Dorsal expansion-related manual disability in verrucae vulgaris patients treated with cryotherapy: A longitudinal study via big data

2021 ◽  
Vol 12 (4) ◽  
pp. 61-67
Author(s):  
Ahmed Al-Imam ◽  
Hend J. Al-Doori ◽  
Ali K. Al-Shalchy

Background: Common warts frequently occur over the hands and may overlie critical structures, including the extensor expansion of the digits, for which cryotherapy can lead to manual disability. Aims and Objectives: We aim to implement big data to infer knowledge on the interest of web users regarding the dorsal expansion-related manual disability in verrucae vulgaris patients managed with cryotherapy. Materials and Methods: We mapped the interest of users of the surface web in connection with five topics: cryosurgery, extensor digitorum muscle, human papillomavirus, manual disability, and verruca vulgaris. We retrieved longitudinal data [2004-2019] concerning the spatio-temporal variations of interest in these topics, using Google Trends. We are also reporting a case of interest while analyzing it using the Bradford Hill criteria. Results: Sixty-four nations contributed to the spatial (geographic) map, including ten countries from the Middle East and the north of Africa (15.63%). There was high temporal variability concerning cryosurgery 29.61 (+/- 0.94), extensor digitorum muscle 64.43 (+/- 0.86), human papillomavirus 0.01 (+/- 0.01), manual disability 2.89 (+/- 0.13), and verruca vulgaris 9.39 (+/- 0.20). Conjoint inference, via Post-Hoc testing and neural networks [machine learning], assigned the highest synaptic weight [effect size] to “cryosurgery” and “extensor digitorum muscle”, thus indicating that these topics are of prime interest for web users, including anatomists and dermatologists. Conclusions: We are conveying two messages: 1) Dermatologists are encouraged to collaborate with data scientists to realize the importance of big data for evidence-based dermatology. 2) Physicians should exercise extra caution in managing patients with verrucae vulgaris using cryotherapy. 

2009 ◽  
Vol 6 (2) ◽  
pp. 1655-1686
Author(s):  
A. M. Omar ◽  
A. Olsen ◽  
T. Johannessen ◽  
M. Hoppema ◽  
H. Thomas ◽  
...  

Abstract. Data from two Voluntary Observing Ship (VOS) (MS Trans Carrier and MV Nuka Arctica), acquired along one zonal and one meridional transect (2005–2007) augmented with data subsets from ten cruises (1987–2005) were used to investigate the spatio-temporal variations of the CO2 fugacity in seawater (fCO2sw) in the North Sea at seasonal and inter-annual time scales. The observed seasonal fCO2sw variations were related to variations in sea surface temperature (SST), biology plus mixing, and air-sea CO2 exchange. Over the study period, the seasonal amplitude in fCO2sw induced by SST changes was 0.4–0.75 times those resulting from variations in biology plus mixing. Along the meridional transect, fCO2sw normally decreased northwards (−12 μatm per degree latitude), but the gradient disappeared/reversed during spring as a consequence of an enhanced seasonal amplitude of fCO2sw in southern parts of the North Sea. Along the zonal transect, a weak gradient (−0.8 μatm per degree longitude) was observed in the mean annual fCO2sw. Annually and averaged over the study area, surface waters of the North Sea were CO2 undersaturated and thus a sink of atmospheric CO2 throughout the year. However, during summer, surface waters in the region 55.5–54.5° N were CO2 supersaturated and, hence, a source for atmospheric CO2. Comparison of fCO2sw data acquired within two 1°×1° regions in the northern and southern North Sea during different years (1987, 2001, 2002, and 2005–2007) revealed large interannual variations, especially during spring and summer when year-to-year fCO2sw differences (≈160–200 μatm) approached seasonal changes (≈200–250 μatm). The springtime variations resulted from changes in magnitude and timing of the phytoplankton bloom, whereas changes in SST, wind speed, and total alkalinity may have contributed to the summertime interannual fCO2sw differences. The lowest interannual variation (10–50 μatm) was observed during fall and early winter. The comparison with data reported in October 1967 suggests that the fCO2sw growth rate in the central North Sea is similar to that in the atmosphere.


2020 ◽  
Author(s):  
M. Korhan Erturac ◽  
Eren Şahiner ◽  
Azad Sağlam Selçuk ◽  
Alper Gürbüz ◽  
Hilal Okur ◽  
...  

<p>The study area (40-40.45°N and 30-32.15° E) exhibits a high topography (1200-1800 m elevation) and bounded by the Galatean Massif at east, Pontide Mountain Range to the north, the Central Anatolian Plateau to the south and the Marmara Sea to the west. The region is actively been deformed and dissected by the active branches of the dextral strike slip North Anatolian Fault Zone (NAFZ) and the Sakarya River (SR) system. We have investigated the depositional terraces formed along the main course and the major tributaries of the SR to reveal the dynamics of the terrace formation by climate, sea level changes and also to quantify the variations in rate of vertical deformation within the current geodynamics of the NW Anatolian Block. The geometry of the main river (1) and its tributaries (4) allow us to determine the spatio-temporal variations in four vertical (100 km) and three along fault sections (200 km) since the last ~150 ka.</p><p>Up to date, we have mapped 23 distinct evenly scattered multi-step terrace staircases along the main river course and its 6 major tributaries. Mapping is aided with high precision rtk-GPS profiling and SfM photogrammetry using UAV. The dating is carried by luminescence geochronology (OSL and p-IRIR) to constrain the timing of the formation and also abandonment of each depositional terrace step.</p><p>The results show that the focus region is under control of vertical deformation at a rate of 0.6-0.7 mm/year regardless from the distance to the main strand of the NAFZ. There is also evidence that this rate has been decelerated from ~1.0-1.1 mm/year since the last 100 ka. The distinct variations in the calculated uplift rates along the profiles reveal apperant southwards tilting in between the active branches of the NAFZ and also within the block.</p><p>This study is funded by TUBITAK 117Y426 project grant. </p>


2017 ◽  
Vol 208 ◽  
pp. 223-230 ◽  
Author(s):  
Hanène Belkahia ◽  
Mourad Ben Said ◽  
Narjesse El Mabrouk ◽  
Mariem Saidani ◽  
Chayma Cherni ◽  
...  

2014 ◽  
Vol 997 ◽  
pp. 843-846 ◽  
Author(s):  
Hao Liu ◽  
Xin Ming Tang ◽  
Wei Cao ◽  
Zhi Ying Xie ◽  
Jing Han Lei ◽  
...  

Based on the monthly data of MODIS Level 3, the spatio-temporal variabilities of Aerosol Optical Depth (AOD) over areas around Beijing have been analyzed from March 2000 to December 2013. The results presented that: (1) In the past 14 years , the annual mean AODs vary between 0.428 and 0.550; The recent 14 years can be divided into two stages, the first stage is 2000-2007, which shows an increasing trend with an increase rate of 1.349%, while the second stage is 2008-2013, which shows an decreasing trend with a decrease rate of 1.483%; Summer has the maximum AOD, but shows a decreasing trend, while winter has the minimum AOD, but shows an increasing trend. (2) AODs over the south are higher than the north, high AODs are mainly distributed along the southwest of Hebei and southwest of Shandong with an AOD of 0.72, while low AODs are mainly distributed along the north of Hebei and the north of Shanxi with an AOD of 0.23; The spatial distribution of AOD varies with the seasons, AODs are high in spring, and are maximized in summer, then show a significant decrease from summer to autumn, while are minimized in winter.


2010 ◽  
Vol 74 (5) ◽  
pp. 540-548 ◽  
Author(s):  
Carlos Lizárraga-Celaya ◽  
Christopher J. Watts ◽  
Julio C. Rodríguez ◽  
Jaime Garatuza-Payán ◽  
Russell L. Scott ◽  
...  

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