scholarly journals Effect of Narrowband-UVB Phototherapy Treatment on Total Ferroxidase Activity and Ceruloplasmin Oxidase Activity in Sera of Iraqi Vitiligo Patients

2020 ◽  
Vol 4 (2) ◽  
Keyword(s):  
Oxidase Activity ◽  
Narrow Band ◽  
Specific Activity ◽  
The Body ◽  
Ultraviolet B ◽  
Ion Concentration ◽  
Narrowband Uvb ◽  
Before And After ◽  
Ferroxidase Activity ◽  
Uvb Phototherapy

Vitiligo is an acquired pigmentary disorder in which white depigmented macules and patches of skin appear on different parts of the body, affecting all ages and both sexes equally. Focal, segmen-tal, generalized and universal are considered the most characteristic patterns of vitiligo. One of the most effective treatment of this disorder is using light therapy, and in particular ultraviolet (UV) light. Among them narrowband ultraviolet B phototherapy (NB-UVB) is the most widely used. Oxidative stress is considered to be one of the possible pathogenic events in melanocyte loss. Imbalance in the oxidant/antioxidant system have been demonstrated in blood of vitiligo patients. To demonstrate the safety of using NB-UVB phototherapy treatment in vitiligo Iraqi patients. Patients with vitiligo group were treated with NB-UVB regimen as three times weekly on non- consecutive days for a total of 20 sessions (about 2 months). Total ferroxidase (activity and specific activity), ceruloplasmin concentration, ceruloplasmin oxidase (activity and specific activity) and serum copper were determined in all participants before and after NBUVB phototherapy. The above biochemical parameters were measured in serum samples of 30 vitiligo patients before and after treatment with the narrow band UVB phototherapy. NB-UVB treatment was found to be associated with a significant reduction in copper ion concentration, but no significant differences in total ferroxidase (activity and specific activity), ceruloplasmin oxidase (activity and specific activity), and ceruloplasmin concentration. The present results provide evidence which support using narrow band UVB phototherapy as a safe method for vitiligo treatment.

Eruption of bullae within psoriatic plaques: A rare adverse effect of narrow-band ultraviolet B (NB-UVB) phototherapy

2012 ◽  
Vol 18 (6) ◽  
Author(s):  
Kristen Corey ◽  
Nikki A Levin ◽  
Michelle Hure ◽  
April Deng ◽  
Jeffrey Mailhot
Keyword(s):  
Adverse Effect ◽  
Narrow Band ◽  
Ultraviolet B ◽  
Uvb Phototherapy

Immunohistochemical Staining of Surfactant Proteins A and B in Skin of Psoriatic Patients Before and After Narrow-Band UVB Phototherapy

2012 ◽  
Vol 13 (5) ◽  
pp. 341-348 ◽  
Author(s):  
Hayam Abdel Samie Aiad ◽  
Shawky Mahmoud El-Farargy ◽  
Mostafa Mohamed Soliman ◽  
Mohamed Abd El-Wahed Gaber ◽  
Shaymaa Abd El-Aziz Othman
Keyword(s):  
Immunohistochemical Staining ◽  
Narrow Band ◽  
Surfactant Proteins ◽  
Before And After ◽  
Uvb Phototherapy

scholarly journals HMB-45 Study before and after Narrow-Band (311 nm) Ultraviolet B Treatment in Vitiligo

2015 ◽  
Vol 6 (3) ◽  
Author(s):  
Zahra Beigom Moosavi ◽  
Nastaran Ranjbary ◽  
Amin Karimzadeh
Keyword(s):  
Narrow Band ◽  
Ultraviolet B ◽  
Before And After ◽  
Hmb 45

A Short Cycle of Narrow-Band UVB Phototherapy in the Early Phase of Dupilumab Therapy Can Provide a Quicker Improvement of Severe Atopic Dermatitis

Dermatology ◽  
2021 ◽  
pp. 1-9
Author(s):  
Mariateresa Rossi ◽  
Chiara Rovati ◽  
Mariachiara Arisi ◽  
Cesare Tomasi ◽  
Irene Calzavara-Pinton ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Narrow Band ◽  
Ultraviolet B ◽  
Adult Patients ◽  
Severe Atopic Dermatitis ◽  
Treatment Regimens ◽  
Short Course ◽  
Receive Treatment ◽  
Uvb Phototherapy

<b><i>Background:</i></b> Since the best clinical response to dupilumab is achieved after 12–16 weeks, a combination therapy at the beginning of the treatment could be a helpful strategy to reach a faster response in patients with severe atopic dermatitis (AD). <b><i>Objectives:</i></b> To quantify the benefit of a combination of dupilumab treatment with a short course of narrow-band ultraviolet B (NB-UVB) phototherapy. <b><i>Methods:</i></b> In the present pilot study adult patients suffering from severe AD were enrolled with a 2:1 ratio to receive treatment with dupilumab alone or dupilumab plus NB-UVB phototherapy, for 12 weeks. After the twelfth week, all patients received dupilumab only. A follow-up visit took place after 16 weeks. Both clinician-oriented and patient-oriented scores were assessed at baseline (T0) and after 4 (T1), 12 (T2) and 16 (T3) weeks. <b><i>Results:</i></b> Forty-five adult patients were enrolled in the study. Both treatment regimens were well tolerated and very effective on all measured scores (EASI, SCORAD, BSA, NRS of itching, NRS of sleep loss, DLQI, POEM and HADS), but the combined regimen led to a more robust clinical improvement of lesions and relief of symptoms after 4 weeks. However, after 12 and 16 weeks, the additional therapeutic effect of phototherapy weakened. <b><i>Conclusion:</i></b> NB-UVB phototherapy can provide a faster remission of severe AD in the first few weeks of dupilumab therapy.

Therapeutic implications of C‐reactive protein and uric acid in patients with psoriasis before and after narrow band ultraviolet B therapy

2020 ◽  
Vol 33 (6) ◽  
Author(s):  
Mamoun Shalaby ◽  
Ahmad Elshahid ◽  
Ahmed Metwaly ◽  
Ayda Ibrahim ◽  
Mohammad Jafferany ◽  
...  
Keyword(s):  
Uric Acid ◽  
Narrow Band ◽  
Ultraviolet B ◽  
C Reactive Protein ◽  
Therapeutic Implications ◽  
Reactive Protein ◽  
Before And After
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