Correlation of Serum IL-6 Levels with Muscle Mass, Muscle Strength, and Physical Performance in Elderly Gymnastics Community in Mohammad Hoesin General Hospital Palembang

Introduction. Old age is related to geriatric syndrome where there are several health problems that often occur related to a decrease in body function and an increase in the inflammatory process. Decrease in muscle mass, muscle strength and physical performance will cause a condition of sarcopenia and frailty syndrome in the elderly. The importance of prevention so that sarcopenia does not occur in the elderly by evaluating the factors that can cause it, one of which is controlling interleukin 6 (IL-6) as proinflammatory. The purpose of this study was to determine the correlation between serum IL-6 levels with muscle mass, muscle strength and physical performance in the elderly gymnastics-community in Mohammad Hoesin General Hospital, Palembang. Methods. This research is an observational analytic study with a cross-sectional approach which was conducted at the Integrated Geriatric Clinic Internal Medicine RSMH Palembang from November 2019 to November 2020. A sample of 31 people aged > 60 years was examined for muscle mass, muscle strength, physical performance and IL-levels. 6 serum. All data processing and analysis in this study used the SPSS version 25 for Windows program. Results. of the 31 subjects, 27 were female (87.1%) and 4 male (12.9%). The mean value of muscle mass is37.9 kg/m2, muscle strength 23 kg, and physical performance 6.1 m/sec.There were 28 (90.3%) samples with elevated serum IL-6 levels, while 3 (9.7%) samples had normal levels. There was a significant negative correlation (p = 0.000) with a strong correlation strength (r = -0.722) between serum IL-6 levels and muscle mass and a significant negative correlation (p = 0.050) with a weak correlation strength (r = -0.354) between IL levels -6 serums with physical performance. Conclusions. There was a significant negative correlation between serum IL-6 levels and muscle mass and physical performance. So, it is very important to prevent an increase in serum IL-6 levels so that the elderly do not fall into a state of sarcopenia.

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The Role of Serum Omega 3 Levels on Muscle Mass, Muscle Strength, and Physical Performance in the Elderly Community

BioScientia Medicina ◽

10.32539/bsm.v5i3.220 ◽

2021 ◽

Vol 5 (3) ◽

pp. 329-339

Author(s):

Welly Salutondok ◽

Nur Riviati ◽

Yulianto kusnadi ◽

Erial Bahar ◽

Nova Kuniati ◽

...

Keyword(s):

Muscle Strength ◽

Muscle Mass ◽

Physical Performance ◽

Significant Relationship ◽

The Elderly ◽

Mean Value ◽

Geriatric Syndrome ◽

Omega 3 ◽

Cross Sectional ◽

Geriatric Clinic

A B S T R A C TIntroduction. Old age is related to geriatric syndrome where there are several healthproblems that often occur related to a decrease in body function and an increase inthe inflammatory process. Decrease in muscle mass, muscle strength and physicalperformance will lead to a condition of sarcopenia and frailty syndrome in the elderly.The importance of prevention so that sarcopenia does not occur in the elderly byevaluating the factors that can cause it, one of which is controlling nutritional factors(macro and micro nutrients), such as in research, namely omega-3 macronutrients.The purpose of this study was to determine the correlation between serum omega-3levels with muscle mass, muscle strength, and physical performance in the elderlycommunity at Moehammad Hoesin Hospital Palembang. Methods. This research isan observational analytic study with a cross-sectional approach which wasconducted at the Integrated Geriatric Clinic Internal Medicine RSMH Palembangfrom November 2019 to November 2020. A sample of 21 people aged> 60 years wasexamined for muscle mass, muscle strength, physical performance and omega-levels. 3 serums. All data processing and analysis in this study used SPSS version25 for Windows. Results. Of the 21 subjects, it was found that women were 19people (90.5%) and 2 men (9.5%). The mean value of muscle mass was 37.65 ± 5.7,hand grip strength was 24.04 ± 5 kg, and walking speed was 6.72 ± 1.8 seconds per6 meters. There were 11 subjects with low serum omega-3 levels of 485.25 ± 110.19mg. There was a significant relationship between serum omega-3 levels and musclemass (p = 0.041) with moderate correlation strength (r = 0.448). Conclusion: Musclemass has a significant relationship with serum omega-3 levels in the elderly withmoderate strength. Meanwhile, muscle strength and physical performance did nothave a significant relationship.

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The Role of Serum Omega 3 Levels on Muscle Mass, Muscle Strength, and Physical Performance in the Elderly Community

BioScientia Medicina ◽

10.32539/bsm.v5i2.220 ◽

2021 ◽

Vol 5 (2) ◽

pp. 286-296

Author(s):

Welly Salutondok ◽

Nur Riviati ◽

Yulianto kusnadi ◽

Erial Bahar ◽

Nova Kuniati ◽

...

Keyword(s):

Muscle Strength ◽

Muscle Mass ◽

Physical Performance ◽

Significant Relationship ◽

The Elderly ◽

Mean Value ◽

Geriatric Syndrome ◽

Omega 3 ◽

Cross Sectional ◽

Geriatric Clinic

A B S T R A C TIntroduction. Old age is related to geriatric syndrome where there are several healthproblems that often occur related to a decrease in body function and an increase inthe inflammatory process. Decrease in muscle mass, muscle strength and physicalperformance will lead to a condition of sarcopenia and frailty syndrome in the elderly.The importance of prevention so that sarcopenia does not occur in the elderly byevaluating the factors that can cause it, one of which is controlling nutritional factors(macro and micro nutrients), such as in research, namely omega-3 macronutrients.The purpose of this study was to determine the correlation between serum omega-3levels with muscle mass, muscle strength, and physical performance in the elderlycommunity at Moehammad Hoesin Hospital Palembang. Methods. This research isan observational analytic study with a cross-sectional approach which wasconducted at the Integrated Geriatric Clinic Internal Medicine RSMH Palembangfrom November 2019 to November 2020. A sample of 21 people aged> 60 years wasexamined for muscle mass, muscle strength, physical performance and omega-levels. 3 serums. All data processing and analysis in this study used SPSS version25 for Windows. Results. Of the 21 subjects, it was found that women were 19people (90.5%) and 2 men (9.5%). The mean value of muscle mass was 37.65 ± 5.7,hand grip strength was 24.04 ± 5 kg, and walking speed was 6.72 ± 1.8 seconds per6 meters. There were 11 subjects with low serum omega-3 levels of 485.25 ± 110.19mg. There was a significant relationship between serum omega-3 levels and musclemass (p = 0.041) with moderate correlation strength (r = 0.448). Conclusion: Musclemass has a significant relationship with serum omega-3 levels in the elderly withmoderate strength. Meanwhile, muscle strength and physical performance did nothave a significant relationship.

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Association between Muscle Mass and Muscle Strength with Physical Performance in Elderly in Surabaya

Surabaya Physical Medicine and Rehabilitation Journal ◽

10.20473/spmrj.v2i1.2020.24-34 ◽

2020 ◽

Vol 2 (1) ◽

pp. 24

Author(s):

Titin Kristiana ◽

Novira Widajanti ◽

Rwahita Satyawati

Keyword(s):

Muscle Strength ◽

Muscle Mass ◽

Physical Performance ◽

Handgrip Strength ◽

Positive Association ◽

The Elderly ◽

Bivariate Analysis ◽

Weak Correlation ◽

Elderly Age ◽

Cross Sectional

ABSTRACTBackground: Sarcopenia is a decrease in muscle mass and strength that mostly happens in the elderly. Sarcopenia is a problem that is often found in the elderly who are at risk of disability, hospitalization and death. This data on muscle mass and strength with physical performance is expected to support the theory of sarcopenia and as a reference in promoting and preventing sarcopenia in elderly.Aims: To analyze the association between muscle mass and strength (handgrip strength) with physical performance assessed using Short Physical Performance Battery (SPPB) in an elderly community.Methods: This study was a cross-sectional observational analytic study involving 203 sample of elderly (age >60 years old). The subjects were categorized as the strong and weak muscle mass and muscle strength, also the high, moderate and low physical performance. We used Bioimpedance Analysis (BIA) and hand dynamometer to measure muscle mass and muscle strength (handgrip strength). SPPB was used to assess physical performance.The association between muscle mass and strength with physical performance was displayed in bivariate analysis with chi square.Result: Of all 203 subjects, 57 were males and 146 were females. Chi square test showed association between muscle strength (handgrip strength) with physical performance (SPPB) (p=0.001), with a weak correlation (r=0.26) and no association between muscle mass and physical performance (SPPB) (p=0.517).Conclusion: There is a positive association between muscle strength with physical performance, with a weak correlation and no association between muscle mass and physical performance in the elderly community in Surabaya.

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Potential of Omega-3 Supplementation on Muscle Mass, Muscle Strength, and Physical Performance in Elderly Community

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2021.5601 ◽

2021 ◽

Vol 9 (B) ◽

pp. 55-59

Author(s):

Nur Riviati ◽

Taufik Indrajaya ◽

Erial Bahar ◽

Dobi Saputra Burni

Keyword(s):

Muscle Strength ◽

Muscle Mass ◽

Physical Performance ◽

Functional Ability ◽

Functional Performance ◽

Handgrip Strength ◽

Bioelectrical Impedance ◽

Impedance Analysis ◽

The Elderly ◽

Omega 3

BACKGROUND: Geriatric problem characterized by reduced functional ability and impaired adaptation function caused by the decline in various body systems, as well as increased vulnerability to various kinds of stressors, which reduce a person’s functional performance. AIM: This study was aimed to explore the effect of omega-3 supplementation on muscle mass, muscle strength, and physical performance in the elderly community in Palembang, Indonesia. METHODS: This study is an open clinical trial, to assess the potential of omega-3 supplementation on muscle mass, handgrip strength, and physical activity of elderly community. Omega-3 is given as much as 1.2 g once a day for 12 weeks orally. Muscle strength was assessed using Bioelectrical Impedance Analysis. Meanwhile, the muscle strength was assessed with a muscle dynamometer. RESULTS: Omega-3 supplementation has only shown potent efficacy in improving muscle strength in geriatrics patients (before omega-3 supplementation 25.1 + 5.11; after omega-3 supplementation 26.2 + 5.16; p < 0.05). Omega 3 supplementation did not show significant improvement in muscle mass and gait ability in elderly patients. CONCLUSIONS: Omega-3 supplementation improves handgrip strength but does not increase muscle mass and physical performance for geriatrics.

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Elastic Band Training Effect to Parameters of Sarcopenia in Elderly Community-Dwelling

Global Medical & Health Communication (GMHC) ◽

10.29313/gmhc.v7i2.4468 ◽

2019 ◽

Vol 7 (2) ◽

Author(s):

Vitriana Biben ◽

Irma Ruslina Defi ◽

Derry Suselo

Keyword(s):

Muscle Strength ◽

Muscle Mass ◽

Physical Performance ◽

Bioelectrical Impedance ◽

Impedance Analysis ◽

The Elderly ◽

Community Dwelling ◽

Walking Distance ◽

Elastic Band ◽

Strengthening Exercise

Physiologically aging causes the decreased of muscle mass, strength, and or limited activity known as sarcopenia in the elderly. The decrease in muscle capacity occurs in all elderly, active, or sedentary. Exercise for the elderly is considered not enough to prevent the decrease of function that will occur. Therefore, it is necessary to add strength training to the elderly, such as elastic band exercise. The effect of strength training in 12 weeks with elastic band strengthening exercise on muscle mass, muscle strength, and physical performance as sarcopenia parameters measured in this study. The interventional study design was conducted in elderly community-dwelling in Bandung city, West Java, from May to July 2016. Thirty elderly (60–81 years old) muscle mass measured using bioelectrical impedance analysis (BIA), handgrip strength using hand dynamometer and walking distance as the parameter of physical performance, using 6-minute walking test. Significant differences found in hand muscle strength (p=0.007), walking distance (p=0.000) after elastic band strengthening exercise, but there were no significant changes in muscle mass (p=0.236) even though the muscle mass increased after 12 weeks of strengthening exercise. In conclusion, additional elastic band strength exercise for regular elderly exercise can increase muscle strength and physical performance. PENGARUH LATIHAN DENGAN PITA ELASTIK TERHADAP PARAMETER SARKOPENIA PADA USILA DI KOMUNITASPenuaan secara fisiologis menyebabkan penurunan massa, kekuatan otot dan/atau keterbatasan aktivitas pada usia lanjut (usila). Penurunan kemampuan otot ini terjadi pada semua usila, baik yang aktif maupun nonaktif sehingga senam usila yang ada dianggap tidak mencukupi untuk mencegah penurunan fungsi yang akan terjadi. Oleh karena itu, diperlukan penambahan latihan kekuatan pada usila seperti latihan kekuatan menggunakan pita elastik. Penelitian ini bertujuan mengetahui pengaruh latihan kekuatan dengan pita elastik selama 12 minggu terhadap massa otot, kekuatan otot, dan performa fisik yang merupakan parameter sarkopenia pada usila. Desain penelitian intervensi dilakukan pada usila di komunitas Kota Bandung, Jawa Barat periode bulan Mei sampai Juli 2016. Sebanyak 30 partisipan (usia 60–81 tahun) diukur massa otot menggunakan bioelectrical impedance analysis (BIA) dan kekuatan otot menggunakan dinamometer tangan, serta uji jalan 6 menit untuk mengukur performa fisik. Perbedaan bermakna ditemukan pada kekuatan otot tangan (p=0,007) dan jarak tempuh jalan (p=0,000) setelah dilakukan latihan kekuatan dengan pita elastik, tetapi tidak didapatkan perbedaan bermakna pada massa otot tangan dan kaki (p=0,236) walaupun terjadi peningkatan massa otot setelah dilakukan latihan selama 12 minggu. Simpulan, penambahan latihan kekuatan dengan pita elastik pada program senam usila meningkatkan secara bermakna kekuatan otot dan performa fisik usila.

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Association between Muscle Mass and Muscle Strength with Physical Performance in Elderly in Surabaya

Surabaya Physical Medicine and Rehabilitation Journal ◽

10.20473/spmrj.v2i1.16313 ◽

2020 ◽

Vol 2 (1) ◽

pp. 24

Author(s):

Titin Kristiana ◽

Novira Widajanti ◽

Rwahita Satyawati

Keyword(s):

Muscle Strength ◽

Muscle Mass ◽

Physical Performance ◽

Handgrip Strength ◽

Positive Association ◽

The Elderly ◽

Bivariate Analysis ◽

Weak Correlation ◽

Elderly Age ◽

Cross Sectional

ABSTRACTBackground: Sarcopenia is a decrease in muscle mass and strength that mostly happens in the elderly. Sarcopenia is a problem that is often found in the elderly who are at risk of disability, hospitalization and death. This data on muscle mass and strength with physical performance is expected to support the theory of sarcopenia and as a reference in promoting and preventing sarcopenia in elderly.Aims: To analyze the association between muscle mass and strength (handgrip strength) with physical performance assessed using Short Physical Performance Battery (SPPB) in an elderly community.Methods: This study was a cross-sectional observational analytic study involving 203 sample of elderly (age >60 years old). The subjects were categorized as the strong and weak muscle mass and muscle strength, also the high, moderate and low physical performance. We used Bioimpedance Analysis (BIA) and hand dynamometer to measure muscle mass and muscle strength (handgrip strength). SPPB was used to assess physical performance.The association between muscle mass and strength with physical performance was displayed in bivariate analysis with chi square.Result: Of all 203 subjects, 57 were males and 146 were females. Chi square test showed association between muscle strength (handgrip strength) with physical performance (SPPB) (p=0.001), with a weak correlation (r=0.26) and no association between muscle mass and physical performance (SPPB) (p=0.517).Conclusion: There is a positive association between muscle strength with physical performance, with a weak correlation and no association between muscle mass and physical performance in the elderly community in Surabaya.

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Sarcopenia and homocysteine: is there a possible association in the elderly? A narrative review

Nutrition Research Reviews ◽

10.1017/s095442242100010x ◽

2021 ◽

pp. 1-36

Author(s):

Rachele De Giuseppe ◽

Chiara Elena Tomasinelli ◽

Alessandra Vincenti ◽

Ilaria Di Napoli ◽

Massimo Negro ◽

...

Keyword(s):

Muscle Strength ◽

Muscle Mass ◽

Physical Performance ◽

Working Group ◽

The Elderly ◽

Adverse Outcomes ◽

Narrative Review ◽

Increased Risk ◽

European Working ◽

Muscle Homeostasis

Abstract Background Sarcopenia (SA) is a progressive skeletal muscle disorder, associated with increased risk of adverse outcomes, including falls, fractures, physical disability and mortality. Several risks factors may contribute to the development of SA in the elderly; among them, nutrition plays a key role in muscle health. The elderly are at risk of inadequate intake in terms of micronutrients affecting muscle-homeostasis, such as B vitamins, related to homocysteine (Hcy) metabolism. Objectives and Methods This narrative review analysed the association between increased Hcy levels and SA, according to the criteria of the International Working Group on Sarcopenia, the European Working Group on Sarcopenia in Older People and the Asian Working Group for Sarcopenia. The authors focused not only on SA per se but also on exploring the association between increased Hcy levels and components of SA, including muscle mass, muscle strength and physical performance. Results Results are inconsistent, except for muscle mass, showing no significant associations with Hcy levels. Conclusions Few and conflicting data emerged in this review on the association between SA and increased Hcy levels due to numerous differences between studies that change the significance of the association of Hcy and SA, as well as with the muscle strength, muscle mass and physical performance. Furthermore, because the ageing process is not uniform in the population due to differences in genetics, lifestyle and general health, chronological age fails to address the observed heterogeneity among the "elderly" of the studies reported in this revision. Therefore, further studies are still needed.

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Correlation of Vitamin D Serum Levels with Muscle Mass, Muscle Strength, and Physical Performance in the Elderly Community in Mohammad Hoesin General Hospital Palembang

BioScientia Medicina ◽

10.32539/bsm.v5i2.225 ◽

2021 ◽

Vol 5 (2) ◽

pp. 332-334

Author(s):

Noveldy Calzoum Bachry ◽

Nur Riviati ◽

Yulianto kusnadi ◽

Erial Bahar

Keyword(s):

Vitamin D ◽

Muscle Strength ◽

Muscle Mass ◽

Physical Performance ◽

Serum Vitamin ◽

The Elderly ◽

The Body ◽

Serum Vitamin D ◽

Hand Grip ◽

Vitamin D Levels

A B S T R A C TIntroductionOlder people tend to have decreased activity and intake of macronutrients andmicronutrients that are not in accordance with the body's needs. Research in 2017on elderly men and women at the Center for Family Compensation (PUSAKA) inCentral Jakarta showed that 80.2% of elderly people have vitamin D deficiency. Lowserum levels of vitamin D in the body are the initial risk of decreased muscle massand physical performance in old age. where there is a significant correlation betweenlow serum vitamin D levels in the body with sarcopenia and mortality. The purposeof this study was to determine the correlation of vitamin D levels with muscle mass,muscle strength and physical performance in the elderly community at RSMHPalembang. Methods This research is a study analytic observation with a cross-sectional approach that was carried out at the Integrated Geriatric Clinic InternalMedicine RSMH Palembang from November 2019 to November 2020. A sample of 34people aged> 60 years were examined for muscle mass, muscle strength, physicalperformance and serum vitamin D levels. All processing and analysis The data inthis study used SPSS version 25 for Windows. Results From 34 subjects, it wasfound that there were 29 women (85.3%) and 5 men (14.7%). The mean value ofmuscle mass is38.76 ± 4.1 kg / m2, long runs within 6 meters 6.12± 0.9 m / sec,and hand grip strength 24.9 ± 5.2 kg. It was found that 18 (62.1%) female sampleshad vitamin D deficiency while 11 (37.9%) samples had vitamin D insufficiency.There was a significant correlation between muscle mass and hand grip strengthwith vitamin D with weak correlation strength and length of walking with vitamin Dwith moderate correlation strength.Conclusion There is a significant correlationbetween muscle mass and grip strength and walking time of 6 meters with vitaminD.

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