scholarly journals The Effects of a 16-week Aerobic Exercise and Mindfulness-based Intervention on Chronic Psychosocial Stress: A Nonrandomized Pilot and Feasibility Trial

2019 ◽  
Author(s):  
Guy A Prochilo ◽  
Ricardo J.S. Costa ◽  
Craig Hassed ◽  
Richard Chambers ◽  
Pascal Molenberghs
Keyword(s):  
Emotion Regulation ◽  
Exercise Training ◽  
Aerobic Exercise ◽  
Psychosocial Stress ◽  
Retention Rate ◽  
Recruitment Rate ◽  
Aerobic Exercise Training ◽  
Feasibility Trial ◽  
Definitive Trial ◽  
Chronic Psychosocial Stress

Objectives: Researchers have begun delivering mindfulness and aerobic exercise training concurrently on the premise that a combination intervention will yield salutary outcomes over and above each intervention alone. An estimate of the effect of combination training on chronic psychosocial stress in a nonclinical population has not been established. The objective of this trial was therefore to assess the preliminary efficacy of combination training for reducing chronic psychosocial stress in a healthy sample, and to establish assurance of protocol feasibility in preparation of a definitive RCT. Methods: 24 participants were nonrandomized into a single-arm trial and subjected to 16 weeks of concurrent mindfulness psychoeducation and aerobic exercise training. Within-group changes were assessed for chronic psychosocial stress, mindfulness, emotion regulation, and cardiorespiratory fitness. Feasibility criteria were also collected and evaluated. Primary analyses are based on 17 participants. Results: There was a moderate decline in chronic psychosocial stress (d_pretest = -0.56, 95% CI [-1.14, -0.06]). There was an increase in the use of cognitive reappraisal, and a reduction in use of maladaptive emotion regulation strategies. We are insufficiently confident to comment on changes in mindfulness and aerobic capacity (VO2max). However, there were subgroup improvements in aerobic economy at submaximal exercise intensities. Retention rate, response rate, recruitment rate, and sample size analyses indicate a definitive trial is feasible for detecting most effects with precision. Conclusions: This trial provides preliminary evidence of the efficacy of combination training in a nonclinical sample for reducing chronic psychosocial stress. We recommend a definitive trial is feasible and should proceed.

scholarly journals A 16-week aerobic exercise and mindfulness-based intervention on chronic psychosocial stress: a pilot and feasibility study

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Guy A. Prochilo ◽  
Ricardo J.S. Costa ◽  
Craig Hassed ◽  
Richard Chambers ◽  
Pascal Molenberghs
Keyword(s):  
Emotion Regulation ◽  
Exercise Training ◽  
Aerobic Exercise ◽  
Psychosocial Stress ◽  
Retention Rate ◽  
Recruitment Rate ◽  
Trial Registration ◽  
Aerobic Exercise Training ◽  
Definitive Trial ◽  
Chronic Psychosocial Stress

Abstract Objectives Researchers have begun delivering mindfulness and aerobic exercise training concurrently on the premise that a combination intervention will yield salutary outcomes over and above each intervention alone. An estimate of the effect of combination training on chronic psychosocial stress in a nonclinical population has not been established. The objective of this study was to establish protocol feasibility in preparation of a definitive RCT targeting healthy individuals, and to explore the preliminary effect of combination training on reducing chronic psychosocial stress in this population. Methods Twenty-four participants were allocated to a single-arm pre-post study and subjected to 16 weeks of concurrent mindfulness psychoeducation and aerobic exercise training. Feasibility criteria were collected and evaluated. Within-group changes in chronic psychosocial stress, mindfulness, emotion regulation, and cardiorespiratory fitness were also assessed. Primary analyses were based on 17 participants. Results Retention rate, response rate, recruitment rate, and sample size analyses indicate a definitive trial is feasible for detecting most effects with precision. There was also a decline in our primary dependent measure of chronic psychosocial stress (dpretest = −0.56, 95% CI [ −1.14,−0.06]). With regard to secondary measures, there was an increase in the use of cognitive reappraisal, and a reduction in use of maladaptive emotion regulation strategies. We are insufficiently confident to comment on changes in mindfulness and aerobic capacity $\left (\dot {V}O_{2max}\right)$ V ̇ O 2 max . However, there were subgroup improvements in aerobic economy at submaximal exercise intensities. Conclusions We recommend a definitive trial is feasible and should proceed. Trial registration ANZCTR (ID: ACTRN12619001726145). Retrospectively registered December 9, 2019.

Age-Related Attenuation of Aerobic Exercise Training Adaptation in 24-Week Old Rats

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1916-P
Author(s):  
REBECCA L. SCALZO ◽  
GRAHAME F. EVANS ◽  
SARA E. HULL ◽  
LESLIE KNAUB ◽  
LORI A. WALKER ◽  
...  
Keyword(s):  
Exercise Training ◽  
Aerobic Exercise ◽  
Aerobic Exercise Training ◽  
Training Adaptation ◽  
Age Related ◽  
Old Rats

scholarly journals 71 Ultrasound directed reduction of Colles’ type distal radial fractures in ED (UDiReCT): a feasibility randomized controlled trial

2020 ◽  
Vol 37 (12) ◽  
pp. 835.3-836
Author(s):  
Hamza Malik ◽  
Andrew Appelboam ◽  
Gordon Taylor ◽  
Daryl Wood ◽  
Karen Knapp
Keyword(s):  
Data Collection ◽  
Controlled Trial ◽  
Wrist Fracture ◽  
Recruitment Rate ◽  
Feasibility Trial ◽  
Point Of Care Ultrasound ◽  
Distal Radial Fractures ◽  
Definitive Trial ◽  
Randomised Controlled

Aims/Objectives/BackgroundWrist fractures are among the commonest injuries seen in the emergency department (ED). Around 25% of these injuries have Colles’ type fracture displacement and undergo manipulation in the ED. In the UK, these manipulations are typically done ‘blind’ without real time imaging and recent observational studies show that over 40% of the injuries go on to require surgical fixation (due to inadequate initial reduction or re-displacement). Point of care ultrasound has been used to guide and improve wrist fracture reductions but it’s effect on subsequent outcome is not established. We set up and ran the UK’s first randomised controlled feasibility trial comparing standard and ultrasound guided ED wrist fracture manipulations to test a definitive trial protocol, data collection and estimate recruitment rate towards a future definitive trial.Methods/DesignWe conducted a 1:1, single blind, parallel group, randomised controlled feasibility trial in two UK hospitals. Adults with Colles’ type distal radial fractures requiring manipulation in the ED were recruited by supervising emergency physicians supported by network research nurses. Participants were randomised to ultrasound directed fracture manipulation (intervention) or standard care with sham ultrasound (controls). The trial was run through Exeter Clinical Trials Unit and consent, randomisation and data collection conducted electronically in REDCap cloud. All participants were followed up at 6 weeks to record any surgical intervention and also underwent baseline and 3 month quality of life (EQ-5D-5L) and wrist function (Patient Rated Wrist Evaluation (PRWE) assessments.Results/ConclusionsWe recruited 47 patients in total, with 23 randomised to the interventional arm and 24 randomised to the control arm. We were able to follow up 100% of the patients for the 6 week follow up. Data analysis and results will be presented at the time of the conference.

Spleen tissue changes after restraint stress: effects of aerobic exercise training

Stress ◽  
2021 ◽  
pp. 1-12
Author(s):  
Daniele J. Feriani ◽  
Andressa S. Sousa ◽  
Maria Andreia Delbin ◽  
Olívia M. Ruberti ◽  
Carlos C. Crestani ◽  
...  
Keyword(s):  
Exercise Training ◽  
Aerobic Exercise ◽  
Restraint Stress ◽  
Aerobic Exercise Training ◽  
Spleen Tissue ◽  
Stress Effects ◽  
Tissue Changes

scholarly journals Examining Bone, Muscle and Fat in Middle-Aged Long-Term Endurance Runners: A Cross-Sectional Study

2020 ◽  
Vol 9 (2) ◽  
pp. 522
Author(s):  
Ulrike H. Mitchell ◽  
Bruce Bailey ◽  
Patrick J. Owen
Keyword(s):  
Exercise Training ◽  
Aerobic Exercise ◽  
Fat Mass ◽  
Lean Mass ◽  
Aerobic Exercise Training ◽  
Middle Aged ◽  
Cross Sectional ◽  
Endurance Runners ◽  
Total Body

Aerobic exercise training has many known cardiovascular benefits that may promote healthy aging. It is not known if long-term aerobic exercise training is also associated with structural benefits (e.g., lower fat mass, higher areal bone mineral density (BMD) and greater muscle mass). We evaluated these parameters in middle-aged long-term endurance runners compared to sex-, age-, height-, and weight-matched non-running controls. Total and regional lean and fat mass and areal BMD were assessed by dual-energy X-ray absorptiometry. Sagittal magnetic resonance images captured the cross-sectional area and thickness of the lumbar multifidus. Runners (n = 10; all male) had a mean (standard deviation; SD) age of 49 (4) years, height of 178.9 (4.9) cm, weight of 67.8 (5.8) kg, body mass index (BMI) of 21.4 (1.4) kg/m2 and had been running 82.6 (27.9) km/week for 23 (13) years. Controls (n = 9) had a mean (SD) age of 51 (5) years, height of 176.0 (5.1) cm, weight of 72.8 (7.1) kg, and BMI of 23.7 (2.1) kg/m2. BMI was greater in controls (p = 0.010). When compared to controls on average, runners had a 10 percentage-point greater total body lean mass than controls (p = 0.001) and 14% greater trunk lean mass (p = 0.010), as well as less total body (8.6 kg; p < 0.001), arm (58%; p = 0.002), leg (52%; p < 0.001), trunk (73%; p < 0.001), android (91%; p < 0.001), and gynoid fat mass (64%; p < 0.001). No differences were observed between groups for BMD outcomes or multifidus size. These results underscore the benefits of endurance running to body composition that carry over to middle-age.

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