scholarly journals Hydrocephalus Surgery in Touba City (Senegal): 0% infection Preliminary study about 20 cases

2021 ◽  
Vol 12 (2) ◽  
pp. 315-323
Author(s):  
Wague Daouda ◽  
CISSE Mouhamet Abdoulaye ◽  
Sarr Ndeye Ndoumbe ◽  
Thioub Mbaye ◽  
Mbaye Maguette ◽  
...  
Keyword(s):  
Antibiotic Therapy ◽  
Ventriculoperitoneal Shunt ◽  
Standard Technique ◽  
Shunt Insertion ◽  
Brain Ct Scan ◽  
Preliminary Study ◽  
Common Sign ◽  
One Year ◽  
Consultation Time

Introduction: Infection is the most common complication encountered after ventriculoperitoneal shunt. The AIMS of this study is to evaluate the effectiveness of antibiotic therapy with protocol in the prevention of post-operative infections after ventriculoperitoneal shunt in our city. Patients and methods: We retrospectively study 20 hydrocephalus cases in one year. They were operated through the classic VP Shunt insertion technique and with the protocol adopted for shunt implantation. They received antibiotic therapy for ten days. Results: In one year we operated 95 patients,20 (21%) cases were hydrocephalus. There were 7 males et 13 females (ratio:0,53) . The age of patients ranged from 15 days to 12 years and the average age was 13,5 months. The average consultation time was 5,6 weeks. Clinically the most common sign were anterior fontanelle tense (100%) , macrocrania (60%) ,vomiting (80%) and sunset eye sign (80%) . Brain CT-scan was performed in all patient,66% of patients had Transfontanelle Ultrasonography and anyone hadn’t performed MRI. All cases underwent surgical treatment. only ventriculoperitoneal shunt was performed and the standard technique protocol to minimize infection was done during surgery. All of them received ceftriaxone 100mg/kg/day for five days then oral relay by thiamphenicol 50mg/Kg/day for five days. The follow up was good no infection was found (0%). Conclusion: Establishing an aseptic protocol for the shunt is essential to reduce the rate of postoperative infections. This result becomes better when we make a combination of antibiotic therapy and protocol. We can achieve infection rates to zero or less than 1% in case of association

scholarly journals Efficacy of stereotactic aspiration in deep-seated and eloquent-region intracranial pyogenic abscesses

2008 ◽  
Vol 24 (6) ◽  
pp. E13 ◽  
Author(s):  
Xavier G. Kocherry ◽  
Thimappa Hegde ◽  
Kolluri V. R. Sastry ◽  
Aaron Mohanty
Keyword(s):  
Antibiotic Therapy ◽  
Complete Resolution ◽  
Early Recurrence ◽  
Shunt Insertion ◽  
Stereotactic Aspiration ◽  
Source Of Infection ◽  
Cerebral Parenchyma ◽  
Eloquent Cortex ◽  
Repeated Aspiration

Object Intracranial abscesses located deep in the cerebral parenchyma and in eloquent regions are often difficult to manage surgically. The authors have attempted to analyze the efficacy of stereotactic aspiration in the management of these abscesses. Methods Cases involving 22 patients (including 9 children) with deep-seated and/or eloquent-region intracranial abscesses who underwent CT- or MR imaging–guided stereotactic aspiration between January 1995 and July 2001 were analyzed. Results A definite source of infection could be identified only in 9 of the cases. In 18 patients, the abscess was deep seated, whereas in the rest it was located in the eloquent cortex. Five patients had abscesses located in multiple sites. In 17 patients only 1 aspiration was required; in 5 others subsequent procedures were required. In the initial postaspiration CT, minor hemorrhage was noted in 3 patients not requiring further intervention. Antibiotics were administered for a period varying from 4 to 8 weeks following aspiration. An early recurrence (within 2 weeks of initial aspiration) was evident in 5 patients. All recurrent abscesses were reaspirated. In 2 patients new abscesses developed while the patients were still receiving antibiotic therapy. There were no late recurrences. In 1 patient ventriculitis developed, with subsequent hydrocephalus requiring a shunt insertion. Follow-up CT scans showed complete resolution of the abscess in all patients. There were no deaths. Conclusions Stereotactic aspiration is a useful management option for abscesses located in eloquent or inaccessible regions. Repeated aspiration should be considered in patients in whom the initial aspiration proves ineffective or partially effective. Complete resolution may require repeated stereotactic aspirations and continued antibiotic therapy.

Dependency between vitamin D3 and serum titers of the thyroid autoantibodies in smoking cigarettes patients with Graves' disease - one year follow-up - preliminary study

2018 ◽  
Author(s):  
Maria Teresa Plazinska ◽  
Agata Czarnywojtek ◽  
Malgorzata Zgorzalewicz-Stachowiak ◽  
Nadia Sawicka-Gutaj ◽  
Barbara Czarnocka ◽  
...  
Keyword(s):  
Vitamin D3 ◽  
Graves Disease ◽  
Thyroid Autoantibodies ◽  
Preliminary Study ◽  
One Year

scholarly journals Steroid Hormones and Homocysteine in the Outcome of Patients With Normal Pressure Hydrocephalus

2015 ◽  
pp. S227-S236 ◽  
Author(s):  
L. SOSVOROVA ◽  
M. MOHAPL ◽  
M. HILL ◽  
L. STARKA ◽  
M. BICIKOVA ◽  
...  
Keyword(s):  
Gas Chromatography ◽  
Cerebrospinal Fluid ◽  
Steroid Hormones ◽  
Normal Pressure Hydrocephalus ◽  
Ventriculoperitoneal Shunt ◽  
Plasma Levels ◽  
Normal Pressure ◽  
Plasma Homocysteine ◽  
Shunt Insertion

Normal pressure hydrocephalus (NPH) is one of a few treatable conditions of cognitive decline affecting predominately elderly people. Treatment, commonly based on the ventriculoperitoneal shunt insertion, leads to a partial or complete correction of patient's state, although its effect does not unfortunately always last. The aim of our study was to observe the changes of homocysteine and selected steroids and neurosteroids and follow-up the patients with respect to the duration of the NPH-related dementia improvement. The cerebrospinal fluid and plasma levels of cortisol, cortisone, dehydroepiandrosterone (DHEA), 7α-hydroxy-DHEA, 7β-hydroxy-DHEA, 7-oxo-DHEA, 16α-hydroxy-DHEA (all LC-MS/MS), DHEA-sulphate (DHEAS) (radioimmunoassay) and homocysteine (gas chromatography) were determined in NPH-diagnosed subjects before, during and 6, 12 and 24 months after shunt insertion. The cognitive functions ameliorated after shunt insertion and remain improved within 2 years. Changes in cerebrospinal fluid DHEAS, DHEA and its ratio, cortisone/cortisol and 16α-hydroxy-DHEA and plasma DHEAS, 7β-hydroxy-DHEA, cortisone/cortisol and homocysteine were found. Mentioned changes may contribute to the clarification of NPH pathogenesis. Altered neurosteroids levels are possible indicators to be utilized in the follow-up of NPH subjects. Moreover, plasma homocysteine may serve as an early indicator of NPH-related dementia.

Evaluation of an Experimental Treatment for Problem Drivers

1978 ◽  
Vol 20 (4) ◽  
pp. 489-493 ◽  
Author(s):  
Jon C. Prothero
Keyword(s):  
Experimental Treatment ◽  
Control Group ◽  
Record Data ◽  
Preliminary Study ◽  
New Treatment ◽  
One Year ◽  
Hearing Officers ◽  
Experimental Group

This preliminary study compared the effectiveness of a new treatment for problem drivers with the National Safety Council's Defensive Driving Course (DDC) and a control group. Hearing officers from four large Florida cities randomly assigned 432 problem drivers, whose licenses had been suspended, to three groups. Safety officers from each of the four locations taught both the experimental course and the DDC. Pretests and posttests on driving knowlege and attitudes were administered to the three groups. Driving record data of the 358 subjects who completed treatment were used to help identify long-term effectiveness of the treatments. Although there was no significant improvements between the groups in driving knowledge or in attitudes after treatment, the experimental group had a greater reduction than the DDC group and a significantly greater reduction than the control group in traffic law violations and collisions during a one year follow-up period. A larger investigation of the effectiveness of the experimental course is recommended.

scholarly journals Temporary Mental Nerve Paresthesia Originating from Periapical Infection

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Ozgur Genc Sen ◽  
Volkan Kaplan
Keyword(s):  
Antibiotic Therapy ◽  
Root Canal ◽  
Complete Healing ◽  
Periapical Lesion ◽  
Mental Nerve ◽  
Local Factors ◽  
Endodontic Infection ◽  
Dental Origin ◽  
One Year

Many systemic and local factors can cause paresthesia, and it is rarely caused by infections of dental origin. This report presents a case of mental nerve paresthesia caused by endodontic infection of a mandibular left second premolar. Resolution of the paresthesia began two weeks after conventional root canal treatment associated with antibiotic therapy and was completed in eight weeks. One year follow-up radiograph indicated complete healing of the radiolucent periapical lesion. The tooth was asymptomatic and functional.

Evaluation of Diagnostic Strategies for Fetal Skeletal Dysplasia Using Ultrasound Scan and Gene Testing: A Preliminary Study in Wu Han, China

2021 ◽  
Author(s):  
Wanlu Liu ◽  
Jing Cao ◽  
Xinwei Shi ◽  
Yuqi Li ◽  
Fuyuan Qiao ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Skeletal Dysplasia ◽  
Genetic Diagnosis ◽  
Gene Variants ◽  
Sonographic Examination ◽  
Gene Testing ◽  
Whole Exome ◽  
Preliminary Study ◽  
One Year

Abstract Objective: The aim of this study was to deliver prenatal diagnosis through sonographic examination and gene variation testing, and to evaluate the outcome of applied strategies in prenatal diagnosisMethods: From September 2015 to April 2021, the study investigated 24 cases with suspected short long bones, which were obtained from the prenatal diagnosis center of Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology. The likely pathogenic gene variants were analyzed by multiple approaches (including karyotype analysis, copy number variations and whole exome sequencing) and further determined with the accuracy of the prenatal diagnosis for fetal skeletal dysplasia through one year follow-up survey. Results: ① We found fetal skeletal dysplasia or malformation in 8 cases (account for 33.3%) before 24 weeks of gestation and in the rest cases after 30 weeks of gestation. ② Out of 24 cases, likely pathogenic gene variants in FGFR3, FBN2, COL1A2, CUL7 and DYNC2H1 were detected for 6 cases; genetic variants in FGFR3, IMPAD1 and GORAB as possibly lethal mutations were identified in other 6 cases; and gene variants in WNT1, FBN1, OBSL1, COL1A1, DYNC2H1 and NEK1, known as Variant of Undetermined Significance (VUS), were found in 4 cases. The rest 8 cases showed undetectable mutation in the whole exome sequencing (WES) analysis.③ A genetic diagnosis determined 12 different skeletal dysplasia genotypes in 14/24 (58.3%) cases. The other 10 cases with wild type gene (41.7%) were normal and well developed in one-year follow-up survey after study.Conclusion: Features of fatal skeletal dysplasia can be identified in utero using fetal ultrasound and gene testing. Sonographic examination combining with genetic diagnosis showed advance in prenatal diagnosis in the preliminary study and the applied strategy could be used to help with improving the accuracy of prenatal diagnosis for fetal skeletal dysplasia.

scholarly journals Endoscopic Third Ventriculostomy (ETV) versus Ventriculoperitoneal Shunt (VPS) for pediatric hydrocephalus: a meta-analysis

2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Mohamad Saekhu ◽  
Eko Suryo Pujiastono ◽  
Fabianto Santoso
Keyword(s):  
Ventriculoperitoneal Shunt ◽  
Endoscopic Third Ventriculostomy ◽  
Meta Analysis ◽  
Standard Technique ◽  
Fixed Effect Model ◽  
Third Ventriculostomy ◽  
Pediatric Hydrocephalus ◽  
Effect Model ◽  
Surgical Failure ◽  
One Year

Background:Using Endoscopic Third Ventriculostomy (ETV) or Ventriculoperitoneal Shunt (VPS) as standard technique of cerebrospinal fluid (CSF) diversion has been a debatable issue. To date, a meta-analysis on the best treatment for pediatric hydrocephalus is yet to be done. ETV has been reported to have successful outcomes in many studies. The objective of this meta-analysis is to know the effectiveness of ETV compared to VPS in pediatric hydrocephalus.Methods:This study used electronic articles published in PubMed, EBSCO, and Google Scholar from January 1990 until January 2017. Articles included were full-text observational study or randomized control trial in Bahasa or English. Surgical failure was compared for this meta-analysis. Statistical analysis was done by using Review Manager 5.Results:Five articles met our inclusion and exclusion criteria. The pooled risk ratio (ETV vs. VPS) of surgical failure was 0.95 [0.76, 1.19] for fixed effect model. This analysis had no or little heterogeneity (I2 = 18%; X2=0.25).Conclusion:In one year follow up, there is no superiority between both procedures in surgical failure. Limited studies have been conducted to compare the effectiveness of ETV compared with VPS for pediatric hydrocephalus management. Further studies comparing both treatments are required to know the best management for pediatric hydrocephalus.Keywords: ETV, VPS, pediatric hydrocephalus, meta-analysis

scholarly journals One-year follow up of auditory performance in post-lingually deafened adults implanted with the Neurelec Digisonic® SP/Saphyr® Neo cochlear implant system

2015 ◽  
Vol 5 (2) ◽  
Author(s):  
Déborah Borger ◽  
Geneviève Lina-Granade ◽  
Stéphanie Verneyre ◽  
Hung Thai-Van ◽  
Sonia Saaï ◽  
...  
Keyword(s):  
Speech Perception ◽  
Cochlear Implant ◽  
Auditory Performance ◽  
Preliminary Study ◽  
One Year ◽  
Implant System ◽  
Technological Improvements ◽  
Sound Processor ◽  
Made In

This study aimed to quantify outcomes in a group of patients who were implanted with an Oticon Medical Neurelec (Vallauris, France) cochlear implant system, the Digisonic® SP/Saphyr® Neo. Ten participants took part in this preliminary study. Their speech perception capacities were evaluated at 3, 6, and 12-months after cochlear implant activation and compared to pre-implantation scores and to scores observed with former versions of the sound processor. Compared to former versions of the sound processor, patients using the Saphyr® Neo processor obtained better speech perception scores for sentences in silence at each tests session (3 months: 79%, 6 months: 82% and 12 months: 94%) compared to Digisonic® users (respectively: 58%, 69% and 75%) and Convex sound processor users (resp. 39%, 59% and 51%). These observations confirm that the technological improvements made in the Saphyr® Neo sound processor coupled with the Digisonic® implant, provided quantifiable benefits in speech perception in Quiet compared to former versions of the processor Convex and Digisonic® SP.

Globular subdural hematoma in a shunt-treated infant

2010 ◽  
Vol 5 (2) ◽  
pp. 210-212 ◽  
Author(s):  
Takahiro Murata ◽  
Hiroaki Shigeta ◽  
Tetsuyoshi Horiuchi ◽  
Keiichi Sakai ◽  
Kazuhiro Hongo
Keyword(s):  
Mr Imaging ◽  
Ventriculoperitoneal Shunt ◽  
Subdural Hematoma ◽  
Resonance Imaging ◽  
Shunt Insertion ◽  
Outer Membranes ◽  
History Of ◽  
Craniocerebral Disproportion ◽  
Valve Pressure

Subdural hematoma (SDH) is a well-known sequela of ventriculoperitoneal shunt insertion for hydrocephalus, usually spreads out over the cerebral convexity, and appears as a crescent-shaped lesion on imaging. The authors report the rare case of an infant with a globular SDH, which MR imaging revealed as a round mass lesion. A 13-month-old girl with a history of severe congenital hydrocephalus associated with myeloschisis underwent ventriculoperitoneal shunt placement after repair of myeloschisis and developed convulsive seizure. Magnetic resonance imaging showed a large subdural round mass with a lesion like a pedestal in the left parietal region, suggesting a globular SDH surrounded by a thin cerebral mantle. Because of the seizures and because the hematoma did not respond to a change in valve pressure, the patient underwent a craniotomy to remove the hematoma and to resect the thick outer membranes of multiple layers. Postoperative MR imaging demonstrated the disappearance of the SDH, and no additional shunt complication was observed during a long follow-up period. To the authors' knowledge, this is the first report of a patient with globular SDH published in the literature. The authors postulate that the globular SDH was caused by the thin cerebral mantle associated with severe craniocerebral disproportion, and they discuss the possible mechanisms for this unique formation.

Sign in / Sign up

Export Citation Format

Share Document