scholarly journals IMMUNE RESPONSE CAPABILITY OF `SHUVRA’ CHICKEN

2013 ◽  
Vol 10 (1-2) ◽  
pp. 1-7
Author(s):  
M. S. Sabrin ◽  
S. Saha ◽  
M. M. Amin
Keyword(s):  
Immune Response ◽  
Newcastle Disease Virus ◽  
Newcastle Disease ◽  
Humoral Immune Response ◽  
Passive Haemagglutination ◽  
Fowl Cholera ◽  
Humoral Immune ◽  
Unvaccinated Control ◽  
And Control ◽  
Observation Period

The study was carried out to determine the humoral immune response to Newcastle Disease Virus (NDV) and Bangladesh Agricultural University Fowl cholera (BAUFC) vaccines in Shuvra chicken, a newly develop chicken strain by BLRI (Bangladesh Livestock Research Institute). Ten Shuvra chickens were vaccinated with Baby Chick Ranikhet Disease Vaccine (BCRDV) at day 7 through intra ocular route (i/o) and with Ranikhet Disease Vaccine (RDV) at day 35 through intramuscular (i/m) route. Vaccine induced serum Haemagglunination Inhibition (HI) antibodies were measured by HI test. Two weeks after final immunization all vaccinated and control Shuvra chickens were challenged with virulent field isolates of  NDV where all the vaccinated birds survived without showing any typical signs of NDV during the period of ten days observation period and all the control chickens died.  Another 10 Shuvra were vaccinated twice with BAUFC vaccine through intramuscular route at day 42 and 70, and 10 Shuvra chickens were kept as unvaccinated control. This vaccine also induced significantly higher level of antibody titre as determined by Passive Haemagglutination (PHA) test. Vaccinated chickens showed significantly higher survival (80%) following challenge with virulent fowl cholera isolate and all the control birds died within 10 days of observation period. DOI: http://dx.doi.org/10.3329/bjvm.v10i1-2.15639Bangl. J. Vet. Med. (2012). 10 (1&2): 1-7

Immunomodulatory Potential of Microencapsulated Multispecies Probiotic Consortium in Newcastle Disease Virus Vaccinated Chicken

2019 ◽  
Author(s):  
G. Radhika ◽  
S. Subriya ◽  
K. Divya Manjari ◽  
M. Parthiban ◽  
N. Pazhanivel ◽  
...  
Keyword(s):  
Immune Response ◽  
Newcastle Disease ◽  
Immune Modulation ◽  
Cell Receptor ◽  
Probiotic Supplementation ◽  
Humoral Immune ◽  
Th2 Cytokine ◽  
Cell Mediated Immune Response ◽  
And Control ◽  
Immunomodulatory Potential

A study was conducted to investigate the effect of microencapsulated probiotic consortium containing Lactobacillus plantarum, Enterococcus faecium, Enterococcus hirae, Pediococcus acidilactici and Weissella paramesenteroides on immune modulation in Newcastle Disease vaccinated chicken. Humoral immune response was assessed by ELISA. Th1, Th2 cytokine response and cell mediated immune response were assessed by using Real time PCR and flow cytometry respectively. Results indicated significantly (p less than 0.01) higher antibody titer and also higher IL-2, IL-12, IL-4 and IL-10 cytokine expression in NDV vaccinated multispecies probiotic fed group compared to commercial probiotic fed and control groups. It was also observed that higher proportions of Bu1A (B cell receptor) and CD3 (T cell receptor) positive cells in chicken fed with multispecies probiotic supplementation. Hence, it is concluded that multispecies probiotic played an important role in augmenting humoral and cell mediated immune response against NDV.

scholarly journals EVALUATION OF MATERNALLY DERIVED ANTIBODIES AGAINST NEWCASTLE DISEASE VIRUS AND ITS EFFECT ON VACCINATION IN BROILER CHICKS

2010 ◽  
Vol 7 (2) ◽  
pp. 296-302 ◽  
Author(s):  
MA Jalil ◽  
MA Samad ◽  
MT Islam
Keyword(s):  
Immune Response ◽  
Newcastle Disease ◽  
Humoral Immune Response ◽  
Broiler Chickens ◽  
Primary Vaccination ◽  
Challenge Infection ◽  
Broiler Chicks ◽  
Humoral Immune ◽  
Different Ages ◽  
Group B

The study was conducted to determine the persistence of maternally derived antibody (MDA) and its effects on protection against NDV in broiler chickens and to investigate the status of humoral immune response following vaccination with BCRDV® (F-strain, lentogenic) at different ages of broiler chickens during the period from August to October,  2008. A total of 90 day-old broiler chicks of Cobb 500 strain with the history of vaccination of parent stock against Newcastle disease (ND) was divided into three groups (A, B and C). Birds of group A (n = 35) were used for the study of protection ability of MDA against NDV, the birds of group B (n = 45) were used for the measurement of humoral immune response in chickens following vaccination at different ages and birds of group C (n = 10) were used for the determination of persistence of maternally derived antibody. The level of antibody titre against NDV was determined by HI test. The protective potentiality of MDA and vaccine was determined by the rate of survivability of the chickens following challenge infection. It was observed that the MDA titre in day-old chicks was higher and gradually declined at minimal level at day 28. The MDA titre of 128 or above protected the birds following challenge infection with virulent NDV. There were significant decrease in HI titres of chickens which were vaccinated once at day 1 and day 7, and could not withstand challenge infection with virulent NDV. Single vaccination with BCRDV® at day 14 triggered the production of antibody but could not provide complete protection to the birds. The birds which were boosted with the same vaccine 7 days and 21 days after primary vaccination produced better immune response. However, the birds which were vaccinated primarily at day 1 and boosted at day 7 could not withstand the challenge completely. Of the other regimens of twice vaccination, primary vaccination at day 7 and booster dosing at day 28 was found to be the best in terms of immune response and protection potentiality. Therefore, it may be concluded that (a) The MDA titre level of 128 or above is sufficient to protect broilers against challenge with virulent NDV,( b) Primary vaccination at day 7 followed by a booster dosing at day 28 may be followed for better immune response and protection against ND in broilers.DOI: 10.3329/bjvm.v7i2.5995Bangl. J. Vet. Med. (2009). 7(2) : 296 – 302

scholarly journals Immune response and protective potential following vaccination against Newcastle disease virus and fowl cholera in Naked neck chickens

2013 ◽  
Vol 29 (2) ◽  
pp. 49-55
Author(s):  
MS Sabrin ◽  
S Saha ◽  
MM Amin ◽  
MG Hossain
Keyword(s):  
Immune Responses ◽  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Field Isolate ◽  
Haemagglutination Inhibition ◽  
Naked Neck ◽  
Fowl Cholera ◽  
Humoral Immune ◽  
Humoral Immune Responses

Humoral immune responses to Newcastle Disease Virus (NDV) and Bangladesh Agricultural University (BAU) Fowl cholera (BAUFC) vaccines were evaluated in naked neck chickens (NNC). Ten birds were vaccinated with Baby Chick Ranikhet Disease Virus (BCRDV) at Day 7 through intra-ocular route and with Ranikhet Disease Virus (RDV) at day 35 of age through intramuscular route. Serum antibodies were measured by Haemagglutination Inhibition test. Two weeks after final immunization all birds were challenged with virulent field isolate of NDV where all vaccinated birds survived without illness during ten days, and all ten control birds died. Ten birds were vaccinated with BAUFC vaccine at Day 42 and 70 according to the Manufacturer’s instruction, which induced detectable levels of antibody titre as determined by Passive Haemagglutination Assay (PHA) test. Eight vaccinated birds survived following challenge with virulent fowl cholera isolate two weeks after final vaccination and all ten control birds died. DOI: http://dx.doi.org/10.3329/bvet.v29i2.14342 Bangl. vet. 2012. Vol. 29, No. 2, 49-55

HUMORAL IMMUNE RESPONSE TO FOWL CHOLERA VACCINE IN DIFFERENT BREEDS OF COMMERCIAL BIRDS

2013 ◽  
Vol 9 (2) ◽  
pp. 127-131
Author(s):  
MS Parvin ◽  
MP Siddique ◽  
MT Islam
Keyword(s):  
Immune Response ◽  
Rhode Island ◽  
Antibody Titre ◽  
Humoral Immune Response ◽  
Serum Antibody ◽  
Booster Vaccination ◽  
Cholera Vaccine ◽  
Fowl Cholera ◽  
Humoral Immune ◽  
Antibody Titres

Fowl cholera is a highly contagious and economically important disease of poultry worldwide. Control of fowl cholera depends mainly on vaccination throughout the world including Bangladesh. Therefore, the objective of the study was to determine the antibody titre following vaccination with fowl cholera vaccine in different breeds of commercial birds including Aseel and its F1 crosses. The study was conducted at Bangladesh Agricultural University Poultry Farm during the period from March to December 2011. A total of 37 birds of four types of breeds (Synthetic - 10, White Rock - 10, Aseel - 7 and Aseel×Rhode Island Red - 10) of both sex and 17 weeks old were used in this trial. Primary and booster vaccination were done in all the birds of four groups with fowl cholera vaccine (BAU-FCV) @ 0.5 ml/bird IM at 20 weeks and 26 weeks of age, respectively. Blood samples were collected at different occasions of vaccination. The immune responses (serum antibody titre) were determined by using passive haemagglutination assay (PHA). All the four groups of vaccinated birds induced significantly higher humoral immune response after primary and booster vaccination. However, no significant differences were observed in antibody titres between breeds on different occasions of vaccination. Of the four groups, antibody titres were slightly higher in breeds of Aseel×RIR and White Rock birds than other two breeds. It appears from the study that breed variation has no significant effect on immune response to fowl cholera vaccine.DOI: http://dx.doi.org/10.3329/bjvm.v9i2.13453

scholarly journals Radiation leukemia in C57BL/6 mice. I. Lack of serological evidence for the role of endogenous ecotropic viruses in pathogenesis.

1976 ◽  
Vol 144 (6) ◽  
pp. 1391-1405 ◽  
Author(s):  
J N Ihle ◽  
R McEwan ◽  
K Bengali
Keyword(s):  
Bone Marrow ◽  
Immune Response ◽  
Humoral Immune Response ◽  
Experimental Conditions ◽  
Humoral Immune ◽  
Apparent Correlation ◽  
Radiation Induced ◽  
Leukemia Viruses ◽  
And Control

The humoral immune response against endogenous ecotropic murine leukemia viruses (MuLV) was examined in irradiated and control C57BL/6 mice. Control mice developed antibodies against MuLV slowly throughout life. In contrast, within 2-3 mo after irradiation 90% of irradiated C57BL/6 mice had developed detectable antibodies against MuLV. The characteristics of this immune response, however, were identical in control and irradiated mice in terms of peak titers, specificity for endogenous ecotropic MuLV, and reactivity against the ecotropic viruses' glycoprotein (gp71). Moreover, the rate of appearance of antibodies against MuLV in irradiated mice and the peak titers were generally not affected by age at irradiation, dose of irradiation (two, three, or four treatments of 175 R), or bone marrow reconstitution. Although the ability of irradiation to accelerate the appearance of antibody in a population of C57BL/6 mice suggested activation of endogenous ecotropic MuLV, there was no apparent correlation between the appearance of this immune response or its persistence and the development of lymphoma. Thus, the incidence of lymphoma was comparable in mice that: (a) developed no immune response; (b) developed an immune response only transiently after irradiation; or (c) developed an immune response which persisted until death from lymphoma. Moreover, experimental conditions that alter the ability of irradiation to induce leukemia, such as age, dose, or bone marrow reconstitution did so without significantly altering either the rate of appearance of a humoral immune response to MuLV or its peak titers. The results, therefore, fail to demonstrate any seroepidemological relationship between endogenous ecotropic MuLV and radiation-induced leukemia.

Humoral Immune Response to Newcastle Disease Vaccine (Lastoa Strain) in Broilers

2006 ◽  
Vol 5 (5) ◽  
pp. 411-414 ◽  
Author(s):  
Muhammad Shuaib . ◽  
Hamayun Khan . ◽  
Sajid-ur-Rehman . ◽  
Muhammad Ashfaque .
Keyword(s):  
Immune Response ◽  
Newcastle Disease ◽  
Humoral Immune Response ◽  
Humoral Immune ◽  
Newcastle Disease Vaccine
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