scholarly journals Myocardial load at 30% and 50% of Maximal Voluntary Isometric Contraction in healthy individuals with Active and Sedentary Lifestyle

2020 ◽  
Vol 4 (1) ◽  
pp. 7-11
Author(s):  
Samrudhi Singh ◽  
◽  
Mariya Jiandani ◽  

Background: Activities of daily living consists of isometric & isotonic contraction. Isometric contraction is a static contraction that exerts pressure overload on the heart. Studies have been carried out demonstrating hemodynamic effects of isotonic exercises however limited studies are available on myocardial load with isometric exercises. Aims and Objectives: To study the myocardial load at 30% and 50% of maximal voluntary isometric contraction (MVIC) in individuals with active and sedentary lifestyle. Study design and setting: Observational cross-sectional study was carried out in a tertiary care hospital. Materials and Methods: 140 healthy subjects (70 each in active & sedentary group) were recruited for the study. Baseline demographics of both groups were comparable. Hemodynamic parameters were taken at rest. Subject performed 30% and 50% MVIC and hemodynamic parameters were recorded during and post contraction. Statistical Analysis: Paired t test was used to compare the myocardial load between 30% and 50% MVIC in both groups. Repeated measures ANOVA was used to compare the myocardial load between active & sedentary groups at 30% and 50% MVIC. Result: There was a statistically significant difference in heart rate, systolic blood pressure &rate pressure product between 30% and 50% in active as well as sedentary groups. There was statistically no significant difference in heart rate, systolic blood pressure & rate pressure product between active & sedentary groups at 30% and 50% MVIC. Conclusion: The myocardial load during activities at submaximal intensities (<50%) is within the physiological limits and can be performed safely in individuals with active and sedentary lifestyle.

2012 ◽  
Vol 9 (4) ◽  
pp. 238-243 ◽  
Author(s):  
G S Shrestha ◽  
M N Marhatta ◽  
R Amatya

Background Laryngoscopy and intubation increases blood pressure and heart rate. Objective The study aims to investigate the effect and safety of gabapentin, esmolol or their combination on the haemodynamic response to laryngoscopy and intubation. Methods A total of 72 patients undergoing elective surgery were randomly allocated to one of the four groups. First study drug was administered orally as gabapentin 1200mg or placebo. Second study drug was administered intravenously as esmolol 1.5mg/kg or normal saline. Heart rate, rate pressure product, systolic blood pressure and mean arterial pressure were recorded at baseline and at zero, one, three and five minutes after tracheal intubation. Results Baseline values were compared with the values at various time intervals within the same group. In group PE (placebo, esmolol), there was significant decrease in heart rate and rate pressure product at five minutes. In group GN (gabapentin, normal saline), there was significant decrease in systolic blood pressure and mean arterial pressure at five minutes. In group GE (gabapentin, esmolol), there was significant decrease in heart rate at zero, three and five minutes. Systolic blood pressure, mean arterial pressure and rate pressure product was significantly lower at three and five minutes. In group PN (placebo, normal saline), there was significant increase in heart rate at zero, one, three and five minutes; systolic blood pressure at zero and one minutes; mean arterial pressure at zero and one minutes & rate pressure product at zero, one and three minutes. In group GN (gabapentin, normal saline), there was significant increase in heart rate at zero, one and three minutes & rate pressure product at zero, one and three minutes. In group PE (placebo, esmolol), there was significant increase in systolic blood pressure at zero and one minutes & mean arterial pressure at zero and one minutes. However, in group GE (gabapentin, esmolol) none of the variables showed statistically significant increase at any time. Inter-group comparison was made for each time point. At zero minute, there was significant difference in heart rate between groups PN and GE, GN and PE & GN and GE Significant difference was also noted in rate pressure product between PN and GE at zero minute. At one minute there was difference in heart rate between PN and PE, PN and GE, GN and PE & between GN and GE. Significant difference was observed in rate pressure product between PN and PE & between PN and GE at one minute. No significant side effects of the study drugs were observed. ConclusionsCombination of gabapentin and esmolol in this study design is safe and better attenuates both the pressor and tachycardic response to laryngoscopy and intubation, than either agent alone.DOI: http://dx.doi.org/10.3126/kumj.v9i4.6336 Kathmandu Univ Med J 2011;9(4):238-43 


2020 ◽  
Vol 9 (8) ◽  
pp. e316985536
Author(s):  
Jaqueline Oliveira Barreto ◽  
Julliana Cariry Palhano Freire ◽  
Arthur Willian de Lima Brasil ◽  
Cristian Statkievicz ◽  
Francisley Ávila Souza ◽  
...  

Objective: To assess dental anxiety in patients undergoing oral surgery, as well as its impact on blood pressure and heart rate. Material and Methods: A total of 233 patients answered a socio-demographic questionnaire and another one based on the Corah dental anxiety scale. Blood pressure and heart rate were assessed at three moments while: patients were in the waiting room, immediately before and after the procedure. Results: This study revealed a prevalence of anxiety of 77.3%. There was a statistically significant difference in mean systolic blood pressure and heart rate at the three moments of the evaluation. Anxiety was prevalent in the sample and was observed from the time in the waiting room until the time when local anesthesia was performed, causing variations in systolic blood pressure and heart rate, anxiety levels decreased after the end of the service. In conclusion, we observed that oral surgery is directly related to increased anxiety, and anxiety is mainly related to the change in heart rate.


2020 ◽  
Vol 9 (12) ◽  
pp. 4062
Author(s):  
Ángela Río-González ◽  
Ester Cerezo-Téllez ◽  
Cristina Gala-Guirao ◽  
Laura González-Fernández ◽  
Raquel Díaz-Meco Conde ◽  
...  

The aim of this study is to describe the short-term effects of manual lymph drainage (MLD) isolated in supraclavicular area in healthy subjects. A 4-week cross-sectional, double-blinded randomized clinical trial was conducted. Participants: 24 healthy participants between 18 and 30 years old were recruited from Universidad Europea de Madrid from December 2018 to September 2019. A total of four groups were studied: control, placebo, Vodder, and Godoy. The order of the interventions was randomized. Resting Heart Rate and Oxygen Saturation, blood pressure, pressure pain threshold of trapezius muscle, respiratory rate, range of active cervical movements were measured before and after every intervention. All the participants fulfilled four different interventions with a one-week-wash-out period. No statistically significant differences were found between groups in descriptive data; neither in saturation of oxygen, diastolic blood pressure and cervical range of motion. Significant differences were found in favor of Vodder (p = 0.026) in heart rate diminution and in cardiac-rate-reduction. A significant difference in respiratory rate diminution is found in favor of the Godoy group in comparison with the control group (p = 0.020). A significant difference is found in favor of the Godoy group in systolic blood pressure decrease (p = 0.015) even in pressure pain threshold (p < 0.05). MLD decreases systolic blood pressure in healthy participants. However, it does not produce any changes in other physiologic outcomes maintaining physiologic values, which may suggest the safety of the technique in patients suffering from other pathologies.


2021 ◽  
Vol 12 (3) ◽  
pp. 33-37
Author(s):  
Sankar Roy ◽  
Bidyut Bikas Gharami ◽  
Paramita Pandit ◽  
Arunava Biswas ◽  
Dipasri Bhattacharya ◽  
...  

Background: Hemodynamic change takes place during procedures like laryngoscopy and endotracheal intubation due to reflex sympathetic discharge caused by epipharyngeal and laryngopharyngeal stimulation before a surgery under general anesthesia. Aims and Objectives: The aim of the study was to compare the effectiveness of oral clonidine and intravenous lignocaine as premedicant to obtund the stress response due to such mandatory maneuvers. Materials and Methods: A prospective, randomized, double-blind, double dummy-controlled study was undertaken for 11 months at a tertiary care hospital in the eastern part of India. A total (n=100) patient aged 30 to 50 years of either sex with ASA I and II waiting for elective abdominal surgery were randomized into two equal groups. Group C (n=50) received (4μg/kg) of oral clonidine 90 minute before laryngoscopy and Group L (n=50) received 1.5 mg/kg lignocaine 3 minute before laryngoscopy as active drugs and appropriate placebos were administered as double dummy technique. Comparable demographic and baseline parameters like heart rate, systolic blood pressure and diastolic blood pressure were recorded at various time intervals. Similar anesthesia technique applied was in both the study arm. Result: Attenuation of systolic blood pressure, diastolic blood pressure, heart rate and mean arterial pressure was statistically highly significant (p<0.0001) more in Group C as compared to Group L within first vital 10 minutes of intubation. Conclusion: Oral clonidine attenuates the stress response better than intravenous lignocaine during laryngoscopy and endotracheal intubation with minimum adverse effects.


1990 ◽  
Vol 79 (1) ◽  
pp. 73-79 ◽  
Author(s):  
B. P. M. Imholz ◽  
J. H. A. Dambrink ◽  
J. M. Karemaker ◽  
W. Wieling

1. Continuous orthostatic responses of blood pressure and heart rate were measured in 40 healthy and active elderly subjects over 70 years of age in order to assess the time course and rapidity of orthostatic cardiovascular adaptation in old age. 2. During the first 30 s (initial phase) the effects of active standing and passive head-up tilt closely resembled those observed earlier in younger age groups. Standing up was accompanied by a drop (mean ± SD) in systolic and diastolic blood pressures of 26 ± 13 mmHg and 12 ± 18 mmHg, respectively, at around 10 s, and a subsequent rise up to 11 ± 17 mmHg and 8 ± 6 mmHg above supine values at around 20 s. The drop in blood pressure upon standing was accompanied by a transient increase in heart rate with a maximum of 13 beats/min, followed by a gradual decrease to 7 beats/min above supine levels. These characteristic transient changes were absent upon a passive head-up tilt. 3. After 1–2 min of standing (early steady-state phase) diastolic blood pressure and heart rate increased significantly after active and passive postural changes. On average, for all subjects systolic blood pressure tended to increase from control during 5–10 min standing, reaching a significant difference at 10 min. During standing, the largest increases in systolic blood pressure were found in subjects with the lowest supine blood pressures. 4. In conclusion, for the investigation of orthostatic circulatory responses in elderly subjects the following factors have to be taken into account: active versus passive changes in posture, the timing of the blood pressure reading, and the level of supine blood pressure.


Author(s):  
Abhay Choudhary ◽  
Arun Pathak ◽  
Sheela Kumari

Aims: to know the influence of yoga on autonomic functions of the body. Material and Methods: The present prospective case control study was conducted among patients visited the OPD, Darbhanga Medical College and Hospital, Bihar, India. The findings were tabulated and subjected to statistical analysis. Case group (N=30): subjects who were performing regular yoga asanas and relaxation techniques for at least 5 years. Control group (N=30): age and gender matched subject who were not performing yoga asanas and relaxation techniques or were not engaged with any other type of physical exercises. Results: Amongst the sympathetic nervous system parameters, statistically significant difference existed between cases and controls for the Resting Heart Rate, Resting Diastolic Blood Pressure, Hand grip systolic blood pressure and Hand grip systolic blood pressure (p<0.05) respectively. Conclusion: yogic activity significantly alters the sympathetic activity like heart rate and blood pressure. Keywords: Autonomic Nervous system, Yoga, Heart Rate, Blood Pressure


2018 ◽  
Vol 11 (3) ◽  
Author(s):  
OC Moreira ◽  
CEP Oliveira ◽  
DG Matos ◽  
SF Silva ◽  
RC Hickner ◽  
...  

Objective: To determine and compare the cardiovascular responses to three resistance exercise protocols with different volumes and loads. Methods: The study included 15 healthy subjects, experienced in resistance training, who underwent supine bench press exercise with three different volumes and loads separated by 48 hours, with a crossover model: a) 4 repetitions at 90% of one repetition maximum (4/90%), b) 8 repetitions at 80% of one repetition maximum (8/80%), and c) 15 repetitions at 65% of one repetition maximum (15/65%). Immediately following each protocol, measures of heart rate, systolic and diastolic blood pressure were performed, and were used to calculate the rate pressure product. Results: The 4/90% protocol resulted in an increase in heart rate (Δ = 84.57%; effect size [ES] = 0.31), systolic blood pressure (Δ = 24.03%; ES = 0.42), diastolic blood pressure (Δ = 8.47%; ES = 0.27) and rate pressure product (Δ = 129.65%; ES = 0.54). The 8/80% protocol resulted in changes on: heart rate (Δ = 74.94%; ES = 0.57), systolic blood pressure (Δ = 20.67%; ES = 0.27), diastolic blood pressure (Δ = 6.91%; ES = 0.15) and rate pressure product (Δ = 111.78%; ES = 0.48). The 15/65% protocol resulted in alterations on: heart rate (Δ = 66.77%; ES = 0.39), systolic blood pressure (Δ = 16.85%; ES = 0.35), diastolic blood pressure (Δ = 3.38%; ES = 0.13) and rate pressure product (Δ = 96.41%; ES = 0.30). Increases in all variables pre to post resistance exercise were observed for all protocols (p < 0.05). When comparing the three different protocols, it was found that the heart rate (p < 0.001), systolic blood pressure (p = 0.034) and rate pressure product (p < 0.001), were more elevated in the 4/90% compared to the 15/65%. Conclusion: The bench press exercise performed with low volume and high intensity promotes a more pronounced cardiovascular response compared to the same exercise performed with high volume and low intensity.      


Author(s):  
Priyanka Bhagat ◽  
Mariya Jiandani ◽  
Amita Mehta

Abstract Aims: To assess the cardiovascular response to defecating postures of bridging and sitting lean forward with and without Valsalva maneuver in healthy individuals. Study design: Prospective interventional cross-over study in healthy population. Study material: Stop watch, Rubber tube, Nostril clip, Pillow, Mercury Sphygmomanometer, Cardioscope (Model no.: Iris 50, Maestros company). Materials and methods: A total of 100 healthy individuals participated in the study. They maintained sitting lean forward and in bridging position for 5 minutes with and without Valsalva maneuver. Valsalva maneuver was performed at 40 mm Hg pressure for 15 seconds. Blood pressure and heart rate were recorded. Mean arterial pressure and rate pressure product were derived. Data analysis: The data was analyzed using Statistical Package for the Social Sciences v 16. Shapiro–Wilk test was used to test normality, and nonparametric Mann-Whitney test was used with p < 0.05 as statistically significant. Results: Sitting in lean forward position showed statistical significant increase in heart rate (p < 0.05) compared to bridging position with Valsalva maneuver. There was a significant rise in blood pressure with bridging as compared to sitting lean forward with Valsalva. There was no statistically significant difference in heart rate and blood pressure between sitting lean forward position and bridging position without Valsalva maneuver. Conclusion: Sitting lean forward position and bridging position increase hemodynamic load compared to relaxed sitting posture. With Valsalva maneuver sitting lean forward posture causes greater rise in heart rate compared to bridging position.


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