COMPARATIVE STUDY OF PERIPHERAL BONE MINERAL DENSITY IN GOVERNMENT AND   PRIVATE SCHOOL CHILDREN IN BIKANER DISTRICT RAJASTHAN

Summary -Peripheral bone density measurements are scarce and the factors, which predict bone mineral density at these sites, especially in children, are not clearly known. In this study, age, height, weight and BMI had a significant association on peripheral bone mineral density in healthy Indian school children. Introduction- Factors that lead to the attainment of peak bone mass at peripheral sites, during period of growth are not clearly known. Methods- Hundred children are randomly selected 7- to 17-year-old children from govt. and private schools were assessed clinically and a recording of their height and weight was undertaken. Bonemineral density measured by ultrasound bone densitometer. at the calcaneum (BMDca). Results -bone mineral density is assessed in correlation of following parameters:-When age wise BMD was analysed between both study groups, government school children had lower BMD values in both age groups (7-11 years, 12-17 years) and the difference between BMD in both age groups was statistically highly significant (p<0.01).Considering sex wise distribution of Bone mineral density it was clearly shown that BMD among private school children had higher values among both males and females, and the difference is statistically highly significant (p<0.01) among females. When Bone mineral density levels were compared according to BMI levels, the difference was observed to be not significantly associated with BMI levels (p>0.05) though government school children showed lower BMD levels as compared to private school children. Conclusion -age, nutrition, height and weight are significantly associated with BMD at peripheral sites. Keywords: Bone mineral density, Distal forearm, ultrasound bone densitometer, Socioeconomic status.

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The Difference of Bone Mineral Density of Lumbar Spine and Wrist in the Preterm and Full-term Infants: Using Dual Energy X-ray Absorptiometry

Journal of the Korean Radiological Society ◽

10.3348/jkrs.2000.43.3.371 ◽

2000 ◽

Vol 43 (3) ◽

pp. 371

Author(s):

Min Jung Cha ◽

Seung Cheol Kim ◽

Young Seok Lee ◽

Young Pyo Chang ◽

Jin Young Park

Keyword(s):

Bone Mineral Density ◽

Lumbar Spine ◽

Bone Mineral ◽

Dual Energy ◽

Full Term ◽

Mineral Density ◽

Term Infants ◽

X Ray ◽

The Difference

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Comparison of Central and Peripheral Bone Mineral Density Measurements in Postmenopausal Women

Journal of Chiropractic Medicine ◽

10.1016/j.jcm.2017.08.001 ◽

2017 ◽

Vol 16 (3) ◽

pp. 199-203 ◽

Cited By ~ 3

Author(s):

Azza M. Abdelmohsen

Keyword(s):

Bone Mineral Density ◽

Postmenopausal Women ◽

Bone Mineral ◽

Mineral Density ◽

Density Measurements ◽

Peripheral Bone

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Vitamin D and bone mineral density status among postmenopausal Bangladeshi women

IMC Journal of Medical Science ◽

10.3329/imcjms.v12i2.39660 ◽

2019 ◽

Vol 12 (2) ◽

pp. 44-49

Author(s):

AKM Shaheen Ahmed ◽

Wasim Md Mohosin Ul Haque ◽

Khwaja Nazim Uddin ◽

Fadlul Azim Abrar ◽

Farhana Afroz ◽

...

Keyword(s):

Bone Mineral Density ◽

Vitamin D ◽

Postmenopausal Women ◽

Bone Mineral ◽

Age Groups ◽

Urban Hospital ◽

Mineral Density ◽

Cross Sectional ◽

Serum Ipth ◽

Vitamin D Levels

Background and objectives: Low vitamin D is a global problem in all age groups as is osteoporosis in postmenopausal women. The present study was carried out in an urban hospital to assess serum 25-hydroxyvitamin D [25(OH)D] level and bone mineral density (BMD) in postmenopausal women (PMW) and to evaluate correlation between serum 25(OH)D levels and BMD. Methods: A single center cross-sectional study was conducted among 133 apparently healthy PMW aged 45 years and above with the history of complete cessation of menstruation over a period of more than 1 year. Serum 25(OH)D, BMD and serum intact parathyroid hormone (iPTH) were determined. Patients having both vitamin D and BMD values were analyzed for correlations. Similarly, correlation of vitamin D, iPTH and BMD were determined. Results: Among the study population, 63 (47.4%) had deficient (<20 ng/ml), 46 (34.6%) had insufficient (20-30ng/ml) and 24(18%) had sufficient (30-100ng/ml) levels of serum 25(OH)D. Among the 121 patients whose BMD was done, 52 (43.0%) and 60 (49.6%) had osteoporosis and osteopenia respectively. Serum iPTH levels were normal in 34 (89.5%) patients. The proportion of osteopenia and osteoporosis in vitamin D deficient group were 44.1% and 50.8% and in insufficient group 47.5 and 45.0%, respectively. Age had significant negative correlation with BMD value (r=-0.246, p=.005) and significant positive correlation with serum iPTH (r=0.358, p=.024). There was no statistically significant influence of serum 25(OH)D or iPTH on occurrence of osteoporosis (P=0.322 and P=0.592 respectively). Conclusion: A large proportion of postmenopausal women had low vitamin D levels and as well as osteopenia and osteoporosis. Low vitamin D level coexisted with low BMD. However, there was no correlation between serum 25(OH)D levels and BMD status. IMC J Med Sci 2018; 12(2): 44-49

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Prevalence and Risk Factors of Discordance between Left- and Right-Hip Bone Mineral Density Using DXA

ISRN Rheumatology ◽

10.5402/2012/617535 ◽

2012 ◽

Vol 2012 ◽

pp. 1-6 ◽

Cited By ~ 5

Author(s):

Aziza Mounach ◽

Asmaa Rezqi ◽

Imad Ghozlani ◽

Lahsen Achemlal ◽

Ahmed Bezza ◽

...

Keyword(s):

Bone Mineral Density ◽

Bone Mineral ◽

Mineral Density ◽

Detectable Difference ◽

Smallest Detectable Difference ◽

Left And Right ◽

The Difference ◽

Highly Correlated ◽

The Impact ◽

Confounding Parameters

To determine the prevalence of significant left-right differences in hip bone mineral density (BMD), and the impact of this difference on osteoporosis diagnosis, we measured bilateral proximal femora using dual energy X-ray absorptiometry (DXA) in 3481 subjects (608 males, 2873 females). The difference between left and right hip was considered significant if it exceeded the smallest detectable difference (SDD) for any of the three hip subregions. Contralateral femoral BMD was highly correlated at all measuring sites (–0.95). However, significant left-right differences in BMD were common: the difference exceeded the SDD for 54% of patients at total hip, 52.1% at femoral neck, and 57.7% at trochanter. The prevalence of left-right differences was greater in participants >65 years. For 1169 participants with normal spines, 22 (1.9%) had discordant left-right hips in which one hip was osteoporotic; for 1349 patients with osteopenic spines, 94 (7%) had osteoporosis in one hip. Participants with BMI < 20 kg/m2 were more likely to show major T-score discordance (osteoporosis in one hip and normal BMD in the other). Multiple regression analysis showed that the only significant statically parameter that persists after adjusting for all potential confounding parameters were age over 65 years.

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Bone Mineral Density Changes in Patients with Recent-Onset Rheumatoid Arthritis

Clinical Medicine Insights Arthritis and Musculoskeletal Disorders ◽

10.4137/cmamd.s7773 ◽

2011 ◽

Vol 4 ◽

pp. CMAMD.S7773 ◽

Cited By ~ 9

Author(s):

Eman A. Hafez ◽

Howaida E. Mansour ◽

Sherin H. Hamza ◽

Sherine George Moftah ◽

Takwa Badr Younes ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Bone Mineral Density ◽

Bone Mineral ◽

Dual Energy ◽

Mineral Density ◽

X Ray ◽

Recent Onset ◽

Das 28 ◽

Radiological Damage ◽

The Difference

Background Osteoporosis and related fragility fractures are one of the most common complications seen in patients with rheumatoid arthritis (RA) and dramatically affect quality of life. Objective To evaluate changes in bone mineral density in patients with recent onset rheumatoid arthritis (< 1 year) and its correlation if any with a modified DAS-28 score and simple erosion narrowing score (SENS). Methods This study included 30 patients with recent-onset rheumatoid arthritis fulfilling the new American College of Rheumatology/European League Against Rheumatism diagnostic criteria for rheumatoid arthritis and 20 healthy volunteers as controls. All were subjected to a complete blood count, erythrocyte sedimentation rate, C-reactive protein, liver function tests, renal function tests, rheumatoid factor, and plain x-rays of the hands and feet. Dual-energy x-ray absorptiometry DEXA was used to measure bone mineral density (BMD) of the left proximal femur, lumbar spine (L1–L4), and lower distal radius at the time of recruitment. Results In the RA patients, 13.3% had osteoporosis, 50% had osteopenia, and 36.7% had normal BMD. The most common site of osteoporosis was the lumbar spine (four patients, 13.3%) followed by the femur (two patients, 6.6%), and forearm (only one patient, 3.3%). There was a significantly higher percentage of osteoporosis among RA males than females and the difference was statistically significant ( P = 0.009). Osteoporosis was more common in patients treated with corticosteroids and disease modifying antirheumatic drugs (DMARDs) than in patients treated with only nonsteroidal anti-inflammatory drugs ( P = 0.004). Higher disease activity (DAS-28) was found in RA patients with osteoporosis compared to RA patients with normal BMD or osteopenia, but the difference was not statistically significant. Osteoporotic RA patients were found to have a higher SENS score for radiological damage than nonosteoporotic ones. Conclusion BMD changes do occur in patients with early RA, and are not necessarily correlated with disease activity (DAS-28). However, a significant negative correlation was found between BMD and the score of radiological damage (SENS). Dual energy x-ray absorptiometry is an important investigation to assess BMD in early RA patients.

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Parathyroid Hormone and Bone Mineral Density: A Mendelian Randomization Study

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/clinem/dgaa579 ◽

2020 ◽

Vol 105 (11) ◽

Author(s):

Zihao Qu ◽

Fangkun Yang ◽

Jianqiao Hong ◽

Wei Wang ◽

Shigui Yan

Keyword(s):

Bone Mineral Density ◽

Parathyroid Hormone ◽

Bone Mineral ◽

Large Scale ◽

Genome Wide Association Study ◽

Mendelian Randomization ◽

Causal Effect ◽

Age Groups ◽

Mineral Density ◽

Serum Pth

Abstract Purpose Accumulating evidence implicates parathyroid hormone (PTH) in the development of osteoporosis. However, the causal effect of PTH on bone mineral density (BMD) remains unclear. Thus, this study is aimed at exploring the association between the concentrations of serum PTH and BMD. Methods The instrumental variables for PTH were selected from a large-scale genome-wide association study (GWAS; n = 29 155). Outcomes included BMD of the forearm (FA; n = 8143), femoral neck (FN; n = 33 297), lumbar spine (LS; n = 32 735), heel (HL; n = 394 929), and risk of fractures in these bones (n = 361 194). Furthermore, the BMD of 5 different age groups: 15 years or younger (n = 11 807), 15–30 (n = 4180), 30–45 (n = 10 062), 45–60 (n = 18 805), and 60 years or older (n = 22 504) were extracted from a GWAS meta-analysis study. The analyses were performed using the 2-sample Mendelian randomization method. Results Mendelian randomization analysis revealed that the level of serum PTH was inversely associated with BMD of FA (95% CI: -0.763 to -0.016), FN (95% CI: -0.669 to -0.304), and LS (95% CI: -0.667 to -0.243). A causal relationship between serum PTH levels and BMD was observed in individuals aged 30–45 (95% CI: -0.888 to -0.166), 45–60 (95% CI: -0.758 to -0.232), and over 60 years (95% CI: -0.649 to -0.163). Main Conclusions This study demonstrated that the concentrations of serum PTH is inversely associated with BMD of several bones. Further analysis revealed site- and age-specific correlations between serum PTH levels and BMD, which implies that the levels of serum PTH contribute to the development of osteoporosis.

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