scholarly journals SPONTANEOUS BACTERIAL PERITONITIS

2018 ◽  
Vol 21 (04) ◽  
pp. 606-612
Author(s):  
Ahsan Ayub ◽  
Muhammad Ishfaq

Cirrhosis of liver is a chronic process characterized by structurally abnormalnodules in the liver, with diffuse generalized increased fibrous tissue in the liver. Spontaneousbacterial peritonitis(SBP) is a serious complication occurring in 10 to 30% of patients hospitalizedwith cirrhotic ascites. Objective: Assess the frequency of SBP in asymptomatic patients of livercirrhosis. Study design: Cross sectional study. Setting: Hepatitis clinic medical unit- 1 Serviceshospital, Lahore. Duration of study: One year. Sample size: Total 100 patients of cirrhoticascites. Results: Ten patients were found to have SBP (10%, 95% CI, 4.1 to15.9) and 90 patientswere found to have no SBP (90%, 95%CI, 84.1 to 95.9). Seven SBP patients (70%) had pyurea(Fisher’s exact test p- value< 0.01), and abnormal liver function tests (Chi square-value<0.01).Conclusions: We concluded that 10% of asymptomatic patients with cirrhotic ascites had SBP.SBP patients had significantly abnormal liver function tests and pyuria.

Endoscopy ◽  
2006 ◽  
Vol 38 (11) ◽  
Author(s):  
BJ Egan ◽  
S Sarwar ◽  
M Anwar ◽  
C O'Morain ◽  
B Ryan

2017 ◽  
Vol 73 (1) ◽  
pp. 23-28 ◽  
Author(s):  
Sunny Pathania ◽  
Navjyot Kaur ◽  
Sandeep Kumar ◽  
V.K. Sashindran ◽  
Pankaj Puri

2012 ◽  
Vol 12 (1) ◽  
Author(s):  
Eun Sun Jang ◽  
Sook-Hyang Jeong ◽  
Sung Ho Hwang ◽  
Hyun Young Kim ◽  
So Yeon Ahn ◽  
...  

2021 ◽  
Vol 7 (2) ◽  
pp. 90-94
Author(s):  
Afsana Yasmin ◽  
Rozina Akhter ◽  
Shahina Pervin Shapla ◽  
Laila Yeasmin

Background: Liver involvement in dengue infection is one of the clinical presentations. Objective: This study was undertaken to see severity of liver dysfunction in children with dengue infection. Methods: It is a cross sectional observational study conducted in 100 consecutive children with serologically positive dengue infection aged between 2 months to 14 years of age. Liver function tests were done in all patients and were studied the severity of deranged LFT with severity of dengue infection. Results: Out of 100 admitted children with dengue infection, deranged liver function tests found in 57(57.0%). ALT was above normal in 10 (29.4% of DF, 19 (57.6%) cases of DHF and 19(57.6%) cases of DSS respectively. AST was above normal level in 12(35.3%) cases of DF, 23(69.7%) cases of DHF and 22(66.7%) cases of DSS respectively. Low albumin was found in 41.0% of cases, 15(45.5%) cases of DHF and 19(57.6%) cases of DSS. INR was high only 4 cases of DSS. The bilirubin was normal in all cases except one died due to ALF due to DSS. The mean ALT and mean AST statistically higher in DHF and DSS in compare to DF (P-value 0.011 and 0.037) respectively. However, there was no significant difference in meal ALT and AST between DHF and DSS respectively. Overall mortality in 2 cases with DHF and DSS. Conclusion: Dengue infection is associated with variable level of liver dysfunction. The severity of liver dysfunction can predict the severity of dengue infection. Bangladesh Journal of Infectious Diseases 2020;7(2):90-94


Author(s):  
Salah Ahmed Mohamed Ali , Abdelraouf Ahmed Abass

The present study was conducted in Khartoum state (Sudan) as a cross-sectional study in 200 participants (100 smokers and 100 non-smokers), to investigate the effects of Cigarettes Smoking on Liver functions of Sudanese smokers. The smokers were categorized into either current smokers (70 participants) or past smokers (30 Participants). Parameters were analyzed by using spectrophotometer. From the results, the levels of liver function tests (TB, Albumin and globulin) were significantly higher in non-smokers (6.0, 3.6 and 2.43 g/dl) as compared to current smokers (4.4, 2.4 and 1.98 g/dl) and past smokers (4.7, 2.7 and 1.93 g/dl). Meanwhile, ALT was significantly increased in current and past smokers as compared to non-smokers, where as AST was significantly higher in current smokers as compared to non-smokers, while there was no significant difference between current and past smokers as well as between past and non-smokers for this parameter. In addition, heavy and long duration of smoking were both associated with low total protein, albumin and AST levels .Also liver function tests were not significantly differing in current smoker's non-diabetics and non-smokers diabetics except total protein. From the results when, liver enzymes raised that may lead to increase proteins metabolism and increase blood glucose. These signs may place cigarettes smoking one of the top causes of hepatitis, pancreatitis, insulin resistance and finally diabetes mellitus type II. On the other hand, smoking cessation in diabetics lead to decrease the risk of hepatitis, Also regular physical activity and using medication regularly in diabetics lead to the same actions above; in addition diabetes complications were decreased.


2021 ◽  
Vol 10 (8) ◽  
pp. 1730
Author(s):  
Hiroshi Miyama ◽  
Yasuyuki Shiraishi ◽  
Shun Kohsaka ◽  
Ayumi Goda ◽  
Yosuke Nishihata ◽  
...  

Abnormal liver function tests (LFTs) are known to be associated with impaired clinical outcomes in heart failure (HF) patients. However, this implication varies with each single LFT panel. We aim to evaluate the long-term outcomes of acute HF (AHF) patients by assessing multiple LFT panels in combination. From a prospective multicenter registry in Japan, 1158 AHF patients who were successfully discharged were analyzed (mean age, 73.9 ± 13.5 years; men, 58%). LFTs (i.e., total bilirubin, aspartate aminotransferase or alanine aminotransferase, and alkaline phosphatase) at discharge were assessed; borderline and abnormal LFTs were defined as 1 and ≥2 parameter values above the normal range, respectively. The primary endpoint was composite of all-cause death or HF readmission. At the time of discharge, 28.7% and 8.6% of patients showed borderline and abnormal LFTs, respectively. There were 196 (16.9%) deaths and 298 (25.7%) HF readmissions during a median 12.4-month follow-up period. The abnormal LFTs group had a significantly higher risk of experiencing the composite outcome (adjusted hazard ratio: 1.51, 95% confidence interval: 1.08–2.12, p = 0.017), whereas the borderline LFTs group was not associated with higher risk of adverse events when referenced to the normal LFTs group. Among AHF patients, the combined elevation of ≥2 LFT panels at discharge was associated with long-term adverse outcomes.


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