scholarly journals Epidemiology and laboratory diagnosis of fungal corneal ulcer in the Sundarban Region of West Bengal, eastern India

1970 ◽  
Vol 4 (1) ◽  
pp. 29-36 ◽  
Author(s):  
S Bandyopadhyay ◽  
D Das ◽  
KK Mondal ◽  
AK Ghanta ◽  
SK Purkait ◽  
...  
Keyword(s):  
West Bengal ◽  
Corneal Ulcer ◽  
Tertiary Care ◽  
Laboratory Diagnosis ◽  
Microbial Culture ◽  
Care Hospital ◽  
Eastern India ◽  
Corneal Ulcers ◽  
Epidemiological Characteristics ◽  
Culture Positive

Introduction: Corneal ulcers are the second most-common cause of preventable blindness after cataract in tropical developing countries. Fungal corneal ulcers constitute 30 to 62 % of the total microbial culture-positive corneal ulcers. Objective: To study the epidemiological characteristics, risk factors and laboratory diagnosis of fungal corneal ulcer in the Sundarban Region, West Bengal, eastern India. Materials and methods: A retrospective review of 399 culture-positive, fungal corneal ulcers out of a total 928 corneal ulcer patients attending a tertiary care hospital in Kolkata, eastern India, over a period of four years from February 2007 to January 2011. Results: Males (246; 61.65 %) were more commonly affected than females (P < .0001). The affected people were mostly (342; 85.71 %) residing in the rural areas (P < .0001). 196 patients (49.12 %) were involved in agricultural activities (P < .0001). The younger people of, 21 - 50 years of age, were particularly prone to this disease (269; 67.41 %). Corneal trauma (354; 88.72 %) was the commonest risk factor (P < .0001) and 261 patients (61.41 %) had a history of trauma with vegetative matter (P< .0001). The use of topical corticosteroids was implicated in 65 (16.29 %) cases. The incidence of the disease was highest in the monsoon season, between June to September (192; 48.12 %). The aspergillus spp was the most common fungal growth (151; 37.84 %), followed by an Fusarium spp (81; 20.3 %). Conclusion: The fungal corneal ulcers are an important cause of ocular morbidity in people residing in the Sundarban Region. The identification of the etiology and the predisposing factors of corneal ulcers in this region are important for the prevention and early treatment of the disease. DOI: http://dx.doi.org/10.3126/nepjoph.v4i1.5847 NEPJOPH 2012; 4(1): 29-36

scholarly journals Study of keratomycosis at a tertiary care teaching hospital

2021 ◽  
Vol 7 (2) ◽  
pp. 65-70
Author(s):  
Veluri Gayathri ◽  
Ami Jeswin
Keyword(s):  
Corneal Ulcer ◽  
Fusarium Species ◽  
Tertiary Care ◽  
Fungal Keratitis ◽  
Care Hospital ◽  
Predisposing Factor ◽  
Corneal Ulcers ◽  
Detection And Identification ◽  
Bacterial Aetiology ◽  
A Prospective Study

Corneal infections are one of the leading causes of ocular morbidity and blindness world-wide. If normal defence mechanisms of the eye are compromised, almost any microorganism can invade the cornea. It is important to know the exact aetiology of corneal ulcer to institute appropriate therapy in time, least serious consequences may follow.  To isolate and identify the fungi from corneal scrapings of suspected keratitis patients. A prospective study of Fungal keratitis was conducted at Al-Azhar Medical College & Super Speciality Hospital in Thodupuzha, Kerala a tertiary care hospital with a capacity of 650 beds. The duration of the study was two years from January 2018 to January 2020. Patients with suspected fungal corneal ulcers presenting in the Out-Patient Department (OPD) of Ophthalmology were investigated for fungal etiology in the Department of Microbiology were included in this study. Each patient was examined with slit lamp. Data collected from history given by patient and patient examination. Using standard techniques. The specimens collected were then smeared on two slides, which were stained with Gram stain (for bacterial keratitis) and 10% potassium hydroxide preparation (for fungal keratitis) studied under light microscope. Of the 866 patients with corneal ulcer investigated, 83 cases with fungal and 36 with bacterial aetiology was identified. Males were more commonly affected and were mostly in the age group of 31-40 year. It was seen that trauma was the most common predisposing factor especially in the agriculturists and the farmers. Among the identified fungi, most were hyaline. Of the 83 positive specimens, the most frequent agent isolated was Fusarium species in 31 (37.3%) cases. 23 (27.7%) was the second most common followed by , ., . Candida albicans were 5 (6%) followed by 1 (1.2%). Fungal Keratitis is a serious problem usually following corneal trauma, it requires rapid detection and identification of fugal agents for treatment to prevent disastrous consequences.

scholarly journals Calcium carbide related ocular burn injuries during mango ripening season of West Bengal, eastern India

2013 ◽  
Vol 5 (2) ◽  
pp. 242-245 ◽  
Author(s):  
Sabyasachi Bandyopadhyay ◽  
M Saha ◽  
S Biswas ◽  
A Ranjan ◽  
AK Naskar ◽  
...  
Keyword(s):  
West Bengal ◽  
Burn Injury ◽  
Tertiary Care ◽  
Calcium Carbide ◽  
Visual Outcome ◽  
Burn Injuries ◽  
Care Hospital ◽  
Eastern India ◽  
Visual Disability ◽  
Open Globe

Introduction: Calcium carbide used in fruit ripening industry as a cheap alternative to natural plant hormone ethylene produces highly inflammable acetylene gas. Inadvertent ignition of this gas can cause severe ocular burn injury with unilateral or bilateral blindness. Objective: To determine the characteristics and visual outcome of ocular burn injuries from calcium carbide during mango ripening season of West Bengal, eastern India. Materials and methods: A prospective study of all cases of calcium carbide related ocular burn injury attending a tertiary care hospital during mango ripening season was carried out. The demographic features, characteristics of the injury, management and outcomes were recorded. Results: Fifty five eyes of 33 patients were studied. Males were more commonly affected (20 patients, 60.6%) than females. The injury was bilateral in 22 patients (66.66%). Seventeen patients (51.51%) were below 20 years of age. Ten eyes had open globe injuries and 45 eyes had closed globe injuries. One eye of a patient had to be enucleated (3%). Children below 14 years of age were mainly injured while playing with indigenous fireworks of shooting carbide. Middle aged women were affected particularly during ignition of evening lamps. Carbide lamp was another source of injury. Conclusion: Males are more commonly affected by calcium carbide related ocular injuries. Children and young adults are the common victims. Such injuries can involve both the eyes and cause a permanent visual disability. Nepal J Ophthalmol 2013; 5(10): 242-245 DOI: http://dx.doi.org/10.3126/nepjoph.v5i2.8736

scholarly journals IS THERE A CORRELATION BETWEEN THE OUTCOME OF REFERRED SICK NEONATES AND PERIPHERAL UTILIZATION OF RESOURCES DURING TRANSPORT? EVIDENCE FROM THE NICU OF A TERTIARY CARE HOSPITAL OF EASTERN INDIA USING TOPS SCORE

2020 ◽  
pp. 1-3
Author(s):  
Sandip Sen
Keyword(s):  
Supportive Care ◽  
West Bengal ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Eastern India ◽  
New Born ◽  
Post Graduate Institute ◽  
Two Parameters ◽  
Training Modules

BACKGROUND: This study was conducted at the NICU of Dr B C Roy Post Graduate Institute of Paediatric Sciences, a tertiary care children's hospital in Kolkata, West Bengal, India, to study the immediate outcome of the referred sick neonates and peripheral utilization of resources before and during transport. METHODOLOGY: Aprospective observational study on 250 new born babies referred to Dr. B. C. Roy Post-Graduation Institute of Paediatric Sciences, Kolkata, India during the period of June 2016 to May 2017. At the admission detailed clinical assessment of the baby has been done and clinical physiological parameters (TOPS- Temperature, Oxygenation (Airway & Breathing), Perfusion, Sugar) were recorded. Pre transport TOPS and transport TOPS were noted. The babies were followed up for the next seventy two hours to study the correlation between the utilization of the resources and immediate outcome of the babies in terms of death, cardiorespiratory support (mechanical ventilation, CPAP, inotrope therapy), supportive care and discharge within next 72 hours. RESULTS: Out of 250 babies, 62% were boys, 58.4% were pre term,65% were low birth weight. 60% were transported in government ambulance. 100% mortality was present in babies taking > 2 hrs to reach the hospital. 44 babies had no alteration of TOPS parameters while one parameter was affected in 115 babies (46%), two parameters were affected in 51 babies (20.4%), three parameters were affected in 30 babies (12%) and all four parameters were affected in 10 babies (10%). Hypothermia was present in 65%, hypoxia in 34.8%, hypoperfusion in 23% and hypoglycemia in 16%. 44.8% were discharged with in 72 hours, 23.6% received supportive care, 17.2% required cardio-respiratory support and 14.4% died. CONCLUSION: Emphasis on stabilization of sick new born before and during transfer should be done. Training modules to all the personnel involved in the care of a sick new born and regular practise of the same should be encouraged. In-utero transport by identifying the high-risk pregnancies is beter way to decrease the requirement of transport should be supplied. Longer duration of transportation has a high mortality

scholarly journals A Study on Microbial Profile of Corneal Ulcer Cases in a Tertiary Health Care Centre of Southern Assam

2021 ◽  
Vol 8 (7) ◽  
pp. 228-235
Author(s):  
Barnamoy Bhattacharjee ◽  
Atanu Chakravarty
Keyword(s):  
Corneal Ulcer ◽  
Fusarium Species ◽  
Tertiary Care ◽  
Agricultural Practice ◽  
Care Hospital ◽  
Corneal Ulceration ◽  
Penicillium Species ◽  
Direct Microscopy ◽  
Corneal Ulcers ◽  
Microbial Profile

Background-Visual impairment due to corneal ulceration has for long been acknowledged as leading cause of blindness both worldwide and in India only next to Cataract. The aetiology for infective corneal ulcer varies considerably with occupation of patients in different regions of India. Thus, continuing with empirical management without lab diagnosis leads to protracted clinical course. So, understanding the microbial profile of corneal ulcers in agriculture dependent population of Southern Assam helps in improved management of this morbidity. Aims- To 1) Find the prevalence of infected corneal ulcers in untreated patients attending Ophthalmology department of a tertiary care hospital of Southern Assam. 2) Study the pattern of microbial aetiology in the infected corneal ulcer cases. 3) Find the association of infected corneal ulcers with various attributing factors. Method-Corneal scrapings from 86 routine untreated cases of corneal ulceration from Ophthalmology Department were studied prospectively from Dec2017 to Jan2019 and subjected to Gram staining and direct examination with 10%KOH. Culture on SDA and Blood Agar were incubated at 25°C and 37°C respectively and followed up for 3 weeks before declaring sterile. Antimicrobial sensitivity was performed for bacterial isolate and yeast-like species. Slide culture and LPCB tease mount were done for identification of moulds. Result- Out of the 86 cases, 58 were positive in direct microscopy, of which 44 were culture positive. Of the 28 samples negative in direct microscopy, 2 were positive by Culture. Bacterial isolates were found in 5 cases and fungal aetiology in 41 cases. Conclusion- The prevalence of infected corneal ulcer as per standard of Culture positivity is 53.5% (46/86). Mycotic involvement was found in 90% cases. Important fungal isolates identified were Aspergillus species, Penicillium species, Curvularia species, Fusarium species, Sarocladium species. Higher prevalence was significantly associated with harvesting season, agricultural practice and history of trauma while diabetes and steroid intake were not significantly associated with mycotic ulcers. Keywords: Corneal ulcer, Assam, Fungal, Fusarium, Sarocladium, Pseudomonas.

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