scholarly journals Synthesis, Characterization and Antimicrobial Activity of Ni(II), Zn(II), and Cd(II) Complexes of 3/4-Bromo-Benzoic Acid (Phenyl-Pyridine-2-yl-Methylene)-Hydrazide Ligand

2020 ◽  
Vol 9 (4) ◽  
pp. 1529-1537
Keyword(s):  
Antimicrobial Activity ◽  
Benzoic Acid ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Metal Ion ◽  
Trichophyton Rubrum ◽  
Salmonella Typhi ◽  
Spectral Studies ◽  
Mass Analysis ◽  
Uv Visible

New transition metal complexes [Ni(L)2], [Zn(L)Cl], [Zn(L)2] and [Cd(L)2] were synthesized from 3-bromo-benzoic acid (phenyl-pyridin-2-yl-methylene)-hydrazide (3Bbpph) and 4-bromo-benzoic acid (phenyl-pyridin-2-yl-methylene)-hydrazide (4Bbpph) ligands and were characterized by different physicochemical and spectral studies - IR, elemental, UV Visible, 1H NMR spectra and mass analysis. The data revealed the presence of tetra-coordinate [Zn (L)Cl], whereas [Ni(L)2], [Zn(L)2], and [Cd(L)2] complexes consist of metal ion coordinated with two molecules of ligand to form octahedral geometry. The ligands act as monobasic, tridentate, and coordinated through enolate-O, azomethine-N, and pyridyl-N atoms. The antimicrobial activity of the ligands and metal complexes was investigated against Staphylococcus Aureus, Streptococcus Pyogenes, Escherichia coli, Salmonella typhi, Candida Albicans and Trichophyton Rubrum which revealed that the metal complexes exhibit greater activity than the parent ligands.

scholarly journals Synthesis, Characterizations and Antimicrobial Activity of Metal Complexes of 2-(2-Furanylmethylaminocarbonyl)benzoic Acid

2011 ◽  
Vol 8 (1) ◽  
pp. 443-448 ◽  
Author(s):  
R. H. Patel ◽  
B. L. Hiran
Keyword(s):  
Antimicrobial Activity ◽  
Antifungal Activity ◽  
Transition Metal ◽  
Benzoic Acid ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Elemental Analysis ◽  
Magnetic Moments ◽  
Thermal Studies ◽  
Spectral Studies

The ligand, 2-(2-furanylmethylaminocarbonyl)benzoic acid (FMBA) and it’s transition metal complexes have been synthesized and characterized by elemental analysis, spectral studies, magnetic moments and thermal studies. The antifungal activity of all the samples was monitored against common fungi.

scholarly journals Synthesis, Characterization and Biological Activity of Ni(II), Cu(II) and Fe(III) Complexes Derived from N2,N6-bis(5-Mercapto-1,3,4-thiadiazol-2-yl)pyridine-2,6-dicarboxamide

2020 ◽  
Vol 32 (7) ◽  
pp. 1691-1696
Author(s):  
Anuroop Kumar ◽  
Netra Pal Singh ◽  
Uma Agrawal ◽  
Kaushal Kumar
Keyword(s):  
Antimicrobial Activity ◽  
Metal Complexes ◽  
Metal Ion ◽  
Inhibitory Concentration ◽  
Inhibition Zone ◽  
Molar Conductance ◽  
Minimal Bactericidal Concentration ◽  
Spectroscopic Techniques ◽  
Uv Visible ◽  
Bacteria And Fungi

Novel metal complexes of the type [M(L)X] (where M= Cu(II), Ni(II) and Fe(III), L = N2,N6-bis(5-mercapto-1,3,4-thiadiazol-2-yl)pyridine-2,6-dicarboxamide, X= Cl−, CH3COO−) were synthesized by the reaction of pyridine-2,6-dicarboxylic acid and 2-amino-5-mercepto-1,3,4-thiadiazole. The synthesized ligand was reacted in THF with metal salts (Cu, Ni and Fe) to form complexes. Deprotonated ligand shows tridentate nature and coordinate to metal ion to form pincer cavity. In all, complexes metals were surrounded by three nitrogen atom and other site coordinated by other groups (chloride, acetate). All the synthesized complexes were characterized by spectroscopic techniques like UV-visible, 13C NMR and 1HNMR, IR spectroscopy, DSC, elemental analysis and molar conductance measurements. The ligand and its metal complexes were tested for antimicrobial activity against bacterial and fungal strains by determining inhibition zone, minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC). The complexes showed moderate antimicrobial activity and antifungal activity when tested against bacteria and fungi

scholarly journals Synthesis, Characterization and Antimicrobial Activity of Methylquinolino[3,2-b][1,5]benzodiazepine and Methylquinolino[3,2-b][1,5]benzoxazepine and its Various Metal Complexes

2007 ◽  
Vol 4 (1) ◽  
pp. 32-38 ◽  
Author(s):  
B. Basavaraju ◽  
H. S. Bhojya Naik ◽  
M. C. Prabhakara
Keyword(s):  
Antimicrobial Activity ◽  
Metal Complexes ◽  
Antimicrobial Agents ◽  
Spectral Studies ◽  
Antibacterial And Antifungal Activity ◽  
H Nmr ◽  
Uv Visible ◽  
Bacteria And Fungi ◽  
Antibacterial And Antifungal ◽  
Metal Ligand

2-Chloro-6-methylquinoline-3-carbaldehyde was condensed witho-Phenylenediammine and 2-aminophenol in presence of potassium iodide. The resulting Methylquinolino[3,2-b][1,5]benzodiazepine (MQBD) and Methylquinolino[3,2-b][1,5]benzoxazepine(MQBO) were characterized by elemental analysis and spectral studies. The metal chelatesvizPd(II), Rh(III) and Ru(III) of ligands were prepared and characterized by metal-ligand (M:L) ratio, UV-Visible, IR,1H NMR spectroscopes and magnetic properties. The antibacterial and antifungal activity of MQBD, MQBO and its metal complexes were screened against various bacteria and fungi. The results show that all these samples are good antimicrobial agents.

scholarly journals Synthesis, Characterization, Biological Activity and DNA Binding Studies of Metal Complexes with 4-Aminoantipyrine Schiff Base Ligand

2012 ◽  
Vol 9 (1) ◽  
pp. 389-400 ◽  
Author(s):  
B. Anupama ◽  
M. Padmaja ◽  
C. Gyana Kumari
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Schiff Base Ligand ◽  
Metal Ion ◽  
Spectral Studies ◽  
Significant Activity ◽  
Central Metal ◽  
Binding Studies

A new series of transition metal complexes of Cu(II),Ni(II),Co(II), Zn(II) and VO(IV) have been synthesized from the Schiff base ligand (L) derived from 4-amino antipyrine and 5- bromo salicylaldehyde. The structural features of Schiff base and metal complexes were determined from their elemental analyses, thermogravimetric studies, magneticsusceptibility, molar conductivity, ESI-Mass, IR, UV-VIS,1H NMR and ESR spectral studies. The data show that the complexes have composition of ML2type. The UV-VIS, magnetic susceptibility and ESR spectral data suggest an octahedral geometry around the central metal ion. Biological screening of the complexes reveals that the Schiff base transition metal complexes show significant activity against microorganisms. Binding of Co(II) complex with calf thymus DNA (CT DNA) was studied by spectral methods.

scholarly journals Synthesis Characterization and Antimicrobial Activity of Metal Chelates of 1, 7-Di (2-hydroxyphenyl) 1, 7 di (N-methyl) aza-1, 3, 5 heptarine-3-ol hydrochloride

2010 ◽  
Vol 7 (3) ◽  
pp. 775-778
Author(s):  
Nalin P. Patani ◽  
M. V. Hathi
Keyword(s):  
Antimicrobial Activity ◽  
Magnetic Properties ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Elemental Analysis ◽  
Schiff Base Complexes ◽  
Spectral Studies ◽  
Ir Reflectance ◽  
Amino Phenol ◽  
Metal Ligand

The Schiff base complexes derived from 2-furancarboxaldehyde and N-methyl-2-amino phenol have been prepared and characterized using several physical techniques, like elemental analysis, thermogravimetric analysis, magnetic moment measurements, infrared and resonance spectra.N-Methyl-2-amino phenol was condensed stoichiometrically with 2-furancarboxaldehyde in presence of methanol. The resulting 1,7-di(2-hydroxyphenyl) 1,7 di(N-methyl) aza-1,3,5 heptarine-3-ol hydrochloride was characterized by elemental analysis and spectral studies. The transition metal complexes of Cu2+, Zn2+, Ni2+, Co2+and Mn2+of the synthesized complexes were prepared. Metal ligand (M:L) ratio, IR, reflectance spectral studies, magnetic properties and antimicrobial activity of the synthesized complexes and its metal complexes were carried out.

scholarly journals Bioactive Metal Complexes of Schiff Base Derived from 2,3-Dioxobutane, Ethane-1,2-diamine and 4-Chloro-2-formylphenol: Spectral Studies and in vitro Antimicrobial Activity

2021 ◽  
Vol 33 (12) ◽  
pp. 3063-3069
Author(s):  
Abhay Nanda Srivastva ◽  
Sayanwita Panja ◽  
Netra Pal Singh ◽  
Chandra Kiran Shriwastaw
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Magnetic Moment ◽  
Metal Ion ◽  
Molar Conductance ◽  
Spectral Studies ◽  
Coordination Behaviour ◽  
Uv Visible ◽  
Iron Chromium

A novel series of trivalent coordination complexes was synthesized by the reaction between a chloride/ acetate salt of iron, chromium, cobalt or manganese ions and NNNNOO type persuasive Schiff base ligand synthesized from 2,3-dioxobutane, ethane-1,2-diamine and 4-chloro-2-formylphenol. Synthesized compounds were characterized by using elemental analysis, molar conductance, magnetic moment, IR, UV-visible, 1H NMR, 13C NMR and ESI-MS spectral analyses. IR and NMR spectra favoured hexadentate coordination behaviour of ligand. Electronic spectra and magnetic moment data reveal Oh geometry with distortion around the metal ion in complexes. The molar conductance values show 1:1 electrolytic nature of complexes. Biological potentiality of the ligand and its metal complexes were tested in vitro against two bacterial and two fungal strains; Bacillus subtilis, Escherichia coli and Aspirgillus niger, Aspirgillus flavus, respectively.

scholarly journals Designing, synthesis and spectral characterization of Schiff base transition metal complexes: DNA cleavage and antimicrobial activity studies

2008 ◽  
Vol 73 (11) ◽  
pp. 1063-1071 ◽  
Author(s):  
N. Raman ◽  
Syed Ali ◽  
Dhaveethu Raja
Keyword(s):  
Magnetic Susceptibility ◽  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Spectral Data ◽  
Transition Metal Complexes ◽  
Metal Ion ◽  
Spectral Studies ◽  
Central Metal ◽  
Elemental Analyses

A new series of transition metal complexes of Cu(II), Ni(II), Co(II) and Zn(II) have been designed and synthesized using a Schiff base (L) derived from 4-aminoantipyrine, benzaldehyde and o-phenylenediamine. The structural features were derived from their elemental analyses, magnetic susceptibility and molar conductivity, as well as from mass, IR, UV-Vis, 1H-NMR and ESR spectral studies. The FAB mass spectral data and elemental analyses showed that the complexes had a composition of the ML type. The UV-Vis and ESR spectral data of the complexes suggested a square-planar geometry around the central metal ion. The magnetic susceptibility values of the complexes indicated that they were monomeric in nature. Antimicrobial screening tests were also performed against four bacteria, viz. Salmonella typhi, Staphylococcus aureus, Escherichia coli, and Bacillus subtilis and three fungi, viz. Aspergillus niger, Aspergillus flavus and Rhizoctonia bataicola. These data gave good results in the presence of metal ion in the ligand system. The nuclease activity of the above metal complexes shows that only the copper complex cleaves CT DNA in the presence of an oxidant.

scholarly journals Synthesis, Spectral Characterization, and Biological Evaluation of Transition Metal Complexes of Bidentate N, O Donor Schiff Bases

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Sajjad Hussain Sumrra ◽  
Muhammad Ibrahim ◽  
Sabahat Ambreen ◽  
Muhammad Imran ◽  
Muhammad Danish ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Metal Complexes ◽  
Schiff Bases ◽  
Transition Metal Complexes ◽  
Metal Ion ◽  
Analytical Data ◽  
Biological Evaluation ◽  
Equimolar Ratio ◽  
Donor Type ◽  
Good Agreement

New series of three bidentate N, O donor type Schiff bases(L1)–(L3)were prepared by using ethylene-1,2-diamine with 5-methyl furfural, 2-anisaldehyde, and 2-hydroxybenzaldehyde in an equimolar ratio. These ligands were further complexed with Co(II), Cu(II), Ni(II), and Zn(II) metals to produce their new metal complexes having an octahedral geometry. These compounds were characterized on the basis of their physical, spectral, and analytical data. Elemental analysis and spectral data of the uncomplexed ligands and their metal(II) complexes were found to be in good agreement with their structures, indicating high purity of all the compounds. All ligands and their metal complexes were screened for antimicrobial activity. The results of antimicrobial activity indicated that metal complexes have significantly higher activity than corresponding ligands. This higher activity might be due to chelation process which reduces the polarity of metal ion by coordinating with ligands.

scholarly journals Synthesis and Structural Properties of Copper(II), Nickel(II) and Cobalt(II) Complexes with 2,4-Furyliminobenzylacetophenone

2012 ◽  
Vol 2012 ◽  
pp. 1-6
Author(s):  
Jagvir Singh ◽  
Prashant Singh
Keyword(s):  
Antimicrobial Activity ◽  
Magnetic Susceptibility ◽  
Metal Complexes ◽  
Metal Ion ◽  
Fungal Species ◽  
Octahedral Geometry ◽  
Visible Spectroscopy ◽  
Uv Visible ◽  
Chloride Salts ◽  
C Nmr

The new Schiff base ligand (FIAS) 2,4-furyliminobenzylacetophenone has been synthesized with 4-aminoacetophenone and furane-2-carboxaldehyde by condensation in ethanol. Metal complexes of the ligand were prepared with chloride salts of copper(II), nickel(II) and cobalt(II) in ethanol. The ligand and its metal complexes have been characterized by microanalysis, magnetic susceptibility, FTIR, 1H and 13C NMR, mass spectrum, and UV-visible spectroscopy techniques. From these findings, it is suggested that metal ion coordinate by imines nitrogen and carboxylic oxygen atoms of FIAS to form octahedral geometry. All the newly compounds were tested antimicrobial activity against bacterial and fungal species.

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