Endocrine-Disrupting Compounds in Aquatic Ecosystems

2016 ◽  
pp. 338-365
Keyword(s):  
Aquatic Ecosystems ◽  
Endocrine Disrupting Compounds ◽  
Endocrine Disrupting

In vitro assessment of sex steroids and related compounds in water and sediments – a critical review

2018 ◽  
Vol 20 (2) ◽  
pp. 270-287 ◽  
Author(s):  
Chimi Wangmo ◽  
Sergio Jarque ◽  
Klára Hilscherová ◽  
Luděk Bláha ◽  
Michal Bittner
Keyword(s):  
Sex Steroids ◽  
Aquatic Ecosystems ◽  
Endocrine Disrupting Compounds ◽  
Sediment Samples ◽  
Water And Sediment ◽  
Endocrine Disrupting ◽  
In Vitro Assessment ◽  
Related Compounds ◽  
Water And Sediment Samples

Detection of endocrine disrupting compounds in water and sediment samples has gained much importance since the evidence of their effects was reported in aquatic ecosystems in the 1990s.

scholarly journals Synthetic estrogens, their presence in aquatic ecosystems and effects on biota

2020 ◽  
Vol 12 (1) ◽  
pp. 84-101
Author(s):  
Débora Maria Carvalho da Silva ◽  
Cléber Domingos Cunha da Silva
Keyword(s):  
Aquatic Ecosystems ◽  
Emerging Contaminants ◽  
Scientific Literature ◽  
Endocrine Disrupting Compounds ◽  
Water Bodies ◽  
Ecotoxicological Tests ◽  
Online Platforms ◽  
Endocrine Disrupting ◽  
Scientific Papers ◽  
Synthetic Estrogens

Synthetic estrogens are endocrine disrupting compounds that might be in water bodies and, consequently, interfere in hormonal, metabolic and reproductive functions of organisms exposed. This study aims to analyze the international scientific literature about those chemicals through a systematic and narrative review. The investigated estrogens were 17a-ethinylestradiol (EE2), Mestranol (MeEE2), Diethylstilbestrol (DES) and Dienestrol (DNS), which are widely present in pharmaceuticals, consumed and disposed in the environment. For this review, only scientific papers, published from 1990 to 2019, were considered. They were collected in ScienceDirect, PubMed and Scielo online platforms. Introductory information about the compounds, such as their chemical characteristics and use in society were described, as their occurrence in aquatic ecosystems and effects on biota, reported by environmental assessments and ecotoxicological tests, respectively. According to this study, China is the major contributor in quantitative terms, counting 21 articles about synthetic estrogens. Some hormones demonstrated to be more investigated than others; moreover, the increasing of research about those emerging contaminants was noticed. Additionally, Brazilian water bodies revealed to have the highest concentrations, which should encourage critical thinking on its insufficient environmental management. The study also highlights the importance of scientific research expansion and its implementation on truly effective public policies for aquatic ecosystem conservation.

scholarly journals Survey of Intersex (Testicular Oocytes) in Black Crappie Collected from the Illinois River Waterway

2018 ◽  
Vol 9 (2) ◽  
pp. 659-665
Author(s):  
Mark W. Fritts ◽  
Andrea K. Fritts ◽  
Richard M. Pendleton ◽  
Todd D. VanMiddlesworth ◽  
Levi E. Solomon ◽  
...  
Keyword(s):  
Aquatic Ecosystems ◽  
Endocrine Disrupting Compounds ◽  
Morphometric Parameters ◽  
Illinois River ◽  
Future Research ◽  
Pomoxis Nigromaculatus ◽  
Endocrine Disrupting ◽  
Intersex Condition ◽  
Normal Males ◽  
Sport Fish

Abstract Researchers have documented intersex (testicular oocytes) in male fishes in many species worldwide and prevalence of the condition is strongly related to exposure to endocrine-disrupting compounds in aquatic ecosystems. There is no available knowledge about the incidence of intersex in Black Crappie Pomoxis nigromaculatus, an important North American sport fish. The objective of this survey was to investigate the prevalence and distribution of the intersex condition in Black Crappie collected from portions of the Illinois River waterway. We collected and examined 83 Black Crappie. We observed testicular oocytes in 22 individuals (27% intersex), representing the first documentation of intersex condition in wild Black Crappie. The number of oocytes that we observed in intersex Black Crappie ranged from 1 to 67. We documented intersex in individuals collected from all habitats, but there were no significant differences in the prevalence of the condition (Kruskal–Wallis P = 0.56) or the number of oocytes present (P = 0.25) in intersex males from the different habitats. Permutational multivariate analysis of variance indicated that morphometric parameters varied significantly among locations (P = 0.0001), but did not vary significantly between intersex and normal males. We have little information about the current distribution of endocrine-disrupting compounds in the specific regions where we collected Black Crappie for our study. However, we believe our study represents a valuable effort to detect the condition in an important sport fish and lays a foundation for future research.

Nanofiltration of endocrine disrupting compounds

2003 ◽  
Vol 3 (5-6) ◽  
pp. 321-327 ◽  
Author(s):  
M. Gallenkemper ◽  
T. Wintgens ◽  
T. Melin
Keyword(s):  
Wastewater Treatment ◽  
Municipal Wastewater ◽  
Wastewater Treatment Plants ◽  
Endocrine Disrupting Compounds ◽  
Municipal Wastewater Treatment ◽  
Water And Wastewater Treatment ◽  
Wide Range ◽  
Endocrine Disrupting ◽  
Municipal Wastewater Treatment Plants ◽  
Set Up

Endocrine disrupting compounds can affect the hormone system in organisms. A wide range of endocrine disrupters were found in sewage and effluents of municipal wastewater treatment plants. Toxicological evaluations indicate that conventional wastewater treatment plants are not able to remove these substances sufficiently before disposing effluent into the environment. Membrane technology, which is proving to be an effective barrier to these substances, is the subject of this research. Nanofiltration provides high quality permeates in water and wastewater treatment. Eleven different nanofiltration membranes were tested in the laboratory set-up. The observed retention for nonylphenol (NP) and bisphenol A (BPA) ranged between 70% and 100%. The contact angle is an indicator for the hydrophobicity of a membrane, whose influence on the permeability and retention of NP was evident. The retention of BPA was found to be inversely proportional to the membrane permeability.

scholarly journals Effects of the Hedgehog signalling inhibitor itraconazole on developing rat ovaries

2021 ◽  
Author(s):  
Hanna Katarina Lilith Johansson ◽  
Camilla Taxvig ◽  
Gustav Peder Mohr Olsen ◽  
Terje Svingen
Keyword(s):  
Endocrine Disrupting Chemicals ◽  
Endocrine Disrupting Compounds ◽  
Perinatal Period ◽  
Endocrine Function ◽  
Ovary Development ◽  
Knock Out ◽  
Female Reproductive Health ◽  
Endocrine Disrupting ◽  
Hh Signaling ◽  
Knock Out Mice

Abstract Early ovary development is considered to be largely hormone independent, yet there are associations between fetal exposure to endocrine disrupting chemicals and reproductive disorders in women. This can potentially be explained by perturbations to establishment of ovarian endocrine function rather than interference with an already established hormone system. In this study we explore if Hedgehog (HH) signaling, a central pathway for correct ovary development, can be disrupted by exposure to HH-disrupting chemicals, using the antifungal itraconazole as model compound. In the mouse Leydig cell line TM3, used as a proxy for ovarian theca cells, itraconazole exposure had a suppressing effect on genes downstream of HH signaling, such as Gli1. Exposing explanted rat ovaries (gestational day 22 or postnatal day 3) to 30 µM itraconazole for 72 h induced significant suppression of genes in the HH signaling pathway with altered Ihh, Gli1, Ptch1, and Smo expression similar to those previously observed in Ihh/Dhh knock-out mice. Exposing rat dams to 50 mg/kg bw/day in the perinatal period did not induce observable changes in the offspring’s ovaries. Overall, our results suggest that HH signal disruptors may affect ovary development with potential long-term consequences for female reproductive health. However, potent HH inhibitors would likely cause severe teratogenic effects at doses lower than those causing ovarian dysgenesis, so the concern with respect to reproductive disorder is for the presence of HH disruptors at low concentration in combination with other ovary or endocrine disrupting compounds.

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