Comparative Analysis of Anterior Chamber Flare Grading between Clinicians with Different Levels of Experience and Semi-automated Laser Flare Photometry

2014 ◽  
pp. 1-10 ◽  
Author(s):  
Rupesh Agrawal ◽  
Pearse A. Keane ◽  
Jasmin Singh ◽  
Zubin Saihan ◽  
Andreas Kontos ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Anterior Chamber ◽  
Laser Flare Photometry ◽  
Laser Flare ◽  
Different Levels ◽  
Anterior Chamber Flare

Anterior Chamber Laser Flare Photometry After Diode Laser Cyclophotocoagulation

2021 ◽  
pp. 102580
Author(s):  
Ihsan Cakir ◽  
Cigdem Altan ◽  
Gulay Yalcinkaya ◽  
Nese Alagoz ◽  
Banu Solmaz ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Diode Laser ◽  
Laser Flare Photometry ◽  
Laser Flare ◽  
Diode Laser Cyclophotocoagulation

Effect of light backscattering from anterior segment structures on automated flare meter measurements

2021 ◽  
pp. 112067212110393
Author(s):  
Murat Hasanreisoglu ◽  
Cem Kesim ◽  
Duygu Yalinbas ◽  
Mervenur Yilmaz ◽  
Nur Sena Uzunay ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Scattered Light ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Laser Flare Photometry ◽  
Aqueous Flare ◽  
Group I ◽  
Lens Density ◽  
Laser Flare ◽  
Group Ii

Background: To evaluate effect of maximal anterior cortical lens density, iris scatter and anterior chamber depth on laser flare photometry. Methods: Patients diagnosed with clinical uveitis were enrolled in the study. Clinical flare gradings were recorded upon the Standardization of Uveitis Nomenclature. Aqueous flare was measured with an automated device (Kowa FM-700). Back-scattering from anterior cortical lens and anterior iris surface was calculated from Scheimpflug images. A curvilinear regression model was used to calculate estimated values for each clinical grade. These values were used to split cases in Group I (laser flare photometry lower than estimated) and Group II (laser flare photometry higher than estimated). Mean anterior chamber depth, pupil aperture, maximal anterior cortical lens density and iris scatter values were compared between two groups. A stepwise multiple regression analysis was performed to determine the effect of clinical flare gradings and ocular parameters on aqueous flare measurements. Results: The study included 228 eyes of 114 cases. Scheimpflug images were obtained from 105 eyes. Estimated aqueous flare measurements (in photons/milliseconds) were 4.87, 8.50, 14.81, 25.83, 45.04 and 136.93 for 0, 0.5+, 1+, 1.5+, 2+ and 3+ clinical flare respectively. Group II had higher maximal anterior cortical lens density than Group I (96.6 ± 37.1 vs 77.9 ± 17.1 pixel unit, p = 0.001). The measured aqueous flare was significantly related to clinical flare, maximal anterior cortical lens density and pupil aperture (adjusted R2: 0.480, p < 0.001). Conclusion: The back-scattered light from anterior cortical lens could affect laser flare photometry measurements. This effect might be quantified by Scheimpflug imaging.

Correlation between corneal involvement and anterior chamber flare in epidemic keratoconjunctivitis

2019 ◽  
Vol 30 (5) ◽  
pp. 897-900 ◽  
Author(s):  
Pelin Kiyat ◽  
Melis Palamar ◽  
Suzan Guven Yilmaz ◽  
Sinan Emre
Keyword(s):  
Anterior Chamber ◽  
Epidemic Keratoconjunctivitis ◽  
Conjunctival Hyperemia ◽  
Eyelid Edema ◽  
Laser Flare ◽  
The Mean ◽  
The Relationship ◽  
Subepithelial Deposit ◽  
Anterior Chamber Flare ◽  
Laser Flare Meter

Purpose: To investigate the correlation between corneal involvement and anterior chamber flare using a laser flare meter in eyes with epidemic keratoconjunctivitis. Methods: A total of 82 eyes of 50 (32 female and 18 male) consecutive patients with epidemic keratoconjuctivitis were evaluated. Besides complete opthalmic examination, anterior chamber flare measurements with laser flare meter (FM 600, Kowa, Kowa Company Ltd., Nagoya, Japan) were performed. The relationship between corneal involvement, subepithelial deposits, and anterior chamber flare was assessed. Results: The mean age of the patients was 36.32 ± 18.77 (range 4–75) years and the mean duration of complaints was 5.28 ± 2.65 (range 1–12) days. The biomicroscopic findings were conjunctival hyperemia in 82 (100%), follicular reaction in 66 (80.5%), eyelid edema in 56 (68.3%), punctate epitheliopathy in 38 (46.3%), and subepithelial deposits in 36 (43.9%) eyes. The mean flare value was 17.35 ± 12.62 (range 2.0–45.0) photons/ms. Flare measurements were significantly higher in eyes with subepithelial deposits (p < 0.001). Conclusions: Subepithelial deposits seem to occur in eyes with higher anterior chamber inflammation in epidemic keratoconjunctivitis. The laser flare meter might be a useful tool to predict subepithelial deposit development in these patients.

scholarly journals Restraining Inflammation in Pseudoexfoliation Syndrome

2017 ◽  
Vol 10 (01) ◽  
pp. 19
Author(s):  
Marco Coassin ◽  
Luigi Fontana ◽  
◽  
Keyword(s):  
Optical Coherence Tomography ◽  
Cataract Surgery ◽  
Anterior Chamber ◽  
Ophthalmic Solution ◽  
Macular Thickness ◽  
Pseudoexfoliation Syndrome ◽  
Optical Coherence ◽  
Laser Flare Photometry ◽  
Postoperative Inflammation ◽  
Laser Flare

Patients with pseudoexfoliation syndrome (PEX) experience more intense inflammation after phacoemulsification compared to routine cataracts. The effect of topical nonsteroidal anti-inflammatories (NSAIDs) in eyes with PEX have not been studied to date. Laser flare photometry was used in this study to evaluate subtle amounts of postoperative inflammation. The addition of bromfenac to dexamethasone ophthalmic solution significantly reduced anterior chamber inflammation after cataract surgery in PEX when compared to dexamethasone alone. Postoperative macular thickness at optical coherence tomography (OCT) was also positively affected by the addition of topical bromfenac.

scholarly journals Correlation between anterior chamber characteristics and laser flare photometry immediately after femtosecond laser treatment before phacoemulsification

Eye ◽  
2016 ◽  
Vol 30 (8) ◽  
pp. 1110-1117 ◽  
Author(s):  
M Pahlitzsch ◽  
N Torun ◽  
M L Pahlitzsch ◽  
M K J Klamann ◽  
J Gonnermann ◽  
...  
Keyword(s):  
Femtosecond Laser ◽  
Anterior Chamber ◽  
Laser Treatment ◽  
Laser Flare Photometry ◽  
Laser Flare

A comparative study between clinical grading of anterior chamber flare and flare reading using the Kowa laser flare meter

2012 ◽  
Vol 35 (5) ◽  
pp. 629-633 ◽  
Author(s):  
Kallirroi Konstantopoulou ◽  
Roberto Del’Omo ◽  
Anne M. Morley ◽  
Dimitris Karagiannis ◽  
Catey Bunce ◽  
...  
Keyword(s):  
Comparative Study ◽  
Anterior Chamber ◽  
Laser Flare ◽  
Clinical Grading ◽  
Anterior Chamber Flare ◽  
Laser Flare Meter

Oral phospholipidic curcumin in juvenile idiopathic arthritis-associated uveitis

2019 ◽  
Vol 30 (6) ◽  
pp. 1390-1396
Author(s):  
Elisabetta Miserocchi ◽  
Chiara Giuffrè ◽  
Maria Vittoria Cicinelli ◽  
Alessandro Marchese ◽  
Maurizio Gattinara ◽  
...  
Keyword(s):  
Juvenile Idiopathic Arthritis ◽  
Anterior Chamber ◽  
Inflammatory Activity ◽  
Low Grade ◽  
Complete Disappearance ◽  
Slit Lamp ◽  
Slit Lamp Examination ◽  
Laser Flare ◽  
Anterior Chamber Flare ◽  
Laser Flare Meter

Purpose: To evaluate the efficacy and the safety of curcumin-phosphatidylcholine complex in children affected by juvenile idiopathic arthritis–associated uveitis as an adjunctive treatment to chronic systemic immunosuppressive therapy. Methods: In this retrospective, longitudinal study, we treated patients affected by juvenile idiopathic arthritis–associated uveitis with residual low-grade inflammatory activity in the anterior chamber with one tablet of curcumin-phosphatidylcholine complex per day, over a year. Low-grade inflammatory activity was characterized by flare 1+ at slit-lamp examination and 10–50 photon counts per ms) at the FC500 laser flare meter. Inactivity of uveitis was defined as complete disappearance of flare at the slit-lamp examination and values <10 ph/ms at laser flare meter. Conversely, recurrence of the uveitis was defined as a one-step increase from baseline in anterior chamber cells levels or laser flare meter measurements >50 ph/ms. Results: A total of 22 out of 27 patients (81%) achieved inactivity at the end of the study. Five patients (19%) did not show a significant reduction in anterior chamber flare, remaining stable throughout the follow-up. Only three episodes of flare-ups in three different patients were recorded. Overall, the treatment was well tolerated by all patients and no ocular discomfort, ocular side effects, or allergic reactions were registered. Conclusion: Adjunctive therapy with curcumin in patients affected by juvenile idiopathic arthritis–associated uveitis improves mild chronic anterior chamber flare and presents a good safety profile. Despite being mild, anterior chamber inflammation should be minimized to avoid the development of sight-threatening complications in these patients.

scholarly journals Anterior Chamber Flare as an Objective and Quantitative Noninvasive Method for Oculopathy in Transthyretin V30M Amyloidosis Patients

2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
João Beirão ◽  
Vasco Miranda ◽  
Beatriz Pinheiro-Torres ◽  
João Coelho ◽  
Maria-João Menéres ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Comparative Analysis ◽  
Comparative Study ◽  
Anterior Chamber ◽  
Aqueous Humor ◽  
Control Group ◽  
Noninvasive Method ◽  
Cross Sectional ◽  
Fellow Eye ◽  
Anterior Chamber Flare

Purpose. Assess the aqueous humor flare in transthyretin V30M amyloidosis patients (ATTRV30M). Materials and Methods. This is a retrospective, cross-sectional, noninterventional comparative study including 28 ATTRV30M patients with a unilateral scalloped iris. For comparative analysis, the fellow eye, the nonscalloped iris eye, from each patient was used as control. All patients underwent aqueous humor flare meter and intraocular pressure (IOP) measurements. Results. Mean aqueous humor flare was significantly higher in the eyes with the scalloped iris than the control group with the nonscalloped iris (14.1 ± 2.2 versus 6.5 ± 0.9 pc/ms, respectively). No significant differences in IOP were found in the scalloped iris eyes than those in the nonscalloped iris control group (17.1 ± 0.8 versus 16.8 ± 0.7 mmHg, respectively). No significant correlation was not found between the flare and the IOP value within groups. Conclusions. In this study, aqueous humor flare values in the scalloped iris eyes may be a valid marker for controlling the stage of the oculopathy in ATTRV30M patients.

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