The relationship between mean platelet volume with microalbuminuria and glycemic control in patients with type II diabetes mellitus

Platelets ◽  
2011 ◽  
Vol 23 (6) ◽  
pp. 475-480 ◽  
Author(s):  
Mustafa Ünübol ◽  
Medıha Ayhan ◽  
Engın Güney
Keyword(s):  
Diabetes Mellitus ◽  
Glycemic Control ◽  
Mean Platelet Volume ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii ◽  
Platelet Volume ◽  
The Relationship

CORRELATION OF MEAN PLATELET VOLUME WITH GLYCEMIC INDEX IN PATIENTS WITH TYPE II DIABETES MELLITUS – AN OBSERVATIONAL STUDY

2021 ◽  
pp. 24-26
Author(s):  
Anitha .B ◽  
Veena Juliette .A ◽  
Murali. T
Keyword(s):  
Diabetes Mellitus ◽  
Observational Study ◽  
Mean Platelet Volume ◽  
Type Ii Diabetes ◽  
Vascular Complications ◽  
Cost Effective ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii ◽  
Platelet Activity ◽  
Platelet Volume

Type II Diabetes mellitus (TII DM) is a major global health problem. TII DM is characterized by the prothrombotic state of platelets which owes to the persistent hyperglycemia and insulin resistance, causing injury to pericytes and endothelium. Increased platelet activity is believed to be associated with the development of vascular complications in TII DM. Mean Platelet Volume (MPV), a marker of platelet function which can be used to assess the vascular complications. This is an observational study including 150 TII DM patients attending Diabetology OPD in Coimbatore Medical College& Hospital. MPV, FBS, PPBS, HBA1c were signicantly elevated in TII DM patients. Mean FBS, PPBS, HBA1c, MPV were 188.84±91.50mg/dL, 281.10±104.51mg/dL,8.56±2.25 %,9.66 ± 2.02fL, respectively. MPV showed a signicant positive correlation with FBS, PPBS, HBA1c. MPV showed more strong correlation in patients with HBA1c >7% than in patients with HBA1c ≤7%. Our study showed that in Type II Diabetes Mellitus patients, Mean Platelet Volume (MPV) is increased. MPV is signicantly increased in patients with high HBA1c level. Thus, MPV can be taken as a simple and a cost-effective parameter in assessing the Glycemic control in TII DM patients.

scholarly journals Evaluation of the Relationship between Type II Diabetes Mellitus and the Prevalence of Apical Periodontitis in Root-Filled Teeth Using Cone Beam Computed Tomography: An Observational Cross-Sectional Study

2019 ◽  
Vol 28 (6) ◽  
pp. 533-538
Author(s):  
Selen Nihal Sisli
Keyword(s):  
Diabetes Mellitus ◽  
Computed Tomography ◽  
Glycemic Control ◽  
Cone Beam Computed Tomography ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Apical Periodontitis ◽  
Cone Beam ◽  
Control Group ◽  
Type Ii

Objective: This study aimed to investigate the prevalence of apical periodontitis (AP) in patients with type II diabetes mellitus (DM) with either optimal glycemic control (OGC) or poor glycemic control (PGC) compared with nondiabetics using cone beam computed tomography (CBCT). Subjects and Methods: The periapical status of 75 teeth with adequate root canal treatment performed at least 1 year ago that could be visualized in the field of view of CBCT images of 43 DM patients (29 females, 14 males) was compared with a control group consisting of 162 teeth of 86 nondiabetics (56 females, 30 males). In addition, the DM group was divided into subgroups according to the patients’ mean glycated hemoglobin level as either having OGC or PGC. The periapical status of the teeth was evaluated using the CBCT periapical index (CBCTPAI), and AP was diagnosed as a CBCTPAI ≥1. χ2, Fisher’s exact test, and independent-samples t tests were used for the statistical analysis, and p < 0.05 was considered significant. Results: Significant differences between the DM group and the control group were observed (p< 0.05) in terms of AP (the frequencies of both CBCTPAI ≥1 and CBCTPAI ≥3) and the frequency of cardiovascular disease, while there were no significant differences between the DM subgroups (p > 0.05). Conclusion: The prevalence of AP and severe bone destruction in periapical tissues was significantly higher in the DM patients compared with the nondiabetic patients.

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