scholarly journals A Comparative Study of Effects of Different Grades of Maternal Established Diabetes Mellitus on Placental and Neonatal Weight

1970 ◽  
Vol 9 (1) ◽  
pp. 53-58 ◽  
Author(s):  
AHMM Mawla Chowdhury ◽  
Khondker Manzare Shamim ◽  
Roxana Ferdousi ◽  
Janah Ara Begum ◽  
Laila Anjuman Banu
Keyword(s):  
Diabetes Mellitus ◽  
Glucose Level ◽  
Plasma Glucose ◽  
Plasma Glucose Level ◽  
Mean Value ◽  
Placental Weight ◽  
Control Mother ◽  
The Mean ◽  
The Difference ◽  
Venous Plasma

Context: Aiming the effects of severity of diabetes mellitus on human placenta and the neonatal outcome, a quantitative study at the macroscopic level was designed. Material and Methods: Sixty post caesarean section human placentae were studied of which thirty were from mothers having established diabetes mellitus considered as EDM and thirty were from control mother having no diabetes mellitus. EDM mothers were treated with insulin. Venous plasma glucose level (fasting and 2 hours after breakfast) of the EDM mothers in 2nd and 3rd trimester were recorded and the mean of the values were calculated. Results: The values ranged from 5.93 to 10.10mmol/L and the mean was 7.28±0.99 m mol/L. The mothers having EDM were grouped according to the mean venous plasma glucose level. The mothers having a mean level up to 8.3 m mol/L and those having a level above 8.3 m mol/L were designated as the Low-EDM and High- EDM group respectively. Placental weight in Control, Low-EDM and High-EDM groups were 414.93±95.41, 403.83±68.53 gm and 446.33± 82.23gm respectively. The value showed lower mean value in Low-EDM group. The difference did not reach a significant level. The neonatal weight in Control, Low-EDM and High-EDM groups were 2958.33±537gm, 2997.91±540 gm and 3300.00±379 gm respectively. The weight of the neonates did show a tendency towards being heavier in EDM groups but did not reach the significant level. There was a significant positive correlation between the neonatal weight and placental weight in control and Low-EDM group. Key words: Established diabetes mellitus; Placenta; Neonates DOI: http://dx.doi.org/ 10.3329/bja.v9i1.8150 Bangladesh Journal of Anatomy January 2011, Vol. 9 No. 1 pp 53-58

scholarly journals Effects of Insulin treated Established Diabetes Mellitus (EDM) on the Volume of Placental Parenchyma and Weight of the Neonate

1970 ◽  
Vol 7 (1) ◽  
pp. 45-48
Author(s):  
AHMM Mawla Chowdhury ◽  
Selina Anwar ◽  
Meherunnessa Begum ◽  
K Nahid Eva ◽  
Fahmida Shahnaz
Keyword(s):  
Diabetes Mellitus ◽  
Plasma Glucose Level ◽  
Significant Positive Correlation ◽  
Well Being ◽  
Mean Value ◽  
Third Trimester ◽  
Control Mother ◽  
The Mean ◽  
Diabetic Mothers ◽  
Venous Plasma

Taking in mind the effects of diabetes mellitus of varying severity on human placenta and their implication on the well being of the fetus, a quantitative study at the macroscopic level was designed. Sixty post caesarean section human placentas were studied of which thirty were from mothers having insulin treated established diabetes mellitus (EDM) considered as EDM group and thirty were from control mother having no diabetes mellitus. The venous plasma glucose level (fasting and two hours after breakfast) of the diabetic mothers in second and third trimester were recorded and the mean of the values were calculated. The value ranged from 5.93 to 10.10 and the mean was 7.28±0.90. The two groups did not differ significantly from each other with age, weight, height, or parity of the mother or in gestational age. Parenchymal volume in control and EDM group were 300.14±75.43 and 309.25±61.64 respectively. The value showed higher mean value in EDM group. The differences did not reach a significant level. The neonatal weight in control and EDM group were 2.95±0.53 and 3.05±0.52 respectively. The neonate did show a tendency towards being heavier in EDM group, but no reached the significant level. There was a significant positive correlation between the neonatal weight and the parenchymal volume in control and EDM groups. Key words: Established Diabetes Mellitus, Placenta, Parenchyma, Neonates.   doi: 10.3329/bja.v7i1.3025 Bangladesh Journal of Anatomy January 2009, Vol. 7 No. 1 pp. 45-48

scholarly journals TO STUDY THE EFFECT OF YOGA ON BLOOD SUGAR PROFILE IN DIABETICS TYPE-2 PATIENTS

2019 ◽  
Vol 3 (7) ◽  
Author(s):  
Dr. B S Gupta ◽  
Dr. Yogesh Singh
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Mean Value ◽  
T Test ◽  
Diabetic Patients ◽  
The Mean ◽  
The Difference

Background: Diabetes mellitus is a syndrome complex characterized by impaired carbohydrate, protein and fat metabolism. Methods: Prospective study was conducted on 100 type 2 diabetes mellitus patients and 100 normal healthy persons. Cases were recruited from a yoga centre. Control subjects were selected from diabetic patients attending hospital. Alcoholic or smoker subjects were excluded. Results: The mean value of blood glucose level of subjects was 136.4±9.42 mg/dl and that of controls was 183.2±9.16 mg/dl.  The difference between the mean value of fasting blood glucose level determined by unpaired  ‘t’ test was statistically highly significant (p=<0001). The mean value of blood glucose level of subjects was 6.32±1.35 % and that of controls was 7.46±1.41%.  The difference between the mean value of HB1Ac level determined by unpaired  ‘t’ test was statistically highly significant (p=<0001). Conclusion: Yoga can be used as an alternate therapy to reduce the blood glucose level along with the drug therapy. Keywords: Yoga, Diabetics, Drugs.

scholarly journals Prevalence of gestational diabetes mellitus and its feto-maternal outcome in Kamla Nehru state hospital for mother and child, IGMC, Shimla, India

2018 ◽  
Vol 7 (11) ◽  
pp. 4662
Author(s):  
Aleeza Pal ◽  
Bishan Dhiman ◽  
Rita Mittal ◽  
Bhaskar J. Paul
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
State Hospital ◽  
Glucose Level ◽  
Plasma Glucose ◽  
Plasma Glucose Level ◽  
Maternal Outcome ◽  
Vaginal Candidiasis ◽  
Mother And Child

Background: Gestational Diabetes Mellitus (GDM) is defined as carbohydrate intolerance of variable severity with the onset or first recognition during pregnancy. It is a disease entity that adversely affects maternal as well as fetal outcome. DIPSI guideline having suggested one-time plasma glucose level has emerged as a simple, practical and cheap method to detect GDM. This study was done to evaluate the prevalence of gestational diabetes using Diabetes in Pregnancy Study Group India (DIPSI) criteria and further assess its feto maternal outcome in Kamla Nehru State Hospital for Mother and Child, IGMC, Shimla.Methods: This study was conducted in 500 patients between 24 and 28 weeks of gestation, attending the antenatal OPD. These patients were given 75g oral glucose irrespective of last meal and their plasma glucose was estimated at 2h. Patients with plasma glucose ≥140mg/dl were diagnosed as GDM and the rest as control or the non GDM group. The GDM patients were followed up and treated with medical nutrition therapy (MNT) and/or insulin therapy till delivery and maternal and fetal outcomes were then noted.Results: The prevalence of GDM in this study was 6%. Maternal and fetal complications were more in the GDM patients. Vaginal candidiasis and PROM were the common maternal complications, while hypoglycemia and hyperbilirubinemia were common in the fetuses.Conclusions: GDM adversely affects the mother as well as fetus. DIPSI guideline having suggested a single plasma glucose level test has emerged as a practical and economical method to detect GDM.

scholarly journals Body mass index influences the plasma glucose concentration during iatrogenic hypoglycemia in people with type 2 diabetes mellitus: a cross-sectional study

PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e4348 ◽  
Author(s):  
Po Chung Cheng ◽  
Shang Ren Hsu ◽  
Shih Te Tu ◽  
Yun Chung Cheng ◽  
Yu Hsiu Liu
Keyword(s):  
Diabetes Mellitus ◽  
Glucose Level ◽  
Plasma Glucose ◽  
Glucose Concentration ◽  
Multivariate Regression ◽  
Plasma Glucose Level ◽  
Severe Hypoglycemia ◽  
Multivariate Regression Analysis ◽  
Plasma Glucose Concentration

Background Hypoglycemia occurs in an appreciable number of individuals with type 2 diabetes mellitus (T2DM) who are receiving glycemic therapy. Iatrogenic hypoglycemia induces not only complications but also a substantial medical expense. Intervention for relevant risk factors may help avert severe hypoglycemia and enhance quality of life in at-risk individuals. This study investigates the relationship between body mass index (BMI) and plasma glucose concentration during iatrogenic hypoglycemia in people with T2DM. Methods Enrollment criteria were people above 20 years of age, with existing diagnosis of T2DM, a documented plasma glucose level ≤70 mg/dL, and acute cognitive impairment requiring hospitalization. Participants were classified into two groups according to their BMI. Specifically, lower BMI subgroup denotes individuals whose BMI fall within lower half of the study population, and vice versa. Plasma glucose concentration, length of hospital stay, and serum electrolyte level at hospitalization were compared between these BMI subgroups. Moreover, multivariate regression analysis was performed to identify covariates associated with plasma glucose level during iatrogenic hypoglycemia. Results This study enrolled 107 participants for whom 54 were assigned to a higher BMI subgroup and the remainder to a lower BMI subgroup. People with lower BMI harbored substantially reduced plasma glucose concentration during iatrogenic hypoglycemia compared to those with higher BMI (30.1 ± 9.6 mg/dL vs. 38.4 ± 12.3 mg/dL, P < 0.001). Nonetheless, the length of stay (6.2 ± 4.6 days vs. 5.7 ± 4.0 days, P = 0.77) and serum potassium level (3.7 ± 0.9 meq/L vs. 3.9 ± 0.8 meq/L, P = 0.14) were comparable between subgroups. Multivariate regression analysis identified BMI as a determinant of plasma glucose concentration in diabetic individuals with iatrogenic hypoglycemia (β coefficient: 0.72, P = 0.008). Discussion In individuals with T2DM who experience severe iatrogenic hypoglycemia, BMI influences the plasma glucose level at hospitalization. People with lower BMI harbored appreciably reduced plasma glucose concentration relative to their higher BMI counterparts. In lower weight people, therefore, appropriate dosing of antidiabetic medications, frequent self-monitoring of blood glucose level and adequate nutritional support may help avert more severe hypoglycemia. Overall, BMI potentially influences the severity of iatrogenic hypoglycemia in people with T2DM.

scholarly journals The Effect of Tempe Dietary Intake on Plasma Glucose Level in Elderly Patients with Type 2 Diabetes Mellitus

2017 ◽  
Vol 1 (6) ◽  
Author(s):  
Grace Puspasari ◽  
Drupadi Dillon ◽  
Budiman Budiman
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Treatment Group ◽  
Glucose Level ◽  
Plasma Glucose ◽  
Plasma Glucose Level ◽  
Daily Intake ◽  
Control Group

The aim of the study was to investigate  the effect of daily intake of 100 grams tempe for four weeks on plasma glucose level in elderly patients with type 2 diabetes mellitus. This study was a parallel randomized clinical trial. Subjects were 30 diabetic elderly living in four nursing homes in Jakarta. In the study subjects were assigned to two groups using block randomization. All subjects had to take diabetic regiment with calorie and macronutrient following diabetic recommendation diet. The treatment group (n=16) received tempe, while control group (n=14) received legumes other than tempe. Fasting plasma glucose level (FPG) was assessed before and after intervention. Unpaired t test and Mann Whitney were used to analyzed data with the 5% significance level. There were 27 subjects completed the study: 15 of treatment group and 12 of control group. Both group were comparable in age, gender, BMI, calorie and macronutrient intake before treatment. Fat, fiber, and isoflavone intake were significantly higher in treatment group compare to control group. Decrease in FPG after intervention were observed but were statisticaly insignificant. In conclusion daily intake of 100 grams tempe for four weeks did not decrease FPG.  Keywords: elderly, plasma glucose level, tempe, type 2 diabetes

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