scholarly journals Paroxysmal Neuralgia in Pediatric Population- A Diagnostic Dilemma for Physicians and Dental Practioners

2014 ◽  
Vol 10 (4) ◽  
pp. 74-77 ◽  
Author(s):  
A Dubey ◽  
S Mujoo ◽  
SB Sakarde ◽  
AK Dubey
Keyword(s):  
Neuropathic Pain ◽  
Orofacial Pain ◽  
Pediatric Population ◽  
Treatment Strategies ◽  
Diagnostic Dilemma ◽  
Dental Pathology ◽  
Dental Intervention

Paroxysmal neuralgia is relatively uncommon in children. Neuropathic orofacial pain is a challenge for the clinician, as no obvious dental pathology exists either clinically or radiographically. Dentist and physician should be able to recognize the characteristics of neuropathic pain so as to correctly diagnose these conditions hence avoid unnecessary dental intervention. This article reviews the conditions with paroxysmal neuralgia in children and available treatment strategies. DOI: http://dx.doi.org/10.3126/kumj.v10i4.11000 Kathmandu Univ Med J 2012;10(4):74-77

Cranial neuralgias and persistent idiopathic facial pain

2020 ◽  
pp. 237-247
Author(s):  
Aydin Gozalov ◽  
Messoud Ashina ◽  
Joanna M. Zakrzewska
Keyword(s):  
Neuropathic Pain ◽  
Trigeminal Neuralgia ◽  
Facial Pain ◽  
Orofacial Pain ◽  
Treatment Modalities ◽  
Management Approach ◽  
Trigeminal Neuropathy ◽  
Facial Region ◽  
Persistent Idiopathic Facial Pain ◽  
Chronic Orofacial Pain

Orofacial pain is a complex problem and affects up to 7% of the population. Although trigeminal neuralgia has been considered the prime neuralgic condition in the facial region, other forms of neuropathic pain are now being more frequently recognized and require recognition and a different management approach. Many patients with chronic orofacial pain report numerous comorbidities, such as psychiatric or personality disorders, which significantly affect management. Various pain conditions present in the facial region. Some of them rarely present extra-orally (unless as radiating pain) such as atypical odontalgia or persistent dento-alveolar pain disorder and burning mouth syndrome, whereas others will present in both areas such as classical trigeminal neuralgia, post-traumatic trigeminal neuropathy, trigeminal neuropathy attributed to multiple sclerosis, and persistent idiopathic facial pain. Myofascial pain syndrome related to the muscles of mastication is very common and may also be associated with temporomandibular joint problems. Trigeminal neuralgia and the rarer glossopharyngeal neuralgia are similar in quality and characteristics with specific treatment modalities, but differ in pain location. Trigeminal neuropathic pain is caused most frequently by trauma. If no other diagnostic criteria are fulfilled, a diagnosis of persistent idiopathic facial pain is made. It is crucial for these patients to be managed by multidisciplinary teams.

scholarly journals Diagnostic Dilemma of Recurrent Pulmonary Embolism

Diagnostics ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 96
Author(s):  
Alexandra Dadarlat-Pop ◽  
Irina Burian ◽  
Laura Cadis ◽  
Raluca Tomoaia ◽  
Alexandru Oprea
Keyword(s):  
Pulmonary Embolism ◽  
Rare Case ◽  
Treatment Strategies ◽  
Venous Aneurysm ◽  
Magnetic Resonance Examination ◽  
Diagnostic Dilemma ◽  
Popliteal Aneurysm ◽  
Patch Angioplasty ◽  
Recurrent Pulmonary Embolism ◽  
Point Compression

Popliteal venous aneurysms are rare vascular disorders associated with a high risk of pulmonary embolism. We present the case of a 56-year-old woman hospitalized for a third episode of unprovoked pulmonary embolism. Venous ultrasonography identified a popliteal aneurysm, repeatedly missed by two-point compression venous ultrasonography, which was eventually confirmed by a magnetic resonance examination. Because of its highly symptomatic nature despite optimal anticoagulant treatment, the decision was made to undergo surgery, consisting of aneurysmectomy followed by patch angioplasty. The goal of this paper is to report a rare case of popliteal venous aneurysm and its treatment strategies and postoperative evolution.

Incorporating Immunotherapy Into the Treatment Strategies of B-Cell Adult Acute Lymphoblastic Leukemia: The Role of Blinatumomab and Inotuzumab Ozogamicin

2018 ◽  
pp. 574-578 ◽  
Author(s):  
Hagop Kantarjian ◽  
Elias Jabbour
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Pediatric Population ◽  
Lymphoblastic Leukemia ◽  
Treatment Strategies ◽  
Clinical Activity ◽  
Inotuzumab Ozogamicin ◽  
Term Survival ◽  
Drug Conjugates ◽  
Cure Rates

Monoclonal antibodies and bispecific antibody constructs hold considerable promise in improving the outcomes of patients with acute lymphoblastic leukemia (ALL). Antibody-drug conjugates such as inotuzumab ozogamicin and the bispecific T-cell engager blinatumomab represent novel antibody constructs that have shown substantial clinical activity in ALL. Although most studies have focused on the use of these agents in the salvage setting, incorporation of these antibodies into the frontline regimens is imperative to improve long-term survival for patients with ALL and to increase the cure rates of adult ALL to the levels achieved in the pediatric population.

Alternative treatment strategies for neuropathic pain: Role of Indian medicinal plants and compounds of plant origin-A review

2017 ◽  
Vol 92 ◽  
pp. 634-650 ◽  
Author(s):  
Hasandeep Singh ◽  
Sakshi Bhushan ◽  
Rohit Arora ◽  
Harpal Singh Buttar ◽  
Saroj Arora ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Medicinal Plants ◽  
Alternative Treatment ◽  
Treatment Strategies ◽  
Plant Origin ◽  
Indian Medicinal Plants

scholarly journals Neonatal Acute Paronychia

Hand ◽  
2017 ◽  
Vol 12 (5) ◽  
pp. NP99-NP100 ◽  
Author(s):  
Luke Grome ◽  
Gregory Borah
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Pediatric Population ◽  
Treatment Strategies ◽  
Initial Therapy ◽  
Age Group ◽  
Predisposing Factor ◽  
Incision And Drainage ◽  
Amoxicillin Clavulanate ◽  
Neonatal Patient

Background: Paronychia is defined as infection afflicting the eponychial nail folds of the hand or foot. Such infections are rarely reported in the perinatal age group, and not previously described in a neonate younger than 2 weeks. Trauma resulting in inoculation of the nail fold is the most common predisposing factor to paronychia. Oral trauma in the pediatric population from finger sucking predisposes this population to a different set of bacterial pathogens than adults. Contamination can progress to infection and abscess formation within the nail fold with the most prevalent vector in adult infections being Staphylococcus aureus. Comparatively, mixed anaerobic and aerobic infections tend to afflict children with oral soothing habits. Methods: This is a case report will present the rare occurrence of a paronychia in a neonate caused by methicillin-resistant Staphylococcus aureus. Results: The management and treatment strategies for paronychia in this atypical neonatal patient consisted of incision and drainage and antibiotic therapy. Conclusion: Neonates with oral self-soothing behaviors may be more at risk for developing paronychia of mixed anaerobic and aerobic infections. Initial therapy with broad-spectrum antibiotics amoxicillin/clavulanate or clindamycin is suggested. Incision and drainage in the perinatal setting coupled with antibiotics is curative.

Neuropathic Pain Scale Base Rate for Orofacial Pain Population

2007 ◽  
Vol 103 (6) ◽  
pp. 795
Author(s):  
S.J. Scrivani ◽  
R.J. Kulich ◽  
N. Bindayel ◽  
B. Chandwani ◽  
N.R. Mehta
Keyword(s):  
Neuropathic Pain ◽  
Orofacial Pain ◽  
Pain Scale ◽  
Base Rate

scholarly journals Orofacial pain: basic mechanisms and implication for successful management

2003 ◽  
Vol 11 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Paulo César Rodrigues Conti ◽  
Richard A. Pertes ◽  
Gary M. Heir ◽  
Cibele Nasri ◽  
Harold V. Cohen ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Temporomandibular Disorders ◽  
Facial Pain ◽  
Orofacial Pain ◽  
Dental Pain ◽  
Medical Problem ◽  
Basic Knowledge ◽  
Successful Management ◽  
Long Period ◽  
The Status

Orofacial Pain is the field of dentistry devoted to the diagnosis and management of chronic, complex, facial pain and oromotor disorders. This specialty in dentistry has developed over a number of years out of the need for better understanding of a group of patients who somehow were not clearly suffering from dental pain disorders, but still did not seem to have a clearly defined medical problem. After a long period of treating patients based on the mechanicist aspect of the disease, our profession has realized the importance of basic knowledge and differencial diagnosis in order to proper manage these patients. This modification in the approach has caused severe changes in education as well as in clinical activities. Historically considered as a problem of occlusion, Orofacial Pain, including Temporomandibular Disorders (TMD) has recently reached the status of "Specialty" in Brazil. Therefore, this paper aims to discuss the main differences between musculoskeletal and neuropathic pain and the importance of basic knowledge to perform successful management.

scholarly journals Comparative effectiveness of treatment strategies for severe splenic trauma in the pediatric population

2016 ◽  
Vol 212 (4) ◽  
pp. 786-793 ◽  
Author(s):  
Kristy L. Rialon ◽  
Brian R. Englum ◽  
Brian C. Gulack ◽  
Carlos J. Guevara ◽  
Syamal D. Bhattacharya ◽  
...  
Keyword(s):  
Comparative Effectiveness ◽  
Pediatric Population ◽  
Treatment Strategies ◽  
Splenic Trauma

scholarly journals How I diagnose and treat splenic lymphomas

Blood ◽  
2011 ◽  
Vol 117 (9) ◽  
pp. 2585-2595 ◽  
Author(s):  
Emilio Iannitto ◽  
Claudio Tripodo
Keyword(s):  
Clinical Laboratory ◽  
Incidental Finding ◽  
Treatment Strategies ◽  
Systemic Diseases ◽  
Clinical Heterogeneity ◽  
Diagnostic Dilemma ◽  
Clinical Behavior ◽  
Lymphoid Malignancies ◽  
Pathologic Features ◽  
High Degree

Abstract The incidental finding of an isolated splenomegaly during clinical assessment of patients evaluated for unrelated causes has become increasingly frequent because of the widespread use of imaging. Therefore, the challenging approach to the differential diagnosis of spleen disorders has emerged as a rather common issue of clinical practice. A true diagnostic dilemma hides in distinguishing pathologic conditions primarily involving the spleen from those in which splenomegaly presents as an epiphenomenon of hepatic or systemic diseases. Among the causes of isolated splenomegaly, lymphoid malignancies account for a relevant, yet probably underestimated, number of cases. Splenic lymphomas constitute a wide and heterogeneous array of diseases, whose clinical behavior spans from indolent to highly aggressive. Such a clinical heterogeneity is paralleled by the high degree of biologic variation in the lymphoid populations from which they originate. Nevertheless, the presenting clinical, laboratory, and pathologic features of these diseases often display significant overlaps. In this manuscript, we present our approach to the diagnosis and treatment of these rare lymphomas, whose complexity has been so far determined by the lack of prospectively validated prognostic systems, treatment strategies, and response criteria.

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