scholarly journals Post-surgery Quality of Life in Patients with Acromegaly Using SF36 Quality of Life Questionnaire-prospective Study

2021 ◽  
Vol 3 (2) ◽  
pp. 34
Author(s):  
Manoj Gedam ◽  
Dipti Sarma
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Complete Remission ◽  
Life Questionnaire ◽  
Quality Of Life Questionnaire ◽  
Role Physical ◽  
Post Surgery ◽  
Sf 36 ◽  
Significant Difference

Introduction: Acromegaly is chronic progressive disease with multisystem involvement characterised by an excess secretion of growth hormone and increased circulating insulin like growth factor 1 concentration.Aims and Objectives: To assess surgical outcome of acromegaly patients at tertiary care institute using SF 36 quality of life questionnaire. SF-36 scores comprise 3 components: the physical component summary (PCS), the mental component summary (MCS) and role-social component summary (RCS).30 acromegaly patients admitted in Guwahati medical college were enrolled in study and followed up post operatively for surgical remission. All participants completed the SF-36 preoperatively, 1 year and 2 years postoperatively.Material and Method: Out of 30 patients 6 patients had surgical remission post operatively on the basis of postoperative glucose suppressed GH Level done after 12 weeks. Preoperatively subscale scores (physical functioning, role physical, general health) which were below the set standards for the normal population show significant postoperative improvements along with mental health (MH) scores. Similarly, PCS, MCS and RCS scores changed significantly after surgery. We also compared the QOL of 6 patients whose peak GH level was < 0.4 µg/L during postoperative oral glucose tolerance testing with those patients whose nadir GH level was ≥ 0.4 µg/L. There was significant difference between partial and complete remission group in subscale score role physical, social function and mental health. Similarly, PCS and RCS score significantly different in partial and complete remission group than MCS score.Conclusions: QOL is considerably reduced in patients with acromegaly compared to general population which improves significantly after surgical treatment. Patients achieving the new remission criteria had significant improvement in physical and social components than those who did not.

scholarly journals Yoga Versus Physical Therapy In Multiple Sclerosis: Randomized Controlled Trial

2021 ◽  
Author(s):  
Elena Lysogorskaia ◽  
Timur Ivanov ◽  
Elena Ulmasbaeva ◽  
Aynagul Mendalieva ◽  
Maxim Youshko ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Therapy ◽  
Waiting List ◽  
Life Questionnaire ◽  
Walking Test ◽  
Quality Of Life Questionnaire ◽  
Sf 36 ◽  
Significant Difference ◽  
The Impact

Abstract Background. Yoga originated in the territory of modern India more than 3000 years ago and uses techniques for working with the musculoskeletal system, cardiorespiratory system and attention. Currently, the effectiveness and safety of yoga in patients with various neurological disorders, including MS, is of interest to many scientists and clinicians. The main aim of this study is to examine the effect of yoga on symptoms and quality of life in patients with MS versus physical therapy (exercise therapy) and no exercise.Methods. The patients were randomly assigned to 3 groups (yoga, PT, or waiting list), patients from the waiting list had an opportunity to enter the yoga program after the end of the trial period. After 12 weeks of regular exercises (or absence of them), the effect of yoga and PT on the functional status and quality of life of patients were evaluated. The MS treatment was a part of routine practice, as prescribed by the treating neurologist. The data was collected during the patients’ two visits to the study center - before the start of the study and at the end of the 12-week period. The in-person examination included a doctor's assessment of the EDSS, the SF-36 quality of life questionnaire, the fatigue scale, the Berg balance scale, the 6-minute walking test.Results. A total of 36 patients finished the clinical study: 30 women and 6 men. There was no statistically significant difference between the groups in terms of improvement in MS symptoms as measured by the balance, walking test and fatigue scales. However, in the analysis of the 8 criteria of SF-36 quality-of-life questionnaire the covariation analysis statistically significant differences were found in favor of the yoga group in terms of physical functioning (PF) (p=0.003), life activity (VT) (p<0.001), mental health (MH) (p=013), social functioning (SF) (p=0.028). Conclusions. Thus, regular yoga classes under the guidance of qualified staff are a promising method of non-drug rehabilitation of patients with MS with motor disorders. More research is needed to examine the impact of yoga on clinical patient improvement and quality of life indicators.Trial registration. ISRCTN15486200 https://doi.org/10.1186/ISRCTN15486200

Effectiveness analysis of the new method of antireflux surgery in patients with hiatal hernia

2020 ◽  
Vol 26 (4) ◽  
pp. 50-55
Author(s):  
A.R. Stasyshyn ◽  
◽  
A.A. Hurayevskyy ◽  
Yu.Y. Holyk ◽  
◽  
...  
Keyword(s):  
Quality Of Life ◽  
Los Angeles ◽  
Hiatal Hernia ◽  
Antireflux Surgery ◽  
New Method ◽  
Life Questionnaire ◽  
Post Surgery ◽  
Group I ◽  
Significant Difference

Aim. To analyze the effectiveness of a new method of antireflux surgery in patients with hiatal hernia. Materials and Methods. The results of treatment of 157 patients with hiatal hernia from 2016 to 2020 are analyzed. The patients were divided into 3 groups: group I, N=59, underwent laparoscopic antireflux operation modified by the authors (Patent of Ukraine № 59772); group II (N=77), underwent laparoscopic Nissen fundoplication; and group III (N=21) - laparoscopic Toupet fundoplication. Results and Discussion. At 36 months post-surgery follow-up, there was a statistically significant difference in favor of group I on the average scores of the visual analog scale for reflux symptoms, dysphagia and extraesophageal symptoms; the average quality of life questionnaire scores; the average DeMeester index; distribution of the patients by satisfaction; distribution of the patients by degree of reflux esophagitis according to the Los Angeles classification; and distribution by gas-bloat syndrome. Conclusions. Clinical application of the developed new method of laparoscopic surgery for hiatal hernia reduces the number of relapses and complications after surgery, and improves the quality of life of patients. Key words: hiatal hernia, antireflux surgery, new methods of treatment

scholarly journals Effect of targeted physiotherapy on the quality of life of patients with epilepsy of unknown etiology – a pilot study

2021 ◽  
Vol 24 (2) ◽  
Author(s):  
Elżbieta Szczygieł-Pilut ◽  
Elżbieta Mirek ◽  
Magdalena Filip ◽  
Daniel Pilut ◽  
Szymon Pasiut ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Therapy ◽  
Unknown Etiology ◽  
Study Group ◽  
Life Questionnaire ◽  
Quality Of Life Questionnaire ◽  
Sf 36 ◽  
Generalized Epilepsy ◽  
Patients With Epilepsy

Introduction: Epilepsy is one of the most common diseases of the central nervous system. According to the World Health Organization, it accounts for 1% of the global burden of disease worldwide. Pharmacotherapy remains the primary therapeutic tool in this disease. However, more and more emphasis is placed on approaching this group of patients in an interdisciplinary manner, taking their various needs into account: social, professional, economic or psychological. Attention is also paid to the positive impact of physical activity on the quality of life of patients with epilepsy. The patients with diagnosed epilepsy often complain of a feeling of instability not reflected in standard neurological examination. Early detection of postural control disorders is possible using an objective research tool which is the modified CTSIB test (Clinical Test of Sensory Interaction and Balance). Aim of the study: The aim of the study was to assess the influence of targeted physical therapy on the quality of life among patients with diagnosed epilepsy of unknown etiology using the SF-36 quality of life questionnaire. Materials and methods: The study included 11 professionally active adults with diagnosed generalized epilepsy of unknown etiology, treated at the Department or Outpatient Clinic of Neurology at John Paul II Specialist Hospital in Kraków. Finally, out of the 11 recruited patients (5 women and 6 men), 1 patient was excluded from the study due to a history of craniocerebral trauma. Patients were examined 3 times every month using EEG and the SF-36 quality of life questionnaire. Additionally, between the 2nd and the 3rd month of the pilot study, the study group underwent physical therapy focused on balance disorders using the Biodex SD stabilometric platform. Results: Overall, the quality of life index measured using the SF-36 quality of life questionnaire in the study group improved after the completion of targeted physical therapy. Conclusions: 1. Generalized epilepsy of unknown etiology results in a significant deterioration in the quality of life of patients, which may also be accompanied by disorders of postural control. 2 A targeted program of physiotherapy in the treatment of patients with generalized epilepsy of unknown etiology may has a positive effect on their quality of life. null

Clinical Frailty Scale: translation and cultural adaptation into the Brazilian Portuguese language

2020 ◽  
pp. 1-6
Author(s):  
M.K. Rodrigues ◽  
I. Nunes Rodrigues ◽  
D.J. Vasconcelos Gomes da Silva ◽  
J.M. de S. Pinto ◽  
M.F. Oliveira
Keyword(s):  
Quality Of Life ◽  
Cultural Adaptation ◽  
Brazilian Portuguese ◽  
Life Questionnaire ◽  
Clinical Frailty Scale ◽  
Quality Of Life Questionnaire ◽  
Sf 36 ◽  
Senior Patients ◽  
Translation And Cultural Adaptation

Background: Frailty is a biological syndrome that causes adverse events in the health of older adults. However, the Clinical Frailty Scale has not yet been culturally adapted and validated into Brazilian Portuguese language. Objectives: Our aim was to translate, reproduce and validate the Clinical Frailty Scale (CFS) for the Brazilian Portuguese language. Design: An observational cross-sectional study with senior patients was conducted between Jan 2018 and Nov 2018. Setting and Participants: Volunteers aged >60 and living in Brazil. The translation and cultural adaptation of the CFS into the Portuguese language, the principles and good practices were followed. Measurements: To conduct the validation and determine the reproducibility of an inter-observer evaluation, the patients answered the scale questions in Portuguese on two occasions, delivered by two separate examiners and separated by a 10-minute interval, on their first visit; the 36-item Short Form Survey quality-of-life questionnaire (SF-36) was also applied. Seven days later, a second visit was undertaken to perform an intra-observer reproducibility assessment. Results: A total of 66 older individuals were enrolled (72 ± 8 years), the majority of which did not present frailty (63.6%) and reported a low physical limitation level in the SF-36. The CFS showed a significant correlation with the SF-36 quality-of-life questionnaire (r= −0.663; p<0.0001) and no statistical difference was observed between intra-rater (p=0.641) and inter-rater (p=0.350) applications, demonstrating the reproducibility and applicability of the instrument. The standard error estimate (SEE) was evaluated and there were no differences between the CFS and the SF-36 (SEE= 1.13 points). Conclusion: The Brazilian Portuguese language version of the CFS is a valid, reproducible and reliable instrument for evaluating the impact of frailty on the lives of senior patients.

scholarly journals Mental health state and quality of life questionnaire in low vision assessment: a case report

2014 ◽  
Vol 7 (1) ◽  
Author(s):  
Rokiah Omar ◽  
Mohd Harimi Abd Rahman ◽  
Victor Feizal Knight ◽  
Mushawiahti Mustaphal ◽  
Zainora Mohammed
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Case Report ◽  
Low Vision ◽  
Health State ◽  
Life Questionnaire ◽  
Quality Of Life Questionnaire ◽  
Vision Assessment

Psychological manifestation in adolescents with thalassemia

2011 ◽  
Vol 26 (S2) ◽  
pp. 276-276
Author(s):  
H. Dessoki ◽  
T. Elhifnawy ◽  
O. Ezzat
Keyword(s):  
Quality Of Life ◽  
Outpatient Clinic ◽  
Depression Scale ◽  
Structured Interview ◽  
Life Questionnaire ◽  
Cross Sectional ◽  
Quality Of Life Questionnaire ◽  
Middlesex Hospital ◽  
Significant Difference

Objectiveβ-thalassemia major and its complications carry a significant psychological impact, causing emotional burden, hopelessness, and difficulty with social integration.MethodCross-sectional study which includes thirty adolescents with diagnosis of thalassemia & another group of thirty adolescents from gastrointestinal outpatient clinic were selected. All participants were subjected to Semi structured interview, Patient Health Questionnaire, Hospital Anxiety Depression Scale, Middlesex Hospital Questionnaire, and McGill Quality of Life Questionnaire.ResultsThalassemic adolescents shows statistically significant higher depression (p < 0.001), and higher anxiety (p < 0.001) compared to adolescents from gastrointestinal outpatient clinic. There was highly statistical significant difference regarding Middlesex Hospital Questionnaire (p < 0.001), and McGill Quality of Life Questionnaire. (p < 0.001).ConclusionDepressive and anxiety disorders were more prevalent among adolescents with thalassemia. Also, among the same group there was higher degree of Free Floating Anxiety, Phobic Anxiety, Obsessive Symptoms, Somatic Symptoms, Depressive Symptoms, and hysteria. Quality of life was highly affected among adolescents with thalassemia.

scholarly journals QUALITY OF LIFE IN DEPRESSIVE PATIENTS FOLLOWED IN PSYCHOLOGY AND IN PSYCHIATRY

2017 ◽  
Vol 6 (1) ◽  
pp. 97
Author(s):  
Sandrine Martins Antunes ◽  
Lisete Dos Santos Mendes Monico
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Physical Function ◽  
Physical Performance ◽  
Depressive Symptomatology ◽  
Life Questionnaire ◽  
Role Emotional ◽  
Sf 36 ◽  
Depressive Patients

Abstract.This study aims to analyze and compare the Quality of Life in patients followed exclusively in Psychiatry and in patients followed exclusively in Psychology. Took part of the study 60 patients of both genders with depressive symptomatology and no other clinical diagnosis (exclusion criteria), 30 being exclusively followed at hospital psychiatric consultations and 30 exclusively followed in psychology consultations. After informed consent, we used the Quality of Life questionnaire (SF-36; Ware & Sherbourne, 1992), which showed good psychometric properties in its nine domains: Physical Function, Physical Performance, Body Pain, General Health, Vitality, Social Functioning, Role Emotional, Mental Health, and Health Change. We found that the patients followed in Psychology showed a better quality of life in Emotional and Physical Performance, as well as in Mental Health. Men expressed a similar quality of life to women, except in the field of Physical Function, higher in males. Single patients had better in Role Emotional and Mental Health, when compared to divorced and widowed. The results are discussed considering the benefits of psychological therapy in improving the quality of life of depressed patients.Keywords: Quality of life; Patients; Psychology; Psychiatry.Resumo.O presente estudo pretende analisar e comparar a Qualidade de Vida em pacientes exclusivamente acompanhados em consultas psiquiatria e em pacientes exclusivamente acompanhados em consultas de psicologia. Participaram no estudo 60 pacientes de ambos os sexos com sintomatologia depressiva e sem outro quadro clínico diagnosticado (critério de exclusão), sendo 30 exclusivamente acompanhados em consultas hospitalares de psiquiatria e 30 exclusivamente acompanhados em consultas de psicologia. Após consentimento informado, aplicámos o Questionário da Qualidade de Vida (SF-36; Ware & Sherbourne, 1992), que mostrou boas propriedades psicométricas nos nove domínios constituintes: Função física, Desempenho físico, Dor corporal, Saúde geral, Vitalidade, Função Social, Desempenho emocional, Saúde mental e Mudança de Saúde. Verificámos que os pacientes acompanhados em Psicologia mostraram uma melhor Qualidade de Vida ao nível dos domínios Desempenho emocional, Desempenho físico e Saúde mental. Os homens manifestaram uma Qualidade de Vida semelhante à das mulheres, excepto no domínio da Função física, superior no sexo masculino. Os pacientes solteiros apresentaram melhores Desempenho emocional e Saúde mental comparativamente aos divorciados e aos viúvos. Os resultados são discutidos numa abordagem dos benefícios da terapia psicológica na melhoria da qualidade de vida em doentes deprimidos.Palavras-chave: Qualidade de Vida; Pacientes; Psicologia; Psiquiatria

scholarly journals The role of folded fibular flap in patients’ reconstruction of mandibular defects: a retrospective clinical study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ning Gao ◽  
Kun Fu ◽  
Jinghua Cai ◽  
Hao Chen ◽  
Wei He
Keyword(s):  
Quality Of Life ◽  
Psychological Health ◽  
Short Form ◽  
Life Questionnaire ◽  
Preoperative Level ◽  
Sf 36 ◽  
Retrospective Clinical Study ◽  
Significant Difference ◽  
Fibular Flap

AbstractThis study has analyzed 41 patients with mandibular ameloblastoma who underwent a partial mandibulectomy and reconstruction by folding the free fibular flap. In the preoperative and postoperative (6 months and 24 months after surgery), the Quality of Life (QOL) of these patients was assessed by using the University of Washington Quality of Life Questionnaire (UW-QOL) and the medical outcome study short form-36 (SF-36) questionnaires. SPSS 20.0 statistical software was used to conduct statistical analysis on the base data of the two groups of patients. Independent sample t test was conducted for sf-36 and UW-QOL scores at two time points in each group. The SF-36 survey showed that body pain (54.54 ± 8.10), general health (55.27 ± 7.54), and health changes (58.29 ± 9.60) decreased significantly at 6 months after surgery, but the mean score at 24 months after surgery all exceeded the preoperational level. At 24 months after the surgery, the vitality (80.41 ± 3.74), social function (81.61 ± 4.07), emotional role (82.39 ± 4.07), psychological health (81.66 ± 4.37) and total score (704.00 ± 31.53) all returned to the preoperative level, which was statistically significant compared with 6 months after surgery. However, there was no significant difference compared with the preoperative level. The UW-QOL survey showed that chewing (56.68 ± 7.23), speech (54.54 ± 7.7) and taste (62.29 ± 10.15) have significantly changed at 6 months after the surgery, and the difference was statistically significant at 24 months after surgery. Saliva generation decreased slightly (80.76 ± 3.35) at 6 months after surgery, but quickly returned to the preoperative level (81.59 ± 4.06). The total score of the patients almost recovered to the preoperative level at 24 months after surgery. The folded the fibular flap can not only repair the defects of soft tissue and bone tissue, but also restore the height of the alveolar ridge to, avoid the imbalance of crown and root ratio after implantation and reduce the occurrence of peri-implant inflammation, so that a true functional reconstruction can be realized.

Quality of life after total laryngectomy: evaluating the effect of socioeconomic status

2019 ◽  
Vol 133 (2) ◽  
pp. 129-134 ◽  
Author(s):  
A J Scott ◽  
J K McGuire ◽  
K Manning ◽  
L Leach ◽  
J J Fagan
Keyword(s):  
Quality Of Life ◽  
Socioeconomic Status ◽  
Private Sector ◽  
Total Laryngectomy ◽  
Illness Perception ◽  
Life Questionnaire ◽  
Quality Of Life Questionnaire ◽  
Significant Difference ◽  
Related Quality

AbstractObjectiveTotal laryngectomy is considered the primary treatment modality for advanced laryngeal carcinoma. This study assessed the quality of life in patients after total laryngectomy, and ascertained whether quality of life is affected by socioeconomic status.MethodForty-seven patients (20 state- and 27 private-sector) who underwent total laryngectomy between 1998 and 2014 responded to the University of Washington Quality of Life Questionnaire, the Voice-Related Quality of Life Questionnaire and the Brief Illness Perception Questionnaire.ResultsSignificant differences were found in socioeconomic status between state- and private-sector patients (p < 0.001). There was no significant difference in overall quality of life between groups (p = 0.210). State-sector patients scored significantly higher Voice-Related Quality of Life Questionnaire scores (p = 0.043). Perception of illness did not differ significantly between groups.ConclusionOverall quality of life after total laryngectomy appears to be similar in patients from different socioeconomic backgrounds. However, patients from lower socioeconomic circumstances have better voice-related quality of life. The results illustrate the importance of including socioeconomic status when reporting voice outcomes in total laryngectomy patients.

Assessment of Quality of Life in MA.17: A Randomized, Placebo-Controlled Trial of Letrozole After 5 Years of Tamoxifen in Postmenopausal Women

2005 ◽  
Vol 23 (28) ◽  
pp. 6931-6940 ◽  
Author(s):  
Timothy J. Whelan ◽  
Paul E. Goss ◽  
James N. Ingle ◽  
Joseph L. Pater ◽  
Dongsheng Tu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bodily Pain ◽  
Response Analysis ◽  
Life Questionnaire ◽  
Change Scores ◽  
Estrogen Synthesis ◽  
Sf 36 ◽  
Significant Difference ◽  
The Impact

Purpose To evaluate the impact of letrozole compared with placebo after adjuvant tamoxifen on quality of life (QOL) in the MA.17 trial. Methods Patients completed the Short Form 36-item Health Survey (SF-36) and the Menopause Specific Quality of Life Questionnaire (MENQOL) at baseline, 6 months, and annually. Mean change scores from baseline were compared between groups for summary measures and domains. A response analysis compared the proportion of patients who demonstrated an important change in QOL. Results Of 5,187 randomly assigned women in the trial, 3,612 (69.9%) participated in the QOL substudy: 1,799 were allocated to placebo and 1,813 were allocated to letrozole. No differences were seen between groups in mean change scores from baseline for the SF-36 physical and mental component summary scores at 6, 12, 24, and 36 months. Small (< 0.2 standard deviations) but statistically significant differences in mean change scores from baseline were seen for the SF-36 domains of physical functioning (12 months), bodily pain (6 months) and vitality (6 and 12 months), and the MENQOL vasomotor (6, 12, and 24 months) and sexual domains (12 and 24 months). On the response analysis, a significant difference was seen between groups for the bodily pain domain (percentage of patients reporting a worsening of QOL, 47% placebo v 51% letrozole; P = .009) and the vasomotor domain (22% placebo v 29% letrozole; P = .001). Conclusion Letrozole did not have an adverse impact on overall QOL. Small effects were seen in some domains consistent with a minority of patients experiencing changes in QOL compatible with a reduction in estrogen synthesis.

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