Immunohistochemical Staining of Surfactant Proteins A and B in Skin of Psoriatic Patients Before and After Narrow-Band UVB Phototherapy

2012 ◽  
Vol 13 (5) ◽  
pp. 341-348 ◽  
Author(s):  
Hayam Abdel Samie Aiad ◽  
Shawky Mahmoud El-Farargy ◽  
Mostafa Mohamed Soliman ◽  
Mohamed Abd El-Wahed Gaber ◽  
Shaymaa Abd El-Aziz Othman
Keyword(s):  
Immunohistochemical Staining ◽  
Narrow Band ◽  
Surfactant Proteins ◽  
Before And After ◽  
Uvb Phototherapy

scholarly journals Effect of Narrowband-UVB Phototherapy Treatment on Total Ferroxidase Activity and Ceruloplasmin Oxidase Activity in Sera of Iraqi Vitiligo Patients

2020 ◽  
Vol 4 (2) ◽  
Keyword(s):  
Oxidase Activity ◽  
Narrow Band ◽  
Specific Activity ◽  
The Body ◽  
Ultraviolet B ◽  
Ion Concentration ◽  
Narrowband Uvb ◽  
Before And After ◽  
Ferroxidase Activity ◽  
Uvb Phototherapy

Vitiligo is an acquired pigmentary disorder in which white depigmented macules and patches of skin appear on different parts of the body, affecting all ages and both sexes equally. Focal, segmen-tal, generalized and universal are considered the most characteristic patterns of vitiligo. One of the most effective treatment of this disorder is using light therapy, and in particular ultraviolet (UV) light. Among them narrowband ultraviolet B phototherapy (NB-UVB) is the most widely used. Oxidative stress is considered to be one of the possible pathogenic events in melanocyte loss. Imbalance in the oxidant/antioxidant system have been demonstrated in blood of vitiligo patients. To demonstrate the safety of using NB-UVB phototherapy treatment in vitiligo Iraqi patients. Patients with vitiligo group were treated with NB-UVB regimen as three times weekly on non- consecutive days for a total of 20 sessions (about 2 months). Total ferroxidase (activity and specific activity), ceruloplasmin concentration, ceruloplasmin oxidase (activity and specific activity) and serum copper were determined in all participants before and after NBUVB phototherapy. The above biochemical parameters were measured in serum samples of 30 vitiligo patients before and after treatment with the narrow band UVB phototherapy. NB-UVB treatment was found to be associated with a significant reduction in copper ion concentration, but no significant differences in total ferroxidase (activity and specific activity), ceruloplasmin oxidase (activity and specific activity), and ceruloplasmin concentration. The present results provide evidence which support using narrow band UVB phototherapy as a safe method for vitiligo treatment.

scholarly journals A multispectral 3D-Endoscope for Cholesteatoma Removal

2020 ◽  
Vol 6 (3) ◽  
pp. 257-260
Author(s):  
Eric L. Wisotzky ◽  
Jean-Claude Rosenthal ◽  
Anna Hilsmann ◽  
Peter Eisert ◽  
Florian C. Uecker
Keyword(s):  
Multispectral Imaging ◽  
Narrow Band ◽  
Tissue Classification ◽  
Step Size ◽  
3D Endoscope ◽  
Before And After ◽  
Overlay Technique ◽  
Ct Data ◽  
Metric Dimensions ◽  
20 Nm

AbstractWe present a stereo-multispectral endoscopic prototype using a filter-wheel to guide the removal of cholesteatoma tissue in the middle ear. An image-based method is used that combines multispectral tissue classification for the detection of tissue to be removed and 3Dreconstruction to determine its metric dimensions. The multispectral illumination used for tissue classification ranges from λ = 400 nm to λ = 500 nm with step-size of 20 nm, which results in six different narrow-band illumination modes. For classical RGB imaging and metric calculations, a broadband illumination mode is applied before and after the narrow-band illumination. The spectral information is augmented into the broadband mode using an overlay technique. The combination of multispectral imaging with stereoscopic 3D-reconstruction results in new valuable visualization of intraoperative data. This allows to generate a 3D-model of the patients anatomy highlighting the identified malicious tissue and compare the anatomical dimensions with pre-operative CT data.

Eruption of bullae within psoriatic plaques: A rare adverse effect of narrow-band ultraviolet B (NB-UVB) phototherapy

2012 ◽  
Vol 18 (6) ◽  
Author(s):  
Kristen Corey ◽  
Nikki A Levin ◽  
Michelle Hure ◽  
April Deng ◽  
Jeffrey Mailhot
Keyword(s):  
Adverse Effect ◽  
Narrow Band ◽  
Ultraviolet B ◽  
Uvb Phototherapy

scholarly journals EVALUATION OF NARROW-BAND UVB PHOTOTHERAPY FOR VITILIGO

2013 ◽  
Vol 2 (44) ◽  
pp. 8591-8598
Author(s):  
Girish P.N ◽  
Narendra J. Shetty ◽  
Vinma H. Shetty ◽  
Sandhya I ◽  
Umananda Mallya ◽  
...  
Keyword(s):  
Narrow Band ◽  
Uvb Phototherapy

scholarly journals White opaque substance visualized by magnifying narrow-band imaging is associated with intragastric acid conditions

2018 ◽  
Vol 06 (07) ◽  
pp. E830-E837 ◽  
Author(s):  
Kazumi Togo ◽  
Tetsuya Ueo ◽  
Kenshi Yao ◽  
Kurato Wada ◽  
Hideho Honda ◽  
...  
Keyword(s):  
Gastric Juice ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Lipid Absorption ◽  
Before And After ◽  
Strong Acidity ◽  
Intragastric Acid ◽  
H Pylori ◽  
Ph Level ◽  
The Relationship

Abstract Background and study aims The presence of white opaque substance (WOS) is an endoscopic marker of intestinal metaplasia. Considering that the nature of WOS is absorbed lipid droplets, lipase plays an important role in the lipid absorption process and is inactivated at strong acidity. WOS may only be present in a hypochlorhydria state following Helicobacter pylori infection, and, thus, may not be highly sensitive marker, especially in H. pylori-eradicated patients. We investigated the relationship between WOS and gastric acid conditions. Patients and methods A total of 501 patients were retrospectively evaluated for the presence of WOS at 2 regions of interest using magnifying narrow-band imaging. The pH level of collected gastric juice was also measured. Study end points were (1) prevalence of WOS and its relationship with gastric juice pH in 3 groups: H. pylori-uninfected, H. pylori-infected, and H. pylori-eradicated; (2) the relationship between prevalence of WOS and gastric juice pH before and after proton pump inhibitor (PPI) administration in 29 H. pylori-eradicated cases. Results Prevalence of WOS was 0 % (0 /206), 28.4 % (31/109), and 3.2 % (6/186) in the H. pylori-uninfected, H. pylori-infected, and H. pylori-eradicated groups, respectively. Mean gastric juice pH was significantly higher in WOS-positive cases than in WOS-negative cases in the H. pylori-infected and H. pylori-eradicated groups (P < 0.0001). Mean gastric juice pH increased from 1.1 to 6.9 after PPI administration and WOS prevalence increased from 0 % (0/29) to 45 % (13/29) of cases. Conclusion The prevalence of WOS is closely associated with the neutralization of intragastric pH.

Effect of Narrow- band UVB on serum and tissue vitamin D level in vitiligo

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Ali Abdulkareem Al-Shabkhon ◽  
Adel Ahmed Halim Emam ◽  
Ahmed Abd Elfattah Afify
Keyword(s):  
Vitamin D ◽  
Case Control Study ◽  
Narrow Band ◽  
Tissue Level ◽  
Before And After ◽  
Duration Of Disease ◽  
The Mean ◽  
Tissue Vitamin ◽  
Control Study

Abstract Background Immunologic background of vitiligo, role of vitamin D on its pathogenesis, role of NB-UVB on its treatment and its stimulatory effect NB-UVB on VDR expression are challenging area of research. The current study will focus on evaluating the effect of NB-UVB on serum and tissue level of vitamin D in vitiligo patients and correlating it with the degree of improvement. Aim of the study The aim of the present study is to evaluate and compare the serum and tissue vitamin D level in vitiligo patients before and after NB- UVB therapy and correlate them together and with the degree of improvement. Patients and methods A case-control study included 16 vitiligo patients and 16 age and sex matched healthy controls. All patients will be examined by one dermatologist (demonstrating the extent of depigmentation according to rule of nines), and photographs will be taken before and after phototherapy to be evaluated by two different dermatologists to document the extent of repigmentation. Estimation of serum level of vitamin D by ELISA Results Five of the 15 patients achieved more than 55% repigmentation; the mean duration of disease was 13 months. The remaining 10 patients had 30% - 40% repigmentation.

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