scholarly journals Iodine Status of School Age Children 6-12 Years in Umuahia South LGA of Abia State, Nigeria

Author(s):  
A.D. Oguizu ◽  
J.O. Nwagwu

Background: Iodine deficiency disorders have continued to be a significant health problem in some Nigerian communities despite universal salt iodization. Objective: This study was designed to assess the iodine status of school age children (6-12 years) in Umuahia South LGA of Abia State, Nigeria. Methods: A total of 414 school children were studied. Urine samples were obtained from 84 school children, 30 males and 54 females. The background and socio-economic information, food habit and dietary intake of the respondents were determined using validated questionnaires. Urinary iodine concentration analysis, using Sandell-Kolthoff reaction was used to determine the iodine status of the children. Chi-square was used to determine the relationship between urinary iodine status of the children and the socio-economic characteristics of their parents. Results: More than half (58.7%) of the children were females while 40.5% were males. About a quarter of the children (40.1%) were 9-10 years, 23.4% were 11-12 years while 36.5% were 6-8 years. Most of the respondents (72.2%) were aware of iodized salt; 14.3% heard about iodized salt from friends, 41.8% heard from the media while 13% heard about iodized salt from the market. Majority of the respondents (94.4%) claimed they consume iodized salt while 4.9% said they use salts that were measured in cups which was not iodized salt. The study revealed that 54.3% of the school children had optimal iodine status while 35.7% had mild iodine deficiency which was higher in males (46.7%) than in females (29.6%). About 5.6% of the respondents had grade 1 goiter. There was a significant association (p< 0.05) between urinary iodine status of the school children and educational status of their fathers’, mothers’, parents’ occupation and income level of fathers. Conclusion: Nutrition education should be aimed at mothers, caregivers, and school children to promote consumption of iodine rich foods.

2015 ◽  
Vol 4 (2) ◽  
pp. 42-46 ◽  
Author(s):  
Fazli Subhan ◽  
Muhammad Jahangir ◽  
Saira Saira ◽  
Rehman Mehmood Khattak ◽  
Muhammad Shahab ◽  
...  

Pakistan is considered to be one of the most severely iodine deficient countries in the region. A decade earlier, 70% of the population was estimated to be at risk of iodine deficiency. However, the recent use of iodized salt has reduced the intensity of the problem. Earlier studies regarding iodine deficiency in Pakistan were restricted to the northern mountainous regions, but have now been extended to the sub-Himalaya areas and the plains of Punjab. The aim of the present study was to investigate the prevalence of goiter and iodine status among school children in district Kohat, Pakistan. The 30 cluster approach was adopted for the study. From each cluster, 40 samples were collected from school going children. The palpation method was used to measure goiter grade, whereas, for urinary iodine estimation, the wet digestion method was used. The prevalence of goiter in the district was found to be 35% (37.16% in boys and 33% in girls). The median urinary iodine concentration was found to be 56±31.19?g/L. Estimation of iodine content in salt illustrated that 56.8% people were consuming non-iodized salt and 43.5% were using iodized salt. The current study suggests a severe iodine deficiency in school children of district Kohat and regular iodine supplementation is required on an instant basis.South East Asia Journal of Public Health Vol.4(2) 2014: 42-46


2017 ◽  
Vol 39 (1) ◽  
pp. 49
Author(s):  
Djoko Kartono ◽  
Atmarita Atmarita ◽  
Abas B Jahari ◽  
Soekirman Soekirman ◽  
Doddy Izwardy

Iodine Deficiency Disorders (IDD) are the leading cause of goiter, cretinism, developmental delays and other health problems. Iodine deficiency is an important public health issue as it is a preventable cause of intellectual disability. While elimination of iodine deficiency is imperative, it should be noted that excessive intake of iodine can also lead to adverse health effects. This paper analyzed the iodine status using median urinary iodine concentration (MUIC) of school age children (SAC), women of reproductive age (WRA), and pregnant women (PW) who live in the same household from Riskesdas 2013. The total number of households included in the analysis was 13,811 households, from which 6,149 SAC (aged 6 – 12 years), 13,218 WRA (aged 15-49 years), and 578 PW (aged 15-49 years) were enumerated. The national MUIC of SAC, WRA and PWwas  in the normal range indicated that  the iodine status was adequate using WHO epidemiological criteria. Iodine status in some sub-populations indicated deficiency, however, in terms of geographic characteristics people who live in the urban has better iodine status compared to rural areas. Similarly, populations in richer economic quintiles had better iodine status. Only pregnant women in the 1st and 2nd quintile were deficient. Almost all regions in Indonesia showed the MUIC was in the normal adequate range, except NTT-NTB, Maluku-Papua, and East Java for pregnant women who tend to have lower MUIC (<150 µg/L). The status of iodized salt at the household was detected using both Rapid Test Kit/RTK as well as Titration. The result demonstrated a strong association between salt iodine level and iodine status. The MUIC for all three groups were lower when the iodine level in salt was lower, then increased when the levels of iodine content in salt increased. The iodine status of pregnant women consuming non-iodized salt was inadequate. The detrimental effect of iodine deficiency on the mental and physical development of children as well as on the women of reproductive age has been recognized. Indonesia still needs the salt iodization program to keep the iodine status in the normal range. In particular coverage with adequately iodized salt needs to be improved in order to improve the iodine status of pregnant women. For the prevention of Iodine disorders (insufficient), monitoring should be undertaken in regular basis to assess the MUIC, especially for pregnant women.


2013 ◽  
Vol 1 (1) ◽  
pp. 38-41
Author(s):  
AK Nepal ◽  
S Gautam ◽  
S Khatiwada ◽  
PR Shakya ◽  
B Gelal ◽  
...  

Background: Iodine deficiency remains a significant health problem in developing countries, including Nepal.   Objective: This study was conducted to measure the iodine status of school children in two districts Dhankuta and Tehrathum of Eastern Nepal by estimating median urinary iodine concentration (UIC) as a population parameter in the school children. Materials and Methods: This cross-sectional study was conducted from August 2010 to July 2011 in school children (6-12 years of age) of two hilly districts of Eastern Nepal, Dhankuta and Tehrathum. A total of 154 school age children from the two districts were chosen for the study after obtaining written consent from their guardians and school authority. UIC was estimated in these school children by ammonium persulphate digestion microplate method. Results: Among the school age children selected for the study median inter-quartile range (IQR) of urinary iodine in Dhankuta (n=63) and Tehrathum (n=91) districts were 214.04 (126.44; 323.0) μg/L and 252.34 (161.81; 301.63) μg/L. No significant differences were observed between the median UIC of these two districts (p=0.235). Among the school children in Dhankuta districts 2(3.2%) were severely deficient, 4(6.3%) were moderately deficient and 6(9.5%) were mildly deficient. In Tehrathum district 2(2.2%) were moderately deficient and 5(5.5%) were mildly deficient. Conclusion: The present study showed improved iodine status with optimal levels of median urinary iodine concentration in the two districts, Dhankuta and Tehrathum of Eastern Nepal. Regular monitoring of population median urinary iodine concentration is recommended for sustainable optimal iodine nutrition.DOI: http://dx.doi.org/10.3126/stcj.v1i1.7986 Sunsari Technical College Journal Vol.1(1) 2012 38-41


2020 ◽  
Vol 26 (2) ◽  
pp. 63-69
Author(s):  
Scrinic Olesea ◽  
Delia Corina Elena ◽  
Toma Geanina Mirela ◽  
Circo Eduard

Abstract Objective: Assessment of iodine nutritional status in pregnant women in the perimarine area of Romania, a region without iodine deficiency. Adequate iodine intake is the main source for normal thyroid function, ensuring the need for maternal thyroid hormones during pregnancy, but also for the development and growth of children in the fetal and postpartum period. Material and method: Prospective study performed on 74 pregnant women in the first 2 trimesters of pregnancy, originating from the perimarin area. The following indicators of iodine status were analyzed: urinary iodine concentration (UIC), the ratio between urinary iodine concentration and urinary creatinine (UIC/UCr), the prevalence of maternal goiter and the value of neonatal TSH (thyroid stimulating hormone). Results: The mean gestational age was 11 weeks. The ways of iodine intake are: iodized salt - 59.4%, iodized salt and iodine supplements- 23%, only iodine supplements -10.8% and 6.8% consume only non-iodized salt. The median of UIC was 133.03 mcg/l considered insufficient iodine intake (normal in pregnancy UIC >150 mcg/l), but the adjustment of UIC to urinary creatinine reveals a median of 152.83 mcg/g, a value that reflects an adequate iodine intake. The prevalence of goiter was 25.6% characteristic for a moderate iodine deficiency. The prevalence of neonatal TSH >5 mIU/L was registered in 18.8% characteristic of mild iodine deficiency. Conclusions: Monitoring of the iodine nutritional status is recommended for the prevention of disorders due to iodine deficiency under the conditions of universal salt iodization. Perimarine areas considered sufficient in iodine may show variations in iodine status in subpopulations under certain physiological conditions, such as pregnancy. An indicator of iodine status of the population is UIC, but the UIC/UCr ratio may be a more optimal indicator for pregnant women, to avoid possible overestimated results of iodine deficiency in pregnancy.


2019 ◽  
Vol 110 (4) ◽  
pp. 949-958 ◽  
Author(s):  
Molla Mesele Wassie ◽  
Philippa Middleton ◽  
Shao Jia Zhou

ABSTRACT Background Population iodine deficiency is indicated by >3% of the population with newborn thyroid-stimulating hormone (TSH) concentration >5 mIU/L, median urinary iodine concentration (MUIC) <100 µg/L, or >5% prevalence of goiter in school-age children. However, the agreement between these population markers has not been systematically investigated. Objective To assess the agreement between TSH, MUIC, and goiter as markers of population iodine status. Methods We performed a systematic search for studies published on PubMed, Scopus, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Embase, and PsycINFO up to 29 October, 2018. Studies assessing iodine status in the population using the TSH marker and either MUIC or goiter prevalence in school-age children were included. The agreement between markers in classifying iodine status of the population was assessed. The sensitivity and specificity of the TSH marker was determined against MUIC and goiter prevalence as the reference markers. Results Of 17,435 records identified by the search strategy, 57 eligible studies were included in the review. The agreement between markers in classifying the iodine status of populations into the same category was 65% for TSH and MUIC, and 83% for TSH and goiter prevalence. The TSH marker had a sensitivity of 0.75 and specificity of 0.53 when compared with MUIC, and 0.86 and 0.50 when compared with goiter prevalence. Conclusions The TSH marker has a better agreement with goiter prevalence than MUIC when classifying the iodine status of populations. Re-evaluation of the current criteria for classifying the iodine status of populations using the TSH marker is warranted. This systematic review was registered at PROSPERO (http://www.crd.york.ac.uk/prospero/) as CRD42018091247.


Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1404
Author(s):  
Xiaoyun Shan ◽  
Changqing Liu ◽  
Xiaoyan Luo ◽  
Yan Zou ◽  
Lichun Huang ◽  
...  

We evaluated the iodine nutritional status and related factors among school-age children based on the 2016 National Nutrition and Health Surveillance of Children and Lactating Women; 3808 children from Hebei, Guangxi, and Zhejiang province were included in the study. Urinary iodine concentration (UIC), thyroid-stimulating hormone (TSH), body mass index (BMI), vitamin A (VA), and vitamin D (VD) were measured. The abnormal rate of UIC and TSH were assessed. Relationships between UIC/TSH and the possible factors were analyzed. The overall median UIC was 185.14 µg/L, and the median UIC of children aged 8–10 was 164.60 µg/L. Prevalence of iodine deficiency and excess was 13.84% and 14.36%, respectively, and 12.87% of children showed TSH excess. UIC, as well as the abnormal rates of iodine deficiency (ID) and TSH, were significantly different among the three provinces. The median UICs and excess rates increased with age, reaching 211.45 µg/L and 21.35% at age of 14~, while TSH showed the opposite trend. Overweight children tended to have lower UIC and higher TSH. Higher UIC and TSH were found in VA sufficient group (p < 0.01). Further, the VD deficient group had a higher TSH compared to the sufficient group (p < 0.01). Moreover, UI and TSH distribution was obviously different among different vitamin A/D status (p < 0.05). Although the median UIC of school-age children was optimal, there were pockets of inadequate and excessive UI in the three provinces. Compared to the national IDD monitoring results in 2014, the iodine nutritional status of children was greatly improved. Considerations of region, age, BMI, VA, or VD are needed in the future iodine evaluation and surveillance.


2018 ◽  
Vol 48 (6) ◽  
pp. 873-885
Author(s):  
Naima Saeid ◽  
Anass Rami ◽  
Samir Mounach ◽  
Abdeslam Hamrani ◽  
Asmaa El Hamdouchi ◽  
...  

Purpose Iodine deficiency has several adverse effects on human growth and development and it is categorized collectively as iodine deficiency disorders (IDDs). Recent estimations showed that 29.8 per cent of school-age children have insufficient iodine intake. Salt iodization is widely accepted as the best method for increasing iodine intake. In 1995, Morocco adopted the universal salt iodization strategy to reduce iodine deficiency and consequently prevent and control IDDs. This study aims to determine the benefit of this strategy on schoolchildren and adolescent by assessing iodine intake and evaluating iodine deficiency. Design/methodology/approach This transversal study was conducted on 131 children and adolescents. Iodine intake was assessed using a food frequency questionnaire. Iodine status was evaluated on 24-h urine samples and the creatinine excretion was used to validate completeness of urine collection. Findings The medians of urinary iodine excretion and concentration were 77 µg/day and 96 µg/L, respectively. Overall, 72.5 per cent are deficient, so mild and moderate iodine deficiencies were reported in 58 per cent and 14.5 per cent, respectively, and no child exhibited severe deficiency. A significant difference was reported between iodine deficiency and, sex and age; iodine deficiency was more pronounced in boys and children under eight years. In this study, iodine status in deficient children does not change with the consumption pattern of dairy products and eggs, and results showed no significant association (p > 0.05). However, fish consumption was significantly associated to urinary iodine concentration = 100 µg/L (p = 0.044). Average UIC in school-aged children is still inadequate and consumption of foods high in iodine remains very insufficient. Therefore, additional efforts must focus on nutritional education of Moroccan school-aged children. Originality/value In the author’s knowledge, this is the first study evaluating schoolchildren iodine status by 24-h iodine collection; the study reported association of iodine deficiency with dietary habit concerning sources of food rich on iodine.


2018 ◽  
Vol 14 (3) ◽  
pp. 149-155
Author(s):  
Tatiana V. Mokhort ◽  
Sergei V. Petrenko ◽  
Boris Y. Leushev ◽  
Ekaterina V. Fedorenko ◽  
Natalia D. Kolomiets ◽  
...  

Background. Despite the measures taken by the Government of Belarus, the problem of iodine deficiency among the population remains actual. Aims. To determine iodine sufficiency in children and pregnant women living in Belarus. Materials and methods. The study included 873 schoolchildren aged 9–12 years of both sexes, of which 650 children were in regular schools, and the remaining children in boarding schools. A separate group consisted of 700 practically healthy pregnant women (during gestation from 16 to 36 weeks). Questioning, determination of urinary iodine concentration and thyroid volume with ultrasound was carried out. Results. Urine iodine median was 191 µg/L in the 873 children in 16 regions of Belarus. Thyroid volume corresponds to the normative values in children. According to the survey, 81% of households used iodized salt, constantly – 46%. Indicator of iodine sufficiency of 700 pregnant women (median urinary iodine concentration was 121 µg /l) is a non-optimal for this population group. Conclusions. Currently adequate iodine supplementation in school age children has been achieved. The prevalence of thyroid gland diseases caused by iodine deficiency in children decreased significantly. In pregnant women iodine supply is still insufficient.


2009 ◽  
Vol 30 (4) ◽  
pp. 376-408 ◽  
Author(s):  
Michael B. Zimmermann

Abstract Iodine deficiency has multiple adverse effects in humans, termed iodine deficiency disorders, due to inadequate thyroid hormone production. Globally, it is estimated that 2 billion individuals have an insufficient iodine intake, and South Asia and sub-Saharan Africa are particularly affected. However, about 50% of Europe remains mildly iodine deficient, and iodine intakes in other industrialized countries, including the United States and Australia, have fallen in recent years. Iodine deficiency during pregnancy and infancy may impair growth and neurodevelopment of the offspring and increase infant mortality. Deficiency during childhood reduces somatic growth and cognitive and motor function. Assessment methods include urinary iodine concentration, goiter, newborn TSH, and blood thyroglobulin. But assessment of iodine status in pregnancy is difficult, and it remains unclear whether iodine intakes are sufficient in this group, leading to calls for iodine supplementation during pregnancy in several industrialized countries. In most countries, the best strategy to control iodine deficiency in populations is carefully monitored universal salt iodization, one of the most cost-effective ways to contribute to economic and social development. Achieving optimal iodine intakes from iodized salt (in the range of 150–250 μg/d for adults) may minimize the amount of thyroid dysfunction in populations. Ensuring adequate iodine status during parenteral nutrition has become important, particularly in preterm infants, as the use of povidone-iodine disinfectants has declined. Introduction of iodized salt to regions of chronic iodine deficiency may transiently increase the incidence of thyroid disorders, but overall, the relatively small risks of iodine excess are far outweighed by the substantial risks of iodine deficiency.


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