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2021 ◽  
Vol 49 (8) ◽  
pp. 666-674
Author(s):  
Alaa Quisi ◽  
◽  
Huda Almadhoun ◽  
Gökhan Alıcı ◽  
Ömer Genç ◽  
...  

2021 ◽  
pp. 096372142110441
Author(s):  
Joshua D. Miller ◽  
Mitja D. Back ◽  
Donald R. Lynam ◽  
Aidan G. C. Wright

Narcissism is of great interest to behavioral scientists and the lay public. Research across the past 20 years has led to substantial progress in the conceptualization, measurement, and study of narcissism. This article reviews the current state of the field, identifying recent advances and outlining future directions. Advances include hierarchical conceptualizations of narcissism across one-factor (narcissism), two-factor (grandiose vs. vulnerable narcissism), and three-factor (agentic extraversion, antagonism, narcissistic neuroticism) levels; the development of measures to assess the components of narcissism; clarification of the relations between narcissism and self-esteem; an understanding of the behavioral and motivational dynamics underlying narcissistic actions and social outcomes; and insight regarding potential fluctuations between narcissistic states. Future directions point in general to increased research using the lower levels of the narcissism hierarchy, especially the three-factor level. At this level, more research on the etiology, heritability, stability, and centrality of the three components is required.


2021 ◽  
Author(s):  
Hiroaki Tanaka ◽  
Kayo Tanaka ◽  
Sho Takakura ◽  
Naosuke Enomoto ◽  
Shintaro Maki ◽  
...  

Abstract Objective: Here, we tested the correlation between maternal placental growth factor (PlGF) and fetal heart rate (FHR) monitoring findings. Methods: We included 35 women with single pregnancies from 35 to 42 weeks of gestation who were hospitalized due to onset of labor. Blood samples were collected at the start of labor. Intrapartum FHR monitoring parameters included total deceleration area, average deceleration area (mean deceleration area per 10 minutes), and five-tier classification level. Results: Of the 35 women, 26 (74%) had vaginal delivery and 9 (26%) had cesarean section. After excluding 2 women who had cesarean section for arrest of labor, we analyzed 26 women who had vaginal delivery (VD group) and 7 who had cesarean section for fetal indications (CSF group). PlGF level was significantly higher in the VD group (157 ± 106 pg/ml) than in the CSF group (74 ± 62 pg/ml) (P = 0.03). There were no significant correlations between PlGF and total (r = -0.07) or average (r = -0.08) deceleration area. A significant negative correlation was observed between PlGF and the proportion of five-tier classification level 3 or higher (r = -0.42). Conclusion: PlGF was correlated with FHR monitoring findings and might be a promising biomarker of intrapartum fetal function.


2021 ◽  
Author(s):  
Josh Miller ◽  
Mitja Back ◽  
Donald Lynam ◽  
Aidan G.C. Wright

Narcissism is of great interest to behavioral scientists and the lay public. Research across the last 20 years has led to substantial progress in the conceptualization, measurement, and study of narcissism. The present paper reviews the current state of the field, identifying recent advances and outlining future directions. Advances include hierarchical conceptualizations of narcissism across one (narcissism), two (grandiose vs. vulnerable narcissism), and three factor levels (agentic extraversion, antagonism, narcissistic neuroticism), the development of measures to assess the components of narcissism, clarification of the relations between narcissism and self-esteem, an understanding of the behavioral and motivational dynamics underlying narcissistic actions and social outcomes, and insight regarding potential fluctuations between narcissistic states. Future directions point in general to increased research using the lower levels of the narcissism hierarchy, especially the three-factor level. At this level, more research is required on the etiology, heritability, stability, and centrality of the three components.


2021 ◽  
Vol 13 (1) ◽  
pp. 27
Author(s):  
Mella Apriyani ◽  
Jajang Jajang ◽  
Agustini Tripena Br. Sb.

There are three types of  Tuberculosis (TB) patients at Banyumas Region Hospital, namely negative  pulmonary TB, positive pulmonary TB, and extra pulmonary TB. Types of TB generally caused by age, cae of history, gender, level of education, and domicile. One of the methods that used to find a correlation between types of TB with the affect is regression analysis. This study used multinomial logistic regession analysis because types of TB is categorical and the data is 156 TB’s patients recorded at 2018/2019. The result showed that the level of education be a dominant factor to affect TB. Here, we noted that patients with basic education level have a 5,843 time odds for getting positive pulmonary TB and 2,224 times for getting extra pulmonary TB. The multinomial logistic regression model is then given as probability for getting positive pulmonary TB with factor level of education is greather than negative pulmonary TB and extra pulmonary TB.


2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Miwako Yoshimoto ◽  
Nobuhiko Takeda ◽  
Takayuki Yoshimoto ◽  
Shun Matsumoto

Abstract Background Intravitreal injections of anti-vascular endothelial growth factor are commonly used to treat macular diseases, including diabetic macular edema. Anti-vascular endothelial growth factor drugs can enter the systemic circulation after intravitreal injections and appear to suppress circulating vascular endothelial growth factor levels. However, whether this can cause any systemic adverse events remains unknown. Case presentation A 70-year-old Japanese man diagnosed with diabetic macular edema in both eyes was treated with anti-vascular endothelial growth factor intravitreal injections. One month after receiving two intravitreal injections of aflibercept 1 week apart for diabetic macular edema in both eyes, he complained of a severe acute headache. The patient was diagnosed with hypertensive cerebral hemorrhage of the occipital lobe based on an elevated blood pressure of 195/108 mmHg and the results of computed tomography and magnetic resonance imaging of his brain. The patient was treated with an intravenous injection of nicardipine hydrochloride to lower his systemic blood pressure. Two days after the stroke, the patient began oral treatment with 80 mg/day telmisartan, which was continued for 3 days, and the telmisartan dose was reduced to 40 mg/day thereafter. His blood pressure promptly dropped to 130/80 mmHg, and his severe headache disappeared. One year after the cerebrovascular stroke, the telmisartan was discontinued because his blood pressure stabilized at a normal level. His plasma vascular endothelial growth factor levels were measured via specific enzyme-linked immunosorbent assay before and after the intravitreal injections of aflibercept. Immediately before the injections, the vascular endothelial growth factor level was 28 pg/ml, but it rapidly fell below the detection limit within 1 week, where it remained for over 2 months. Two days before the cerebral hemorrhage, his plasma vascular endothelial growth factor level was below the detection limit, and 2 months later after the stroke, his plasma vascular endothelial growth factor level recovered to 41 pg/ml. Conclusion This case suggests that hypertension and resultant cerebral hemorrhage can occur in patients with diabetic macular edema when plasma vascular endothelial growth factor levels are systemically decreased below the detection limit for a prolonged time after local injections of anti-vascular endothelial growth factor agents into the vitreous cavity. Therefore, severely reduced plasma vascular endothelial growth factor levels could be a higher risk factor to develop generally infrequent stroke. Ophthalmologists should be aware of possible severe reduction of plasma vascular endothelial growth factor levels and resultant increase in blood pressure after intravitreal injections of an anti-vascular endothelial growth factor drug. If the plasma vascular endothelial growth factor levels could be monitored more easily and quickly during the treatment, it would help to prevent adverse events.


Author(s):  
Florian Hermet ◽  
Nicolas Binder ◽  
Jérémie Gressier ◽  
Gonzalo Sáez-Mischlich

A preliminary analysis of turbine design, fit for pulsed flow, is proposed in this paper. It focuses on an academic 2D configuration using inviscid flows, since pressure loads due to wave propagation are several orders of magnitude higher than friction and viscous effects do not significantly impinge on the inviscid part, as previously shown by Hermet, 2021. As such, a large parametric study was carried out using the design of experiments methodology. A performance indicator adapted to unsteady environment is carefully defined before detailing the factors chosen for the design of experiments. Since the number of factors is substantial, a screening design to identify the factors influence on the output is first established. The non-influential factors are then omitted in a more quantitative study of the output law. The surface response calculation allows determining the factor level favouring the best output. Consequently, the main trends in the turbine design driven by a pulsed flow can be stated.


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