Women's Medical College Hospital, a secondary-level hospital in Mirzapur, Bangladesh. The study enrolled pregnant women who visited the outpatient clinic for antenatal care (ANC) and/or delivered a child in the inpatient department of Kumudini Women's Medical College Hospital and the babies born to those mothers. Among 1,151 enrolled pregnant women, 172 (15% [95% confidence interval [CI], 13 to 17%]) carried GBS; among 68 babies born to mothers with carriage, 26 (38% [95% CI, 27 to 51%]) had GBS on their body surfaces, indicating vertical transmission. Typing of the isolates (n= 172) identified all 10 GBS serotypes, most commonly types Ia (40% [69/172 isolates]), V (23% [40/172 isolates]), II (14% [24/172 isolates]), and III (12% [20/172 isolates]). This study shows that Bangladesh has all of the ingredients for invasive GBS disease, including colonization of mothers by invasive serotypes and vertical transmission to babies.


2021 ◽  
Vol 15 (2) ◽  
pp. 62-64
Author(s):  
Swapan Kumar Mondal ◽  
Ananta Kumar Biswas ◽  
Swapna Biswas Joy ◽  
MM Shahin Ul Islam ◽  
Bablu Kumar Pal ◽  
...  

Postpartum Acute Kidney Injury (AKI) is one of the serious complications of pregnancy and is associated with high mortality and morbidity. Although Postpartum AKI has decreased markedly in developed countries in the last 50 years, but it is a challenging health problem in pregnant women, specially in the developing countries like Bangladesh. Aim of this study was to determine the contributing factors and outcome of postpartum AKI. This observational study was conducted in the department of nephrology, Faridpur Medical College Hospital from January 2018 to December 2019. During that study period thirty two patients with postpartum AKI were admitted in the above mentioned department. Demographic, clinical and laboratory data of those patients were recorded. Mean age of patients was 25.3 ± 4.2 years, and the 72% patients underwent cesarean section. Oliguria was the main presentation (91%). Puerperal sepsis (38%), postpartum hemorrhage (22%), and Eclampsia (16%) were the common contributing factors. Hemodialysis was required for most of the patients (75%). Therefore early diagnosis, identification and treatment of cause, timely initiation of renal replacement therapy is mandatory. Faridpur Med. Coll. J. 2020;15(2): 62-64


1970 ◽  
Vol 18 (2) ◽  
pp. 106-108 ◽  
Author(s):  
MH Haidary ◽  
Asgar Hussain ◽  
Safiuddin Ahmed ◽  
Abul Kasem

Birth asphyxia is an important cause of preventable cerebral injury in the neonatal period. It continues to be major cause of neonatal mortality and morbidity in both developing and developed countries. Recently a quite good number of birth asphyxiated new born babies had been admitted in the pediatric department of RMCH (Rajshahi Medical college Hospital). This study has been conducted to see the types and outcome of management of birth asphyxiated babies. A total 871 neonates were admitted in the pediatric department of RMCH from September 2001 to November 2002. Out of which birth asphyxia was 191 (21.92%) acute respiratory infection (ARI)-194 (22.73%), Low birth weight (LBW)-113 (12.97%), Neonatal jaundice-84 (9.64%), Septicaemia-38 (4.38%), Meningitis-26 (2.98%), Diarrhea-24 (2.75%), Birth trauma-24 (2.75%), Neonatal tetanus-04 (0.45%), Out of the total birth asphyxiated babies, mild type was 35 (18.32%), moderate type was 40 (20.94%), and severe birth asphyxia was 116 (60%), The recovery rate in mild birth asphyxia was (100%), in moderate case was (95%) and in severe case the rate was (74.13%).   doi: 10.3329/taj.v18i2.3176 TAJ 2005; 18(2):  106-108


2016 ◽  
Vol 11 (1) ◽  
pp. 15-19 ◽  
Author(s):  
ANM Saiful Hasan ◽  
Barun Kanti Biswas ◽  
Alok Kumar Saha ◽  
Lakshman Chandra Kundu ◽  
Mohammad Zahirul Islam Khan ◽  
...  

Very low birth weight (VLBW) is an important cause of infant mortality and still a challenge for achieving Millennium Development Goal (MDG) in Bangladesh. Our study was to see the risk factors and its outcome of VLBW neonates in a tertiary level Faridpur Medical College Hospital (FMCH), outside capital Dhaka. This prospective cross sectional study was conducted in neonatal Unit of pediatric department in FMCH. All neonates who were admitted here had been selected and we find out the very low birth weight neonates for our study purpose. All anthropometric measurements were taken by us in our department. We took all the informations about neonates within our study period of six months (November 2013 to April 2014) through a prescribed protocol. Total 1126 neonates admitted within our study period of 6 months. Among 1126 neonates 76 of them were VLBW. Among 76 VLBW neonates 38 (50%) were male and 38 (50%) were female, but 22 of them were expired, which was 28.94% of total VLBW neonates. Most expired on month of March which was 38.46%. Among expired VLBW neonates 10 (45.45%) of them were male and 12 (54.55%) of them were female. Total 48 (63.15%) mothers of VLBW neonates delivered at hospital of them Caesarean section occurs in 40 (52.63%) mothers of VLBW neonates and normal vaginal delivery (NVD) occurs in 36 cases (47.37%). Home delivery occurs in mothers of 28 VLBW neonates. Among them 15 (53.57%) were done by traditional birth attendance (TBA), 8 (28.57%) by local dai and 5 (17.86%) by relatives of the family of VLBW neonates. We found mothers of 41 (53.95%) VLBW neonates had premature rupture of membrane (PROM), 8 (10.53%) had eclampsia, 4 (5.26%) had leaking membrane and 4 (5.26%) had history of accident. Maternal age of VLBW neonates are more common between 18 to 24 years of age that was 53.95% (41 in number) but 27 mothers (35.52%) were below 18 years of age . We found in our study that the survival rate of VLBW neonates in our institute is not like developed countries but it is better than many developing countries around the world.Faridpur Med. Coll. J. Jan 2016;11(1): 15-19


1984 ◽  
Vol 51 (2) ◽  
pp. 165-171 ◽  
Author(s):  
B. D. Bhatia ◽  
N. B. Mathur ◽  
P. Handa ◽  
A. P. Dubey ◽  
M. Trivedi

2020 ◽  
Vol 22 (2) ◽  
pp. 110-117
Author(s):  
Md Mahmudul Islam ◽  
Khondkar AK Azad ◽  
Md Aminul Islam ◽  
Rivu Raj Chakraborty

Background: Chest trauma is responsible for 50% of deaths due to trauma. This kind of death usually occurs immediately after the trauma has occurred. Various therapeutic options have been reported for management of chest injuries like clinical observation, thoracocentesis, tube thoracostomy and open thoracotomy. Objective: To observe the pattern and outcome of management in chest trauma Methods: This is an observational study carried out in Casualty department of Chittagong Medical College Hospital (CMCH), Chittagong, between April 2015 to March 2016. Our study was included all patients, both sexes, following chest injury at Casualty units of Chittagong Medical College Hospital. All the data were recorded through the preformed data collection sheet and analyzed. Result: The mean age was found 37.7±18.1 years with range from 12 to 80 years. Male female ratio was 11.8:1. The mean time elapsed after trauma was found 6.1±3.1 hours with range from 1 to 72 hours. Almost one third (35.7%) patients was affecting road traffic accident followed by 42(27.3%) assault, 35(22.7%) stab injury, 15(9.7%) fall and 7(4.5%) gun shot . More than three fourth (80.5%) patients were managed by tube thoracostomy followed by 28(18.2%) observation and 2(1.3%) ventilatory support. No thoracotomy was done in emergency department. 42(27.2%) patients was found open pneumothorax followed by 41(26.6%) rib fracture, 31(20.1%) haemopneumothorax, 14(9%) simple pneumothorax, 12(7.8%) haemothorax, 6(3.9%) chest wall injury, 5(3.2%) tension pneumothorax, and 3(1.9%) flail chest. About the side of tube 60(39.0%) patients were given tube on left side followed by 57(37.0%) patients on right side, 9(5.8%) patients on both (left & right) side and 28(18.2%) patients needed no tube. Regarding the complications, 13(30%) patients had persistent haemothorax followed by 12(29%)tubes were placed outside triangle of safety, 6(13.9%) tubes were kinked, 6(13.9%) patients developed port side infection, 2(4.5%)tube was placed too shallow, 2(4.5%) patients developed empyema thoracis and 2(4.5%) patients developed bronchopleural fistula. The mean ICT removal information was found 8.8±3.6 days with range from 4 to 18 days. Reinsertion of ICT was done in 6(4.7%) patients. More than two third (68.2%) patients were recovered well, 43(27.9%) patients developed complication and 6(3.9%)patients died. More than two third (66.9%) patients had length of hospital stay 11-20 days. Conclusion: Most of the patients were in 3rd decade and male predominant. Road traffic accident and tube thoracostomy were more common. Open pneumothorax, rib fracture and haemopneumothorax were commonest injuries. Nearly one third of the patients had developed complications. Re-insertion of ICT needed almost five percent and death almost four percent. Journal of Surgical Sciences (2018) Vol. 22 (2) : 110-117


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