scholarly journals Swertia chirayita: The Himalayan Herb

2014 ◽  
Vol 2 (4) ◽  
pp. 389-392 ◽  
Author(s):  
Supreet Khanal ◽  
N. Shakya ◽  
N. Nepal ◽  
D. Pant
Keyword(s):  
Secondary Metabolites ◽  
Swertia Chirayita ◽  
Enteric Diseases ◽  
Sustainable Conservation ◽  
Swertia Species

Swertia chirayita is a native Himalayan herb typically found in the altitude of 1500 to 3100m. Swertia species are commonly used as primary medicines in fever, digestive and enteric diseases; especially S. chirayita is of principal importance. The pharmacological and ethno-medicinal perspective of the plant is well understood traditionally and pharmaceutically. Its secondary metabolites including glycosides and xanthones show promising bioactivity making it a powerful herb. Mixing of Swertia chirayita with its other species is done routinely in chiretta trade. Extensive wild collection and lack of sustainable conservation has led to the vulnerable status of the wild cultivar. DOI: http://dx.doi.org/10.3126/ijasbt.v2i4.11281 Int J Appl Sci Biotechnol, Vol. 2(4): 389-392

scholarly journals Trade and Sustainable Conservation of Swertia chirayita (Roxb. ex Fleming) h. Karst in Nepal

1970 ◽  
Vol 11 ◽  
pp. 125-132 ◽  
Author(s):  
Susanna Phoboo ◽  
Pramod Kumar Jha
Keyword(s):  
Medicinal Plant ◽  
Large Scale ◽  
Sustainable Use ◽  
Current Status ◽  
Fiscal Year ◽  
Sustainable Harvesting ◽  
Swertia Chirayita ◽  
Extensive Collection ◽  
Sustainable Conservation ◽  
Important Medicinal Plant

Swertia chirayita (Roxb. ex Fleming) H. Karst is one of the most important high-value medicinal plants of Nepal prized for its anti-diabetic, antimalarial, hepato-protective and anti-inflammatory properties. It is widely used as an important ingredient in medicinal preparations in Ayurveda, Unnani, Siddha, Tibetan and Chinese traditional medicine. Nepal is one of the main exporters of this important plant and the most significant importers are India and China. The large scale export of this plant has made it vulnerable in Nepal and there is an immediate need for its conservation. Detailed information on the current status of trade of this plant in Nepal is necessary to understand and make assumptions on its current market standing or future predictions of demand. S. chirayita is traded in 61 of the 75 districts of Nepal and constituted about 3% in the total medicinal plant traded in the fiscal year 2008-2009. Due to extensive collection of S. chirayita from the wild, there is a need for exploring alternative conservation options in order to preserve the remaining wild population. Sustainable harvesting and cultivation can help in its conservation. This paper briefly reviews the state of trade and sustainable conservation of this important medicinal plant in Nepal. Key words: Swertia chirayita; trade; cultivation; sustainable use; sustainable harvesting DOI: 10.3126/njst.v11i0.4134Nepal Journal of Science and Technology 11 (2010) 125-132

scholarly journals Identification of Secondary Metabolites and Proximate Analysis of Golden Apple Snails (Pomacea canaliculata L.) Meat Extract

2021 ◽  
Vol 22 (2) ◽  
pp. 101
Author(s):  
Meilisha Putri Pertiwi ◽  
Dina Dyah Saputri
Keyword(s):  
Secondary Metabolites ◽  
Animal Feed ◽  
Proximate Analysis ◽  
Pomacea Canaliculata ◽  
Nutritional Content ◽  
Meat Extract ◽  
Feed Manufacturing ◽  
Sustainable Conservation ◽  
Golden Apples ◽  
Hand Sorting

The growth of golden apple snails is very rapid and causes losses of paddy production. Therefore snails are also called pest, especially agricultural pest. Control of golden apple snails can be done by physical hand sorting and then processed into animal feed. Based on research golden apple snails proven have good nutritional content. Efforts to use golden apples nails pets become useful things such as animal feed is a sustainable conservation. Therefore, this study aims to carry out secondary metabolites identification, proximate testing, and antioxidant content of golden apple snails as an initial reference for the basic ingredients of animal feed manufacturing. The method use is hand sorting of golden apple snails at the research location, then brought to the laboratory to carry out the process of secondary metabolites identification, proximate testing, and antioxidant analysis. The results showed a golden apple snails (Pomacea canaliculata L.) extract containing active compunds of alkaloids, flavonoids, tannins and polyphenols, steroids, and glycoside. Proximate analysis showed that golden apple snails extract had a high protein content of 40,83% compared to carbohydrates and fats. These findings suggested that golden apple snailsmeat extract has the potential to be further utilized as an alternative feed for Pangasius sp.Keywords: golden apple snails. Pangasius sp., proximate testing, secondary metabolites.

In vitro organogenesis secondary metabolite production and heavy metal analysis in Swertia chirayita

2014 ◽  
Vol 9 (7) ◽  
pp. 686-698 ◽  
Author(s):  
Vijay Kumar ◽  
Shailesh Singh ◽  
Rajib Bandopadhyay ◽  
Madan Sharma ◽  
Sheela Chandra
Keyword(s):  
Heavy Metal ◽  
Secondary Metabolites ◽  
Secondary Metabolite ◽  
Leaf Explants ◽  
Secondary Metabolite Production ◽  
Direct Organogenesis ◽  
Metabolite Production ◽  
Swertia Chirayita

AbstractAn efficient protocol of plant regeneration through direct and indirect organogenesis in Swertia chirayita was developed. Explants cultured on Murashige and Skoog medium supplemented with 2,4-D (0.5 mg L−1) with combination of Kinetin (0.5 mg L−1) showed the highest frequency (84%) of callusing and 1.0mg L−1 6-benzyladenine (BA) in combination with (100 mg L−1) Adenine sulphate (Ads) + (0.1 mg L−1) Indole acetic acid (IAA) was excellent for maximum adventitious shoot (12.69 ± 1.30) formation in four week of culture. A maximum number of (7.14 ± 0.99) shoots were developed per leaf explants through direct organogenesis. The highest frequency of rooting (11.46 ± 1.56) was observed on MS medium augmented with IAA (1.0 mg L−1). Well-rooted shoots transferred to plastic pots containing a soilrite: sand mix and then moved to the greenhouse for further growth and development. Four major secondary metabolites were analyzed and quantified using high performance liquid chromatography. Amount of secondary metabolites was found significantly higher, in in vitro plantlets compared to in vivo plantlets and callus raised from S. chirayita. Higher heavy metal accumulation in in vitro as compared to in vivo plantlets correlates higher secondary metabolite production supporting that they play regulatory role in influencing the plant secondary metabolism.

Phytochemistry and Pharmacological Activities of the Genus Swertia (Gentianaceae): A Review

2017 ◽  
Vol 45 (04) ◽  
pp. 667-736 ◽  
Author(s):  
Jie Li ◽  
Yan-Li Zhao ◽  
Heng-Yu Huang ◽  
Yuan-Zhong Wang
Keyword(s):  
Secondary Metabolites ◽  
Biosynthetic Pathway ◽  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Reverse Transcriptases ◽  
Cns Depressant ◽  
Anti Oxidant ◽  
Broad Variety ◽  
Multiple Ligands ◽  
Swertia Species

Swertia plants have been considered to be medicinal plants useful for the treatment of various ailments for thousands of years, especially in Asian countries. This is due to the broad variety of chemical compounds that provide multiple ligands for bonding to different endogenous biomacromolecules for patients. Chemical constituents and pharmacological activities of Swertia plants are summarized in this paper. Approximately 419 metabolites and 40 bioactive compounds have been reported from 30 Swertia species, including xanthones, flavonoids, seco-iridiods, iridiods, triterpenoids, alkaloids, volatiles, and other secondary metabolites. The bioactivities of Swertia plants include anticarcinogenic, hepatoprotective, anti-oxidant, hypoglycemic, anthelmintic, antibacterial, antifungal, anti-diabetic, gut, and airways modulatory, metabolizing isozymes inhibitory, neuroprotective, HIV-I reverse transcriptases inhibitory, anticholinergic, and CNS-depressant activities, etc. In addition, biosynthetic pathways of xanthones, and seco-iridiods, two most important secondary metabolites for Swertia, are elucidated. The xanthones biosynthetic pathway is a mixed biosynthetic pathway involved the shikimate and the malonate routes, and the seco-iridoid pathway starts with geraniol derived from IPP which is produced either via the MEP or the MVA pathway. This review will offer a reference for future researches on the protection of natural resources, the investigation of therapeutic basis, new drug development, and so forth. Metabolic pathways of some crucial active compounds were also discussed in this review.

scholarly journals Anti-diabetic potential of crude extracts of medicinal plants used as substitutes for Swertia chirayita using in vitro assays

1970 ◽  
Vol 7 ◽  
pp. 48-55 ◽  
Author(s):  
Susanna Phoboo ◽  
Prasanta C Bhowmik ◽  
Pramod Kumar Jha ◽  
Kalidas Shetty
Keyword(s):  
Type 2 Diabetes ◽  
Antioxidant Activity ◽  
Early Stage ◽  
Andrographis Paniculata ◽  
Total Phenolic ◽  
Swertia Chirayita ◽  
Inhibitory Potential ◽  
Swertia Species

Swertia chirayita is a highly traded medicinal plant of Nepal widely used for its anti-diabetic potential. In this study, two herbs (Swertia nervosa and Andrographis paniculata) often used as adulterants and substitutes of Swertia chirayita were analyzed for their antioxidant activity, α-glucosidase inhibitory potential and total phenolic content and compared with that of Swertia chirayita. Aqueous and 12% ethanolic extracts of the three herbs showed moderate to high antioxidant activity and moderate α-glucosidase inhibitory potential. HPLC/ DAD revealed the presence of swertiamarin and mangiferin in all the Swertia species, while Andrographis paniculata contained cinnamates such as cinnamic acid, p-coumaric acid and chlorogenic acid. The antioxidant activity and α-glucosidase inhibitory potential was evident in the two herbs indicating their relevance as substitutes for Swertia chirayita for potential early stage management of type-2 diabetes and related complications. Key-words: Andrographis paniculata; antioxidant activity; cinnamates; mangiferin; Swertia nervosa; swertiamarin; α-glucosidase; type-2 diabetes. DOI: 10.3126/botor.v7i0.4373Botanica Orientalis – Journal of Plant Science (2010) 7: 48-55

Lycopene alleviates sulfamethoxazole-induced hepatotoxicity in grass carp (Ctenopharyngodon idellus) via suppression of oxidative stress, inflammation and apoptosis

2020 ◽  
Vol 11 (10) ◽  
pp. 8547-8559
Author(s):  
Hongjing Zhao ◽  
Yu Wang ◽  
Mengyao Mu ◽  
Menghao Guo ◽  
Hongxian Yu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Secondary Metabolites ◽  
Human Health ◽  
Grass Carp ◽  
Aquatic Environment ◽  
Ctenopharyngodon Idellus

Antibiotics are used worldwide to treat diseases in humans and other animals; most of them and their secondary metabolites are discharged into the aquatic environment, posing a serious threat to human health.

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