scholarly journals Study of thyroid volume by ultrasonography in clinically euthyroid patients

1970 ◽  
Vol 32 (2) ◽  
pp. 36-43 ◽  
Author(s):  
P Kayastha ◽  
S Paudel ◽  
DM Shrestha ◽  
RJ Ghimire ◽  
S Pradhan

Introduction: The purpose of this study was to establish reference ranges of total thyroid volume among clinically euthyroid Nepalese population using Ultrasonography and correlate this volume with age, sex, individual’s built and geographic location. Methods: This was a prospective cross sectional study involving 485 clinically euthyroid individuals. B - mode Ultrasonography was used to measure the total thyroid volume by combining the volume of both the lobes obtained by using formula for prolate ellipsoid. Age specific reference values for thyroid volume were obtained and Pearson correlation test was used to see the relationship with various factors. Results: Among 485 individuals between 1 to 83 years of age, 221(45.57%) were males and 264(54.43%) were females. Maximum [354 individuals (72.99%)] were from hilly region and minimum [16 individual (3.30%)] were from Himalayan region. Mean thyroid volume was 6.629 ± 2.5025 ml. In general, thyroid volume was found to be more in older individuals than in young age group. There was no significant difference of thyroid volume between males and females. Thyroid volume best correlated with body surface area (r=0.444, p<0.0001). The volume had a positive correlation with weight (r=0.443, p<0.0001), body mass index (r=0.371, p<0.0001) and height (r=0.320, p<0.0001) of the individual. Conclusions: This study estimated the reference range of total thyroid volume for Nepalese population. These ranges are significantly lower than the WHO/ICCIDD thyroid volume references and reference values obtained in various other countries. Total thyroid volume best correlated with Body surface area. Keywords: Body surface area; clinically euthyroid; total thyroid volume; ultrasonography DOI: http://dx.doi.org/10.3126/joim.v32i2.4944 Journal of Institute of Medicine, August, 2010; 32: 36-43

2021 ◽  
Vol 12 ◽  
Author(s):  
Yingying Wang ◽  
Xiaolian Dong ◽  
Chaowei Fu ◽  
Meifang Su ◽  
Feng Jiang ◽  
...  

BackgroundThyroid volume (Tvol) is associated with many factors, but the current reference values for Tvol in children with sufficient iodine intake are inappropriate and need to be updated. Moderate changes in thyroid morphology and accentuated increases in body fat percentage occur during puberty as an adaption of the body and sexual development occurs. This study aimed to evaluate the influences of physical growth on Tvol and propose an easily applicable method for conducting Tvol assessments in pubertal girls with sufficient iodine intake.MethodsA cohort study was conducted on 481 pubertal girls in East China from 2017 to 2019. B-ultrasound was used to assess Tvol. Multiple linear regression models were used to estimate the associations of Tvol enlargement (dTvol) with changes in height (dH), weight (dW), waist circumference (dW), body mass index (dBMI), and body surface area (dBSA). Thyroid volume indexes (TVIs), including height thyroid volume index (HVI), weight and height thyroid volume index (WHVI), body mass index thyroid index (BMIV), and body surface area thyroid index (BSAV), were calculated to explore an appropriate method for Tvol assessments by Spearman correlation analyses.ResultsTvol, height, weight, BMI, and BSA increased significantly from baseline to follow-up (P&lt;0.001). The associations between dTvol and physical growth were only observed in the 13 to 14-year-old group. dH, dW,dBMI, and dBSA were positively related to dTvol, with the maximum β of 5.74 (95%CI: 2.54 to 8.94) on dBSA, while dWC was negatively related to dTvol (β= -0.05, 95%CI: -0.08 to -0.03). Both dHVI and dBSAV were not associated with dH, dW, dBMI, or dBSA in both age groups (P&gt;0.05).ConclusionsThyroid volume was associated with physical growth in pubertal girls in East China, both age and anthropometric measurements must be comprehensively considered to establish the reference values for Tvol. HVI, and BSAV may be better indicators for Tvol assessments in pubertal girls.


2017 ◽  
Vol 5 ◽  
Author(s):  
Karen Karimi ◽  
Iris Faraklas ◽  
Giavonni Lewis ◽  
Daniel Ha ◽  
Bridget Walker ◽  
...  

Abstract Background There is increasing evidence that sex differences may influence responses after thermal injury and affect clinical outcomes. The objective of this study was to evaluate the relationships between sex, thermal injury, body size, and inpatient mortality in burn patients. Methods Medical records of adults with &gt;20% total body surface area (TBSA) burn injury admitted to two American Burn Association (ABA)-verified burn centers between 2008 and 2014 were retrospectively reviewed. Injury details and baseline characteristics, including body size as estimated by body surface area (BSA) and body mass index (BMI) were recorded, along with details of the hospital course. The primary outcome of inpatient mortality was compared between sexes. Results Out of 334 subjects, 60 were women (18%). Median TBSA was 33% (IQR 25–49) in this cohort, with 19% full thickness burns and 30% inhalation injury. Despite no significant difference in age, presence of inhalation injury, TBSA, or depth of burn, women had significantly higher rates of inpatient mortality (45 vs. 29%, P = 0.01). BSA was significantly lower in women vs. men (P &lt; 0.001), but this difference was not more pronounced among non-survivors. There was no difference in BMI between men and women non-survivors. Although not significant (P = 0.28), women succumbed to their injuries sooner than men (day 4 vs. 10 post-injury). Conclusions Women are less likely to survive burn injuries and die sooner than men with similar injuries. Body size does not appear to modulate this effect. Burn centers should be aware of the higher mortality risk in women with large burns.


2015 ◽  
Vol 4 (1) ◽  
pp. 55-61 ◽  
Author(s):  
Silvia Turcios ◽  
Juan J. Lence-Anta ◽  
Jose-Luis Santana ◽  
Celia M. Pereda ◽  
Milagros Velasco ◽  
...  

Objectives: The aim of this study was to describe the thyroid volume in healthy adults by ultrasound and to correlate this volume with some anthropometric measures and other differentiated thyroid cancer risk factors. Study Design: Thyroid volume and anthropometric measures were recorded in a sample of 100 healthy adults, including 21 men and 79 women aged 18-50 years, living in a non-iodine-deficient area of Havana city. Results: The average thyroid volume was 6.6 ± 0.26 ml; it was higher in men (7.3 ml) than in women (6.4 ml; p = 0.15). In the univariate analysis, thyroid volume was correlated with all anthropometric measures, but in the multivariate analysis, body surface area was found to be the only significant anthropometric parameter. Thyroid volume was also higher in current or former smokers and in persons with blood group AB or B. Conclusion: Specific reference values of thyroid volume as a function of body surface area could be used for evaluating thyroid volume in clinical practice. The relation between body surface area and thyroid volume is coherent with what is known about the relation of thyroid volume to thyroid cancer risk, but the same is not true about the relation between thyroid volume and smoking habit.


Author(s):  
Niek H. Prakken ◽  
Birgitta K. Velthuis ◽  
Arco J. Teske ◽  
Arend Mosterd ◽  
Willem P. Mali ◽  
...  

2019 ◽  
Vol 5 (1) ◽  
pp. e000488 ◽  
Author(s):  
Katherine M Edenfield ◽  
Fred Reifsteck ◽  
Stephen Carek ◽  
Kimberly G Harmon ◽  
Breton M Asken ◽  
...  

BackgroundAre borderline echocardiogram structural measurements due to physiological adaptation or pathology in college football players? The normal reference data are very limited in this population. We report left ventricular end-diastolic diameter (LVEDD) and interventricular septal diameter (IVSD) echocardiogram findings in college football athletes.Methods and resultsA retrospective cohort review of preparticipation examination transthoracic echocardiogram measurements of LVEDD and IVSD from 375 American collegiate football athletes cleared for participation from the University of Florida in 2012–2017 and University of Georgia in 2010–2015 was performed.LVEDD and IVSD were analysed by field position (lineman, n=137; non-lineman, n=238), race (black, n=216; white, n=158) and body surface area (BSA) for associations. Values were compared with non-athlete norms, and collegiate football athlete-specific reference norm tables were created.Twenty-one (5.6%) athletes had LVEDD and 116 (31%) had IVSD measurements above the reference normal non-athlete values. Univariate analyses indicated that the lineman position and increasing BSA were associated with larger values for LVEDD and IVSD. Black race was associated with larger IVSD values, and white race was associated with larger LVEDD values. Player position correlated strongly with BSA (r>0.7); we created normal reference tables for LVEDD and IVSD, stratified by BSA group classification (low, average and high BSA). Proposed clinical cut-offs for normal and abnormal values are reported for raw echocardiograph metrics and BSA-indexed scores.ConclusionsA significant number of collegiate football athletes had LVEDD and IVSD values above non-athlete norms. BSA-specific normal values help clinicians interpret results for football athletes.


1961 ◽  
Vol 16 (6) ◽  
pp. 969-970 ◽  
Author(s):  
Sachchidananda Banerjee ◽  
Ashim Kumar Bhattacharya

Body surface area (BSA) was actually measured in 13 Indian Hindu children, of ages varying between 3 and 12 yr, with tape and surface integrator. In 9 out of 13 children the results obtained were lower than the BSA calculated with the weight-height formula of Du Bois and Du Bois. Based on the actual measurements, a new constant for the weight-height formula was obtained and a new equation: surface area, cm2 = weight 0.425 kg x height 0.725 cm x 70, has been suggested for the BSA of Indian children. A nomogram for reading off surface area in metric units based on the above formula was prepared. A significant difference existed between the BSA calculated with the new formula and that of Du Bois and Du Bois. Submitted on December 30, 1960


PEDIATRICS ◽  
1963 ◽  
Vol 32 (2) ◽  
pp. 186-201
Author(s):  
Glen G. Cayler ◽  
Abraham M. Rudolph ◽  
Alexander S. Nadas

A technique for measuring cardiac output by the Fick method in small infants during cardiac catheterization is described. Data on resting oxygen consumption, arteriovenous oxygen difference and systemic cardiac output is presented for a group of 126 subjects composed mainly of infants and young children with congenital heart disease. It was found that (a) there was no significant difference in mean resting cardiac index for patients with body surface area under 1.0 square meter regardless of the presence of, or the severity of, heart disease, and (b) patients with heart disease who were larger than 1.0 square meter had significantly lower mean cardiac indices and higher arteriovenous oxygen differences than the control patients. An excellent linear correlation of cardiac output to body surface area was found. There was also a close correlation between index and regression lines for cardiac output leading support to the validity of the cardiac index concept for comparing cardiac outputs in various sized patients. The normal increase in cardiac output during exercise is greater for children than for adults. Forty-seven per cent (8 of 17) children with heart disease showed low cardiac output response to exercise.


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