Determining LoA between Left Ventricular EF estimated from Abarquez Formula and Left Ventricular EF measured by 2D Echo

2020 ◽  
Vol 11 (5) ◽  
pp. 12-17
Author(s):  
John Carlo B Timbol
Keyword(s):  
Confidence Interval ◽  
Left Ventricular ◽  
Measurement Methods ◽  
Adult Patients ◽  
Limits Of Agreement ◽  
Male And Female ◽  
Female Patients ◽  
Software Comparison ◽  
The Mean ◽  
Mean Differences

Background: The Abarquez formula (aVR QRS amplitude x 2.264) + (age x 0.645) has been offered to provide an estimate for LVEF measured by 2D Echo. However, studies aiming to establish agreement between the Abarquez formula and LVEF measured by 2D Echo are lacking. Aims and Objectives: The aim of this study was to compare the LVEF estimated from 12-lead ECG using the Abarquez formula with the LVEF measured using the 2DED in the following subpopulations: 18-35 years old, 36-60 years old, >60 years old, male, and female patients. To compare these two measurements, the limits of agreement (LoA) by Altman and Bland was used. Materials and Methods: Adult patients admitted in the VLMC from January to May 2019 with both a 12-lead ECG and a 2D Echo were included in the study. LVEF from 2D Echo and LVEF estimated using the Abarquez formula were recorded. Comparison of the two measurements was performed by Altman and Bland method using LoA at 95% confidence interval. This analysis was done using Analyse-It Software. Comparison of the mean differences between the two measurement methods was also done using STATA. Results: LVEF estimate using the Abarquez formula was found to significantly differ from LVEF measured using 2D Echo. Conclusions: The Abarquez formula cannot be used as a surrogate for LVEF measure by 2D Echo.

scholarly journals Strengths among Contemporary Teenagers: A Comparative Study

2017 ◽  
Vol 4 (2) ◽  
Author(s):  
Ritu Rani ◽  
Punam Midha ◽  
Ankita Budhiraja
Keyword(s):  
Harmonious Society ◽  
Descriptive Statistics ◽  
Female Adolescents ◽  
Male And Female ◽  
Signature Strengths ◽  
Fast Speed ◽  
The Mean ◽  
Mean Differences ◽  
Age Range ◽  
Purposive Sample

Male and female are two indispensible wheels of a chariot, thus both complement each other and this is a fact that without any one of them, it is just impossible to imagine the smooth continuation of the journey of life. India is a country where women were worshiped as Goddess. Though the society in which we live has been shaped historically by males. But recently the existing scenario appears to be changing with the realization of strengths among females. A harmonious society appears to be emerging with the fast speed of decline in gender-specificity. In order to empirically confirm these notions, the present researchers decided to explore and compare the profile of strengths of male-female adolescents. A test of Hindi adaptation of Value In Action (VIA) Inventory of Strengths for Youth by Shree and Singh (2013) was used. A purposive sample of 150 adolescents in which 75 were males and 75 were females with the age range of 13-17 years was drawn from Rohtak city, Haryana. The descriptive statistics was used to find out the mean differences in strengths of male and female adolescents. They differed to some extent in their profile of signature strengths. Further the profile of top five strengths also called “signature strengths”, the male and female differed in two out of five signature strengths. The similar signature strengths found in both male and female adolescents were such as judgment/critical thinking, appreciation of beauty and love, however they differed on two strengths such as zest and perspective were found in male while kindness and modesty were found in female. The inference drawn from the current study is that females are more humane than the male counterpart whereas males are found to be more courageous than females. The need to foster or enhance certain strengths in specific gender are discussed in the paper.

scholarly journals On Jones et al.’s Method for Assessing Limits of Agreement with the Mean for Multiple Observers

2020 ◽  
Author(s):  
Heidi S. Christensen ◽  
Jens Borgbjerg ◽  
Lars Børty ◽  
Martin Bøgsted
Keyword(s):  
Confidence Intervals ◽  
Random Effects ◽  
Tumour Size ◽  
Measurement Methods ◽  
Data Sets ◽  
Random Effects Model ◽  
Limits Of Agreement ◽  
Continuous Measurements ◽  
Multiple Measurements ◽  
The Mean

Abstract Background To assess the agreement of continuous measurements between a number of observers, Jones et al. introduced limits of agreement with the mean (LOAM) for multiple observers, representing how much an individual observer can deviate from the mean measurement of all observers. Besides the graphical visualisation of LOAM, suggested by Jones et al., it is desirable to supply LOAM with confidence intervals and to extend the method to the case of multiple measurements per observer.Methods We reformulate LOAM under the assumption the measurements follow an additive two-way random effects model. Assuming this model, we provide estimates and confidence intervals for the proposed LOAM. Further, this approach is easily extended to the case of multiple measurements per observer.Results The proposed method is applied on two data sets to illustrate its use. Specifically, we consider agreement between measurements regarding tumour size and aortic diameter. For the latter study, three measurement methods are considered. Conclusions The proposed LOAM and the associated confidence intervals are useful for assessing agreement between continuous measurements.

scholarly journals Single-Breath-Hold Evaluation of Cardiac Function with Use of Time-Resolved Parallel Cardiac Magnetic Resonance

2017 ◽  
Vol 44 (4) ◽  
pp. 252-259 ◽  
Author(s):  
Patrick Krumm ◽  
Jonas D. Keuler ◽  
Stefanie Mangold ◽  
Tanja Zitzelsberger ◽  
Christer A. Ruff ◽  
...  
Keyword(s):  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Left Ventricular ◽  
Breath Hold ◽  
Functional Evaluation ◽  
Time Resolved ◽  
Single Breath ◽  
Single Breath Hold ◽  
The Mean ◽  
Mean Differences

Using cardiac magnetic resonance, we tested whether a single-breath-hold approach to cardiac functional evaluation was equivalent to the established multiple-breath-hold method. We examined 39 healthy volunteers (mean age, 31.9 ± 11.4 yr; 22 men) by using 1.5 T with multiple breath-holds and our proposed single breath-hold. Left ventricular and right ventricular ejection fractions (LVEF and RVEF), LV and RV end-diastolic volumes (LVEDV and RVEDV), and LV myocardial mass (LVMM) were compared by using Bland-Altman plots; LVEF and RVEF were tested for equivalence by inclusion of 95% confidence intervals (CIs). Equivalence of the methods was assumed within the range of −5% to 5%. In the multiple- versus the single-breath-hold method, LVEF was 0.62 ± 0.05 versus 0.62 ± 0.04, and RVEF was 0.59 ± 0.06 versus 0.59 ± 0.07. The mean difference in both methods was −0.2% (95% CI, −1 to 0.6) for LVEF and 0.3% (95% CI, −0.8 to 1.5) for RVEF. The mean differences between methods fit within the predetermined range of equivalence, including the 95% CI. The mean relative differences between the methods were 3.8% for LVEDV, 4.5% for RVEDV, and 1.6% for LVMM. Results of our single-breath-hold method to evaluate LVEF and RVEF were equivalent to those of the multiple-breath-hold technique. In addition, LVEDV, RVEDV, and LVMM showed low bias between methods.

Olanzapine in adolescent and young adult patients with schizophrenia: findings in male and female patients

2005 ◽  
Vol 38 (05) ◽  
Author(s):  
RW Dittmann ◽  
U Hagenah ◽  
J Junghanß ◽  
A Mästele ◽  
C Mehler-Wex ◽  
...  
Keyword(s):  
Young Adult ◽  
Adult Patients ◽  
Adolescent And Young Adult ◽  
Male And Female ◽  
Female Patients

scholarly journals Autologous Osteochondral Transplantation for Osteochondral Lesions of the Talus: Does Gender Impact Outcomes?

2020 ◽  
Vol 5 (4) ◽  
pp. 2473011420S0022
Author(s):  
Arianna L. Gianakos ◽  
Olasunmbo Okedele ◽  
Sean Flynn ◽  
John G. Kennedy ◽  
Christopher W. DiGiovanni
Keyword(s):  
Osteochondral Lesions ◽  
Symptom Duration ◽  
Osteochondral Transplantation ◽  
Autologous Osteochondral Transplantation ◽  
Duration Of Symptoms ◽  
Male And Female ◽  
Female Patients ◽  
Male Patients ◽  
The Mean

Category: Ankle; Arthroscopy Introduction/Purpose: Autologous osteochondral transplantation (AOT) is commonly used in the treatment of osteochondral lesions (OCL) of the talus. There is limited data comparing gender differences in the incidence, presentation, and outcomes following AOT. The purpose of this study is to compare these differences between male and female patients. Methods: Eighty-five consecutive patients who underwent AOT were retrospectively reviewed. Patients were divided into two groups based on gender. Demographic data and OCL defect characteristic data were recorded. Functional outcomes were assessed pre- and post-operatively using the Foot and Ankle Outcome Score (FAOS). The Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score was used to assess cartilage incorporation. The mean clinical follow-up was 47.2 months, with mean MRI follow-up of 24.8 months. Results: Fifty-five (65%) males and 30 (35%) females were included. OCL defect size was significantly larger in men (112.8mm2) when compared with women (88.7mm2) (p<0.0001). Male patients had a significantly longer duration of symptoms (p<0.001) and OCLs were more likely traumatic in nature (p=0.0006) when compared with female patients. Mean FAOS improved pre- to postoperatively from 50 to 81(P < .001) with a statistically significant increase in men (p<0.0001). The mean MOCART score was 82.1 and 86.7 in male and female patients, respectively (p<0.0001). Lesion size was negatively correlated with MOCART score (r = -0.36,P = .004). No differences were found in knee donor site morbidity, complication rate, or revision surgery. Conclusion: Our study demonstrates that male patients typically present with talar OCLs that are larger in size, traumatic in nature, and with longer symptom duration when compared with female patients. In addition, male patients had greater improvement in FAOS scores following AOT. Therefore, understanding these differences may influence the management and treatment of talar OCLs in male and female patients.

scholarly journals A Comparison of Two Transcutaneous Monitors for the Measurement of Arterial Po2 and Pco2 in Neonates

1995 ◽  
Vol 23 (6) ◽  
pp. 708-714 ◽  
Author(s):  
B. Carter ◽  
M. Hochmann ◽  
A. Osborne ◽  
A. Nisbet ◽  
N. Campbell
Keyword(s):  
Sensitivity And Specificity ◽  
Electrode Temperature ◽  
Average Sensitivity ◽  
Limits Of Agreement ◽  
Hewlett Packard ◽  
Transcutaneous Oxygen ◽  
The Mean ◽  
Mean Differences ◽  
Lower Limits ◽  
Arterial Po2

We examined the ability of two transcutaneous devices (Fastrac, Sensormedics Corporation, Yorba Linda, California, U.S.A. and Hewlett Packard M1018A, Hewlett Packard Component Monitoring System, Hewlett Packard, North Hollywood, U.S.A.) to measure arterial Pco2 and Po2 in neonates. Thirty-seven neonates had transcutaneous oxygen measured with the Hewlett Packard (HPo2 group), 38 neonates had transcutaneous carbon dioxide measured with the Hewlett Packard (HPco2 group) and the Fastrac was used on 27 neonates (FTco2 group). Both devices were operated with electrode temperatures of 43.5 °C although an additional ten subjects were studied using the Fastrac with an electrode temperature of 43.0°C. The mean differences (transcutaneous—arterial) and upper and lower limits of agreement were calculated for each group. For the HPo2 group they were 3.78 mmHg (-12.23 to 19.80 mmHg), for the HPco2 group they were 0.40 mmHg (-4.50 to 5.30 mmHg) and for the FTco2 they were - 0.96 mmHg (- 7.85 to 5.92 mmHg). For the Fastrac group at an electrode temperature of 43.0°C the mean difference and limits of agreement were -1.00 mmHg and -4.58 mmHg to 2.58 mmHg. The average sensitivity and specificity for both machines for the detection of hypocarbia were 82% and 92% respectively while for hypercarbia they were 90% and 94% respectively. For hypoxaemia, the sensitivity and specificity were 40% and 94% while for hyperoxaemia the sensitivity and specificity were 83% and 97%. We conclude that both machines provide a useful supplement to arterial Pco2 measurements and the Fastrac performs better at 43.0°C. The measurement of Po2 is less accurate but is still of clinical use.

scholarly journals Assessing bone thickness in the infrazygomatic crest area aiming the orthodontic miniplates positioning: a tomographic study

2017 ◽  
Vol 22 (4) ◽  
pp. 70-76 ◽  
Author(s):  
Aline Rode Santos ◽  
Marcelo Castellucci ◽  
Iêda Margarida Crusoé-Rebello ◽  
Márcio Costa Sobral
Keyword(s):  
Computerized Tomography ◽  
Adult Male ◽  
Adult Patients ◽  
Cone Beam ◽  
Bone Thickness ◽  
Cross Sectional ◽  
Male And Female ◽  
Measurement Results ◽  
Cone Beam Computerized Tomography ◽  
The Mean

ABSTRACT Introduction: Due to the increasing use of miniplates for anchorage purposes in orthodontics, it is very important to know more about infrazigomatic crest anatomy (thickness), in adult patients. Objectives: Evaluate the infrazygomatic crest region thickness, in adult (male and female) patients. Methods: Cone-beam computerized tomography (CBCT) images from 40 patients were used to assess cross-sectional measurements of the infrazygomatic crest region. Measurement 1 considered thickness 2 mm above the distobuccal root of the permanent maxillary first molar, while measurement 2 was taken 2 mm above the first measurement. Results: The mean thickness of the infrazygomatic crest in males was 3.55 mm for measurement 1 and 2.84 mm for measurement 2, while in females these were 2.37 mm and 2.24 mm, respectively. Conclusion: The authors concluded that the overall mean thickness of the infrazygomatic crest was 2.49 mm with respect to measurement 1, and 2.29 mm for measurement 2, with no statistically significant differences between gender.

scholarly journals Impact of gender in patients with continuous-flow left ventricular assist device therapy in end-stage heart failure

2021 ◽  
pp. 039139882110067
Author(s):  
Alina Zubarevich ◽  
Marcin Szczechowicz ◽  
Anja Osswald ◽  
Arian Arjomandi Rad ◽  
Robert Vardanyan ◽  
...  
Keyword(s):  
Heart Failure ◽  
Continuous Flow ◽  
Female Gender ◽  
Left Ventricular ◽  
Assist Device ◽  
Ventricular Assist ◽  
Male And Female ◽  
Female Patients ◽  
Left Ventricular Assist

Background: There is an ongoing debate about the influence of the female gender on postoperative outcomes after durable left ventricular assist device (LVAD) implantation. Despite the differences in pathophysiology of heart failure in females, therapy concepts are the same as in the male population. The aim of this study was to investigate the role of the female gender in surgical heart failure therapy. Materials and methods: Between August 2010 and January 2020, 207 patients were treated with durable LVAD at out institution. We matched 111 patients in two groups to compare the outcomes in male and female patients and to stratify the risk factors of mortality. Results: The groups were matched 2:1 and were comparable after matching. We found no difference in in-hospital and follow-up mortality between male and female patients. Postoperative adverse events and complications were found to be unvaried across male and female patients. Female patients had higher rates of postoperative LVAD-thrombosis compared to their male counterparts (13.5% vs 0, p = 0.001) and the rates of renal replacement therapy lasting over 90 days were also higher in the female group (33.8% vs 56.8%, p = 0.021). Furthermore, the female gender was not an independent predictor neither of in-hospital nor follow-up mortality. Conclusions: Durable continuous flow left ventricular assist devices as a bridge to transplantation or recovery in female patients are associated with a higher risk of acute kidney injury requiring RRT and are at a higher risk of LVAD-thrombosis. Nevertheless, survival rates between genders are similar.

scholarly journals Gender Influences on Colour processing: An event related potential (ERP) study

2018 ◽  
Vol 17 (4) ◽  
pp. 612-618 ◽  
Author(s):  
Rumaisa Abu Hasan ◽  
Faruque Reza ◽  
Tahamina Begum
Keyword(s):  
Medical Science ◽  
Electrode System ◽  
Event Related Potential ◽  
Female Group ◽  
Occipital Area ◽  
Male And Female ◽  
Male Group ◽  
The Mean ◽  
Mean Differences ◽  
Gender Influences

Background: We assessed cognitive function by using different colours. Colour has been used in different neuropsychology tests for diagnostic and therapeutic purposes.Purposes: As male and female hormones are different, it is important to investigate the effect of different colours on the male and female groups for planning their therapeutic strategy in different diseases.Methods: This prospective study was done between 2012 and 2014. We used the 128-sensor net for an event related potential (ERP) study in male and female groups (n= 22 in each group). Different colours were used as stimuli. Subjects pressed ‘button 1’ when they liked the colour and ‘button 2’ when they disliked it. Reaction time (RT) and differences in like and dislike stimuli were analysed. The values of the mean differences of like and dislike stimuli were calculated using a 10-20 electrode system of 19 electrodes. The amplitudes and latencies of the N200 and P300 ERP components were analysed.Results: No significant differences were found in the mean differences of the amplitudes and latencies of the N200 and P300 ERP components between the male and female groups across 19 electrode sites. RTs were non-significantly longer in the male group. However, colour reflected on the frontal-right occipital area in the female group and the frontal-left occipital area in the male group.Conclusion: There might be a possibility of delayed decision-making due to difficulty assessing emotion in the male group compared with the female group.Bangladesh Journal of Medical Science Vol.17(4) 2018 p.612-618

scholarly journals Simple Linear Calculating Method of Glenoid Bone Defects Using 3-Dimensional Computed Tomography Based on an East Asian Population in China

2020 ◽  
Vol 8 (4) ◽  
pp. 232596712091427
Author(s):  
Xing-zuo Chen ◽  
Tong-xi Liu ◽  
Ying Chen ◽  
Lei Du ◽  
Wei-fang Liu ◽  
...  
Keyword(s):  
Computed Tomography ◽  
East Asian ◽  
Asian Population ◽  
Bone Defects ◽  
East Asian Population ◽  
Ct Scans ◽  
Male And Female ◽  
Female Patients ◽  
The Mean ◽  
The Relationship

Background: The evaluation of glenoid bone defects in the preoperative stage for patients with anterior shoulder instability is critical for surgical decision making. A novel method that predicts the intact glenoid width based purely on the measurement of the glenoid height has been advocated. Despite the convenience, all studies to date have focused on the Western population, and there is no similar research based on an East Asian population. Purpose: To determine the relationship between glenoid height and width in an East Asian population. Study Design: Cross-sectional study; Level of evidence, 3. Methods: Spiral computed tomography (CT) scans of both sides of the shoulder joints were obtained from 205 patients of Han nationality (China) who had no history of shoulder trauma or pain. The maximal height and width of each glenoid were measured on the en face view by 2 radiologists who were blinded to each other’s results. Pearson correlation coefficients and multivariable linear regression were calculated from all data measured to evaluate the relationship between maximal glenoid height and width between the sexes. Results: A total of 205 patients (410 shoulder CT scans) were analyzed. The mean glenoid height was 34.45 ± 2.82 mm, and the mean glenoid width was 23.35 ± 2.40 mm. There was a statistical difference between male and female patients with regard to glenoid height (36.61 vs 32.39 mm, respectively; t = 9.76; P < .001) and width (25.26 vs 21.54 mm, respectively; t = 20.73; P < .001). Analysis of the measured glenoid height and width demonstrated a strong linear correlation of 0.82 ( R 2 = 0.68; P < .001) for the entire cohort and similarly strong linear correlations when each sex was analyzed separately. For male patients, the glenoid width was measured as: glenoid height × 0.50 + 7 mm ( R 2 = 0.36; P < .001); for female patients, the glenoid width was measured as: glenoid height × 0.45 + 7 mm ( R 2 = 0.31; P < .001). Conclusion: In an East Asian population, the mean glenoid height and width were 34.45 and 23.35 mm, respectively. The formulas that represent the relationship between glenoid width and height for male and female patients are the following: glenoid width = glenoid height × 0.50 + 7 mm and glenoid width = glenoid height × 0.45 + 7 mm, respectively.

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