scholarly journals Clinical and experimental justifi cation for the use of high-frequency electrocoagulator EK-300M1 for the surgical treatment of breast tumors in female dogs

2020 ◽  
pp. 129-139
Author(s):  
S. Rublenko ◽  
A. Yaremchuk ◽  
V. Vlasenko
Keyword(s):  
Breast Cancer ◽  
Surgical Treatment ◽  
Postoperative Period ◽  
High Frequency ◽  
Breast Tumors ◽  
Early Postoperative Period ◽  
Surgical Removal ◽  
Duration Of Treatment ◽  
Objective Criterion ◽  
Endogenous Intoxication

Modern medical practice shows that the only eff ective treatment for breast cancer in dogs is surgery; current developments in chemotherapy and radiation therapy are ineff ective and too expensive. To identify the types of breast tumors and their anatomical distribution, it is necessary to have a reliable histological diagnosis. In most cases, it is used because the main treatment for breast cancer in dogs is their surgical removal. Undoubtedly decisive for this method of treatment are the phenomena of intoxication and endotoxicosis. Endotoxicosis in the early postoperative period consists of iatrogenic, tumor with tumors isolated and based on a small number of observations. However, the results of intoxication and the consequences of massive surgical tissue damage are often a determining factor for the outcome of treatment. Unfortunately, reports of studies of MSM in animals obtained by us indicate that almost all animals with breast tumors have endogenous intoxication, which we detected by the level of MSM and MDA in blood plasma. In our opinion, determination of the level of these markers of endotoxicosis before surgery and in the postoperative period can be an objective criterion for the risk of surgical treatment. Monitoring the level of MSM in the remote postoperative period, in combination with other biochemical studies can be a criterion for assessing the general clinical condition of the animal for the development of metastases. Probably lower levels of endogenous intoxication and clinically confi rmed reduction in the duration of treatment are a clear confi rmation of the eff ectiveness of high-frequency electrocoagulator EK-300M1. Dogs with breast tumors had high levels of MSM and MDA, which is a refl ection of the level of endogenous intoxication and may be an objective criterion for the risk of surgical treatment and postoperative recovery. Progressive reduction of these indicators in animals of the experimental group proves the eff ectiveness of the proposed treatment tactics. Key words: tumors, electrocoagulator EK-300M1, mastectomy, female dogs, oncology, endogenous intoxication, wound healing.

scholarly journals Neuropsychological features of patients of reproductive age diagnosed with breast cancer at the stage of surgical treatment using xenon-oxygen therapy

2021 ◽  
Vol 8 (3) ◽  
pp. 10-20
Author(s):  
D. A. Rozenko ◽  
A. I. Shikhlyarova ◽  
L. N. Vaschenko ◽  
N. N. Popova ◽  
Yu. Yu. Arapova ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Surgical Treatment ◽  
Postoperative Period ◽  
Oxygen Therapy ◽  
Early Postoperative Period ◽  
Reproductive Age ◽  
Control Group ◽  
Newly Diagnosed ◽  
Beta Rhythm ◽  
Psychophysiological State

Purpose of the study. To study functional changes in the neuropsychological status of reproductive age patients with newly diagnosed breast cancer and to assess the possibility of using xenon-oxygen therapy to correct disorders.Patients and methods. This study included 60 reproductive age patients with newly diagnosed breast cancer who were undergoing surgical treatment at the Department of Bone, Skin, Soft Tissue and Breast Tumors of the National Medical Research Centre for Oncology of the Ministry of Health of Russia from 2018 to 2020. The main group included 30 patients with breast cancer diagnosed at the surgical stage of combined treatment, who underwent a rehabilitation course of xenon-oxygen therapy in the early postoperative period. The control group was formed from patients with the same diagnosis, without the use of this therapy. The functional state of the central nervous system in all patients was assessed by the parameters of the electroencephalography (EEG) bioelectrical activity. For the final assessment of the physiological and psychological state of the patients, a standardized questionnaires of the quality of life – ESAS, MOS-SF‑36, were used. Statistical data processing was performed using the Statistica 10 software package. Results. During the study, statistically significant differences were found in the assessment of subjective indicators, so in the group of patients using xenon-oxygen therapy, there was an improvement in well-being by 2.6 times, a decrease in depression by 2.3 times, a decrease in symptoms of nausea by 3 times, anxiety 1.9 times (p < 0.05). Against the background of an improvement in the psychophysiological state, the EEG showed a significant increase in the power of slow delta and theta rhythms, an increase in the power of the alpha rhythm and a decrease in the power of the beta rhythm, while in the patients of the control group only a decrease in the power of the beta rhythm was noted.Conclusion. The early postoperative period in patients with newly diagnosed breast cancer is characterized by the formation of a depressive symptom complex. The use of a course of xenon-oxygen therapy contributes to the normalization of the subjective feeling of physical and psychological health, increasing vital and social activity. Changes in the indicators of brain bioelectric activity and an improvement in psychophysiological state occur against the background of changes in brain activity caused by the normalizing effect of xenon.

Results of minimally invasive treatment of scar degeneration of palmar aponeurosis

2021 ◽  
pp. 31-38
Author(s):  
Natal’ya Fedosova ◽  
Andrey Abramenkov ◽  
Igor Ezhov
Keyword(s):  
Chronic Disease ◽  
Surgical Treatment ◽  
Minimally Invasive ◽  
Postoperative Period ◽  
Dupuytren’S Contracture ◽  
Working Population ◽  
Duration Of Treatment ◽  
Invasive Treatment ◽  
Dupuytren's Contracture ◽  
Palmar Aponeurosis

An analysis of the results of surgical treatment of patients with Dupuytren’s contracture using tactics of minimally invasive percutaneous aponeurotomy and open aponeurectomy is presented. Dupuytren’s contracture (CD) is a chronic disease characterized by cicatricial degeneration of the palmar aponeurosis with a predominant lesion of the working population. The need to quickly restore the function of the upper limb in the postoperative period in patients with CD leads to the need to develop new and modernize the existing minimally invasive tactics of surgical treatment, allowing to minimize the duration of treatment and the risks of various complications.

Acceptance of Illness after Surgery in Patients with Breast Cancer in the Early Postoperative Period

2015 ◽  
Vol 87 (11) ◽  
Author(s):  
Andrzej Nowicki ◽  
Elżbieta Krzemkowska ◽  
Piotr Rhone
Keyword(s):  
Breast Cancer ◽  
Postoperative Period ◽  
Early Period ◽  
Conservative Surgery ◽  
Early Postoperative Period ◽  
Economic Situation ◽  
White Collar Workers ◽  
Acceptance Of Illness ◽  
High Level ◽  
Type Of Surgery

AbstractThe breast cancer is the most common cancer in women, both in Poland and in the world. Consequences entail a disruption in the physical, psychological and social functioning.was to assess the acceptance of illness by patients treated for breast cancer in the early postoperative period.The research was conducted on the group of 100 consecutive patients aged 32-80 years (median 56 years) who underwent surgery for breast cancer in the Centre of Oncology in Bydgoszcz w 2014 roku. 68 of women had mastectomy, 32 of women had conservative surgery. Polling was conducted in the early period after surgery. The original questionnaire containing closed questions the scale of acceptance of the disease (AIS) as well as mental adaptation to cancer (Mini-Mac) was used in the study.38% of patients had high acceptance of the disease, 48% averageand 14% had low acceptance. Patients after conservative surgery had a higher average values for the mental strategies to cope with the disease, for the fighting spirit (23.1), helplessness and hopelessness (13.5), positive revaluation (23), the patients had a lower average (16.5) in the strategy to absorb anxiety. Patients after conservative surgery had a higher average for constructive style (2.6) but lower for destructive style (1.5). High level of mental coping with the disease was observed in 53%of patients with constructive style and 4% of patients with destructive style. While, a low level of mental coping with the dosease was observed in 5% of patients with constructive style and 46% of patients with destructive style.Almost half of women after mastectomy or conservative surgery had an average acceptance of the disease. The disease was accepted best by educated women living in the cities, white-collar workers with a good economic situation. The following factors were affected the better management of the disease, in order: age, education, current occupation and economic situation, while the type of surgery did not affect better management. More than half of women, regardless of the type of surgery reflected the high level of constructive style.

Seizures after evacuation of subdural hematomas: incidence, risk factors, and functional impact

2010 ◽  
Vol 112 (2) ◽  
pp. 455-460 ◽  
Author(s):  
Alejandro A. Rabinstein ◽  
Seung Young Chung ◽  
Leslie A. Rudzinski ◽  
Giuseppe Lanzino
Keyword(s):  
Surgical Treatment ◽  
Functional Outcome ◽  
Functional Impairment ◽  
Postoperative Period ◽  
Strong Association ◽  
Early Postoperative Period ◽  
Acute Subdural Hematoma ◽  
Early Functional Outcome ◽  
Gcs Score

Object The purpose of this study was to evaluate the incidence of seizures or epileptiform abnormalities on electroencephalography (EEG) studies in patients undergoing surgical treatment for acute subdural hematoma (SDH). Methods This was a retrospective study of 134 consecutive patients with acute or acute-on-chronic SDH who underwent surgical treatment at the authors' institution between January 2004 and July 2008. Detailed information was collected regarding baseline clinical data (including preexistent functional impairment); Glasgow Coma Scale (GCS) sum scores before and 24 hours after surgery; presence of clinical seizures; EEG findings; and functional outcome on discharge and up to the 6-month follow-up. All brain CT scans were reviewed to calculate SDH volume and midline shift. The Glasgow Outcome Scale (GOS) score was used for functional assessment, and GOS scores of 1–3 were considered indicative of poor outcome. Univariate and multivariate logistic regression analyses were performed to identify statistical associations. Results Clinical seizures or epileptiform changes on EEG were observed during the acute postoperative period in 33 patients (25%). Preexistent functional impairment and seizures/epileptiform EEG findings after surgery were independently associated with poor functional outcome upon hospital discharge (p < 0.001 for both). Preexistent functional impairment (p < 0.001), lower GCS score before surgery (p = 0.04), and lower GCS score 24 hours after surgery (p = 0.007), but not seizures/epileptiform EEG findings, were independently associated with poor functional recovery at 1- to 6-month follow-up evaluations. Seizures/epileptiform EEG findings had a strong association with lower GCS scores after surgery (p = 0.01), and they were more common in patients who underwent evacuation by craniotomy (p = 0.02). Conclusions Epileptic complications are common after acute SDH evacuation, and should be suspected in patients with an unanticipated depressed level of consciousness after surgery. Seizures worsen early functional outcome, but delayed favorable recovery is possible. Therefore, one should be cautious when discussing prognosis in the early postoperative period of patients with epileptic complications.

scholarly journals SURGICAL TREATMENT OF CAROTID STENOSIS IN PATIENTS WITH CORONARY HEAR+T DISEASE IN ORDER TO PREVENT ISCHEMIC STROKE

2020 ◽  
pp. 124-126
Author(s):  
I. S. Pulyaeva ◽  
V. A. Prasol
Keyword(s):  
Ischemic Stroke ◽  
Surgical Treatment ◽  
Carotid Stenosis ◽  
Postoperative Period ◽  
Stable State ◽  
Length Of Hospital Stay ◽  
Early Postoperative Period ◽  
Main Stage ◽  
Simultaneous Operations ◽  
Ischemic Attack

Summary. Goal. To analyze the results of surgical treatment of carotid stenosis in patients with coronary heart disease in order to prevent ischemic stroke. Materials and methods. The analysis included 18 patients treated in the SI «V. T. Zaitseva IGUS of NAMNU» from 2017 to 2019 in combined atherosclerotic lesions of the coronary and carotid arteries which evaluated the reserve brain. Results and discussion. All patients with two-stage treatment of the first and second groups were discharged in a stable state, one had a clinic of transient ischemic attack in the postoperative period. Conclusions. Simultaneous operations are advisable in patients with a reduced reserve of both coronary and cerebral circulation. The risk of developing cerebral and cardiac postoperative complications is comparable with the results of phased operations, reducing the length of hospital stay of the patient. The results of the hypoxic test serve as an additional criterion for the decision to impose an internal intra-arterial shunt. This allows you to reduce the time of the main stage of carotid endarterectomy and to avoid additional possible complications in the early postoperative period.

scholarly journals Low-intensity low-frequency magnetotherapy in the early postoperative period in patients with breast cancer

2020 ◽  
Vol 17 (5) ◽  
pp. 233-240
Author(s):  
Inna S. Evstigneeva ◽  
Marina Yu. Gerasimenko
Keyword(s):  
Breast Cancer ◽  
Surgical Treatment ◽  
Upper Limb ◽  
Low Frequency ◽  
Pain Syndrome ◽  
Early Postoperative Period ◽  
Advanced Technique ◽  
Low Intensity ◽  
Extended Technique

Background. Rehabilitation of patients after radical treatment of breast cancer is especially relevant due to the fact that successes in diagnostics and treatment of this disease in recent years have led to an increase in the life expectancy of female patients. Aim. to compare the efficiency of various methods of low-frequency low-intensity magnetotherapy in patients operated on for breast cancer, in the early terms (24 days) after surgery. Methods. Objective and instrumental examination was performed in 78 patients after radical surgical treatment of breast cancer in the early stages (24 days) after surgery. All patients received a course of low-frequency low-intensity magnetotherapy. Results. When applying the extended technique (the effect on the segmental-reflex region and upper limb from the side of the surgery), patients noted an improvement in the quality of life, a decrease in swelling of the upper limb, and a decrease in pain syndrome. A decrease in the number of postoperative complications and the duration of lymphorrhea was noted. Conclusion. Thus, the use of various methods of low-frequency low-intensity magnetotherapy is advisable to use in the early terms (24 days) after surgical treatment, however, the use of the advanced technique provides high function capabilities and enables to get a more pronounced and lasting clinical result.

scholarly journals Secondary neurological outcomes in patients with brachiocephalic and coronary artery disease in the early postoperative period after simultaneous and hybrid surgical treatment

2021 ◽  
Vol 10 (4) ◽  
pp. 58-67
Author(s):  
O. V. Maleva ◽  
O. A. Trubnikova ◽  
I. V. Таrasova ◽  
S. V. Ivanov ◽  
O. L. Barbarash
Keyword(s):  
Coronary Artery ◽  
Surgical Treatment ◽  
Postoperative Period ◽  
Postoperative Cognitive Dysfunction ◽  
Early Postoperative Period ◽  
Brachiocephalic Artery ◽  
Neurological Outcomes ◽  
Simultaneous Surgery ◽  
Artery Disease ◽  
Hybrid Group

Aim. To compare secondary neurological outcomes in patients with brachiocephalic and coronary artery disease in the early postoperative period after different surgical treatment strategies (simultaneous and hybrid).Methods. Secondary neurological outcomes were evaluated in 43 patients with coronary and brachiocephalic artery disease in the early postoperative period after (1) carotid endarterectomy and on-pump coronary artery bypass surgery; (2) percutaneous coronary intervention and carotid endarterectomy. Demographic, clinical, instrumental data were collected. Neuropsychological assessment was performed using the Mini-Mental State Examination and Frontal Assessment Battery. Memory, attention and neurodynamics were measured using the “Status-PF” software at days 2–3 before the surgery and at days 5–7 after it. The presence of postoperative cognitive dysfunction was estimated on the basis of criteria defined as a 20% decline on 20% of the tests. Statistical analysis was performed using the software package “Statistica 10.0”.Results. Patients who underwent hybrid intervention demonstrated improved attention and memory in the early postoperative period. Complex visual-motor reaction significantly increased in patients after simultaneous surgery. Attention differed significantly in both groups. Thus, patients from the hybrid group processed more characters per 1 and 4 minutes while completing the Bourdon proof reading test. The total number of processed characters prevailed in the hybrid group. Cognitive processing speed was higher in the hybrid group according to the brain performance test. The incidence of early postoperative cognitive dysfunction was 60% in patients after simultaneous surgery and 11% in patients after hybrid surgery (p = 0.006, OR±SE 12.5±3.2).Conclusion. Hybrid intervention has shown its superiority over simultaneous intervention in terms of low rate of early cognitive impairment, thereby confirming the necessity to take into account the obtained results while selecting the optimal surgical treatment in patients with coronary and brachiocephalic artery disease present with cognitive deficits at baseline.

scholarly journals РЕЗУЛЬТАТЫ ХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ ПАЦИЕНТОК С ПЕРВИЧНЫМ РАКОМ ГРУДНОЙ ЖЕЛЕЗЫ

World Science ◽  
2019 ◽  
Vol 1 (7(47)) ◽  
pp. 48-50
Author(s):  
Макаров В. В. ◽  
Цивенко А. И. ◽  
Королевская А. Ю.
Keyword(s):  
Breast Cancer ◽  
Postoperative Period ◽  
Radical Surgery ◽  
Postoperative Mortality ◽  
Disease Recurrence ◽  
Early Postoperative Period ◽  
Treatment Results ◽  
Surgical Interventions ◽  
Postoperative Wound ◽  
Primary Radical

The treatment results of 172 patients with breast cancer, who underwent radical surgery on the breast, were analyzed. During the last 4 years, the implementation of combined surgical interventions — radical surgery with removal of the tumor with D2 lymphnode dissection and the simultaneous installation of a silicone implant (in 17 patients — 17.4%) takes attention. In most cases, the early postoperative period proceeded safely. During the early postoperative period, complications occurred in 30 (17.4%) patients: long postoperative lymphorrhea - 25 (14.5%) cases, which in 6 (3.6%) patients leaded to the development of seroma, and in two (1.2 %) of them - suppuration of the postoperative wound. Diastasis of wound edges was noted in 4 (2.3%) patients. In 1 (0.6%) case, bleeding was observed on the first day after surgery. Postoperative mortality rate was 0%. 10 (5.8%) patients were admitted for the surgery during the period from 1 to 3 years after the primary radical surgery due to a local recurrence of breast cancer. Despite the arsenal of modern diagnostic, anesthetic and surgical support, the issue of postoperative complications prevention and the disease recurrence prevention of the patients with breast cancer remains relevant.

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