scholarly journals ACTION OF P-COUMARIC AND CAFFEIC ACIDS AND ULTRAVIOLET-C ON THE ACCUMULATION OF STILBENES AND EXPRESSION OF GENES INVOLVED IN THE BIOSYNTHESIS OF STILBENES IN THE AYAN SPRUCE NEEDLES OF PICEA JEZOENSIS

Author(s):  
A.R. Suprun ◽  
Z.V. Ogneva ◽  
A.S. Dubrovina ◽  
K.V. Kiselev
2019 ◽  
Vol 234-235 ◽  
pp. 133-137 ◽  
Author(s):  
K.V. Kiselev ◽  
V.P. Grigorchuk ◽  
Z.V. Ogneva ◽  
A.R. Suprun ◽  
A.S. Dubrovina

2004 ◽  
Vol 171 (4S) ◽  
pp. 162-162
Author(s):  
Paul Thelen ◽  
Michal Grzmil ◽  
Iris E. Eder ◽  
Barbara Spengler ◽  
Peter Burfeind ◽  
...  

2011 ◽  
Vol 81 (1) ◽  
pp. 34-42 ◽  
Author(s):  
Joel Deneau ◽  
Taufeeq Ahmed ◽  
Roger Blotsky ◽  
Krzysztof Bojanowski

Type II diabetes is a metabolic disease mediated through multiple molecular pathways. Here, we report anti-diabetic effect of a standardized isolate from a fossil material - a mineraloid leonardite - in in vitro tests and in genetically diabetic mice. The mineraloid isolate stimulated mitochondrial metabolism in human fibroblasts and this stimulation correlated with enhanced expression of genes coding for mitochondrial proteins such as ATP synthases and ribosomal protein precursors, as measured by DNA microarrays. In the diabetic animal model, consumption of the Totala isolate resulted in decreased weight gain, blood glucose, and glycated hemoglobin. To our best knowledge, this is the first description ever of a fossil material having anti-diabetic activity in pre-clinical models.


2017 ◽  
Vol 16 (4) ◽  
pp. 141-151 ◽  
Author(s):  
Justyna Leśniowska-Nowak ◽  
Michał Nowak ◽  
Magdalena Zapalska ◽  
Karolina Dudziak ◽  
Krzysztof Kowalczyk

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