scholarly journals Prevention of pregnancy and sickness after a sustained method of conservative myomectomy

2018 ◽  
Vol 22 (1) ◽  
pp. 152-155
Author(s):  
O.V. Golyanovskyy ◽  
M.A. Budchenko
Keyword(s):  
Argon Plasma Coagulation ◽  
Recovery Period ◽  
Argon Plasma ◽  
Reproductive Function ◽  
Reproductive Age ◽  
Complex Method ◽  
Synthetic Analogue ◽  
Fetal Head ◽  
Adhesion Barrier ◽  
Surgical Interventions

The number of surgical interventions in the uterus, including conservative myomectomy in women of reproductive age, has increased significantly, and, accordingly, the percentage of patients with a scar on the uterus has increased. It is difficult for women to make a pregnancy plan, to determine the best way and time of delivery. After the performed myomectomy, pregnancy planning is required not earlier than 6 months after the operation (provided the normal state of health and absence of complications). The peculiarity of the course of pregnancy after myomectomy is the presence of scarring on the uterus, and the importance of the volume and nature of the operation performed. Childbirth through natural birth lines can be resolved by specialists in the following cases: in the absence of exacerbations in the recovery period; if laboratory-instrumental studies confirm the fact of the fullness of the lower segment of the uterus; at placental placenta outside the scar tissue of the uterus; when the mother's pelvis matches the fetal head; with obligatory tracking of childbirth process using monitors; if possible, a cesarean section urgently, but not later than fifteen minutes after the decision to intervene. We proposed innovative approach is conservative myomectomy performed using electrosurgical techniques (argon plasma coagulation and radio wave scalpel) and such medications as Terlipressin (synthetic analogue of vasopressin), Defensal (anti-adhesion barrier). The conducted clinical research has determined the effectiveness of the complex method of surgical treatment of uterine leiomyomas with the use of modern drugs and technical support for the improvement of reproductive function in treated women.

scholarly journals Current trends in the pharmacotherapy of uterine myoma, associated with heavy menstrual bleeding and anemia: review

2020 ◽  
Author(s):  
Z. V. Revazova ◽  
L. V. Adamyan ◽  
O. N. Loginova ◽  
L. M. Manukyan ◽  
K. N. Arslanyan
Keyword(s):  
Uterine Fibroids ◽  
Reproductive Function ◽  
Uterine Myoma ◽  
Reproductive Age ◽  
Heavy Menstrual Bleeding ◽  
Menstrual Bleeding ◽  
Cochrane Library ◽  
Pharmacological Agents ◽  
Surgical Interventions ◽  
Current Trends

Aim: to summarize results of up-to-date world researches on the current trends of symptomatic myoma treatment.Materials and Мethods. A search of publications was carried out in the main international databases in Russian and English languages: PubMed/MEDLINE, The Cochrane Library, Embase, eLibrary. The analysis included studies published over the past 10 years examining the clinical efficacy and safety of various groups of pharmacological agents for the treatment of uterine myoma combined with heavy menstrual bleeding in women of reproductive age.Results. Currently, the treatment of uterine fibroids is divided into three main methods: surgical, minimally invasive organ-preserving methods, and pharmacotherapy. Until now, surgical intervention remains the main method of treatment, and, unfortunately, is often carried out in the volume of hysterectomy. However, today it is important to have a personalized approach to the management of a patient with symptomatic uterine myoma, taking into account her desire to preserve reproductive function. The development of the possibilities of drug therapy made a great contribution to the optimization of managing such patients.Conclusion. The global trend is to decrease the number of radical interventions, as well as the development and improvement of new methods of treating symptomatic uterine fibroids. Currently, pharmacotherapy of leiomyoma can significantly improve the quality of life of patients, reduce radical surgical interventions, optimize surgical treatment, and in certain situations, completely eliminate the need for surgery.

scholarly journals Modern approaches to the treatment of urogenital disorders in perimenopausal women

2020 ◽  
pp. 114-118
Author(s):  
L.V. Potapova ◽  
◽  
I.N. Shcherbina ◽  
Keyword(s):  
Malignant Tumors ◽  
Reproductive Function ◽  
Reproductive Age ◽  
Menstrual Disorders ◽  
Surgical Interventions ◽  
The Past ◽  
Perimenopausal Women ◽  
The Common ◽  
Systemic Nature

In modern gynecology, hormone-dependent pathology is one of the most significant problems. The importance of solving this problem is due to the significant prevalence of this pathology, its long-term recurrent course and the presence of a medico-social task of preserving the reproductive function of patients. The age of women who develop dyshormonal diseases is already 30–35 years old, which leads to premature loss of reproductive function, an increase in the frequency of surgical interventions. The systemic nature of the lesion in dyshormonal pathology is due to the common links of pathogenesis. The leading factor in the pathogenesis of hormone-dependent pathology is absolute or relative hyperestrogenism. Menstrual disorders (MD) is one of the most overlooked problems in modern gynecology. Over the past decade, an increase in the frequency of MD in women of reproductive age has been noted in the world by almost 11 times. In the structure of gynecological morbidity, according to most authors, MD s account for about 60% of all dyshormonal disorders, which often lead to an underestimation of future not only reproductive, but also general somatic problems: from miscarriage and infertility to the formation of both benign and malignant tumors in the female organism. Keywords: hormone-dependent pathology, menstrual disorders, estrogens, progesterone, treatment, indole-3-carbinol, rod extract, Agidol.

Ovarian endometriosis associated infertility: a modern view to the problem

GYNECOLOGY ◽  
2020 ◽  
Vol 22 (5) ◽  
pp. 44-49
Author(s):  
Mekan R. Orazov ◽  
Marina B. Khamoshina ◽  
Marianna Z. Abitova ◽  
Lyudmila M. Mikhaleva ◽  
Snezhana V. Volkova ◽  
...  
Keyword(s):  
Ovarian Reserve ◽  
Assisted Reproductive Technologies ◽  
Negative Impact ◽  
Ovarian Tissue ◽  
Reproductive Function ◽  
Reproductive Technologies ◽  
Reproductive Age ◽  
Ovarian Endometriosis ◽  
Surgical Interventions ◽  
Ovarian Endometriomas

This review summarizes current understanding of the pathogenesis of one of the most common forms of external genital endometriosis ovarian endometriomas. Due to their frequent occurrence in young women of reproductive age and extremely negative impact on the morphophysiological state of the ovaries, this disease makes a significant contribution to the structure of endometriosis-associated infertility. The main determinant of the negative effect of ovarian endometriomas on reproductive function is a decrease in ovarian reserve, which can occur either due to the direct gonadotoxic effect of the endometriod cyst itself, or due to the unintentional removal of healthy ovarian tissue during surgery or the use of aggressive methods of electrosurgery. Hence, the question of methods for achieving hemostasis during surgery in terms of iatrogenic effects on healthy ovarian tissue is debatable. The management strategy for patients with infertility associated with ovarian endometriosis consists of two components: surgical treatment and/or the use of assisted reproductive technologies. Laparoscopic cystectomy is indicated for cysts larger than 3 cm. Repeated surgical interventions in case of endometriosis do not improve fertility outcomes. Assisted reproductive technologies methods should be considered as a priority tactic in patients of older reproductive age with low ovarian reserve indicators or infertility duration of more than 2 years, as well as in cases of recurrent ovarian endometriomas. Management of such patients must be personalized and take into account the age, state of the ovarian reserve, duration of infertility, stage and number of surgical interventions for this disease.

Effective pharmacotherapeutic effect of indole-3-carbinol and rod extract as part of the drug Agidol

2020 ◽  
pp. 107-113
Author(s):  
T.V. Skritskaya ◽  
Keyword(s):  
Malignant Tumors ◽  
Reproductive Function ◽  
Reproductive Age ◽  
Menstrual Disorders ◽  
Women Of Reproductive Age ◽  
Surgical Interventions ◽  
The Past ◽  
The Common ◽  
Systemic Nature

In modern gynecology, hormone-dependent pathology is one of the most significant problems. The importance of solving this problem is due to the significant prevalence of this pathology, its long-term recurrent course and the presence of a medico-social task of preserving the reproductive function of patients. The age of women who develop dyshormonal diseases is already 30–35 years old, which leads to premature loss of reproductive function, an increase in the frequency of surgical interventions. The systemic nature of the lesion in dyshormonal pathology is due to the common links of pathogenesis. The leading factor in the pathogenesis of hormone-dependent pathology is absolute or relative hyperestrogenism. Menstrual disorders (MD) is one of the most overlooked problems in modern gynecology. Over the past decade, an increase in the frequency of MD in women of reproductive age has been noted in the world by almost 11 times. In the structure of gynecological morbidity, according to most authors, MD s account for about 60% of all dyshormonal disorders, which often lead to an underestimation of future not only reproductive, but also general somatic problems: from miscarriage and infertility to the formation of both benign and malignant tumors in the female organism. Keywords: hormone-dependent pathology, menstrual disorders, estrogens, progesterone, treatment, indole-3-carbinol, rod extract, Agidol.

scholarly journals ENDOSCOPIC HEMOSTASIS IN ULCERATIVE GASTRODUODENAL BLEEDING USING HIGH-FREQUENCY BIOLOGICAL WELDING ELECTROLIGATION

2021 ◽  
Vol 74 (9) ◽  
pp. 2159-2162
Author(s):  
Yaroslav P. Feleshtynskyi ◽  
Sergiy O. Oparin ◽  
Bogdan V. Sorokin ◽  
Margaryta G. Boiarskaia ◽  
Dmytro V. Lutsenko
Keyword(s):  
Treatment Group ◽  
High Frequency ◽  
Argon Plasma Coagulation ◽  
Argon Plasma ◽  
Early Recurrence ◽  
Endoscopic Hemostasis ◽  
Surgical Interventions ◽  
Plasma Coagulation ◽  
Primary Hemostasis ◽  
Experimental Group

The aim: To increase the efficiency of endoscopic hemostasis in ulcerative gastroduodenal bleeding using high-frequency biological welding electroligation. Materials and methods: The evaluation of endoscopic hemostasis in 160 patients aged 40 to 85 years with ulcerative gastroduodenal bleeding for the period from 2017 to 2020 was carried out. The patients were divided into two groups: the first (treatment) group involved 80 patients who underwent high-frequency biological welding electroligation, the second (experimental) group consisted of 80 patients who underwent monopolar thermal argon plasma coagulation. Results: In the first (treatment) group of patients with ulcerative gastroduodenal bleeding, who underwent endoscopic hemostasis using high-frequency biological welding electroligation, primary hemostasis was achieved in 77 cases (96.25%). In the first group, an early recurrence of bleeding was registered in 3 patients (3.75%). In the second (experimental) group of patients with ulcerative gastroduodenal bleeding, who underwent endoscopic hemostasis using monopolar thermal argon plasma coagulation, primary hemostasis was achieved in 66 cases (82.5%). In the second group, a recurrence of bleeding was observed in 14 patients (17.5%). Conclusions: The use of high-frequency biological welding electroligation for endoscopic hemostasis in ulcerative gastroduodenal bleeding provides a more reliable permanent hemostasis compared to the use of monopolar thermal argon plasma coagulation (77 (96.5%) and 66 (82.5%) cases, respectively). The frequency of bleeding recurrence is reduced to 3.5% and 17.5%, respectively, and the number of surgical interventions for acute bleeding in case of recurrence is decreased to 3 (3.5%) and 7 (8.75%), respectively.

THE 30 YEARS' CLINICAL EXPERIENCE IN DIAGNOSIS AND TREATMENT OF ENDOMETRIAL OVARIAN CYSTS IN PATIENTS OF REPRODUCTIVE AGE

2020 ◽  
pp. 21-24
Author(s):  
L. I. Hyrman ◽  
M. M. Kozub ◽  
M. P. Sokol
Keyword(s):  
Assisted Reproductive Technologies ◽  
Ovarian Tissue ◽  
Argon Plasma Coagulation ◽  
Argon Plasma ◽  
Reproductive Technologies ◽  
Reproductive Age ◽  
Ovarian Cysts ◽  
Plasma Coagulation ◽  
Post Surgery ◽  
Bipolar Energy

Endometriosis occurs in 50 % of women with infertility. Ovarian endometriosis affects 55 % of women with this disease. Surgical treatment of endometrium is indicated if its size is over 3 cm. After removal of the endometriomas there are used diathermic, bipolar energy, radio wave energy, argon plasma coagulation for hemostasis of ovarian tissue. The use of argon plasma coagulation in ovarian hemostasis causes not only hemostatic but also protective effect, which is mediated by the induction of HSP27, SOD2, VEGF and iNOS, which renders an organ−preserving effect when applied to ovarian tissues. Repeated surgery for ovarian endometrium should be performed taking into account the risk of reduced levels of antimullerian hormone, which may adversely affect the further implementation of reproductive function, including the use of assisted reproductive technologies. The authors comparatively have evaluated the treatment of 900 patients of reproductive age with endometrioid cysts of the ovaries and other concomitant gynecological pathology, which were three clinical groups. The patients received radiowave energy, argonoplasmic coagulation, intraoperative use of various anti−adhesive drugs and combinations of drugs in the postoperative period. It was found that the use of argon plasma coagulation for hemostasis of ovarian tissues after removal of endometrioid cysts, polyethylene oxide gel with carboxymethylcellulose intraoperatively and gonadotropin−releasing hormone agonists, dienogest 2 mg per day for three months contributed to the pregnancy onset in post−srugery period in 56.7 % of patients. It has been noted that in women the presence of adhesions in combination with corpus luteum cysts, endometrial polyps, uterine leiomyoma reduces the onset of pregnancy by 8.0, 12, and 24 times, respectively. Key words: endometrial ovarian cysts, diagnosis, treatment, rehabilitation in the post−surgery period.

Endoscopic mucosal resection for recurrent gastric antral vascular ectasia

VASA ◽  
2008 ◽  
Vol 37 (3) ◽  
pp. 289-292 ◽  
Author(s):  
Katsinelos ◽  
Chatzimavroudis ◽  
Katsinelos ◽  
Panagiotopoulou ◽  
Kotakidou ◽  
...  
Keyword(s):  
Endoscopic Mucosal Resection ◽  
Argon Plasma Coagulation ◽  
Argon Plasma ◽  
Deficiency Anemia ◽  
Gastric Antral Vascular Ectasia ◽  
Therapeutic Approaches ◽  
Plasma Coagulation ◽  
Vascular Ectasia ◽  
Mucosal Resection ◽  
First Case

Gastric antral vascular ectasia (GAVE) is an overt or occult source of gastrointestinal bleeding. Despite several therapeutic approaches have been successfully tested for preventing chronic bleeding, some patients present recurrence of GAVE lesions. To the best of our knowledge, we report the first case, of a 86-year-old woman who presented severe iron-deficiency anemia due to GAVE and showed recurrence of GAVE lesion despite the intensive argon plasma coagulation treatment. We performed endoscopic mucosal resection of bleeding GAVE with resolution of anemia.

Argon-Plasma-Coagulation (APC) zur lokalablativen Therapie des Cholangiokarzinoms

2015 ◽  
Vol 28 (01) ◽  
Author(s):  
A Genthner ◽  
A Eickhoff ◽  
J Albert ◽  
MD Enderle ◽  
W Linzenbold
Keyword(s):  
Argon Plasma Coagulation ◽  
Argon Plasma ◽  
Plasma Coagulation
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