scholarly journals Osteoporosis, Rasio Kalsium dan RASIO ASUPAN KALSIUM DAN ASUPAN FOSFOR SERTA AKTIVITAS FISIK TERKAIT NILAI BONE MASS DENSITY (BMD) PADA LANSIA OSTEOPOROSIS

Author(s):  
Ardiani Listianingrum

Provinsi Jawa Timur memiliki risiko osteoporosis tertinggi sebesar 21,42% (Prasetya dkk, 2015). Kepadatan tulang dipengaruhi faktor genetik, jenis kelamin, status gizi, asupan zat gizi (kalsium dan fosfor) dan gaya hidup seperti aktivitas fisik, merokok, konsumsi kafein dan alkohol yang berlebihan. (Janice LT, 2008). Tujuan penelitian ini adalah diketahuinya rasio asupan kalsium dan asupan fosfor serta aktivitas fisik terkait nilai bone mass density (BMD) pada lansia osteoporosis. Desain penelitian yang digunakan yaitu descriptive observasional. Penelitian ini dilaksanakan pada bulan April 2018 di Poli Lansia RSIA Puri Malang dengan 32 subyek penelitian. Analisis yang digunakan adalah analisis deskriptif kualitatif. Berdasarkan hasil analisis didapatkan asupan kalsium pada lansia terdapat 32 responden (100%) termasuk kategori defisit tingkat berat. Rata-rata asupan kalsium responden yaitu 474,8 mg. Sedangkan asupan fosfor pada lansia terdapat 16 responden (50%) termasuk kategori diatas AKG. Rata-rata asupan fosfor responden yaitu 890,6 mg. Kesesuaian rasio asupan kalsium dan fosfor terdapat 2 responden (6,25%) dengan kesesuaian rasio ≤ 1,5. Pada aktivitas fisik terdapat 16 responden (50%) memiliki kategori aktifitas fisik sedang dan 16 responden (50%) kategori aktifitas fisik ringan. Hal ini menunjukkan bahwa semakin rendah nilai Bone Mass Density (BMD) yaitu <-3,0 maka aktivitas fisik yang dilakukan oleh responden semakin ringan. Sedangkan semakin rendahnya nilai Bone Mass Density (BMD) yaitu <3,0 maka rasio asupan kalsium dan fosfor responden semakin tinggi. Perlu dilakukan upaya pencegahan terjadinya osteoporosis pada pasien lansia yaitu dengan pemberian edukasi untuk merubah pengetahuan pasien mengenai pentingnya pengaturan asupan makanan terutama asupan kalsium dan fosfor serta aktivitas fisik.

Author(s):  
Maximilian J. Hartel ◽  
Tareq Naji ◽  
Florian Fensky ◽  
Frank O. Henes ◽  
Darius M. Thiesen ◽  
...  

Abstract Purpose To investigate the range of indications of an anatomical-preshaped three-dimensional suprapectineal plate and to assess the impact of the bone mass density on radiologic outcomes in different types of acetabular fractures. Patients and methods A consecutive case series of 50 acetabular fractures (patient age 69 ± 23 years) treated with suprapectineal anatomic plates were analyzed in a retrospective study. The analysis included: Mechanism of injury, fracture pattern, surgical approach, need for additional total hip arthroplasty, intra- or postoperative complications, as well as bone mass density and radiological outcome on postoperative computed tomography. Results Most frequently, anterior column fracture patterns with and without hemitransverse components as well as associated two column fractures were encountered. The anterior intrapelvic approach (AIP) was used in 98% (49/50) of the cases as primary approach with additional utilization of the first window of the ilioinguinal approach in 13/50 cases (26%). Determination of bone density revealed impaired bone quality in 70% (31/44). Postoperative steps and gaps were significantly greater in this subgroup (p < 0.05). Fracture reduction quality for postoperative steps revealed anatomic results in 92% if the bone quality was normal and in 46% if impaired (p < 0.05). In seven cases (14%), the plate was utilized in combination with acute primary arthroplasty. Conclusion A preshaped suprapectineal plate provides good radiological outcomes in a variety of indications in a predominantly geriatric cohort. Impaired bone quality has a significantly higher risk of poor reduction results. In cases with extensive joint destruction, the combination with total hip arthroplasty was a valuable option.


2001 ◽  
Vol 31 (8) ◽  
pp. 731-735 ◽  
Author(s):  
G. E. Piérard ◽  
C. Piérard-Franchimont ◽  
S. Vanderplaetsen ◽  
N. Franchimont ◽  
U. Gaspard ◽  
...  

Bone ◽  
2011 ◽  
Vol 49 (2) ◽  
pp. 257-263 ◽  
Author(s):  
Nicola Napoli ◽  
Claudio Pedone ◽  
Paolo Pozzilli ◽  
Fulvio Lauretani ◽  
Stefania Bandinelli ◽  
...  

2015 ◽  
Vol 227 (3) ◽  
pp. 129-141 ◽  
Author(s):  
Russell T Turner ◽  
Michael Dube ◽  
Adam J Branscum ◽  
Carmen P Wong ◽  
Dawn A Olson ◽  
...  

Excessive weight gain in adults is associated with a variety of negative health outcomes. Unfortunately, dieting, exercise, and pharmacological interventions have had limited long-term success in weight control and can result in detrimental side effects, including accelerating age-related cancellous bone loss. We investigated the efficacy of using hypothalamic leptin gene therapy as an alternative method for reducing weight in skeletally-mature (9 months old) female rats and determined the impact of leptin-induced weight loss on bone mass, density, and microarchitecture, and serum biomarkers of bone turnover (CTx and osteocalcin). Rats were implanted with cannulae in the 3rd ventricle of the hypothalamus and injected with either recombinant adeno-associated virus encoding the gene for rat leptin (rAAV-Leptin,n=7) or a control vector encoding green fluorescent protein (rAAV-GFP,n=10) and sacrificed 18 weeks later. A baseline control group (n=7) was sacrificed at vector administration. rAAV-Leptin-treated rats lost weight (−4±2%) while rAAV-GFP-treated rats gained weight (14±2%) during the study. At study termination, rAAV-Leptin-treated rats weighed 17% less than rAAV-GFP-treated rats and had lower abdominal white adipose tissue weight (−80%), serum leptin (−77%), and serum IGF1 (−34%). Cancellous bone volume fraction in distal femur metaphysis and epiphysis, and in lumbar vertebra tended to be lower (P<0.1) in rAAV-GFP-treated rats (13.5 months old) compared to baseline control rats (9 months old). Significant differences in cancellous bone or biomarkers of bone turnover were not detected between rAAV-Leptin and rAAV-GFP rats. In summary, rAAV-Leptin-treated rats maintained a lower body weight compared to baseline and rAAV-GFP-treated rats with minimal effects on bone mass, density, microarchitecture, or biochemical markers of bone turnover.


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