Improvement of the method for predicting the risk of ischemic heart disease in workers of the main professions of the coal industry

Author(s):  
N. I. Panev ◽  
S. N. Filimonov ◽  
O. Y. Korotenko

The incidence of ischemic heart disease was detected in 18 (9.2%) coal mine workers (shaft sinkers, stope miners). Based on the determination of the most significant risk markers, a personalized system for ischemic heart disease predicting in miners has been improved allowing for timely carrying out treatment and preventive measures for them.

1989 ◽  
Vol 14 (4) ◽  
pp. 1016-1025 ◽  
Author(s):  
David B. Pryor ◽  
Robert A. Bruce ◽  
Bernard R. Chaitman ◽  
Lloyd Fisher ◽  
Jerzy Gajewski ◽  
...  

1989 ◽  
Vol 14 (4) ◽  
pp. 1025-1034 ◽  
Author(s):  
William L. Haskell ◽  
Norman Brachfeld ◽  
Robert A. Bruce ◽  
Paul O. Davis ◽  
Charles A. Dennis ◽  
...  

2017 ◽  
Vol 0 (7(213)) ◽  
pp. 53-57
Author(s):  
N. M. Shuba ◽  
S. P. Kyriachenko ◽  
Т. D. Voronova ◽  
G. I. Metenkanich ◽  
O. S. Zalutskaya ◽  
...  

2018 ◽  
Vol 15 (2) ◽  
pp. 25-32
Author(s):  
Sangita Shrestha ◽  
Shova Laxmi Bajracharya

Background and Aims: Ischemic Heart Disease (IHD) is the number one cause of morbidity and mortality among the in-patient of different cardiac hospital of developing countries like Nepal. The prevalence of IHD is high with significant associated risk factors that include tobacco use, history of hypertension, family history and age. Though IHD can cause life-threatening conditions like myocardial infarction, yet it is preventable disease. The objective of the study was to study the risk factors associated with ischemic heart diseases among population attending selected cardiac hospitals of Kathmandu.Methods: Hospital- based pair matched case-control was conducted among the patients with IHD at Manmohan Cardiothoracic Vascular and Transplant Centre (MCTVC) and Shahid Gangalal National Heart Center (SGNHC). Non- random purposive sampling technique was applied and sample size was calculated as 105 (35 cases and 70 controls). Case and control were matched with age (Å} 2 years) and sex from the same hospitals. Ethical approval was taken from Institutional review board, Institute of medicine. Informed consent was obtained prior to information collection, after explaining about the purpose of the study to the entire participants. Only interested participants were included in the study. Confidentiality of the subject was ensured by collecting data in separate private room. Univariate associations between the risk factors and IHD under study was assessed by applying Chi-Square test and Fisher’s exact test and expressed as odds ratios with 95% confidence intervals. To assess the strength of association, the odds ratio was calculated.Results: 88.6% cases and 90% controls participants were of age 41 years and above and IHD was more common in male (60%) than female (40%). The participants who were not doing work-related moderate-intense activity are twice more likely to have IHD compared to controls (OR=2.276, p=0.049), similarly, hypertensive are two times (OR=2.276, p=0.049), obese are more than two times (OR=2.44, p=0.045), and participants with high waist to hip ratio are almost three times more likely to suffer from IHD (OR=2.88, p=0.013).Conclusions: The current smoking, physical inactivity, hypertension and waist to hip ratio tend to be the significant risk factors of IHD. Minimizing exposure to the identified risk factors can prevent burden of complex and expensive IHD treatment.


2019 ◽  
Vol 4 (3) ◽  
pp. 52-57 ◽  
Author(s):  
N. I. Panev ◽  
S. N. Filimonov ◽  
O. Yu. Korotenko ◽  
R. N. Panev ◽  
N. Ya. Paneva

Background. Ischemic heart disease is the leading cause of death in the majority of developed countries, including Russia. It determines the importance of elaboration of individual risk prediction of ischemic heart disease for primary prevention.Aim: to develop a strategy for predicting the ischemic heart disease in coal industry workers.Materials and methods. Ischemic heart disease incidence and its risk factors were studied in 196 coalmine workers (sinkers, stope miners). Rose Questionnaire, daily ECG monitoring and bicycle ergometry were used to detect angina. The indices of lipid metabolism, hemostatic system, the level of homocysteine, uric acid, C-reactive protein, constitutional-morphological type by Rees – Eysenck, genetic markers of blood groups of AB0, P and MN systems were studied.When elaborating the prognostic system, we used the Bayes method. A prognostic coefficient was calculated for each factor. Prediction of ischemic heart disease was carried out according to the sum of prognostic coefficients.Results. Ischemic heart disease was detected in 18 (9.2 %) miners. According to the above mentioned indices, a medical technology was elaborated to predict the ischemic heart disease, based on the determination of the most significant risk markers: age, work experience in harmful working conditions, type A behavior, arterial hypertension, fasting hyperglycemia, metabolic syndrome, hypercholesterolemia, decrease in the level of high density lipoprotein cholesterol, increase in the value of low density lipoprotein cholesterol, hypertriglyceridemia, hyperhomocysteinemia, hyperfibrinogenemia, increase in the level of soluble fibrin monomer complexes and C-reactive protein, abdominal obesity, hypersthenic constitutional-morphological type by Rees – Eysenck, genetic markers of blood groups of AB0, P and MN systems.Conclusion. Based on the most significant markers, a personalized strategy for ischemic heart disease prediction in miners was elaborated, which allowed timely undertaking therapeutic and preventive measures.


1997 ◽  
Vol 78 (4) ◽  
pp. 252-254
Author(s):  
E. V. Tsibulina ◽  
A. F. Zharkin ◽  
L. A. Emelyanova

The epidemiologic examination of 962 young women is performed and autopsy reports of 102 women of the same age died of ischemic heart disease are considered. Four leading causes (postgestosis, uterus myoma, menopause, arterial hypertension) are stood out in correlation of the risk factors of ischemic heart disease of living women and those died of this disease. The factors revealed allow to form the risk groups of ischemic heart disease for preventive measures.


2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Paulo Roberto B. Evora ◽  
Julio Nather ◽  
Paulo Victor Tubino ◽  
Agnes Afrodite S. Albuquerque ◽  
Andrea Carla Celotto ◽  
...  

A modern concept considers acute coronary syndrome as an autoinflammatory disorder. From the onset to the healing stage, an endless inflammation has been presented with complex, multiple cross-talk mechanisms at the molecular, cellular, and organ levels. Inflammatory response following acute myocardial infarction has been well documented since the 1940s and 1950s, including increased erythrocyte sedimentation rate, the C-reactive protein analysis, and the determination of serum complement. It is surprising to note, based on a wide literature overview including the following 30 years (decades of 1960, 1970, and 1980), that the inflammatory acute myocardium infarction lost its focus, virtually disappearing from the literature reports. The reversal of this historical process occurs in the 1990s with the explosion of studies involving cytokines. Considering the importance of inflammation in the pathophysiology of ischemic heart disease, the aim of this paper is to present a conceptual overview in order to explore the possibility of curbing this inflammatory process.


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