scholarly journals Elastic Band Training Effect to Parameters of Sarcopenia in Elderly Community-Dwelling

2019 ◽  
Vol 7 (2) ◽  
Author(s):  
Vitriana Biben ◽  
Irma Ruslina Defi ◽  
Derry Suselo
Keyword(s):  
Muscle Strength ◽  
Muscle Mass ◽  
Physical Performance ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
The Elderly ◽  
Community Dwelling ◽  
Walking Distance ◽  
Elastic Band ◽  
Strengthening Exercise

Physiologically aging causes the decreased of muscle mass, strength, and or limited activity known as sarcopenia in the elderly. The decrease in muscle capacity occurs in all elderly, active, or sedentary. Exercise for the elderly is considered not enough to prevent the decrease of function that will occur. Therefore, it is necessary to add strength training to the elderly, such as elastic band exercise. The effect of strength training in 12 weeks with elastic band strengthening exercise on muscle mass, muscle strength, and physical performance as sarcopenia parameters measured in this study. The interventional study design was conducted in elderly community-dwelling in Bandung city, West Java, from May to July 2016. Thirty elderly (60–81 years old) muscle mass measured using bioelectrical impedance analysis (BIA), handgrip strength using hand dynamometer and walking distance as the parameter of physical performance, using 6-minute walking test. Significant differences found in hand muscle strength (p=0.007), walking distance (p=0.000) after elastic band strengthening exercise, but there were no significant changes in muscle mass (p=0.236) even though the muscle mass increased after 12 weeks of strengthening exercise. In conclusion, additional elastic band strength exercise for regular elderly exercise can increase muscle strength and physical performance. PENGARUH LATIHAN DENGAN PITA ELASTIK TERHADAP PARAMETER SARKOPENIA PADA USILA DI KOMUNITASPenuaan secara fisiologis menyebabkan penurunan massa, kekuatan otot dan/atau keterbatasan aktivitas pada usia lanjut (usila). Penurunan kemampuan otot ini terjadi pada semua usila, baik yang aktif maupun nonaktif sehingga senam usila yang ada dianggap tidak mencukupi untuk mencegah penurunan fungsi yang akan terjadi. Oleh karena itu, diperlukan penambahan latihan kekuatan pada usila seperti latihan kekuatan menggunakan pita elastik. Penelitian ini bertujuan mengetahui pengaruh latihan kekuatan dengan pita elastik selama 12 minggu terhadap massa otot, kekuatan otot, dan performa fisik yang merupakan parameter sarkopenia pada usila. Desain penelitian intervensi dilakukan pada usila di komunitas Kota Bandung, Jawa Barat periode bulan Mei sampai Juli 2016. Sebanyak 30 partisipan (usia 60–81 tahun) diukur massa otot menggunakan bioelectrical impedance analysis (BIA) dan kekuatan otot menggunakan dinamometer tangan, serta uji jalan 6 menit untuk mengukur performa fisik. Perbedaan bermakna ditemukan pada kekuatan otot tangan (p=0,007) dan jarak tempuh jalan (p=0,000) setelah dilakukan latihan kekuatan dengan pita elastik, tetapi tidak didapatkan perbedaan bermakna pada massa otot tangan dan kaki (p=0,236) walaupun terjadi peningkatan massa otot setelah dilakukan latihan selama 12 minggu. Simpulan, penambahan latihan kekuatan dengan pita elastik pada program senam usila meningkatkan secara bermakna kekuatan otot dan performa fisik usila.

scholarly journals Potential of Omega-3 Supplementation on Muscle Mass, Muscle Strength, and Physical Performance in Elderly Community

2021 ◽  
Vol 9 (B) ◽  
pp. 55-59
Author(s):  
Nur Riviati ◽  
Taufik Indrajaya ◽  
Erial Bahar ◽  
Dobi Saputra Burni
Keyword(s):  
Muscle Strength ◽  
Muscle Mass ◽  
Physical Performance ◽  
Functional Ability ◽  
Functional Performance ◽  
Handgrip Strength ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
The Elderly ◽  
Omega 3

BACKGROUND: Geriatric problem characterized by reduced functional ability and impaired adaptation function caused by the decline in various body systems, as well as increased vulnerability to various kinds of stressors, which reduce a person’s functional performance. AIM: This study was aimed to explore the effect of omega-3 supplementation on muscle mass, muscle strength, and physical performance in the elderly community in Palembang, Indonesia. METHODS: This study is an open clinical trial, to assess the potential of omega-3 supplementation on muscle mass, handgrip strength, and physical activity of elderly community. Omega-3 is given as much as 1.2 g once a day for 12 weeks orally. Muscle strength was assessed using Bioelectrical Impedance Analysis. Meanwhile, the muscle strength was assessed with a muscle dynamometer. RESULTS: Omega-3 supplementation has only shown potent efficacy in improving muscle strength in geriatrics patients (before omega-3 supplementation 25.1 + 5.11; after omega-3 supplementation 26.2 + 5.16; p < 0.05). Omega 3 supplementation did not show significant improvement in muscle mass and gait ability in elderly patients. CONCLUSIONS: Omega-3 supplementation improves handgrip strength but does not increase muscle mass and physical performance for geriatrics.

scholarly journals A Prospective Observational Study Evaluating Sarcopenia By Using the Bioelectrical Impedance Analysis in Elderly Patients with Hematologic Malignancies

Blood ◽  
2018 ◽  
Vol 132 (Supplement 1) ◽  
pp. 4851-4851 ◽  
Author(s):  
Takahiro Kamiya ◽  
Kota Mizuno ◽  
Shinji Ogura ◽  
Chisako Ito ◽  
Yuriko Fujita ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Strength ◽  
Elderly Patients ◽  
Muscle Mass ◽  
Physical Performance ◽  
Bioelectrical Impedance Analysis ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Hematologic Malignancies ◽  
Skeletal Muscle Index

Abstract [Introduction] Sarcopenia is characterized by age-related decline of skeletal muscle plus low muscle strength and/or physical performance. Previous studies have confirmed the association of sarcopenia and adverse health outcomes, such as falls, disability, hospital admission, long term care placement, poorer quality of life, and mortality, which denotes the importance of sarcopenia in the health care for older people. Population-based studies reported that the prevalence of sarcopenia in Japanese healthy adults aged≥60 years was 8.5% among men and 8.0% among women. Sarcopenia was recently identified as a poor prognostic factor in patients with solid tumors. In cancer patients, sarcopenia is associated with treatment failure, chemotherapy toxicity, and a shorter time to tumor progression related to survival. In contrast to solid tumors, the clinical relevance of sarcopenia in hematologic malignancies is still unknown. The present study investigated the prevalence of sarcopenia based on the criteria of the Asian Working Group for Sarcopenia (AWGS) in elderly patients with hematologic malignancies. [Patients and Methods] We prospectively analyzed 56 elderly patients aged≥60 years with hematologic malignancies diagnosed at our institution between 2015 and 2018. Appendicular skeletal muscle mass (ASM) was measured at diagnosis by using multifrequency bioelectrical impedance analysis (BIA) (InBody 720). BIA is suitable for body composition monitoring in elderly patients as a fast, noninvasive, and convenient method. Skeletal muscle index (SMI) was defined as the ratio of ASM divided by height in square centimeters. We also evaluated physical function by using short physical performance buttery (SPPB). Sarcopenia was defined according to the AWGS algorithm, in which the patient has low muscle mass, and low muscle strength or low physical performance. Low muscle mass was defined as a skeletal muscle index (SMI: ASM/height2) of <7.0kg/m2 in men and <5.7kg/m2 in women. Pre-sarcopenia was defined as having only low muscle mass. Low muscle strength was defined as a handgrip strength of <26kg in men and <18kg in women; and low physical performance, as a gait speed of <0.8m/sec. The study protocol was approved by the Institutional Review Board of Yokohama Municipal Citizen's Hospital, and it was carried out in accordance with the Declaration of Helsinki. [Results] Median age at diagnosis was 77 years (60-93 years), with 34 males and 22 females. The diagnosis included non-Hodgkin lymphoma (NHL, n=36), multiple myeloma (MM, n=9), myelodysplastic syndrome (MDS, n=10), and acute myeloid leukemia (AML, n=1). The prevalence of low muscle mass (pre-sarcopenia) was 41% (14/34) in men and 77% (17/22) in women. The prevalence of low muscle strength was 35% (12/34) in men and 41% (9/22) in women. The prevalence of low physical performance status (Gait speed:<0.8m/sec) was 6% (2/34) in men and 9% (2/22) in women. The prevalence of sarcopenia based on a diagnosis of low muscle mass, low muscle strength, and low physical performance was 24% (8/34) in men and (8/22) 36% in women. The prevalence of low SPPB score (<10) was 9% (3/34) in men and 18% (4/22) in women. Among 36 NHL patients, the diagnosis included DLBCL (n=15), FL (n=10), MALT (n=3), SMZBCL (n=3), MCL (n=2), and others. The prevalence of sarcopenia was 25% (5/20) in men and 50% (8/16) in women. The mean age was 83 years in the sarcopenic group (n=13, 36%) and 73 years in the non-sarcopenic group (n=23, 64%) (p=0.0001). Sarcopenic patients displayed a similar level of serum albumin, LDH, sIL2-R, and BMI when compared with patients who were not sarcopenic. However, sarcopenic patients displayed significantly lower levels of serum dehydroepiandrosterone-sulfate (DHEA-S) and a higher CCI score than patients who were not sarcopenic. Sarcopenic patients failed to complete the treatment planned as compared with non-sarcopenic patients (p=0.001). [Conclusion] These results demonstrated that the prevalence of sarcopenia in elderly patients with hematologic malignancies is higher than that in the Japanese general elderly population. In particular, the prevalence of sarcopenia in female NHL patients is higher than that in male NHL patients. Several factors such as age, serum DHEA-S or comorbidities may affect the incidence of sarcopenia. Since our results are based on a small-sized analysis, further large prospective studies are warranted to verify this conclusion. Disclosures No relevant conflicts of interest to declare.

scholarly journals A simpler screening tool for sarcopenia in surgical patients

PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0257672
Author(s):  
Onuma Chaiwat ◽  
Mingkwan Wongyingsinn ◽  
Weerasak Muangpaisan ◽  
Chalobol Chalermsri ◽  
Arunotai Siriussawakul ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Muscle Mass ◽  
Physical Performance ◽  
Skeletal Muscle Mass ◽  
Screening Tool ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Surgical Patients ◽  
Simple Tool ◽  
Sensitivity Specificity

Background Sarcopenia is defined as decreased skeletal muscle mass and muscle functions (strength and physical performance). Muscle mass is measured by specific methods, such as bioelectrical impedance analysis and dual-energy X-ray absorptiometry. However, the devices used for these methods are costly and are usually not portable. A simple tool to screen for sarcopenia without measuring muscle mass might be practical, especially in developing countries. The aim of this study was to design a simple screening tool and to validate its performance in screening for sarcopenia in older adult cancer patients scheduled for elective surgery. Methods Cancer surgical patients aged >60 years were enrolled. Their nutritional statuses were evaluated using the Mini Nutrition Assessment-Short Form. Sarcopenia was assessed using Asian Working Group for Sarcopenia (AWGS) criteria. Appendicular skeletal muscle mass was measured by bioelectrical impedance analysis. Four screening formulas with differing combinations of factors (muscle strength, physical performance, and nutritional status) were assessed. The validities of the formulas, compared with the AWGS definition, are presented as sensitivity, specificity, accuracy, and area under a receiver operating characteristic curve. Results Of 251 enrolled surgical patients, 84 (34%) were diagnosed with sarcopenia. Malnutrition (odds ratio [OR]: 2.89, 95% CI: 1.40–5.93); underweight status (OR: 2.80, 95% CI: 1.06–7.43); and age increments of 5 years (OR: 1.78, 95% CI: 1.41–2.24) were independent predictors of preoperative sarcopenia. The combination of low muscle strength and/or abnormal physical performance, plus malnutrition/risk of malnutrition had the highest sensitivity, specificity, and accuracy (81.0%, 78.4%, and 79.3%, respectively). This screening formula estimated the probability of sarcopenia with a positive predictive value of 65.4% and a negative predictive value of 89.1%. Conclusion Sarcopenia screening can be performed using a simple tool. The combination of low muscle strength and/or abnormal physical performance, plus malnutrition/risk of malnutrition, has the highest screening performance.

Relationship between trunk muscle strength and trunk muscle mass and thickness using bioelectrical impedance analysis and ultrasound imaging

2021 ◽  
pp. 1-10
Author(s):  
Ryo Miyachi ◽  
Nana Koike ◽  
Suzu Kodama ◽  
Junya Miyazaki
Keyword(s):  
Muscle Strength ◽  
Muscle Mass ◽  
Ultrasound Imaging ◽  
Bioelectrical Impedance Analysis ◽  
Muscle Thickness ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Trunk Muscle ◽  
Trunk Muscles ◽  
Trunk Muscle Strength

BACKGROUND: Although trunk muscles are involved in many important functions, evaluating trunk muscle strength is not an easy task. If trunk muscle mass and thickness could be used as indicators of trunk muscle strength, the burden of measurement would be reduced, but the relationship between trunk muscle strength and trunk muscle mass and thickness has not been clarified. OBJECTIVE: The purpose of this study was to clarify the relationship between trunk muscle strength and trunk muscle mass by bioelectrical impedance analysis and trunk muscle thickness by ultrasound imaging in healthy adults. METHODS: One hundred and twenty-one healthy university students were included in this study. Trunk flexion/extension muscle strength and trunk muscle mass by bioelectrical impedance analysis, and trunk muscle thickness by ultrasound imaging were measured. RESULTS: Both trunk flexion strength and trunk extension strength were significantly correlated with trunk muscle mass and oblique and rectus abdominis muscle thickness. Multiple regression analysis showed that trunk extension muscle strength had an independent relationship with trunk muscle mass. CONCLUSIONS: This study demonstrated that trunk muscle mass or trunk muscle thickness can be used as an alternative means for evaluating trunk muscle strength, making the evaluation of trunk muscles less burdensome.

scholarly journals Nutritional Intervention to Prevent the Functional Decline in Community-Dwelling Older Adults: A Systematic Review

Nutrients ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2820
Author(s):  
Julie Mareschal ◽  
Laurence Genton ◽  
Tinh-Hai Collet ◽  
Christophe Graf
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Muscle Strength ◽  
Muscle Mass ◽  
Physical Performance ◽  
Nutritional Intervention ◽  
Community Dwelling ◽  
Health Concern ◽  
The Impact ◽  
Community Dwelling Older Adults

Aging is a global public health concern. From the age of 50, muscle mass, muscle strength and physical performance tend to decline. Sarcopenia and frailty are frequent in community-dwelling older adults and are associated with negative outcomes such as physical disability and mortality. Therefore, the identification of therapeutic strategies to prevent and fight sarcopenia and frailty is of great interest. This systematic review aims to summarize the impact of nutritional interventions alone or combined with other treatment(s) in older community-dwelling adults on (1) the three indicators of sarcopenia, i.e., muscle mass, muscle strength and physical performance; and (2) the hospitalization and readmission rates. The literature search was performed on Medline and included studies published between January 2010 and June 2020. We included randomized controlled trials of nutritional intervention alone or combined with other treatment(s) in community-living subjects aged 65 or older. In total, 28 articles were retained in the final analysis. This systematic review highlights the importance of a multimodal approach, including at least a combined nutritional and exercise intervention, to improve muscle mass, muscle strength and physical performance, in community-dwelling older adults but especially in frail and sarcopenic subjects. Regarding hospitalization and readmission rate, data were limited and inconclusive. Future studies should continue to investigate the effects of such interventions in this population.

Association between Muscle Mass and Muscle Strength with Physical Performance in Elderly in Surabaya

2020 ◽  
Vol 2 (1) ◽  
pp. 24
Author(s):  
Titin Kristiana ◽  
Novira Widajanti ◽  
Rwahita Satyawati
Keyword(s):  
Muscle Strength ◽  
Muscle Mass ◽  
Physical Performance ◽  
Handgrip Strength ◽  
Positive Association ◽  
The Elderly ◽  
Bivariate Analysis ◽  
Weak Correlation ◽  
Elderly Age ◽  
Cross Sectional

ABSTRACTBackground: Sarcopenia is a decrease in muscle mass and strength that mostly happens in the elderly. Sarcopenia is a problem that is often found in the elderly who are at risk of disability, hospitalization and death. This data on muscle mass and strength with physical performance is expected to support the theory of sarcopenia and as a reference in promoting and preventing sarcopenia in elderly.Aims: To analyze the association between muscle mass and strength (handgrip strength) with physical performance assessed using Short Physical Performance Battery (SPPB) in an elderly community.Methods: This study was a cross-sectional observational analytic study involving 203 sample of elderly (age >60 years old). The subjects were categorized as the strong and weak muscle mass and muscle strength, also the high, moderate and low physical performance. We used Bioimpedance Analysis (BIA) and hand dynamometer to measure muscle mass and muscle strength (handgrip strength). SPPB was used to assess physical performance.The association between muscle mass and strength with physical performance was displayed in bivariate analysis with chi square.Result: Of all 203 subjects, 57 were males and 146 were females. Chi square test showed association between muscle strength (handgrip strength) with physical performance (SPPB) (p=0.001), with a weak correlation (r=0.26) and no association between muscle mass and physical performance (SPPB) (p=0.517).Conclusion: There is a positive association between muscle strength with physical performance, with a weak correlation and no association between muscle mass and physical performance in the elderly community in Surabaya.

scholarly journals Prevalence of sarcopenia in community-dwelling older adults in Ireland: comparison of EWGSOP1 and EWGSOP2 definitions

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Caoileann Murphy ◽  
Aoibheann McMorrow ◽  
Ellen Flanagan ◽  
Helen Cummins ◽  
Sinead McCarthy ◽  
...  
Keyword(s):  
Older Adults ◽  
Muscle Strength ◽  
Muscle Mass ◽  
Physical Performance ◽  
Clinical Investigation ◽  
Community Dwelling ◽  
Muscle Disease ◽  
Cross Sectional ◽  
European Working ◽  
Community Dwelling Older Adults

AbstractSarcopenia is a muscle disease rooted in adverse muscle changes that accrue across a lifetime. It is an independent risk factor for numerous adverse health outcomes. In 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a definition for the identification of people with sarcopenia (EWGSOP1). In 2018, this definition was updated based on the newest evidence (EWGSOP2), with the focus now on low muscle strength rather than low muscle quantity as the key characteristic of sarcopenia. In addition, EWGSOP2 provides clear cut-off points for measurements of variables that identify sarcopenia. The aim of this study was to determine the prevalence of sarcopenia among community-dwelling older adults in Ireland for the first time and to assess agreement between the EWGSOP1 and EWGSOP2 definitions. In a cross-sectional analysis, 490 community-dwelling adults (age 78.4 ± 8.0 y, body mass index 27.6 ± 5.1 kg/m2) were assessed. Skeletal muscle mass was estimated using bioelectrical impedance analysis, muscle strength was measured via handgrip dynamometry and physical performance via the Short Physical Performance Battery. Sarcopenia was defined according to both the 2010 criteria (EWGSOP1) and the updated 2018 criteria (EWGSOP2). Using the EWGSOP1 criteria, the prevalence of sarcopenia was 7.1% (2.6% sarcopenia, 4.5% severe sarcopenia) and 3.6% were classified as pre-sarcopenic (low muscle mass without a decrement in strength or physical performance). Using the EWGSOP2 criteria, the prevalence of sarcopenia was 5.5% (1.6% sarcopenia, 3.9% severe sarcopenia) and 23.4 % were classified as having low strength but without a decrement in muscle mass. Five of the participants who were classified as sarcopenic (2 sarcopenia, 3 severe sarcopenia) by EWGSOP1 were classified as “normal” using the EWGSOP2 criteria. In conclusion, the prevalence of sarcopenia in community-dwelling older adults in Ireland is in line with the prevalence reported in other European countries using the EWGSOP1 criteria (3.3–11.4 %). To our knowledge this is the first study to compare the prevalence based on the EWGSOP1 and the EWGSOP2 criteria. We report a slightly lower prevalence using the EWGSOP2 definition compared to the EWGSOP1 definition. Importantly however, in contrast to EWGSOP1, the EWGSOP2 definition identified a substantial proportion of older adults with poor strength in the absence of overt sarcopenia (23.4%). These older adults represent a group who would benefit from further clinical investigation and intervention.

Comparison of single- or multifrequency bioelectrical impedance analysis and spectroscopy for assessment of appendicular skeletal muscle in the elderly

2013 ◽  
Vol 115 (6) ◽  
pp. 812-818 ◽  
Author(s):  
Yosuke Yamada ◽  
Yuya Watanabe ◽  
Masahiro Ikenaga ◽  
Keiichi Yokoyama ◽  
Tsukasa Yoshida ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Strength ◽  
Bioelectrical Impedance Analysis ◽  
Correlation Coefficients ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
The Elderly ◽  
Knee Extension ◽  
Appendicular Skeletal Muscle ◽  
Skeletal Muscle Strength

Bioelectrical impedance analysis (BIA) is used to assess skeletal muscle mass, although its application in the elderly has not been fully established. Several BIA modalities are available: single-frequency BIA (SFBIA), multifrequency BIA (MFBIA), and bioelectrical impedance spectroscopy (BIS). The aim of this study was to examine the difference between SFBIA, MFBIA, and BIS for assessment of appendicular skeletal muscle strength in the elderly. A total of 405 elderly (74.2 ± 5.0 yr) individuals were recruited. Grip strength and isometric knee extension strength were measured. Segmental SFBIA, MFBIA, and BIS were measured for the arms and upper legs. Bioelectrical impedance indexes were calculated by squared segment length divided by impedance ( L2/Z). Impedance at 5 and 50 kHz (Z5 and Z50) was used for SFBIA. Impedance of the intracellular component was calculated from MFBIA (Z250-5) and BIS (RICW). Correlation coefficients between knee extension strength and L2/Z5, L2/Z50, L2/RICW, and L2/Z250-5 of the upper legs were 0.661, 0.705, 0.790, and 0.808, respectively ( P < 0.001). Correlation coefficients were significantly greater for MFBIA and BIS than SFBIA. Receiver operating characteristic curves showed that L2/Z250-5 and L2/RICW had significantly larger areas under the curve for the diagnosis of muscle weakness compared with L2/Z5 and L2/Z50. Very similar results were observed for grip strength. Our findings suggest that MFBIA and BIS are better methods than SFBIA for assessing skeletal muscle strength in the elderly.

scholarly journals Testosterone but not estradiol level is positively related to muscle strength and physical performance independent of muscle mass: a cross-sectional study in 1489 older men

2011 ◽  
Vol 164 (5) ◽  
pp. 811-817 ◽  
Author(s):  
Tung Wai Auyeung ◽  
Jenny Shun Wah Lee ◽  
Timothy Kwok ◽  
Jason Leung ◽  
Claes Ohlsson ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Grip Strength ◽  
Muscle Mass ◽  
Physical Performance ◽  
Older Men ◽  
Community Dwelling ◽  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Cross Sectional ◽  
Skeletal Mass

ObjectiveTo examine the relationship between different measures of testosterone and estradiol (E2), muscle mass, muscle strength, and physical performance; and to test whether the association of sex hormone level with muscle strength and physical performance was independent of muscle mass.Design and methodsA cross-sectional survey on 1489 community-dwelling men older than 64 years of age. Serum levels of testosterone and E2were measured by mass spectrometry, and sex hormone-binding globulin (SHBG) levels were measured by immunoradioassay. Muscle mass was examined by dual-energy X-ray absorptiometry and physical performance was assessed by hand-grip strength, gait speed, step length and chair-stand test.ResultsAppendicular skeletal mass (ASM) was positively associated with total testosterone (TT;P<0.001), free testosterone (FT;P<0.001), and total E2(P<0.001) but not with free E2(P=0.102). After adjustment for age, serum SHBG and relative ASM, both TT and FT were significantly associated with grip strength, narrow-walk speed and the composite neuromuscular score. Higher total E2, but not free E2was associated with lower grip strength (P<0.05) after adjustment for age, FT, SHBG and relative ASM.ConclusionsTestosterone level was related to both muscle mass, strength and physical performance. Total E2level, though related to muscle mass positively, affected muscle strength adversely in older men.

Sign in / Sign up

Export Citation Format

Share Document