scholarly journals An updated review on Shankhpushpi- As Medhya Rasayana

2021 ◽  
Vol 7 (2) ◽  
pp. 119-123
Author(s):  
Pritika Devi ◽  
Keyword(s):  
Chemical Composition ◽  
Clinical Studies ◽  
Dosage Forms ◽  
Main Ingredient ◽  
Whole Plant ◽  
Review Study ◽  
Memory Enhancer ◽  
Convolvulus Pluricaulis ◽  
The Brain ◽  
Different Parts

Shankhpushpi is a plant and known as best brain tonic medicine which is classified under four Medhya Rasayana by Acharya Charaka. It is also included as main ingredient in many herbal extractives or decoction-based brain tonics or memory boosting formulations. Various Ayurvedacharya have named it as manglayakusuma, ksheerpushpi, medhya etc. Shankhpushi is also comes under convolvulacea family indicated as Convolvulus pluricaulis. The Charaka Samhita, which is an ancient book of Ayurveda described the use of paste (kalka) as Medhya Rasayana. There are so many experimental, pharmacological, clinical studies done on Convolvulus pluricaulis revealed the promising results as neuroprotective, memory enhancer, and antianxiety properties. The studies analysed its chemical composition like convolidine, convolvine, confoline etc. and may help to stimulate the brain activities. In addition, the studies have shown other properties like diuretic, antioxidant, hypolipidemic, hypotensive, antiulcer, antipyretic which helps to manage the various disorders. The various dosage forms like powder, paste, syrup is prepared by using whole plant or different parts of plant as indicated in classical texts. The present review study on Shankhpushpi basically focused on the experimental or clinical studies done in the management of various ailments.

scholarly journals Effects of Different Parts on the Chemical Composition, Silage Fermentation Profile, In Vitro and In Situ Digestibility of Paper Mulberry

Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 413 ◽  
Author(s):  
Yangyi Hao ◽  
Shuai Huang ◽  
Gaokun Liu ◽  
Jun Zhang ◽  
Gang Liu ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Ph Value ◽  
Water Soluble ◽  
Neutral Detergent Fiber ◽  
Soluble Carbohydrate ◽  
Silage Fermentation ◽  
Whole Plant ◽  
Different Parts

Paper mulberry (Broussonetia papyrifera, PM) is high protein but unutilized as a feed source. The study explores the different parts (leaf, stem, and whole plant) of PM chemical composition, silage fermentation, and in vitro and in situ digestibility, aiming to give some guidelines to PM usage as feed. The result showed that the leaf had a higher fresh weight than the stem (p < 0.05). The dry matter contents of the three groups had no differences. The highest crude protein, ether extract, water-soluble carbohydrate, ash, calcium, phosphorus, amino acid contents, and butter capacity were observed in the leaf (p < 0.05). The stem had the highest (p < 0.05) neutral detergent fiber, acid detergent fiber, and lignin contents. After ensiling, the stem silage had the lowest pH value, ammonia nitrate (NH3-N), lactate, acetate, and propionate (p < 0.05). The leaf silage had the highest pH value (p < 0.05). The lactate, acetate, and propionate in the leaf and whole plant silage had no difference. The butyrate was not detected in all silage. The in vitro and in situ digestibility experiments showed the leaf had the highest digestibility (p < 0.05), which could produce more volatile fatty acids and have a higher effective digestibility. These results allow a greater understanding of PM to be used as a feedstuff.

scholarly journals Has molecular imaging delivered to drug development?

2017 ◽  
Vol 375 (2107) ◽  
pp. 20170112 ◽  
Author(s):  
Philip S. Murphy ◽  
Neel Patel ◽  
Timothy J. McCarthy
Keyword(s):  
Molecular Imaging ◽  
Drug Development ◽  
Clinical Studies ◽  
Pharmaceutical Research ◽  
Whole Body ◽  
Drug Candidate ◽  
Clinical Drug Development ◽  
Target Binding ◽  
The Brain ◽  
Clinical Drug

Pharmaceutical research and development requires a systematic interrogation of a candidate molecule through clinical studies. To ensure resources are spent on only the most promising molecules, early clinical studies must understand fundamental attributes of the drug candidate, including exposure at the target site, target binding and pharmacological response in disease. Molecular imaging has the potential to quantitatively characterize these properties in small, efficient clinical studies. Specific benefits of molecular imaging in this setting (compared to blood and tissue sampling) include non-invasiveness and the ability to survey the whole body temporally. These methods have been adopted primarily for neuroscience drug development, catalysed by the inability to access the brain compartment by other means. If we believe molecular imaging is a technology platform able to underpin clinical drug development, why is it not adopted further to enable earlier decisions? This article considers current drug development needs, progress towards integration of molecular imaging into studies, current impediments and proposed models to broaden use and increase impact. This article is part of the themed issue ‘Challenges for chemistry in molecular imaging’.

Somatostatin-Positive Neurons in the Different Parts of the Brain in Normal Aging and Alzheimer's Disease

Neurosignals ◽  
1996 ◽  
Vol 5 (6) ◽  
pp. 343-348 ◽  
Author(s):  
Wei Ping Li ◽  
Helen W.L. Lai ◽  
Suet Ying Cheng ◽  
David T. Yew
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Normal Aging ◽  
The Brain ◽  
Different Parts

Potential Role of Adult Hippocampal Neurogenesis in Traumatic Brain Injury

2021 ◽  
Vol 28 ◽  
Author(s):  
Lucas Alexandre Santos Marzano ◽  
Fabyolla Lúcia Macedo de Castro ◽  
Caroline Amaral Machado ◽  
João Luís Vieira Monteiro de Barros ◽  
Thiago Macedo e Cordeiro ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Clinical Studies ◽  
Molecular Mechanisms ◽  
Hippocampal Neurogenesis ◽  
Cognitive Outcomes ◽  
Adult Hippocampal Neurogenesis ◽  
The Brain

: Traumatic brain injury (TBI) is a serious cause of disability and death among young and adult individuals, displaying complex pathophysiology including cellular and molecular mechanisms that are not fully elucidated. Many experimental and clinical studies investigated the potential relationship between TBI and the process by which neurons are formed in the brain, known as neurogenesis. Currently, there are no available treatments for TBI’s long-term consequences being the search for novel therapeutic targets, a goal of highest scientific and clinical priority. Some studies evaluated the benefits of treatments aimed at improving neurogenesis in TBI. In this scenario, herein, we reviewed current pre-clinical studies that evaluated different approaches to improving neurogenesis after TBI while achieving better cognitive outcomes, which may consist in interesting approaches for future treatments.

Yield, Chemical Composition and Ruminal Fermentability of Corn Whole Plant, Ear, and Stover as Affected by Maturity

jpa ◽  
1989 ◽  
Vol 2 (4) ◽  
pp. 357-361 ◽  
Author(s):  
C. W. Hunt ◽  
W. Kezar ◽  
R. Vinande
Keyword(s):  
Chemical Composition ◽  
Whole Plant

Controlled-release dosage forms and gastrointestinal blood loss: four clinical studies

1993 ◽  
Vol 91 (1) ◽  
pp. 75-84 ◽  
Author(s):  
F. Gilbert McMahon ◽  
Ramon Vargas ◽  
Philip Leese ◽  
Brian Crawford ◽  
Ann Konecny ◽  
...  
Keyword(s):  
Controlled Release ◽  
Blood Loss ◽  
Clinical Studies ◽  
Dosage Forms ◽  
Gastrointestinal Blood Loss

The science and poetry in learning (and teaching) to read

2018 ◽  
Vol 100 (4) ◽  
pp. 13-17
Author(s):  
Maryanne Wolf
Keyword(s):  
Reading Instruction ◽  
Teaching Methods ◽  
Explicit Instruction ◽  
Natural Process ◽  
Teaching Approaches ◽  
Reading Processes ◽  
Learning And Teaching ◽  
Digital World ◽  
The Brain ◽  
Different Parts

Because reading is not a natural process like language, young learners must be taught to read. Knowledge about how the reading brain develops has critical implications for understanding which teaching methods to use and helps reconceptualize previous debates. In this excerpt from Reader Come Home: The Reading Brain in a Digital World, Maryanne Wolf describes how many different parts of the brain must work together when reading and why each requires attention in teaching. She delves into research into different reader profiles, each of which needs different emphases in reading instruction, and she explains the value of teaching approaches that include both explicit instruction in decoding and deep reading processes, and engagement by learner and teacher with the world of words and stories.

scholarly journals Effects of the Harvest Stage of Maize Hybrids on the Chemical Composition of Plant Fractions: An Analysis of the Different Types of Silage

Agriculture ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 786
Author(s):  
Egon Henrique Horst ◽  
Valter Harry Bumbieris Junior ◽  
Mikael Neumann ◽  
Secundino López
Keyword(s):  
Chemical Composition ◽  
Lignin Content ◽  
Neutral Detergent Fiber ◽  
Maturity Stage ◽  
Important Distinction ◽  
Maize Hybrids ◽  
Acid Detergent Lignin ◽  
Whole Plant ◽  
Grain Formation ◽  
Early Harvest

The chemical composition of plant components of three maize hybrids harvested at the beginning of six reproductive stages of maturity was compared. The hybrids evaluated included Maximus VIP3, Defender VIP and Feroz VIP, which were evaluated at each of following stages: R1 (grain formation), R2 (milky grain), R3 (pasty grain), R4 (floury grain), R5 (hard grain) and R6 (ripe grain). The advancement in maturation was linearly related to the crude protein (CP) content of the stem, whole plant, and leaves, and there was a difference among the hybrids. Between R4 and R5 stages, Maximus and Defender presented the highest CP contents for husk (6.58 and 5.42% for Maximus; 5.54 and 5.17% for Defender). The neutral detergent fiber (NDF) of the leaves showed a quadratic relationship with the advancement of maturation but did not differ among the hybrids. For all the hybrids, the NDF content in the husk and cobs increased linearly during the reproductive stages (>77 and 78%, respectively, for the three hybrids in R6). Defender had the lowest NDF content of the cob in R3. The acid detergent lignin contents did not differ among stages in the stems, and showed a linear decrease throughout the whole plant, though the contents did not differ among the hybrids. Due to the differences observed, recommendations for harvest based on the maturity stage for each hybrid should be taken into consideration. There seems to be no important distinction among hybrids for harvesting and use of straw. Despite the reduction in grain yield, an early harvest for earlage or snaplage can provide lower lignin content in husk and cob, as well as higher protein content in the husk, favoring the nutritional value of the vegetative fraction (husk and/or cob).

Sign in / Sign up

Export Citation Format

Share Document