〈1234〉 Vaccines for Human Use—Polysaccharide and Glycoconjugate Vaccines

2021 ◽  
Keyword(s):  
Glycoconjugate Vaccines ◽  
Human Use

STUDY OF POND STATUS IN INDIA : A REVIEW

2017 ◽  
Vol 23 (1) ◽  
Author(s):  
V.K. YADAV ◽  
SONAM SHARMA ◽  
A.K. SRIVASTAVA ◽  
P.K. KHARE
Keyword(s):  
Fresh Water ◽  
Land Surface ◽  
Human Population ◽  
Climate Changes ◽  
Hydrological Cycle ◽  
Habitat Destruction ◽  
Conservation Strategy ◽  
Goods And Services ◽  
Human Use ◽  
Over Exploitation

Ponds are an important fresh water critical ecosystem for plants and animals providing goods and services including food, fodder, fish, irrigation, hydrological cycle, shelter, medicine, culture, aesthetic and recreation. Ponds cover less than 2 percent of worlds land surface. Ponds are important source of fresh water for human use. These are threatened by urbanization, industrialization, over exploitation, fragmentation, habitat destruction, pollution, illegal capturing of land and climate changes. These above factors have been destroying ponds very rapidly putting them in danger of extinction of a great number of local biodiversity. It is necessary to formulate a correct conservation strategy for pond restoration in order to meet the growing needs of fresh water by increasing the human population. Some measures have been compiled and proposed in the present review.

The Hebridean Blackhouse on the Isle of Barra

2000 ◽  
Vol 22 (1) ◽  
pp. 1-16 ◽  
Author(s):  
KEITH BRANIGAN ◽  
COLIN MERRONY
Keyword(s):  
Nineteenth Century ◽  
Internal Space ◽  
Use Of Space ◽  
Large Families ◽  
Human Use

The Hebridean blackhouse is a well-known part of the eighteenth and nineteenth century landscape of the Western Isles, described by numerous early travellers and preserved for posterity at Arnol in Lewis. Survey and excavation of blackhouses on the Isle of Barra, however, suggests that here at least, the majority of blackhouses did not conform to the 'norm' of a long building with accommodation shared by animals and humans. Despite the large families of the Catholic population of Barra, the houses are shorter and provide less internal space than blackhouses further north in the island chain. Animals were more often housed in separate byres. Similarly, the human use of space in the Barra blackhouses shows some variations from the pattern described by nineteenth century sources. As to the origins of the blackhouse, unexcavated sites on Barra suggest two possible future routes of enquiry.

SPECIAL PROBLEMS IN TOXICITY TESTING OF LONG ACTING DEPOT CONTRACEPTIVES

1974 ◽  
Vol 77 (1_Suppla) ◽  
pp. S315-S354 ◽  
Author(s):  
F. Neumann ◽  
R. von Berswordt-Wallrabe ◽  
W. Elger ◽  
K.-J. Gräf ◽  
S. H. Hasan ◽  
...  
Keyword(s):  
Biological Effects ◽  
Histological Finding ◽  
Toxicity Testing ◽  
Prolactin Secretion ◽  
List Type ◽  
Human Species ◽  
Prolactin Plasma Level ◽  
Human Use ◽  
Long Acting ◽  
Reproductive Processes

ABSTRACT Two types of so-called "depot contraceptives", long-acting steroids which are of interest for human use, were studied in animals. Norethisterone oenanthate, mainly gestagenic in the human and other species, turned out to be predominantly oestrogenic in rats. This oestrogenicity caused indirectly, via an enhanced hypophysial prolactin secretion, the well-known hypophysial and mammary tumours in rats. Another synthetic gestagen, 4,6-dichloro- 17- acetoxy- 16α-methyl-4,6-pregnadiene-3,20-dione, which might be considered in its biological actions similar to preparations containing chlormadinone acetate or medroxy-progesterone acetate, induced no signs of oestrogenicity in dogs. It is surmised that its gestagenic influence indirectly, and probaby, via an enhanced hypophysial prolactin secretion caused "mammary nodules" in this "non-rodent" species. These studies have born out mainly two facts: A synthetic steroid, norethisterone oenanthate, exerted different biological effects in different species: it was a gestagen in the rabbit, whereas in rats, its predominant influence was oestrogenic. The hypophysial prolactin secretion was enhanced in various species by different mechanisms: in rats, the oestrogenicity caused an increased prolactin plasma level, whereas in dogs, a gestagen with obviously no inherent oestrogenicity, 4,6-dichloro-17-acetoxy-16α-methyl-4,6-pregnadiene-3,20-dione, converted the histological appearance of the anterior pituitary into a condition with a greatly increased number of eosinophils. This histological finding was interpreted as an indicator for a hypersecretion of prolactin. Hence, animal work with "gestagens" has only limited predictive value with respect to their possible effects in the human species. Therefore, inflexible recommendations are not helpful in solving the safety problem of long-acting steroids which affect primarily reproductive processes.

SATOUMI APPROACH FOR REALIZING SUSTAINABLE COASTAL USE IN A RIASTYPE BAY: A CASE OF SHIZUGAWA BAY IN SANRIKU COAST HIT BY THE HUGE TSUNAMI ON 11 MARCH 2011

2017 ◽  
Author(s):  
Teruhisa Komatsu ◽  
Teruhisa Komatsu ◽  
Shuji Sasa ◽  
Shuji Sasa ◽  
Shigeru Montani ◽  
...  
Keyword(s):  
Local Governments ◽  
Minor Element ◽  
Coupling Model ◽  
Sanriku Coast ◽  
High Productivity ◽  
Biological Coupling ◽  
Miyagi Prefecture ◽  
Human Use ◽  
A Minor ◽  
Aquaculture Facilities

Rias-type bays are one of the most common coasts in Japan where aquacultures have been active due to sheltered geological shape with a deep bottom. The huge tsunami hit Sanriku Coast consisting of open rias-type bays near the epicenter facing Pacific Ocean on 11 March 2011. For recovering Sanriku Coast, it is important to include sustainability in its program. Satoumi is defined as the human use and management of coastal seas for high productivity while maintaining high biodiversity. Therefore, we proposed Satoumi approach to an open rias-type bay, Shizugawa Bay, in southern Sanriku Coast. We conducted scientific researches on mapping of coastal habitats and aquaculture facilities, hydrography, and material flows of nutrients, a minor element (Fe) and organic matters in the bay including those from the rivers and from the offshore waters. At the same time, Committee for Shizugawa Bay Management of Fishermen’s Cooperative of Miyagi Prefecture decided to decrease in aquaculture facilities for sustainable development of aquaculture. Based on these data, a physical-biological coupling model was used for calculating the number of aquaculture facilities that are suitable not only for yields but also for environments. These researches were established on strong collaborations among a fishermen’s’ cooperative, local governments and scientists. Results of this practice may help to realize sustainable coastal use of a rias-type bay.

The Effect of Aircrew Age on +Gz Tolerance as Measured in a Human-Use Centrifuge

1995 ◽  
Author(s):  
Estrella M. Forster ◽  
Barry Shender ◽  
Estrella C. deForster
Keyword(s):  
Human Use

Nanoemulsions- A better Approach for Anti Diabeticdrugs Delivering

2020 ◽  
Vol 17 ◽  
Author(s):  
V. Manimaran ◽  
Ponnurengam Malliappan Sivakumar ◽  
J. Narayanan ◽  
Shanmugam Parthasarathi ◽  
Pranav Kumar Prabhakar
Keyword(s):  
Aqueous Phase ◽  
Therapeutic Agent ◽  
Antidiabetic Drugs ◽  
Optical Behaviour ◽  
Antimicrobial Drugs ◽  
Drug Degradation ◽  
Oil In Water ◽  
Drug Technology ◽  
Human Use ◽  
Poor Absorption

: Conventional delivery of antidiabetic drugs faces many problems like poor absorption, low bioavailability, and drug degradation. Nanoemulsion is a unique drug technology which is very suitable for the delivery of antidiabetic drugs. In recent years the flaws of delivering anti-hypoglycaemic drugs have been overcome by choosing nanoemulsion drug technology. They are thermodynamically stable and also deliver the therapeutic agent for a longer duration. Generally, Nanoemulsions are made up of either oil-in-water or water-in-oil and size of the droplets is from fifty to thousand nanometer. Surfactants are critical substances which are added in the manufacturing of nanoemulsions. Only the surfactants which are approved for human use can be utilized in the manufacturing of nanoemulsions. Generally, the preparation of emulsions includes mixing of the aqueous phase and organic phase and using surfactant with proper agitation. Nanoemulsions are used for antimicrobial drugs, and they are also used in the prophylaxis of cancer, diabetics. Reduction in the droplet size may cause variation in the elastic and optical behaviour of nanoemulsions.

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