THE ROLE OF INTERCELLULAR CONTACTS IN THE INDUCTION OF IDO EXPRESSION IN THE ADIPOSE DERIVED MMSCs

Tsitologiya ◽  
2018 ◽  
Vol 60 (5) ◽  
pp. 38-47
Author(s):  
Yu. G. Suzdaltseva ◽  
◽  
K. V. Goryunov ◽  
Yu. P. Rubtsov ◽  
◽  
...  
Keyword(s):  
Intercellular Contacts

The Role of Intercellular Contacts in Induction of Indolamine-2,3-Dioxygenase Synthesis in MMSC from Adipose Tissue

2018 ◽  
Vol 12 (5) ◽  
pp. 391-401
Author(s):  
Yu. G. Suzdaltseva ◽  
K. V. Goryunov ◽  
Yu. P. Rubtsov
Keyword(s):  
Adipose Tissue ◽  
Intercellular Contacts

scholarly journals Bioengineering of Artificial Lymphoid Organs

Acta Naturae ◽  
2016 ◽  
Vol 8 (2) ◽  
pp. 10-23 ◽  
Author(s):  
M. A. Nosenko ◽  
M. S. Drutskaya ◽  
M. M. Moisenovich ◽  
S. A. Nedospasov
Keyword(s):  
Lymphoid Tissue ◽  
Structural Organization ◽  
Polymeric Materials ◽  
Lymphoid Organs ◽  
Cytokine Signaling ◽  
Future Directions ◽  
Intercellular Contacts ◽  
Artificial Tissue ◽  
And Function

This review addresses the issue of bioengineering of artificial lymphoid organs.Progress in this field may help to better understand the nature of the structure-function relations that exist in immune organs. Artifical lymphoid organs may also be advantageous in the therapy or correction of immunodefficiencies, autoimmune diseases, and cancer. The structural organization, development, and function of lymphoid tissue are analyzed with a focus on the role of intercellular contacts and on the cytokine signaling pathways regulating these processes. We describe various polymeric materials, as scaffolds, for artificial tissue engineering. Finally, published studies in which artificial lymphoid organs were generated are reviewed and possible future directions in the field are discussed.

Uptake of3H Prednisolone by Fetal Lung Explants: Role of Intercellular Contacts in Epithelial Maturation

1980 ◽  
Vol 1 (2) ◽  
pp. 111-120 ◽  
Author(s):  
C. K. H. Leung ◽  
I. Y. R. Adamson ◽  
D. H. Bowden
Keyword(s):  
Fetal Lung ◽  
Intercellular Contacts

scholarly journals Morphological manifestations of irritable bowel syndrome

2021 ◽  
Vol 55 (2) ◽  
pp. 108-114
Author(s):  
Yu.M. Stepanov ◽  
I.Ya. Budzak ◽  
Yu.A. Gaidar
Keyword(s):  
Irritable Bowel Syndrome ◽  
Mast Cells ◽  
Tight Junctions ◽  
Intestinal Mucosa ◽  
Morphological Changes ◽  
Low Grade ◽  
Intercellular Contacts ◽  
Irritable Bowel ◽  
Low Grade Inflammation

The article presents modern data on morphological changes in the intestinal mucosa in patients with irritable bowel syndrome. There were analyzed the studies of different years on the morphological manifestations of irritable bowel syndrome. It has been shown that this pathology has an unusual low-grade inflammation. Mast cells play an important role in these inflammatory disorders, they have an effect on motility disorders, visceral hypersensitivity and other pathogenetic factors of irritable bowel syndrome. Disorders of intercellular tight junctions in this category of patients were also analyzed. The role of proteins involved in intercellular contacts (occludin, claudin, ZO) has been characterized. An analysis of the studies investigating these disorders has been carried out. The article provides examples of the analysis of biopsies in patients with irritable bowel syndrome using various methods of their assessment.

The function of fimbriae in Myxococcus xanthus. II. The role of fimbriae in cell–cell interactions

1979 ◽  
Vol 25 (12) ◽  
pp. 1359-1372 ◽  
Author(s):  
W. J. Dobson ◽  
H. D. McCurdy ◽  
T. H. MacRae
Keyword(s):  
Ethylenediaminetetraacetic Acid ◽  
Myxococcus Xanthus ◽  
Gliding Motility ◽  
Cell Aggregates ◽  
Hemagglutination Activity ◽  
Liquid Media ◽  
Electron Microscopic ◽  
Intercellular Contacts ◽  
Per Se

Anti-fimbriae antiserum specifically inhibited swarming but not gliding motility per se in Myxococcus xanthus. However, formation of motile aggregates on agar and clumps in liquid media correlated with the presence of fimbriae. Ethylenediaminetetraacetic acid which inhibited swarming also inhibited fimbriae formation. Direct electron-microscopic observations revealed that fimbriae establish contact with apposing cell surfaces.Intact but not depolymerized fimbriae exhibited hemagglutination activity against guinea pig erythrocytes. This activity was inhibited by mannose, N-acetyl-D-galactosamine, and to a lesser degree by fructose, raffinose. melibiose, and α-methyl-D-mannoside.It is concluded that fimbriae are organelles which function to establish and maintain intercellular contacts, perhaps by a lectin-like function, during the coordinated movement of cell aggregates(swarming) in myxobacteria. This hypothesis is supported by the observations of other workers that genes determining movement of cells in groups also control fimbriation in M. xanthus.

scholarly journals The role of exosomal tetraspanins and proteases in tumor progression

2018 ◽  
Vol 64 (2) ◽  
pp. 123-133 ◽  
Author(s):  
N.V. Yunusova ◽  
E.A. Tugutova ◽  
S.N. Tamkovich ◽  
I.V. Kondakova
Keyword(s):  
Transcription Factors ◽  
Cell Motility ◽  
Tumor Progression ◽  
Tumor Cells ◽  
Significant Contribution ◽  
Migration And Invasion ◽  
Intercellular Contacts ◽  
Igf I

Major (CD9, CD63, CD81) and others (CD82, CD151, Tspan8) tetraspanins are widely represented in exosomes, where they interact with various proteins and form functional tetraspanin complexes. Tetraspanin complexes include proteases. Tetraspanin-associated exosomal proteases (ADAM proteases, MMPs, EMMPRIN) play an important role in the processes of cell motility, migration, invasion and formation of metastases. Also, a significant contribution to tumor progression is made by proteases that are not associated with tetraspanins. They destabilize intercellular contacts, promote migration and invasion of tumor cells, participate in the regulation of the expression IGF-I, VEGF and transcription factors activation/deactivation. The role of other proteases of exosomes in the processes of tumor progression is being clarified.

Role of dactinomycin in the improved survival of children with Wilms' tumor

JAMA ◽  
1966 ◽  
Vol 195 (12) ◽  
pp. 1005-1009 ◽  
Author(s):  
D. J. Fernbach
Keyword(s):  
Wilms Tumor
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