scholarly journals Unusual variation in musculocutaneous nerves

1970 ◽  
Vol 7 (4) ◽  
pp. 408-410 ◽  
Author(s):  
C Bhattarai ◽  
PP Poudel
Keyword(s):  
Peripheral Nerve ◽  
Clinical Investigation ◽  
Nerve Repair ◽  
Clinical Importance ◽  
Anatomical Variations ◽  
Musculocutaneous Nerve ◽  
Branching Pattern ◽  
Variational Study ◽  
The Right ◽  
Nerve System

Background: Variations in origin, course, branching pattern, termination and connections of the musculocutaneous nerve in the arm are not as uncommon as was once thought. Variational study of nerve in Nepalese is very less and can be of surigical-clinical importance. This opinion led us to performing this study. Objectives: The aim of this study was to a study in Nepalese which could be important for clinical investigation and the surgical treatment of peripheral nerve injury. Materials and methods: This study was carried out in Manipal College of medical sciences (MCOMS). Dissection of formalised 16 cadavers (n=32 upper limbs) were carried out using normal dissection kit with the help of standard dissection manual in two and half years. Results: The study revealed the variation in course, branching pattern and termination of musculocutaneous nerve in 6.25% of cases unilaterally on the right side. No statistically significant differences by gender and side were observed. Conclusion: This present study provides the evidence of variation of musculocutaneous nerve in Nepalese. The knowledge of the anatomical variations of the peripheral nerve system can help explain an incomprehensible clinical sign. Key words: Musculocutaneous nerve; Median nerve; Brachial plexus; Peripheral nerve repair. DOI: 10.3126/kumj.v7i4.2763 Kathmandu University Medical Journal (2009) Vol.7, No.4 Issue 28, 408-410

scholarly journals Anatomical Variations of the Recurrent Laryngeal Nerve and Implications for Injury Prevention during Surgical Procedures of the Neck

Diagnostics ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 670
Author(s):  
Alison M. Thomas ◽  
Daniel K. Fahim ◽  
Jickssa M. Gemechu
Keyword(s):  
Recurrent Laryngeal Nerve ◽  
Surgical Procedures ◽  
Anatomical Variations ◽  
Laryngeal Nerve ◽  
Inferior Thyroid Artery ◽  
Branching Pattern ◽  
The Right ◽  
Relationship Of ◽  
Intrinsic Laryngeal Muscles ◽  
Formalin Fixed

Accurate knowledge of anatomical variations of the recurrent laryngeal nerve (RLN) provides information to prevent inadvertent intraoperative injury and ultimately guide best clinical and surgical practices. The present study aims to assess the potential anatomical variability of RLN pertaining to its course, branching pattern, and relationship to the inferior thyroid artery, which makes it vulnerable during surgical procedures of the neck. Fifty-five formalin-fixed cadavers were carefully dissected and examined, with the course of the RLN carefully evaluated and documented bilaterally. Our findings indicate that extra-laryngeal branches coming off the RLN on both the right and left side innervate the esophagus, trachea, and mainly intrinsic laryngeal muscles. On the right side, 89.1% of the cadavers demonstrated 2–5 extra-laryngeal branches. On the left, 74.6% of the cadavers demonstrated 2–3 extra-laryngeal branches. In relation to the inferior thyroid artery (ITA), 67.9% of right RLNs were located anteriorly, while 32.1% were located posteriorly. On the other hand, 32.1% of left RLNs were anterior to the ITA, while 67.9% were related posteriorly. On both sides, 3–5% of RLN crossed in between the branches of the ITA. Anatomical consideration of the variations in the course, branching pattern, and relationship of the RLNs is essential to minimize complications associated with surgical procedures of the neck, especially thyroidectomy and anterior cervical discectomy and fusion (ACDF) surgery. The information gained in this study emphasizes the need to preferentially utilize left-sided approaches for ACDF surgery whenever possible.

scholarly journals Unilateral high division of brachial artery

2016 ◽  
Vol 05 (02) ◽  
pp. 266-272
Author(s):  
T. M. Sucharitha ◽  
L. Hema ◽  
S. V. Phanindra
Keyword(s):  
Upper Limb ◽  
Brachial Artery ◽  
Clinical Importance ◽  
Branching Pattern ◽  
Invasive Procedures ◽  
Arterial Variations ◽  
Female Cadaver ◽  
Variation Patterns ◽  
Cubital Fossa ◽  
The Right

AbstractArterial variations in the arm are of great clinical importance as this area is commonly involved in many surgical and invasive procedures. During dissection, we observed in the right upper limb a variation in the division and branching pattern of brachial artery in a female cadaver. The short segmented brachial artery divided about 6 cms. above the line joining the epicondyles of the humerus, but not in the cubital fossa. The course of the two divisions in the forearm is normal. Knowledge of these variation patterns is useful during surgeries.

scholarly journals Variations in the course and branching pattern of musculocutaneous nerve

2013 ◽  
Vol 02 (04) ◽  
pp. 195-199
Author(s):  
Amar Jayanthi A. ◽  
Arunkumar K G.
Keyword(s):  
Median Nerve ◽  
Growth Cone ◽  
Single Case ◽  
Clinical Importance ◽  
Anatomical Variations ◽  
Musculocutaneous Nerve ◽  
Axonal Pathfinding ◽  
Chi Square ◽  
Medical College ◽  
Chi Square Test

Abstract Background and aim: The variations in the course and communicating branches of musculocutaneous nerve is of clinical importance in the treatment of recurrent compression neuropathies and in the diagnosis of median nerve lesions. Most of the reports on anatomical variations of musculocutaneous nerve are single case studies and such studies with emphasis on gender difference in a sample of Keralite population are rarely reported. The objective of the present study is to observe the variations in the course of musculocutaneous nerve with special reference to communications with other nerves of the arm and to study the correlation between gender and variations of the nerve. Materials and Methods: Two hundred and sixty four arms were dissected in the department of Anatomy, Government medical college, Thrissur and studied for variations of muculocutaneous nerve. Analysis was done with epi info, using proportions, confidence interval and Chi Square test. The communications noted were classified using the available classifications of Le Minor, Venieratos and Anagnostopoulou and Choi et al. Results: Nerve variations were seen in 24.2 % cases which include, absence of the nerve (3.4%), nerve not piercing coracobrachialis (12.4%) and communication to median nerve (15.1 %). All the variations observed were statistically not significant. The embryological basis for the axonal pathfinding is considered as a result of both guidance molecules and electrical activity that change the calcium homeostasis within the growth cone to regulate growth cone turning. Conclusion: Variations that were observed in the present study may give sufficient and relevant data on the nerves, among Keralite population in which studies are few.

scholarly journals Cadaveric Study of Anatomical Variations in the Musculocutaneous Nerve and in the Median Nerve

2019 ◽  
Vol 36 (02) ◽  
pp. 122-125
Author(s):  
Abhilasha Priya ◽  
Chandni Gupta ◽  
Antony Sylvan D'souza
Keyword(s):  
Brachial Plexus ◽  
Median Nerve ◽  
Peripheral Nerves ◽  
Anatomical Variations ◽  
Musculocutaneous Nerve ◽  
Branching Pattern ◽  
Kasturba Medical College ◽  
Upper Limbs ◽  
Medical College ◽  
Lateral Cord

Introduction The musculocutaneous nerve and the median nerve are branches from the lateral cord of the brachial plexus with a root value of C5, C6, and C7. The medial root of the median nerve is a branch of the medial cord. The present study aims at observing any variations in these peripheral nerves, so that this knowledge can be utilized by surgeons, anesthesiologists, and orthopedicians during surgical procedures and nerve block. Materials and Methods The present study was carried on 30 adult embalmed cadavers (60 upper limbs) in the department of anatomy of the Kasturba Medical College , Manipal, India. The infraclavicular part of the brachial plexus was dissected, and any anatomical variations in the formation and in the branching pattern of the musculocutaneous nerve and of the median nerve were noted and photographs were taken. Results The median nerve was noted to be formed from 3 roots in 8 out of 60 dissected upper limbs (13.33%). The musculocutaneous nerve was absent in 5% of the dissected limbs, and communications between these 2 nerves were noted in 13.33% of the dissected limbs. Conclusions Noted variations of the nerves may be of help to surgeons operating in the axillas and in the arms.

scholarly journals Study on Curvatures of Clavicle With Its Clinical Importance

2012 ◽  
Vol 9 (4) ◽  
pp. 279-282 ◽  
Author(s):  
M K Haque ◽  
D I Mansur ◽  
K Sharma
Keyword(s):  
Intramedullary Nailing ◽  
Total Curvature ◽  
Clinical Importance ◽  
Anatomical Variations ◽  
First Year ◽  
Medical Sciences ◽  
Human Skeleton ◽  
Left Clavicle ◽  
Lateral Curvature ◽  
The Right

Background The clavicle is the most frequently fractured bone of the human skeleton. 70–80% of fractures occur at the middle third of the shaft of the bone. Anatomical variations in the clavicle of relevance to form intramedullary fixation. Objectives The purpose of this study was attempted to know about comparative differences between curvatures of the right and left clavicles, from certain metrical parameters. Methods The materials for the present study consisted of 257 (135 right and 122 left) adult clavicles, which were collected from the Department of Anatomy and from the students of the first year M.B.B.S during the period 2010 - 2011, Department of Anatomy, Kathmandu University School of Medical Sciences, Dhulikhel, Nepal. The deepest points of the curvatures of the clavicle, where the convexities were the maximum. These angles were measured with the help of a protractor. The sum of the two angles constituted the total curvature of the bone. Results The average medial angle, lateral angle and sum of the two angles of right side were 150.97º ±6.16 SD, 139.76º ±7.55 SD and 290.73º ±11.14 respectively and that of the left side were 151.50º ±5.67SD, 141.73º ±8.44 SD and 293.23º ±11.69SD respectively. The present study revealed that the medial and lateral angles of the left clavicle were greater than that of the right clavicle and medial curvature was more than the lateral curvature of the same clavicle. Conclusions It is important to recognize anatomical variations in the curvatures of clavicle when considering intramedullary nailing techniques. It also helps Anthropologists in their study of evolution.DOI: http://dx.doi.org/10.3126/kumj.v9i4.6344 Kathmandu Univ Med J 2011;9(4):279-82

scholarly journals Variation in the branching pattern of celiac trunk: a case report

2015 ◽  
Vol 32 (03) ◽  
pp. 200-202
Author(s):  
S. Nayak ◽  
A. Aithal ◽  
S. Shetty ◽  
N. Kumar ◽  
S. Ravindra ◽  
...  
Keyword(s):  
Hepatic Artery ◽  
Celiac Trunk ◽  
Anatomical Variations ◽  
Left Gastric Artery ◽  
Branching Pattern ◽  
Gastric Artery ◽  
Current Case ◽  
Hepatic Arteries ◽  
The People ◽  
The Right

AbstractArterial supply for the derivatives of foregut in the abdomen is provided by the branches of the celiac trunk. Celiac trunk is the first ventral branch of abdominal aorta and usually branches into splenic, common hepatic and left gastric arteries. Variations in the branching pattern of celiac trunk are common but in most of the people, they remain asymptomatic and go unnoticed. A good knowledge of these anatomical variations is important for surgeons undertaking various surgeries in the abdominal region and will help to minimise the complications related to abdominal surgery. Clinicians and radiologists should also be aware of any variations in the vascular pattern of the celiac trunk before performing angiographic examinations. In the current case, the celiac trunk divided into two branches; left gastric artery and hepato-splenic trunk. The hepato-splenic trunk further divided into splenic and common hepatic arteries. The common hepatic artery trifitrcated into proper hepatic, gastroduodenal and accessory hepatic arteries. Hepatic artery proper divided into right and left hepatic arteries. The accessory hepatic artery was tortuous and was as large as the left hepatic artery. It gave origin to the right gastric artery and entered the liver through left end of porta hepatis.

scholarly journals MicroRNA Mediated Regulation of Schwann Cell Migration and Proliferation in Peripheral Nerve Injury

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Eun Jung Sohn ◽  
Hwan Tae Park
Keyword(s):  
Peripheral Nerve ◽  
Nerve Injury ◽  
Peripheral Nerves ◽  
Peripheral Nerve Injury ◽  
Nerve Repair ◽  
Noncoding Rnas ◽  
Potential Therapeutic Target ◽  
Neuronal Disease ◽  
Cell Migration And Proliferation ◽  
Nerve System

Schwann cells (SCs) contribute to nerve repair following injury; however, the underlying molecular mechanism is poorly understood. MicroRNAs (miRNAs), which are short noncoding RNAs, have been shown to play a role in neuronal disease. In this work, we show that miRNAs regulate the peripheral nerve system by modulating the migration and proliferation of SCs. Thus, miRNAs expressed in peripheral nerves may provide a potential therapeutic target for peripheral nerve injury or repair.

The Branching Pattern and Communications of the Musculocutaneous Nerve

2007 ◽  
Vol 32 (5) ◽  
pp. 560-562 ◽  
Author(s):  
A. KRISHNAMURTHY ◽  
S. R. NAYAK ◽  
L. VENKATRAYA PRABHU ◽  
R. P. HEGDE ◽  
S. SURENDRAN ◽  
...  
Keyword(s):  
Median Nerve ◽  
Peripheral Nerves ◽  
Anatomical Variation ◽  
Anatomical Variations ◽  
Clinical Findings ◽  
Musculocutaneous Nerve ◽  
Branching Pattern ◽  
Upper Limbs ◽  
Lateral Aspect ◽  
Upper Arm

Anatomical variations of peripheral nerves are important and can help explain otherwise incomprehensible clinical findings. A study of 26 right and 18 left formalin-preserved upper limbs identified the fact that the musculocutaneous nerve is subject to considerable anatomical variation, including communication with the median nerve. A study of its branching pattern made us aware of why debility after trauma to the lateral aspect of the upper arm may be more than expected, and this study considers the clinical and surgical importance of these variations of the musculocutaneous nerve.

scholarly journals Obestatin signaling controls Schwann cells and axonal transport to counteract neuromuscular synaptic loss in skeletal muscle

2020 ◽  
Author(s):  
Jesus P Camiña ◽  
Agustín Sánchez-Temprano ◽  
Saúl Leal-López ◽  
Jessica González-Sánchez ◽  
Carlos S. Mosteiro ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Peripheral Nerve ◽  
Schwann Cells ◽  
Nerve Injury ◽  
Nerve Repair ◽  
Axon Growth ◽  
Neuromuscular Synapses ◽  
Axonal Regrowth ◽  
Peripheral Nerve System ◽  
Nerve System

Abstract Background. Injuries to the peripheral nerve system are common conditions, with broad spectrum of symptoms depending on the impaired nerves and severity of damage. Although peripheral nervous system retains a remarkable ability for regeneration, it is estimated that less than ten percent of patients fully recover function after nerve injury and the available treatments remain suboptimal. Here, we identify a role for the obestatin/GPR39 system in the regulation of the Schwann cell plasticity as well as in the preservation of neuromuscular synapses in the course of nerve repair. Methods. Utilizing a compression model of sciatic nerve injury, axonotmesis, we assessed the obestatin-related regenerative response in the peripheral nerve system. The role of the obestatin/GPR39 system was further evaluated on immortalized rat Schwann cells, IFRS1, and the model of neuronal differentiation, PC12 cells. The interactions between SCs and neurons was evaluated using a co-culture system that combine the SC cell line IFRS1 and the NGF-primed PC12. Results. Obestatin signaling directs proliferation and migration of Schwann cells that sustain axonal regrowth and later remyelinate regenerated axons. We provide evidence supporting the preservation of skeletal muscle by the maintenance of neuromuscular synapses through the axonal regulation of calpain-calpastatin proteolytic system. This encompasses the control of skeletal muscle homeostasis by regulation of the ubiquitin proteasome system and the autophagy machinery. Conclusions. These results provide important insights into how the obestatin/GPR39 system promotes nerve repair through integration of multiple molecular cues of neuron-Schwann cells crosstalk aimed to promote axon growth and guide axons back to their targets.

scholarly journals VARIATIONS IN THE BRANCHING PATTERN OF THE INTERNAL ILIAC ARTERY IN AN ADULT MALE – A CASE REPORT. Variaciones en el patrón de ramificación de la arteria ilíaca interna en un varón adulto: informe de un caso

2016 ◽  
Vol 4 (1) ◽  
pp. 25-28
Author(s):  
Satheesha Nayak B ◽  
Srinivasa Rao Sirasanagandla ◽  
Narendra Pamidi ◽  
Raghu Jetti
Keyword(s):  
Iliac Artery ◽  
Internal Iliac Artery ◽  
Clinical Importance ◽  
Branching Pattern ◽  
Obturator Artery ◽  
Cadaveric Specimen ◽  
Internal Iliac ◽  
Posterior Division ◽  
Anterior Division ◽  
The Right

Variaciones en el patrón de ramificación de la arteria ilíaca interna son ocasionalmente encontradas en las disecciones cadavéricas y las cirugías. Algunas de las variaciones son de importancia quirúrgica y clínica e ignorarlas podría derivar en alarmantes sangrados durante las prácticas quirúrgicas. Evaluamos las variantes en el patrón de la arteria ilíaca interna en un cadáver masculino. La división de la arteria ilíaca interna dio origen a las arterias rectal media y obturatriz. La arteria vesical superior tenía su origen en la arteria obturatriz. La división posterior de la arteria ilíaca interna dio lugar a las arterias iliolumbar, sacra lateral, glútea superior y pudenda interna. La arteria glútea inferior estaba ausente. Variations in the branching pattern of the internal iliac artery are occasionally encountered during cadaveric dissections and surgeries. Some of the variations are of surgical and clinical importance and ignoring them might result in alarming bleeding during surgical procedures. We report variant branching pattern of the right internal iliac artery in a male cadaveric specimen. The anterior division of the internal iliac artery gave origin to obturator and middle rectal arteries. Superior vesical artery took its origin from the obturator artery. The posterior division of the internal iliac artery gave iliolumbar, lateral sacral, superior gluteal and internal pudendal arteries. The inferior gluteal artery was absent.

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