scholarly journals Synthesis, Characterization and Screening of Anti-tubercular activity of 2, 5-Disubstituted-1, 3, 4-Oxadiazole

2013 ◽  
Vol 1 (03) ◽  
pp. 12-19
Author(s):  
Alex Martin
Keyword(s):  
Spectral Analysis ◽  
Carboxylic Acid ◽  
Microwave Irradiation ◽  
Hydrazine Hydrate ◽  
Spectral Data ◽  
Acid Hydrazide ◽  
Mass Spectral Data ◽  
Furoic Acid ◽  
Mass Spectral ◽  
Phosphorous Oxychloride

The synthesis of 2-furyl-5-(substituted)-1,3,4-oxadiazoles was carried out by microwave irradiation of 2-furoic acid and ethanol followed by subsequent hydrazinolysis with hydrazine hydrate. Finally furan-2-acid hydrazide was treated with appropriate carboxylic acid in the presence of phosphorous oxychloride to produce title compounds. The structures of the newly synthesized compounds were established on the basis of spectral analysis such as IR, H1NMR and Mass spectral data. The synthesized compounds were screened for their anti-tubercular activity.

scholarly journals Microwave Assisted Synthesis of New 1-{2, 4-Dihydroxy-5-[5-(aryl)-1-pyridine/pyrimidine-4-carbonyl)-4, 5-dihydro-1H-pyrazol-3-yl]-phenyl}-3-(aryl)-propenones and their Antibacterial Activity

2009 ◽  
Vol 6 (2) ◽  
pp. 323-331
Author(s):  
D. Ashok ◽  
K. Aravind
Keyword(s):  
Antibacterial Activity ◽  
Microwave Irradiation ◽  
Spectral Data ◽  
Acid Hydrazide ◽  
Microwave Assisted Synthesis ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
H Nmr ◽  
Microwave Assisted ◽  
C Nmr

A series of 1-{2, 4-dihydroxy-5-[5-(aryl)-1-pyridine/pyrimidine-4-carbonyl)-4, 5-dihydro-1H-pyrazol-3-yl]-phenyl}-3-(aryl)-propenones (2a-h) have been synthesized from 1-[2,4-dihydroxy-5-(aryl acryloyl)phenyl]-aryl propenones(1a-h)by Micheal addition with isoniazide/pyrazinic acid hydrazide under microwave irradiation and classical heating. The synthesized compounds were characterized by IR,1H-NMR,13C-NMR and Mass spectral data. All the compounds were screened for their Antibacterial activity.

Phenolic Analogs of Amino Carboxylic-Acid Ligands for Tc-99m. 1. Synthesis and Characterization of N,N'-Ethylenebis[2-(-O-Hydroxyphenyl)Glycines] (Ehpg)

1987 ◽  
Vol 40 (10) ◽  
pp. 1695 ◽  
Author(s):  
JG Wilson
Keyword(s):  
Carboxylic Acid ◽  
Spectral Data ◽  
Dimethyl Ester ◽  
Synthesis And Characterization ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Amino Carboxylic Acid

Nine N,N'- ethylenebis [2-(o- hydroxyphenyl ) glycines ] ( ehpg ) have been prepared and characterized by conversion into their dimethyl ester dihydrochlorides. Their i.r ., 1H n.m.r. and f.a.b. mass spectral data are presented and discussed.

scholarly journals PHYTOCHEMICAL STUDY OF THE ARIAL PARTS OF Cleome rutidosperma DC PLANT

2010 ◽  
Vol 8 (3) ◽  
pp. 459-462 ◽  
Author(s):  
S. M. Mizanur Rahman ◽  
Serajum Munira ◽  
M. Amzad Hossain
Keyword(s):  
Spectral Analysis ◽  
Carboxylic Acid ◽  
Petroleum Ether ◽  
13C Nmr ◽  
Mass Spectral Data ◽  
Phytochemical Study ◽  
Mass Spectral ◽  
New Compounds ◽  
First Time ◽  
Cleome Rutidosperma

Two new compounds were identified as 2-ethyl-cyclohex-2-ene-6-hydroxy-methylene-1-carboxylic acid and 3b-hydroxy-lup-20(29)-en-28-oic acid, respectively, from the petroleum ether extracts of Cleome rutidosperma plant. These two constituents is the first time occurrence in this plant. The structures of the two different type of compounds are elucidated with the help of UV, IR, 1H-NMR, 13C-NMR, COSY, DEPT 90, DEPT 135 and mass spectral data.   Keywords: Cleome rutidosperm DC; isolation; spectral analysis

High Activity of Binuclear Cobalt(II) Complex for Ethylene Evolution from 1-AminocycIopropane-1-carboxylic Acid in the Presence of Hydrogen Peroxide

1999 ◽  
Vol 54 (7-8) ◽  
pp. 534-541 ◽  
Author(s):  
Teruyuki Kobayashi ◽  
Yumiko Sasaki ◽  
Tetsuya Akamatsu ◽  
Toshihiro Ishii ◽  
Yoshiaki Oda ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Carboxylic Acid ◽  
High Activity ◽  
Spectral Data ◽  
Cobalt Complex ◽  
Oxidative Degradation ◽  
Mass Spectral Data ◽  
Ethylene Evolution ◽  
Mass Spectral

Abstract The binuclear Co(II) and Mn(II) complexes with H5(HXTA). where H5(HXTA) repre­sents N,N′-(2-hydroxy-5-methyl-1,3-xylylene)bis(N-carboxymethylglycine), induced a strong ethylene evolution from 1-aminocyclopropane-l-carboxylic acid (ACC) in the presence of hydrogen peroxide, whereas activities of the corresponding Fe(III), Ni(II), and V(III) com­plexes were found negligible. Based on spectroscopic results and mass-spectral data it is proposed that a peroxide adduct of binuclear Co(II) (and Mn(II)) complex with η1-coordina­tion mode interacts with ACC, which is chelated to a binuclear cobalt complex leading to facile oxidative degradation of ACC and to evolution of ethylene.

scholarly journals Green Synthetic Protocol for (E)-1-Aryl-3-(2-morpholinoquinolin- 3-yl)prop-2-en-1-ones and Their Antimicrobial Activity

2019 ◽  
Vol 31 (9) ◽  
pp. 1895-1898
Author(s):  
Relangi Siva Subrahmanyam ◽  
Venkateswara Rao Anna
Keyword(s):  
Antimicrobial Activity ◽  
Spectral Data ◽  
1H Nmr ◽  
13C Nmr ◽  
Mass Spectral Data ◽  
In Vitro Antimicrobial Activity ◽  
Mass Spectral ◽  
Fungal Organisms

We report here an easy, efficient and green synthetic protocol for the (E)-1-aryl-3-(2-morpholinoquinolin-3-yl)prop-2-en-1-ones by the Claisen-Schmidt condensation of 2-morpholinoquinoline-3-carbaldehyde and different substituted acetophenones by using 1-butyl-3-methylimidazolium tetrafluoroborate (Bmim)BF4. The compounds were characterized by using 1H NMR, 13C NMR and mass spectral data and screened there in vitro antimicrobial activity against different bacterial and fungal organisms.

scholarly journals N-(2-(1H-Indol-3-yl)ethyl)-2-(6-methoxynaphthalen-2-yl)propanamide

Molbank ◽  
10.3390/m1187 ◽  
2021 ◽  
Vol 2021 (1) ◽  
pp. M1187
Author(s):  
Stanimir Manolov ◽  
Iliyan Ivanov ◽  
Dimitar Bojilov
Keyword(s):  
Spectral Data ◽  
13C Nmr ◽  
Title Compound ◽  
High Yield ◽  
Mass Spectral Data ◽  
Mass Spectral

The title compound was obtained in high yield in the reaction between tryptamine and naproxen. The newly synthesized naproxen derivative was fully analyzed and characterized via 1H, 13C-NMR, UV, IR, and mass spectral data.

scholarly journals (1R,4S,5S)-5-((3-Hydroxypropyl)amino)-4-((1-Methyl-1H-tetrazol-5-yl)thio)Cyclopent-2-en-1-ol

Molbank ◽  
10.3390/m1199 ◽  
2021 ◽  
Vol 2021 (2) ◽  
pp. M1199
Author(s):  
Milene A. G. Fortunato ◽  
Filipa Siopa ◽  
Carlos A. M. Afonso
Keyword(s):  
Spectral Data ◽  
13C Nmr ◽  
Ring Opening ◽  
Environmentally Friendly ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Excellent Yield ◽  
Ring Opening Reaction ◽  
Nucleophilic Ring Opening

Using environmentally friendly conditions, the nucleophilic ring-opening reaction of 6-azabicyclo[3.1.0]hex-3-en-2-ol with 1-methyl-1H-tetrazole-5-thiol provided a novel thiol-incorporated aminocyclopentitol, (1R,4S,5S)-5-((3-hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol, in excellent yield (95%). The newly synthesized compound was analyzed and characterized via 1H, 13C-NMR, HSQC, and mass spectral data.

The NIH/EPA mass spectral data base and search system

1983 ◽  
Vol 47 ◽  
pp. 313-316 ◽  
Author(s):  
S.R. Heller ◽  
W.L. Budde ◽  
D.P. Martinsen ◽  
G.W.A. Milne
Keyword(s):  
Data Base ◽  
Spectral Data ◽  
Mass Spectral Data ◽  
Search System ◽  
Mass Spectral

Mass spectral data for gas chromatograph-mass spectral identification of some irregular monoterpenes

1976 ◽  
Vol 21 (4) ◽  
pp. 500-502 ◽  
Author(s):  
William W. Epstein ◽  
Lawrence R. McGee ◽  
C. Dale Poulter ◽  
Larry L. Marsh
Keyword(s):  
Spectral Data ◽  
Gas Chromatograph ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Spectral Identification
Sign in / Sign up

Export Citation Format

Share Document