Modification of Heterocycles by Amidoalkylation
Keyword(s):
The functionalized derivatives of heterocyclic compounds find extensive application in medicine, agriculture, and many fields of chemistry as precursors for more complex products that display remarkable biological and catalytic activities. A whole range of different heterocycles can be obtained by intra- or intermolecular amidoalkylation. This review presents the examples of successful application of the reactions of C-amidoalkylation, in particular, enantioselective reactions for the modification of heterocycles and outlines the prospects of their further application.