FEATURES OF THE FUNCTIONAL STATE OF THE CNS AND EFFICIENCY OF MEDICAL WORKERS OF PCR LABORATORIES DURING COVID-19 PANDEMIC

Author(s):  
V.V. Shkarin ◽  
◽  
N.I. Latyshevskaya ◽  
D.V. Orlov ◽  

Abstract: The functional state of the central nervous system was determined by the method of variational chronoreflexometry. The calculated criteria for assessing the functional level of the nervous system (FLS, conventional units), the stability of the nervous reaction (SR, conventional units), the level of functional capabilities of the formed functional system (LFC, conventional units) were analyzed. The observation group was made up of medical workers of PCR laboratories during the COVID-19 pandemic. The results were processed by the variational-statistical method with the calculation of average values (M), representativeness errors (±m), the reliability of differences was determined by the Student's t-test using applied statistical packages Statistica 6.0. It was found that the functional state of the central nervous system in PCR laboratory workers is characterized by the development of significant fatigue and depletion of the functional reserves of the central nervous system, as evidenced by a significant decrease in the level of the formed functional system (FSL) from 2.40±0.04 to 2.13±0.095 units, the stability of the reaction (SR) to 66.25-74.54%. The ability of the central nervous system to form and maintain an adaptive functional system of adaptation to environmental factors significantly decreased by the end of the shift in the observation group by 43.12%- 48.01%. The identified features of the functional state of the central nervous system and the working capacity of medical workers in PCR laboratories during the COVID-19 pandemic will be used for further causation of changes in their health status in difficult working conditions.

Author(s):  
F. L. Azizova ◽  
U. A. Boltaboev

The features of production factors established at the main workplaces of shoe production are considered. The materials on the results of the study of the functional state of the central nervous system of women workers of shoe production in the dynamics of the working day are presented. The level of functional state of the central nervous system was determined by the speed of visual and auditory-motor reactions, installed using the universal device chronoreflexometer. It was revealed that in the body of workers of shoe production there is an early development of inhibitory processes in the central nervous system, which is expressed in an increase in the number of errors when performing tasks on proofreading tables. It was found that the most pronounced shift s in auditory-motor responses were observed in professional groups, where higher levels of noise were registered in the workplace. The correlation analysis showed a close direct relationship between the growth of mistakes made in the market and the decrease in production. An increase in the time spent on the task indicates the occurrence and growth of production fatigue.Funding. The study had no funding.Conflict of interests. The authors declare no conflict of interests.


Author(s):  
A. S. Radilov ◽  
S. A. Solntseva ◽  
I. E. Shkaeva ◽  
S. A. Dulov ◽  
E. V. Vivulanets ◽  
...  

Toxicity and hazard assessment of dioctyl terephthalate (DOTP) was performed in acute, subacute, and chronic experiments, and its principal toxicometry parameters were determined.It was found that on single exposure DOTP exhibits low toxicity and hazard. No resorptive and irritant effects on skin and mucous membrane of eyes were detected in animal experiments. The single inhalation exposure threshold limit value was set at 300 mg/m3, based on the results of monitoring of the functional state of the central nervous system and myocardium and hematological parameters.Thirty-day subacute experiments (oral administration, inhalation exposure, and skin applications) revealed no accumulation of the compound.Four-month chronic exposure to DOTP aerosols (concentration 96,8 mg/m3) caused disorder of the functional state of the central nervous system and myocardium, changes in the hematological and biochemical parameters, gas and acid-base status of the blood, and morphological changes in the lungs and heart. Embryotoxic, genotoxic and gonadotoxic effects were not detected.The chronic inhalation exposure threshold limit value for DOTP (Limch) was set at 18,6 mg/m3, and the concentration of 3,4 mg/m3 was found to be ineffective.The maximum allowable concentration of DOTP in the air of the working area was set at 3,0 mg/m3, hazard class 3.


2020 ◽  
pp. 76-79
Author(s):  
N. P. Setko ◽  
E. V. Bulycheva ◽  
O. M. Zhdanova

Objective: The objective is to determine the features of formation of the functional state of the central nervous system (CNS) and cognitive abilities in children and adolescents of the school age.Methods: The study included 300 school children of general education institution of Orenburg. Functional state of CNS was evaluated with variational chronoreflexometry. Cognitive availabilities have been studied with proof-reading test, Landolt ring.Results: From 7–11 y.o. to 16–17 y.o., there was an increase by 1.5 times in parameters of CNS functional state. Students aged from 7–11 y.o. by 12–15 y.o. demonstrated decrease in processing speed by 1.5 times due to increase of cognitive activity to 1.8 times. From 12–15 y.o. by 16–17 y.o., on the contrary, there was an increase of information processing speed by 1.3 times and decrease of cognitive activity by 2.9 times.Conclusions: The detected features of formation of CNS functional state and cognitive abilities in children and adolescents can be taken into account in when organizing personality-oriented training in educational institutions in order to maintain and increase the level of mental performance and academic performance of students. 


1961 ◽  
Vol 16 (2) ◽  
pp. 361-366 ◽  
Author(s):  
G. W. Granger

Following light adaptation to a luminance of 120 mL for 5 minutes, absolute thresholds for a centrally fixated, 7-degree test field in 'white' light were measured during the course of 30 minutes' dark adaptation. Viewing was monocular and the measuring light was exposed in 0.018-second flashes. The resulting curves, defining the relation between log threshold luminance and time in the dark, displayed the typical features of 'rod' dark adaptation and were found to be highly reproducible in three experienced observers. Neither the shape of the curves nor their position along the log luminance axis was affected by the oral administration of a sedative dose (0.30 gm/70 kg) of amobarbital. It was concluded that the results supported the views of Hecht and other photochemical theorists concerning the stability of human dark adaptation and its resistance to fluctuations in the state of the central nervous system, but were not necessarily incompatible, as was sometimes supposed, with the hypothesis of a neural component in visual adaptation. Submitted on May 23, 1960


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