A quality control towards the production of Crude Palm Oil (CPO) production is a prominent instanceto be held by companies. Through Taguchi method, several steps are conducted start with the selection of factorsthat affect the quality of CPO and factor level values which then become the basis in the selection of orthogonalmatrices. Based on the result of the research, it is found that the factors that significantly influence the quality ofCPO are boiling pressure, boiling temperature and clarification unit temperature. After applying the optimalcombination of settings based on the Taguchi method, the overall proportion of overall defects decreased by10.42%.Keywords: CP