Rising incidence of celiac disease in the Netherlands; an analysis of temporal trends from 1995 to 2010

2014 ◽  
Vol 49 (8) ◽  
pp. 933-941 ◽  
Author(s):  
Jordy P.W. Burger ◽  
Elisabeth A. Roovers ◽  
Joost P.H. Drenth ◽  
Jos W.R. Meijer ◽  
Peter J. Wahab
Keyword(s):  
Celiac Disease ◽  
The Netherlands ◽  
Temporal Trends ◽  
Rising Incidence

scholarly journals Efficient implementation of the ‘non-biopsy approach’ for the diagnosis of childhood celiac disease in the Netherlands: a national prospective evaluation 2010–2013

2021 ◽  
Author(s):  
Caroline R. Meijer ◽  
Joachim J. Schweizer ◽  
Anne Peeters ◽  
Hein Putter ◽  
M. Luisa Mearin
Keyword(s):  
Celiac Disease ◽  
The Netherlands ◽  
Clinical Presentation ◽  
Paediatric Population ◽  
Hla Typing ◽  
Newly Diagnosed ◽  
Prospective Evaluation ◽  
Espghan Guidelines ◽  
Intestinal Symptoms ◽  
Nationwide Implementation

AbstractThe aim of this study was (1) to prospectively evaluate the nationwide implementation of the ESPGHAN-guidelines for the diagnosis of celiac disease (CD), (2) to investigate the incidence and clinical presentation of diagnosed childhood CD (0–14 years) in the Netherlands, and (3) to compare the findings with national survey data from 1975 to 1990 and 1993 to 2000 using the same approach. From 2010 to 2013, all practicing paediatricians were invited to report new celiac diagnoses to the Dutch Pediatric Surveillance Unit. Data were collected via questionnaires. A total of 1107 children with newly diagnosed CD were reported (mean age, 5.8 years; range, 10 months–14.9 years; 60.5% female). After the introduction of the non-biopsy approach in 2012, 75% of the diagnoses were made according to the guideline with a significant decrease of 46.3% in biopsies. The use of EMA and HLA-typing significantly increased with 25.8% and 62.1%, respectively. The overall incidence rate of childhood CD was 8.8-fold higher than in 1975–1990 and 2.0-fold higher than in 1993–2000. During the study period, the prevalence of diagnosed CD was 0.14%, far below 0.7% of CD identified via screening in the general Dutch paediatric population. Clinical presentation has shifted towards less severe and extra-intestinal symptoms.Conclusion: ESPGHAN guidelines for CD diagnosis in children were effectively and rapidly implemented in the Netherlands. Incidence of diagnosed CD among children is still significantly rising with a continuous changing clinical presentation. Despite the increasing incidence of diagnoses, significant underdiagnosis still remains. What is Known:• Since 2000 the incidence of diagnosed childhood CD in the Netherlands has shown a steady rise.• The rise in incidence has been accompanied by a changing clinical presentation at diagnosis. What is New:• The ESPGHAN guidelines 2012 for CD diagnosis were effectively and rapidly implemented in the Netherlands.• The incidence of diagnosed childhood CD in the Netherlands has continued to rise significantly during the reported period.

scholarly journals Follow-UP Autoantibody Testing and Health Care Utilization Among Patients with (Sustained) Celiac Disease Activity in the Netherlands

2014 ◽  
Vol 17 (7) ◽  
pp. A328
Author(s):  
J.G. Kuiper ◽  
F.J.A. Penning-van Beest ◽  
D. Naessens ◽  
F. Leon ◽  
R.M.C. Herings
Keyword(s):  
Health Care ◽  
Celiac Disease ◽  
The Netherlands ◽  
Health Care Utilization ◽  
Disease Activity ◽  
Care Utilization

scholarly journals Rising incidence, no change in survival and decreasing mortality from thyroid cancer in The Netherlands since 1989

2013 ◽  
Vol 20 (2) ◽  
pp. 263-271 ◽  
Author(s):  
Olga Husson ◽  
Harm R Haak ◽  
Liza N van Steenbergen ◽  
Willy-Anne Nieuwlaat ◽  
Boukje A C van Dijk ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
The Netherlands ◽  
Survival Rates ◽  
Age Groups ◽  
Relative Survival ◽  
Incidence Rates ◽  
Mortality Data ◽  
Netherlands Cancer Registry ◽  
Rising Incidence ◽  
Tumour Node

The incidence of thyroid cancer (TC) is increasing worldwide, partly due to increased detection. We therefore assessed combined trends in incidence, survival and mortality of the various types of TC in The Netherlands between 1989 and 2009. We included all patients ≥15 years with TC, diagnosed in the period 1989–2009 and recorded in The Netherlands Cancer Registry (n=8021). Information on age, gender, date of diagnosis, histological type of tumour and tumour–node–metastasis classification was recorded. Mortality data (up to 1st January 2010) were derived from Statistics Netherlands. Annual percentages of change in incidence, mortality and relative survival were calculated. Since 1989 the incidence of TC increased significantly in The Netherlands (estimated annual percentage change (EAPC)=+1.7%). The incidence rates increased for all age groups (except for females >60 years), papillary tumours (EAPC=+3.5%), T1 and T3 TC (EAPC=+7.9 and +5.8% respectively). Incidence rates decreased for T4 TC (−2.3%) and remained stable for follicular, medullary anaplastic and T2 TC. Five-year relative survival rates remained stable for papillary (88%) and follicular (77%) TC, all age groups and T1–T3 TC (96, 94 and 80% respectively) and somewhat lower for T4 (53%), medullary (65%) and anaplastic TC (5%) in the 2004–2009 period compared with earlier periods. Mortality due to TC decreased (EAPC=−1.9%). TC detection and incidence has been rising in The Netherlands, while mortality rates are decreasing and survival rates remained stable or slightly decreasing.

scholarly journals Temporal trends in incidence of childhood cancer in Switzerland, 1985-2014

2019 ◽  
Author(s):  
Grit Sommer ◽  
Matthias Schindler ◽  
Shelagh Redmond ◽  
Verena Pfeiffer ◽  
Garyfallos Konstantinoudis ◽  
...  
Keyword(s):  
Childhood Cancer ◽  
Temporal Trends ◽  
List Type ◽  
Standard Population ◽  
European Standard Population ◽  
Increasing Trend ◽  
Cns Tumours ◽  
Rising Incidence ◽  
Changes In Risk ◽  
Diagnostic Changes

STRUCTURED ABSTRACTBackgroundIncidence of childhood cancer increased in most countries worldwide, but the reasons are unclear. This study investigates trends in childhood cancer incidence in Switzerland from 1985 to 2014.MethodsWe extracted data on all childhood cancer cases diagnosed at ages 0-14 years in Switzerland from the Swiss Childhood Cancer Registry. We included ICCC-3 main groups I-XII and calculated age-standardised, cumulative, and age-specific incidence for different diagnostic groups. We analysed trends in annual age-standardised incidence using JoinPoint regression models.ResultsOver the study period from 1985-2014, 5104 of 5486 cancer diagnoses (93%) were microscopically verified. The proportion of children treated in paediatric cancer centres increased from 84% during 1985-1994 to 93% in 1995-2004 and 98% in 2005-2014 (p<0.001). Using the 2010 European standard population, age-standardised incidence was 143 in 1985-1994, 154 in 1995-2004, and 162 per million in 2005-2014. Over the period 1985-2014, incidence for all cancers increased by 0.7% (95% confidence interval [CI] 0.5-1.0) per year, 0.8% (95% CI 0.2%-1.4%) for leukaemias, 3.8% (95% CI 1.7%-6.0%) for epithelial neoplasms and melanomas, and 3.0% (95% CI 1.3%-4.6%) for CNS tumours for the period 1985-2002.ConclusionTrends in incidence were driven mostly by increases among leukaemias and CNS tumours. For CNS tumours, observed trends may be explained at least partially by diagnostic changes and improved registration. For leukaemias, rising incidence may be real and at least partly due to changes in risk factors.HighlightsIn Switzerland, incidence of childhood cancer increased by 18% from 1985-2014.Increase in incidence was mainly caused by brain tumours and leukaemias.Improved registration and diagnostics may have increased brain tumour incidence.Increasing trend for leukaemias may be real, but reasons remain elusive.

scholarly journals National laboratory-based surveillance system for antimicrobial resistance: a successful tool to support the control of antimicrobial resistance in the Netherlands

2017 ◽  
Vol 22 (46) ◽  
Author(s):  
Wieke Altorf-van der Kuil ◽  
Annelot F Schoffelen ◽  
Sabine C de Greeff ◽  
Steven FT Thijsen ◽  
H Jeroen Alblas ◽  
...  
Keyword(s):  
Antimicrobial Resistance ◽  
The Netherlands ◽  
Surveillance System ◽  
Data Transfer ◽  
National Laboratory ◽  
Temporal Trends ◽  
Routine Data ◽  
Healthcare Services ◽  
Background Information ◽  
Surveillance Network

An important cornerstone in the control of antimicrobial resistance (AMR) is a well-designed quantitative system for the surveillance of spread and temporal trends in AMR. Since 2008, the Dutch national AMR surveillance system, based on routine data from medical microbiological laboratories (MMLs), has developed into a successful tool to support the control of AMR in the Netherlands. It provides background information for policy making in public health and healthcare services, supports development of empirical antibiotic therapy guidelines and facilitates in-depth research. In addition, participation of the MMLs in the national AMR surveillance network has contributed to sharing of knowledge and quality improvement. A future improvement will be the implementation of a new semantic standard together with standardised data transfer, which will reduce errors in data handling and enable a more real-time surveillance. Furthermore, the scientific impact and the possibility of detecting outbreaks may be amplified by merging the AMR surveillance database with databases from selected pathogen-based surveillance programmes containing patient data and genotypic typing data.

1198 Temporal Trends of Acute Myocardial Infarction-Related Hospitalizations in Celiac Disease Patients

2019 ◽  
Vol 114 (1) ◽  
pp. S674-S674
Author(s):  
Kamesh Gupta ◽  
Ahmad Khan ◽  
Manish Gupta ◽  
Davis Barry ◽  
Abdullah Sohail ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Celiac Disease ◽  
Temporal Trends

Nutritional Management of the Gluten-free Diet in Young People with Celiac Disease in The Netherlands

2006 ◽  
Vol 43 (1) ◽  
pp. 102-108 ◽  
Author(s):  
Erica G.D. Hopman ◽  
Saskia le Cessie ◽  
B. Mary E. von Blomberg ◽  
M. Luisa Mearin
Keyword(s):  
Celiac Disease ◽  
Young People ◽  
The Netherlands ◽  
Gluten Free Diet ◽  
Nutritional Management ◽  
Gluten Free

scholarly journals The many faces of the problem of intolerance to gluten.

2018 ◽  
Vol 96 (2) ◽  
pp. 123-128
Author(s):  
M. A. Livsan ◽  
M. F. Osipenko ◽  
Natalya V. Zayakina ◽  
T. S. Krolevets
Keyword(s):  
Celiac Disease ◽  
Dermatitis Herpetiformis ◽  
Current Data ◽  
Gluten Sensitivity ◽  
Wheat Allergy ◽  
Serological Markers ◽  
Gluten Intolerance ◽  
Rising Incidence ◽  
The Many

Rising incidence of different variants of gluten intolerance associated with changes in eating behaviorin many countries, changes in the technology of growing and processing crops, new culinary technologies. Until recently, celiac disease, dermatitis herpetiformis and wheat allergy were the only known disease with a proven role of gluten in their pathogenesis. Non-celiac gluten sensitivity (NCGS) - a new syndrome of intolerance to gluten. This pathology can be suspected in patients with persistent intestinal and extra-intestinal symptoms clearly associated with the intake of foods containing gluten, the absence of serological markers of celiac disease or suspected allergy to wheat. The paper presents the current data on the epidemiology, etiology and pathogenesis, clinical features and diagnosis NCGS.

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