Discontinuity: A compositional approach to the dynamic decoupling of gesture and sound in live performance

<p>The gestural-sonorous object, as described by Rolf Inge Godøy, has experienced a gradual aesthetic splitting in New Music practices. The notion that physical gesture relates to sounding result in a linear, cause-and-effect fashion can no longer be taken as a pre-condition in the study of compositional thought, as New Complexity conceives of ever more diverse modes of instrumentally focussed sound production, while the New Discipline eschews musical tropes altogether. This thesis formulates a new model of information flow in performance, to facilitate an understanding of the role physical gesture plays in the interpretative processes involved in the creation of bodily and cultural meaning, as derived from musical experiences. This model, based on the concept of the ‘assemblage’, allows for an in-depth consideration of the abstract topologies of external references in music, and provides a foundation for a taxonomy of the modes of disruption of gestural-sonorous linearity. This is developed in the pursuit of a more dynamic and meaningful conception of the role physical gesture plays in the acquisition of knowledge and meaning in music.</p>

Discontinuity: A compositional approach to the dynamic decoupling of gesture and sound in live performance

<p>The gestural-sonorous object, as described by Rolf Inge Godøy, has experienced a gradual aesthetic splitting in New Music practices. The notion that physical gesture relates to sounding result in a linear, cause-and-effect fashion can no longer be taken as a pre-condition in the study of compositional thought, as New Complexity conceives of ever more diverse modes of instrumentally focussed sound production, while the New Discipline eschews musical tropes altogether. This thesis formulates a new model of information flow in performance, to facilitate an understanding of the role physical gesture plays in the interpretative processes involved in the creation of bodily and cultural meaning, as derived from musical experiences. This model, based on the concept of the ‘assemblage’, allows for an in-depth consideration of the abstract topologies of external references in music, and provides a foundation for a taxonomy of the modes of disruption of gestural-sonorous linearity. This is developed in the pursuit of a more dynamic and meaningful conception of the role physical gesture plays in the acquisition of knowledge and meaning in music.</p>

Effect of Continuous Nursing on Pain and Quality of Life in Patients with Rheumatoid Arthritis

Objective: To explore the effectiveness of continuous nursing in the treatment of patients with rheumatoid arthritis for relieving pain and improving the quality of life of patients. Methods: A total of 80 patients with rheumatoid arthritis were treated in our department from January to August 2021. All patients were treated with continuous nursing, and their quality of life and pain related content were evaluated before admission examination, and their quality of life and pain after discharge were evaluated. Results: The pain degree of patients before continuous nursing intervention was 3.26 ± 0.12, and the pain degree score after nursing was 1.22 ± 0.23, t = 70.3344, P < 0.05. The difference is obvious and comparable; The scores of emotional function, role physical, social function, physical pain, physiological function, mental health, life vitality and overall health of patients before continuous nursing intervention were 71.33 ± 1.23, 72.12 ± 1.36, 71.56 ± 1.42, 73.25 ± 2.01, 74.36 ± 0.96, 73.12 ± 2.45, 72.98 ± 1.63 and 73.56 ± 1.26 respectively, and the scores of emotional function, role physical, social function, body pain, physiological function, mental health, life vitality and overall health were 91.66 ± 1.03, 93.23 ± 1.36, 92.69 ± 1.06, 93.69 ± 1.47, 92.98 ± 1.69, 95.36 ± 1.23, 94.01 ± 1.66 and 94.06 ± 1.69 respectively, P < 0.05. The differences are comparable. Conclusion: Through continuous nursing intervention, after rheumatoid patients are discharged from hospital, the degree of pain of patients is significantly reduced, and the quality of life is significantly improved. Patients can actively integrate into social life and maintain a good attitude.

Quality of life: modified triple-branched stent graft implantation versus frozen elephant trunk technique

Objective To compare the effects of modified triple-branched stent implantation and frozen elephant trunk technique on the quality of life (QoL) of acute Stanford Type A aortic dissection (AAAD) patients at different follow-up times. Methods Data from 175 AAAD survivors was collected which were divided into two groups according to different surgical techniques: (group A): modified triple-branched stent graft implantation; (group B): frozen elephant trunk. The SF-36 were used to assess the QoL at discharge (AD), the third postoperative month (POM3), and the twelfth postoperative month (POM12). Results (1) The total scores at each time of both groups showed lower than the normal level; Group A scored higher than group B at some time points in terms of some items (role physical, role emotion and mental health; all P = 0.000), and some items at POM3 or POM12 scored higher than at discharge (role physical, social function; both P = 0.000). (2) There were less patients with heavy self-perceived burden in group A than group B at discharge (P = 0.032) and patients with heavy self-perceived burden decreased over time. (3) Young postoperative AAD patients (P = 0.002) in group B (P = 0.005) with heavy self-perceived burden (P = 0.000), acute renal failure (P = 0.008), long LOS (P = 0.026) and blood loss (> 1000 mL/24 h) (P = 0.039) seemed to get a worse QoL. Conclusion The impact on QoL of the modified triple-branched stent graft implantation technique seemed to be better than those of frozen elephant trunk surgery in role physical, role emotion and mental health.

Quality of Life: Modified Triple-branched Stent Graft Implantation Versus Frozen Elephant Trunk Technique

Objective: To compare the effects of modified triple-branched stent implantation and frozen elephant trunk technique on the quality of life (QoL) of acute Stanford Type A aortic dissection (AAAD) patients at different follow-up times.Methods: Data from 175 AAAD survivors was collected which were divided into two groups according to different surgical techniques: (group A): modified triple-branched stent graft implantation; (group B): frozen elephant trunk. The SF-36 were used to assess the QoL at discharge(AD), the third postoperative month (POM3), and the twelfth postoperative month (POM12).Results: (1)The total scores at each time of both groups showed lower than the normal level; Group A scored higher than group B at some time points in terms of some items (role physical, role emotion and mental health; all P=0.000), and some items at POM3 or POM12 scored higher than at discharge (role physical, social function; both P=0.000). (2) There were less patients with heavy self-perceived burden in group A than group B at discharge (P=0.032) and patients with heavy self-perceived burden decreased over time. (3) Young postoperative AAD patients (P=0.002) in group B (P=0.005) with heavy self-perceived burden (P=0.000) , acute renal failure (P=0.008) , long LOS (P=0.026) and blood loss（> 1000 mL / 24h）(P=0.039) seemed to get a worse QoL. Conclusion: The impact on QoL of the modified triple-branched stent graft implantation technique seemed to be better than those of frozen elephant trunk surgery in role physical, role emotion and mental health.

Post-surgery Quality of Life in Patients with Acromegaly Using SF36 Quality of Life Questionnaire-prospective Study

Introduction: Acromegaly is chronic progressive disease with multisystem involvement characterised by an excess secretion of growth hormone and increased circulating insulin like growth factor 1 concentration.Aims and Objectives: To assess surgical outcome of acromegaly patients at tertiary care institute using SF 36 quality of life questionnaire. SF-36 scores comprise 3 components: the physical component summary (PCS), the mental component summary (MCS) and role-social component summary (RCS).30 acromegaly patients admitted in Guwahati medical college were enrolled in study and followed up post operatively for surgical remission. All participants completed the SF-36 preoperatively, 1 year and 2 years postoperatively.Material and Method: Out of 30 patients 6 patients had surgical remission post operatively on the basis of postoperative glucose suppressed GH Level done after 12 weeks. Preoperatively subscale scores (physical functioning, role physical, general health) which were below the set standards for the normal population show significant postoperative improvements along with mental health (MH) scores. Similarly, PCS, MCS and RCS scores changed significantly after surgery. We also compared the QOL of 6 patients whose peak GH level was < 0.4 µg/L during postoperative oral glucose tolerance testing with those patients whose nadir GH level was ≥ 0.4 µg/L. There was significant difference between partial and complete remission group in subscale score role physical, social function and mental health. Similarly, PCS and RCS score significantly different in partial and complete remission group than MCS score.Conclusions: QOL is considerably reduced in patients with acromegaly compared to general population which improves significantly after surgical treatment. Patients achieving the new remission criteria had significant improvement in physical and social components than those who did not.

Womens health-related quality of life substantially improves with tailored cardiac rehabilitation: a systematic review and meta-analysis

Funding Acknowledgements Type of funding sources: None. Background Women have poorer outcomes from coronary heart disease (CHD) compared to men and participation in exercise-based cardiac rehabilitation (EBCR) offers an opportunity for improvement. However, synthesised evidence for women-specific patient-reported outcomes are often lacking. We aimed to synthesise HRQL outcomes from EBCR in women with CHD. Methods Four electronic databases (PUBMED, CINAHL, SCOPUS and Cochrane) were searched for studies reporting HRQL using validated measures in women attending EBCR. Two reviewers independently screened papers and extracted data. Random effects model (RevMan v5.4) was used for analysis. Results Eleven studies (1292 women participants) were included: six observational, three randomised controlled trials, and two quasi-experimental design. Seven studies were included in the meta-analyses. EBCR participation was associated with HRQL benefits in several domains of the Short-Form (SF-12 or 36). Improvements were greatest in Role Physical (MD 19.09 95% CI 2.37, 35.81), Physical Functioning (MD 10.43, 95% CI 2.60, 18.27) and Vitality (MD 9.59, 95% CI 0.31, 18.86). When tailored components were added to traditional EBCR, gains in HRQL were also observed, specifically in Bodily Pain (MD 9.82, 95% CI 4.43, 15.21), Role Physical (MD 8.48, 95% CI 1.31, 9.97), Vitality (MD 8.17, 95% CI 3.79, 12.55), General Health (MD 5.64, 95% CI 1.31, 9.97), and Physical Function (MD 5.61, 95% CI 0.83, 10.40) domains. Conclusion Women attending EBCR achieve clinically meaningful improvements in multiple areas of HRQL, and additional benefits were seen when strategies tailored to their needs and preferences were included. Future research should focus on promoting EBCR uptake in women.

Impact of urate-lowering therapy on quality of life indicators in patients with gout

Gout can have a significant impact on the quality of life (QoL) of patients.Objective: to assess the dynamics of QoL indicators and the possibility of achieving the target level of uric acid (UA) in patients with gout on febuxostat therapy, with ineffectiveness and / or contraindications to the allopurinol administration.Patients and methods. The prospective, single-center study included 80 patients with gout. The follow-up period was at least 6 months of allopurinol or febuxostat (Azurix®) therapy in doses required to achieve the target UA level. When urate-lowering therapy was initiated, allopurinol 100 mg per day was prescribed, followed by dose titration (up to maximum of 900 mg per day) until the target UA level was reached (<360 μmol/L). Patients with ineffectiveness of allopurinol and / or adverse reactions (ADRs) were transferred to febuxostat 80–120 mg per day. To prevent arthritis attacks, all patients received low doses of non-steroidal anti-inflammatory drugs or colchicine 0.5 mg per day or glucocorticoids 7,5 mg per day (in prednisolone equivqlent). At the first and last visits, patients on febuxostat completed the SF-36 questionnaire.Results and discussion. After 6 months of follow-up, 70 (88%) patients received urate-lowering therapy, of whom 51 (73%) reached the target UA level. Allopurinol dosage titration required 26 patients, of whom 14 (54%) achieved the treatment goal. Due to the ineffectiveness of allopurinol, 32 patients were switched to febuxostat, which allowed to achieve normouricemia in 69% of cases. Fifteen (68%) of 22 patients who were initiated with febuxostat due to ADRs to allopurinol also achieved the target UA level. Patients who received febuxostat and reached the target UA level improved QoL indicators: role-physical functioning, bodily pain, general health, vitality and general physical well-being (p<0.05 in all cases). Patients who did not reach the target UA level on febuxostat therapy improved such indicators as physical functioning, role-physical functioning, and bodily pain (p<0.05 in all cases). High compliance was observed in 63% of patients, treated with febuxostat and in 36% of patients, treated with allopurinol.Conclusion. In patients with ineffectiveness or intolerance to allopurinol, in 69% of cases febuxostat allows to achieve the target UA level and improving QoL and complience.

Technical Review of The Role Physical Conditions in Football

Football requires good physical condition in playing and competing. There are four phases in football training, namely physical, technical, tactical and mental. This study discusses the physical conditions required in the sport of football and was analyzed using the review method against references published online, related to physical conditions. In this research, it shows that the physical components in football are very influential in the game. Limited this study does not analyze matches. Research related to physical components has been widely used such as strength, flexibility, speed, endurance and anthopometric conditions, namely arm length, leg length.

Treatment Outcomes in Aspirin-Exacerbated Respiratory Disease Based on the 12-Item Short Form Survey

Background Aspirin-exacerbated respiratory disease (AERD) is optimally managed by endoscopic sinus surgery (ESS) followed by aspirin therapy after desensitization (ATAD). Most AERD quality of life (QOL) studies use the 22-item Sinonasal Outcomes Test (SNOT-22), which focuses predominantly on sinonasal outcomes. Objective This study seeks to assess QOL outcomes in AERD patients after ESS and ATAD via the 12-item Short Form Survey (SF-12), a well-validated QOL measure for general health status of chronic conditions. Methods Retrospective review of 112 AERD patients who underwent ESS followed by ATAD at our institution between 2016 and 2019. SF-12 was collected preoperatively, postoperatively/pre-AD, and serially post-AD (1–3, 4–6, 7–12, and >12 months). Optum® PRO CoRE software was used to compare data to national norms. ANOVA was performed comparing physical component summary (PCS), mental component summary (MCS) and eight health domains (physical functioning, role physical, general health, bodily pain, vitality, social functioning, role emotional, and mental health). Results AERD patients showed improvement in PCS scores across all timepoints after ESS and ATAD (p = 0.004). When stratified by gender, women demonstrated an improvement in PCS scores (p = 0.004). Within the domains, there were significant improvements in social functioning (SF), role physical (RP), and bodily pain (BP) at all timepoints (SF: p = 0.006; RP: p = 0.005; BP: p < 0.001). Conclusions AERD patients undergoing ESS and ATAD show improvement in physical QOL and 3 of the 8 health domains as measured by the SF-12. Future studies can use the SF-12 to study the impact of AERD treatment versus other chronic diseases and health demographics.