scholarly journals PHYTOCHEMICAL STUDY OF THE ARIAL PARTS OF Cleome rutidosperma DC PLANT

2010 ◽  
Vol 8 (3) ◽  
pp. 459-462 ◽  
Author(s):  
S. M. Mizanur Rahman ◽  
Serajum Munira ◽  
M. Amzad Hossain
Keyword(s):  
Spectral Analysis ◽  
Carboxylic Acid ◽  
Petroleum Ether ◽  
13C Nmr ◽  
Mass Spectral Data ◽  
Phytochemical Study ◽  
Mass Spectral ◽  
New Compounds ◽  
First Time ◽  
Cleome Rutidosperma

Two new compounds were identified as 2-ethyl-cyclohex-2-ene-6-hydroxy-methylene-1-carboxylic acid and 3b-hydroxy-lup-20(29)-en-28-oic acid, respectively, from the petroleum ether extracts of Cleome rutidosperma plant. These two constituents is the first time occurrence in this plant. The structures of the two different type of compounds are elucidated with the help of UV, IR, 1H-NMR, 13C-NMR, COSY, DEPT 90, DEPT 135 and mass spectral data.   Keywords: Cleome rutidosperm DC; isolation; spectral analysis

scholarly journals PHYTOCHEMICAL STUDIES OF THE PETROLEUM ETHER EXTRACT OF THE LEAVES OF Lagerstroemia speciosa Linn

2010 ◽  
Vol 9 (3) ◽  
pp. 500-504
Author(s):  
S.M. Mizanur Rahman ◽  
Shayla Pervin ◽  
Md. Abdul Quader ◽  
M. Amzad Hossain
Keyword(s):  
Petroleum Ether ◽  
1H Nmr ◽  
13C Nmr ◽  
Mass Spectra ◽  
Petroleum Ether Extract ◽  
Ether Extract ◽  
Lagerstroemia Speciosa ◽  
New Compounds ◽  
Phytochemical Studies ◽  
First Time

Two new compounds, normal alcohol containing of higher carbons and isomer of β-sitosterol were isolated for the first time from the petroleum extract of the leaves of Lagerstroemia speciosa. The structure of the compound has been established on the basis of UV, IR, 1H-NMR, 13C-NMR and mass spectra and identified as nonanol and isomer of β-sitosterol.   Keywords: Lagerstroemia speciosa, petroleum ether extracts, isolation, 1-nonanol, 2 β-sitostero, spectral analyses.

scholarly journals Synthesis, Characterization and Screening of Anti-tubercular activity of 2, 5-Disubstituted-1, 3, 4-Oxadiazole

2013 ◽  
Vol 1 (03) ◽  
pp. 12-19
Author(s):  
Alex Martin
Keyword(s):  
Spectral Analysis ◽  
Carboxylic Acid ◽  
Microwave Irradiation ◽  
Hydrazine Hydrate ◽  
Spectral Data ◽  
Acid Hydrazide ◽  
Mass Spectral Data ◽  
Furoic Acid ◽  
Mass Spectral ◽  
Phosphorous Oxychloride

The synthesis of 2-furyl-5-(substituted)-1,3,4-oxadiazoles was carried out by microwave irradiation of 2-furoic acid and ethanol followed by subsequent hydrazinolysis with hydrazine hydrate. Finally furan-2-acid hydrazide was treated with appropriate carboxylic acid in the presence of phosphorous oxychloride to produce title compounds. The structures of the newly synthesized compounds were established on the basis of spectral analysis such as IR, H1NMR and Mass spectral data. The synthesized compounds were screened for their anti-tubercular activity.

scholarly journals Green Synthetic Protocol for (E)-1-Aryl-3-(2-morpholinoquinolin- 3-yl)prop-2-en-1-ones and Their Antimicrobial Activity

2019 ◽  
Vol 31 (9) ◽  
pp. 1895-1898
Author(s):  
Relangi Siva Subrahmanyam ◽  
Venkateswara Rao Anna
Keyword(s):  
Antimicrobial Activity ◽  
Spectral Data ◽  
1H Nmr ◽  
13C Nmr ◽  
Mass Spectral Data ◽  
In Vitro Antimicrobial Activity ◽  
Mass Spectral ◽  
Fungal Organisms

We report here an easy, efficient and green synthetic protocol for the (E)-1-aryl-3-(2-morpholinoquinolin-3-yl)prop-2-en-1-ones by the Claisen-Schmidt condensation of 2-morpholinoquinoline-3-carbaldehyde and different substituted acetophenones by using 1-butyl-3-methylimidazolium tetrafluoroborate (Bmim)BF4. The compounds were characterized by using 1H NMR, 13C NMR and mass spectral data and screened there in vitro antimicrobial activity against different bacterial and fungal organisms.

scholarly journals N-(2-(1H-Indol-3-yl)ethyl)-2-(6-methoxynaphthalen-2-yl)propanamide

Molbank ◽  
10.3390/m1187 ◽  
2021 ◽  
Vol 2021 (1) ◽  
pp. M1187
Author(s):  
Stanimir Manolov ◽  
Iliyan Ivanov ◽  
Dimitar Bojilov
Keyword(s):  
Spectral Data ◽  
13C Nmr ◽  
Title Compound ◽  
High Yield ◽  
Mass Spectral Data ◽  
Mass Spectral

The title compound was obtained in high yield in the reaction between tryptamine and naproxen. The newly synthesized naproxen derivative was fully analyzed and characterized via 1H, 13C-NMR, UV, IR, and mass spectral data.

scholarly journals (1R,4S,5S)-5-((3-Hydroxypropyl)amino)-4-((1-Methyl-1H-tetrazol-5-yl)thio)Cyclopent-2-en-1-ol

Molbank ◽  
10.3390/m1199 ◽  
2021 ◽  
Vol 2021 (2) ◽  
pp. M1199
Author(s):  
Milene A. G. Fortunato ◽  
Filipa Siopa ◽  
Carlos A. M. Afonso
Keyword(s):  
Spectral Data ◽  
13C Nmr ◽  
Ring Opening ◽  
Environmentally Friendly ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Excellent Yield ◽  
Ring Opening Reaction ◽  
Nucleophilic Ring Opening

Using environmentally friendly conditions, the nucleophilic ring-opening reaction of 6-azabicyclo[3.1.0]hex-3-en-2-ol with 1-methyl-1H-tetrazole-5-thiol provided a novel thiol-incorporated aminocyclopentitol, (1R,4S,5S)-5-((3-hydroxypropyl)amino)-4-((1-methyl-1H-tetrazol-5-yl)thio)cyclopent-2-en-1-ol, in excellent yield (95%). The newly synthesized compound was analyzed and characterized via 1H, 13C-NMR, HSQC, and mass spectral data.

scholarly journals Synthesis and Preliminary Evaluation of Benzofuran-Oxadiazole Conjugates as Potential Antitubercular Agents

2019 ◽  
Vol 31 (4) ◽  
pp. 965-970 ◽  
Author(s):  
Veerabhadrayya S. Negalurmath ◽  
Obelannavar Kotresh ◽  
Mahantesha Basanagouda
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Spectral Data ◽  
13C Nmr ◽  
Antitubercular Activity ◽  
Preliminary Evaluation ◽  
Antitubercular Agents ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Mycobacterium Tuberculosis H37rv ◽  
Mycobacterium Phlei

In the present study, a series of benzofuran-oxadiazole conjugates 7(a-o) was designed, synthesized and characterized through IR, 1H NMR, 13C NMR and mass spectral data. All the compounds were screened for preliminary antitubercular activity against Mycobacterium phlei and Mycobacterium tuberculosis H37RV. Among all the target compounds, the compound possessing chlorine (7k, MIC 1.56 μg/mL) and bromine (7m, MIC 1.56 μg/mL) on 6th position of benzofuran showed highest activity against Mycobacterium phlei. Whereas, bromine on either 5th position (7l, MIC 3.125 μg/mL) or 6th position (7m MIC 3.125 μg/mL) on benzofuran exhibited highest activity for Mycobacterium tuberculosis (H37 RV).

Limonoids from Aphanamixis polystachya Leaves and Their Interaction with Hsp90

Planta Medica ◽  
2018 ◽  
Vol 84 (12/13) ◽  
pp. 964-970 ◽  
Author(s):  
César Muñoz Camero ◽  
Antonio Vassallo ◽  
Marinella De Leo ◽  
Abeer Temraz ◽  
Nunziatina De Tommasi ◽  
...  
Keyword(s):  
Molecular Chaperone ◽  
Natural Compounds ◽  
Spectroscopic Methods ◽  
Phytochemical Study ◽  
Phenolic Derivatives ◽  
New Compounds ◽  
Type 3 ◽  
First Time

AbstractA phytochemical study of n-hexane, CHCl3, and CHCl3-MeOH extracts of Aphanamixis polystachya leaves led to the isolation of 10 compounds. Five of them turned out to be new natural compounds, including two mexicanolide-type (1, 2) and three polyoxyphragmalin-type (3–5) limonoids, together with two known andirobin-type limonoids (6, 7) and three phenolic derivatives. The structures of the new compounds were established on the basis of spectroscopic methods to be 8-hydro-14,15-en-cabralin (1), 3-deacetyl-8-hydro-cabralin-14,15-en-3-one (2), 20,22-dihydroxy-21,23-dimethoxytetrahydrofuran khayanolide A (3), 1-deacetyl-3-dehydroxy-3-oxokhaysenelide E (4), and meliaphanamixin A (5). All compounds were isolated for the first time from this species. The ability of the isolated limonoids to interact with the molecular chaperone Hsp90 was tested. Compounds 6 and 7 were the most active.

Mass Spectral Study of D-Sesamin from Phyllarthron comorense

1974 ◽  
Vol 29 (3-4) ◽  
pp. 178-179 ◽  
Author(s):  
Krishna C. Joshi ◽  
R. K. Bansal ◽  
Pahup Singh
Keyword(s):  
Mass Spectrum ◽  
Petroleum Ether ◽  
Spectral Study ◽  
Petroleum Ether Extract ◽  
Mass Spectrometric ◽  
Ether Extract ◽  
Ion Composition ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Mass Spectral Study

Abstract D-Sesamin, Phyllarthron comorense, Mass Spectrum The petroleum ether extract of the heartwood of Phyllarthron comorense DC affords D-sesamin along with paulownin, lapachol, dehydrotectol, dehydro-a-lapachone, /Mapachone, tectol and /5-sitosterol1. We have earlier communicated the mass spectrometric studies of dehydro-a-lapachone2 and paulownin3. The present work deals with the formulation of pos­ sible fragmentation schemes in the case of D-sesamin. This compound is a member of 3,7-dioxabicyclo-Table I. Mass spectral data of D-sesamin a. S. No. m\e Ion composition Relative intensities

Tropane and Pyrrolidine Alkaloids from Convolvulus lanatus Vahl

2008 ◽  
Vol 63 (5-6) ◽  
pp. 321-325 ◽  
Author(s):  
Assem El-Shazly ◽  
Michael Wink
Keyword(s):  
Retention Indices ◽  
Major Constituent ◽  
Mass Spectral Data ◽  
Mass Spectral ◽  
Qualitative And Quantitative ◽  
Alkaloid Composition ◽  
Kováts Retention Indices ◽  
Aerial Parts ◽  
Pyrrolidine Alkaloids ◽  
First Time

The alkaloid composition of Convolvulus lanatus was investigated by GLC and GLCMS. Altogether, thirteen tropane and pyrrolidine alkaloids were identified on the basis of mass spectral data and/or Kovats retention indices. Twelve of them have been recorded for the first time in this plant and some of these alkaloids were identified for the first time in the genus Convolvulus. Cuscohygrine is the major constituent. Qualitative and quantitative differences of root and aerial parts are discussed.

scholarly journals Synthesis and Antimicrobial Activity of 2-(4-Phenyl-2H-chromen-3-yl)-1H-benzo[d]imidazole

2021 ◽  
Vol 33 (8) ◽  
pp. 1723-1728
Author(s):  
Ramachandraiah Dasari ◽  
Gangadhar Thalari ◽  
Jayaprakash Rao Yerrabelly ◽  
Prasad Rao Chitneni
Keyword(s):  
Antimicrobial Activity ◽  
Spectral Data ◽  
Column Chromatography ◽  
13C Nmr ◽  
Mass Spectral Data ◽  
Mass Spectral

A new series of 4-phenyl-2H-chromene-3-benzimidazoles (8a-o) were synthesized by the condensation of 4-phenyl-2H-chromene-3-carbaldehyde with o-phenylene diamines. The products were purified through column chromatography and structures of these compounds were characterized by IR, 1H & 13C NMR and mass spectral data. All the final compounds were screened for their antimicrobial activity and their efficacy were matched with ciprofloxacin. Five compounds (8b, 8d, 8i, 8l and 8o) were found to be most effective compounds of this series and with activities improved than ciprofloxacin under the tested conditions

Sign in / Sign up

Export Citation Format

Share Document