scholarly journals UV-Vis Spectrophotometry Observation to Find Appropriate Wavelength for Non-Invasive Blood Haemoglobin Level Measurement Optical Device

2021 ◽  
Vol 12 (2) ◽  
pp. 1927-1934
Keyword(s):  
Functional Group ◽  
Healthy Adult ◽  
Pearson Correlation ◽  
Hemoglobin Level ◽  
Optical Device ◽  
Non Invasive ◽  
Level Measurement ◽  
Blood Hemoglobin ◽  
Blood Haemoglobin ◽  
Ethical Clearance

The wavelength convention for non-invasive blood hemoglobin measurement remains inconclusive. This experimental observation to find the appropriate wavelength candidate of LED for non-invasive blood hemoglobin level measurement optical device in 200 nm to 900 nm range. This observation ran in Prodia Kedoya and Biochemistry Lab, Universitas Krida Wacana, West Jakarta, in July 2019. The blood samples were obtained from 10 randomly selected consenting non blinded, healthy adult subjects between 18 and 60 years old. Each blood sample was diluted using double distilled water and measured absorbance using UV-Vis Spectrophotometry. Then it compared to blood hemoglobin level by standard gold measurement from Prodia Kedoya. The result shows functional group found in human Hb is C=O. Appropriate wavelengths were obtained based on the Pearson correlation, standard deviation, and human skin pigment, which are 525 nm, 550 nm, and 570 nm. Then the measurement of Hb levels is carried out at the selected wavelength and processed using a ZunZunSite3 to get the mapping data of Hb level from ten respondents. Root mean square error from the measurement. The error obtained is minimal, which indicates that the wavelength used is suitable for measuring the Hb level. Ethical Clearance: 076/IT3.KEPMSM-IPB/SK/2018.

scholarly journals Review on wavelength for non-invasive blood hemoglobin level measurement optical device

2019 ◽  
Author(s):  
Renan Prasta Jenie ◽  
Umu Nasiba ◽  
Ika Rahayu ◽  
Naufal Muharram Nurdin ◽  
Irzaman Husein ◽  
...  
Keyword(s):  
Hemoglobin Level ◽  
Optical Device ◽  
Non Invasive ◽  
Level Measurement ◽  
Blood Hemoglobin

scholarly journals Review: Non-invasive blood haemoglobin level measurement

2021 ◽  
Author(s):  
Irzaman ◽  
Yaya Suryana ◽  
Sabar Pambudi ◽  
Tika Widayanti ◽  
Renan Prasta Jenie ◽  
...  
Keyword(s):  
Haemoglobin Level ◽  
Non Invasive ◽  
Level Measurement ◽  
Blood Haemoglobin

Non-Invasive Hemoglobin Estimation in Patients with β-Thalassemia Major

Blood ◽  
2012 ◽  
Vol 120 (21) ◽  
pp. 5179-5179
Author(s):  
Murtadha K. Al-Khabori ◽  
Arwa Z. Al-Riyami ◽  
Mohammed Al-Huneini ◽  
Khalil Al Farsi ◽  
Abdulhakeem Al-Hashim ◽  
...  
Keyword(s):  
Correlation Coefficient ◽  
Conflicts Of Interest ◽  
Pearson Correlation ◽  
Tertiary Care ◽  
Thalassemia Major ◽  
Primary Objective ◽  
Hemoglobin Level ◽  
Coefficient Of Determination ◽  
Care Hospital ◽  
Non Invasive

Abstract Abstract 5179 Introduction: Patients with β-thalassemia major receive regular blood transfusions. Non-invasive hemoglobin (Hb) estimation may simplify their care. Masimo Pronto-7 Pulse CO-oximetry device is used to non-invasively estimate the hemoglobin level but has not been previously validated in this group of patients. The primary objective of this study was to validate the pulse CO-oximetry based hemoglobin estimation in children and adults with thalassemia major. Methods: We conducted a prospective observational study on 108 children and adults with thalassemia major attending the daycare thalassemia center of a tertiary care hospital over 6 weeks. We estimated a spot Hemoglobin (Sp Hb) level using Masimo Pronto-7 Pulse CO-oximetry device (two measurements per patient) and compared it to a venous sample Hb (Reference Hemoglobin; Ref Hb) measured using Abbott CELL-DYN Sapphire hematology analyzer. We calculated Pearson correlation coefficient and coefficient of determination (R2). The multivariable linear regression model of predicting the estimation differences included age, gender, weight, height, blood pressure and reference hemoglobin. Results: We enrolled 108 patients (54 males, 54 females) with a mean age of 21. 6 years (SD 7. 3; 2. 5–38). There were 156 estimation episodes. The mean Ref Hb and SpHb were 9. 4 g/dL (SD 0. 9; 7. 1–12. 3) and 11. 1 g/dL (SD 1. 2; 7. 5–14. 7) respectively. The correlation coefficient between the Sp Hb and Ref Hb was 0. 49 (R2 = 24%) with a mean difference of 1. 7 g/dL (SD 1. 1; −1. 2 to 4. 3). In the multivariable model, Ref Hb level was the only statistically significant predictor of the difference in measurement (p =0. 002). There was a strong correlation between the two CO-oximetry Hb measurements (correlation coefficient 0. 70, R2 = 50%). Conclusions: Our results indicate that Masimo Pronto-7 Pulse CO-oximetry device overestimates the hemoglobin level and it cannot be recommended for patients with thalassemia major. Larger prospective studies are needed to confirm these results. Disclosures: No relevant conflicts of interest to declare.

scholarly journals Effect of maternal anemia on cord blood haemoglobin of newborn

2021 ◽  
Vol 11 (1) ◽  
pp. 64
Author(s):  
Richa Rathoria ◽  
Ekansh Rathoria
Keyword(s):  
Cord Blood ◽  
Correlation Coefficient ◽  
Pearson Correlation ◽  
P Value ◽  
Pearson Correlation Coefficient ◽  
Maternal Anemia ◽  
New Born ◽  
Blood Hemoglobin ◽  
Blood Haemoglobin ◽  
The Mean

Background: Anemia during pregnancy is linked to major maternal and fetal problems. The aim of the study was to find any correlation between maternal anemia and neonatal cord blood haemoglobin (Hb) levels.Methods: This cross-sectional study was done in the department of pediatrics and department of obstetrics and gynaecology at the Hind Institute of Medical Sciences, Barabanki over 9 months from January 2021 to September 2021. A total of 308 pregnant females more than 34 weeks of gestation who delivered participated in the study and cord blood hemoglobin of their new-born was collected. The mean maternal hemoglobin and mean cord blood hemoglobin were compared using the Pearson correlation coefficient in different groups i.e., non-anemic, anemic, mild, moderate, and severe anemic groups.  Results: Out of 308 pregnant women, 198 (64.3%) were anemic, and 110 (35.7%) were nonanemic. The mean maternal hemoglobin among non-anemic mothers and anemic mothers was 11.91 (0.70) and 9.14 (1.56) respectively. The Pearson correlation coefficient of non-anemic, anemic, mild, moderate, and severe anemic groups were 0.6985, 0.8453, 0.7772, 0.6321, and 0.7226 respectively with a statistically significant p value<0.05 showing a positive correlation between maternal hemoglobin and cord hemoglobin.Conclusions: From this study, we concluded that maternal anemia affects neonatal cord blood hemoglobin. According to the findings, anemic women deliver new-born with lower hemoglobin levels than non-anemic mothers. The findings revealed a linear correlation between maternal hemoglobin and cord blood hemoglobin of their new-born. 

A System for Non-invasive Assessment of Blood Hemoglobin Level in Screening Tests

2017 ◽  
Vol 51 (2) ◽  
pp. 93-96 ◽  
Author(s):  
V. N. Konyukhov ◽  
V. P. Zakharov ◽  
I. L. Davydkin ◽  
N. S. Kozlova ◽  
P. I. Bakhtinov ◽  
...  
Keyword(s):  
Hemoglobin Level ◽  
Screening Tests ◽  
Non Invasive ◽  
Blood Hemoglobin

Relationship between Invasive and Non-Invasive Hemodynamic Measures in Experimental Pulmonary Hypertension

2020 ◽  
Vol 16 (1) ◽  
pp. 47-53
Author(s):  
Vicente Benavides-Córdoba ◽  
Mauricio Palacios Gómez
Keyword(s):  
Heart Rate ◽  
Pulmonary Hypertension ◽  
Ejection Fraction ◽  
Right Ventricle ◽  
Correlation Coefficient ◽  
Pearson Correlation ◽  
Systolic Pressure ◽  
Control Group ◽  
Pearson Correlation Coefficient ◽  
Non Invasive

Introduction: Animal models have been used to understand the pathophysiology of pulmonary hypertension, to describe the mechanisms of action and to evaluate promising active ingredients. The monocrotaline-induced pulmonary hypertension model is the most used animal model. In this model, invasive and non-invasive hemodynamic variables that resemble human measurements have been used. Aim: To define if non-invasive variables can predict hemodynamic measures in the monocrotaline-induced pulmonary hypertension model. Materials and Methods: Twenty 6-week old male Wistar rats weighing between 250-300g from the bioterium of the Universidad del Valle (Cali - Colombia) were used in order to establish that the relationships between invasive and non-invasive variables are sustained in different conditions (healthy, hypertrophy and treated). The animals were organized into three groups, a control group who was given 0.9% saline solution subcutaneously (sc), a group with pulmonary hypertension induced with a single subcutaneous dose of Monocrotaline 30 mg/kg, and a group with pulmonary hypertension with 30 mg/kg of monocrotaline treated with Sildenafil. Right ventricle ejection fraction, heart rate, right ventricle systolic pressure and the extent of hypertrophy were measured. The functional relation between any two variables was evaluated by the Pearson correlation coefficient. Results: It was found that all correlations were statistically significant (p <0.01). The strongest correlation was the inverse one between the RVEF and the Fulton index (r = -0.82). The Fulton index also had a strong correlation with the RVSP (r = 0.79). The Pearson correlation coefficient between the RVEF and the RVSP was -0.81, meaning that the higher the systolic pressure in the right ventricle, the lower the ejection fraction value. Heart rate was significantly correlated to the other three variables studied, although with relatively low correlation. Conclusion: The correlations obtained in this study indicate that the parameters evaluated in the research related to experimental pulmonary hypertension correlate adequately and that the measurements that are currently made are adequate and consistent with each other, that is, they have good predictive capacity.

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