scholarly journals Association of GRACE Risk Score with Angiographic Severity of Coronary Artery Disease in patients with ST Elevation Myocardial Infarction

2015 ◽  
Vol 8 (1) ◽  
pp. 30-34 ◽  
Author(s):  
Tapash Saha ◽  
Md Khalequzzaman ◽  
Md Abdul Kader Akanda ◽  
Simu Saha ◽  
Asif Zaman Tushar ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Risk Score ◽  
Risk Group ◽  
Gensini Score ◽  
Grace Risk Score ◽  
St Elevation ◽  
Artery Disease ◽  
Grace Score

Background: Clinical guidelines recommend that optimal management of acute coronary syndrome should include patient risk stratification. Predicting the anatomical extension of coronary artery disease is also potentially useful for clinical decision. The objective of our study is to determine whether the GRACE risk score correlates with the angiographic extent and severity of coronary artery disease in patients with ST elevation myocardial infarction.Methodology: 50 patients diagnosed with Acute Myocardial Infarction were included as sample by purposive sampling method. GRACE risk score for each patient was calculated and the patients were divided into groups according to the GRACE risk score: low risk (<108); intermediate risk (109-140). The severity of the coronary artery disease was assessed by vessel score and Gensini score. Relation between Grace score and Gensini score was evaluated.Results: Mean GRACE score of study population was 128.3±22.7. Mean Gensini score was 23.88±17. Mean Gensini score were 15.47±10.4, 27.75±9.26 and 31.52±16.91 in low GRACE risk group, intermediate group and high risk group respectively and the difference of mean Gensini score was statistically significant (p=0.006). In our study correlation co-efficient between GRACE risk score and Gensini score was r=0.17 (p=0.04). Multiple regression analysis showed that age more than 50 years (p=0.02), ST segment deviation (p=0.01), smoking (p=0.02), hypertension (p=0.01) were able to independently predict patients with severe CAD.Conclusion: Our study demonstrates that the GRACE risk score carries a significant positive correlation with the coronary artery disease severity in patients with STEMI.Cardiovasc. j. 2015; 8(1): 30-34

scholarly journals The value of the Global Registry of Acute Coronary Events and Gensini scores in predicting long-term outcomes in Vietnamese patients with non-ST-elevation acute coronary syndrome

2021 ◽  
Vol 8 (2) ◽  
pp. 4233-4240
Author(s):  
Sy Van Hoang ◽  
Kha Minh Nguyen ◽  
An Hoang Nguyen ◽  
Khoa Le Anh Huynh ◽  
Hai Phuong Nguyen Tran
Keyword(s):  
Risk Score ◽  
Gensini Score ◽  
Long Term Outcomes ◽  
Coronary Syndrome ◽  
Grace Risk Score ◽  
St Elevation ◽  
Coronary Events ◽  
Artery Disease ◽  
Grace Score

Introduction: Patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) should undergo risk stratification as soon as possible after their presentation. Early risk satisfaction provides good prognosis for patients as well as better decision for reperfusion therapy. The aim of this study is to find a correlation between the Global Registry of Acute Coronary Events (GRACE) risk score and severity of coronay artery disease assessed by Gensini score score and compare the value of GRACE and Gensini scores in predicting the long-term outcomes in patients with NSTE-ACS. Methods: A total of 220 patients with NSTE-ACS who underwent coronary angiography were enrolled in our study. The Gensini score was used to assess the severity of coronary artery disease. According to the GRACE score, the patients were grouped into low, intermediate and high groups. After 30 months of follow-up, 20 patients died. Results: The mean Gensini scores were 11.8 ± 11.5, 27.4 ± 30.9, and 42.9 ± 29.7 in the low, intermediate and high-risk groups, respectively. The GRACE scores and Gensini score had a moderate positive correlation (rho = 0.522, p < 0.001). The survival rates showed a less rapid deterioration from the low to high GRACE groups (P = 0.013) than when classified according to their Gensini tertiles (P = 0.02). Area under the ROC curve was statistically significant for both scores, but area of the GRACE risk score (0.71; 95% Cl = 0.60 - 0.82) was higher than that the Gensini risk score (0.66; 95% Cl = 0.53 – 0.80). Conclusion: Our study revealed that the Gensini score had a positive and significant relationship with the GRACE score in patients with NSTE-ACS. The GRACE score had a more value in predicting long-term outcomes in patients with NSTE-ACS.

Association of Haemoglobin A1c Level with the Severity of Coronary Artery Disease in Non-diabetic Patients with Non-STSegment Elevation Myocardial Infarction

2021 ◽  
Vol 35 (2) ◽  
pp. 134-139
Author(s):  
Md Mamunuzzaman ◽  
Mahboob Ali ◽  
Mir Jamal Uddin ◽  
Shaila Nabi ◽  
Kajal Kumar Karmoker ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Diabetic Patients ◽  
Gensini Score ◽  
Group I ◽  
St Elevation ◽  
Group Ii ◽  
Artery Disease ◽  
Vessel Score

Background: In nondiabetic patients with non-STsegment– elevation myocardial infarction, hyperglycemia may be associated with adverse outcome. Objective: To find out the association between HbA1c levels and the severity of coronary artery disease in non-diabetic patients with non-ST-segment elevation myocardial infarction Methods: This cross sectional analytical study was carried out at the National Institute of Cardiovascular Diseases (NICVD), Dhaka, during the period from July, 2012 to May, 2013. This study was done with an aim to find out the association between the HbA1c level and the angiographic severity of coronary artery disease in patients with non-ST- elevation myocardial infarction without diabetes mellitus. A total of 170 patients with NSTEMI without diabetes mellitus who agreed to undergo coronary angiography were included in the study. Eighty five patients were selected having HbA1c <5.7% (Group I) and 85 patients were selected having HbA1c ranging from 5.7% to 6.4% (Group II). Severity of the Coronary Artery Disease (CAD) was assessed by angiographic vessel score, and Gensini score. Results: The mean age of the studied patients was 51.0±9.0 years ranging from 30 to 80 years and male to female ratio was 4.5:1. The incidence of hypertension and level of RBS were significantly higher in group II than group I. The HbA1c level increased in accordance with the vessel score increment. There was a significant difference of the mean value of HbA1c among the vessel involvement groups. In this study mild CAD (scored”36) was significantly higher in group I and moderate to severe CAD (score>36) was significantly higher in group II according to Gensini score. This study showed a positive correlation between HbA1c and vessel score (r=0.47, p=0.01) and also between HbA1c and Gensini score (r=0.41, p=0.01). Conclusion: Elevated HbA1c levels in non-diabetic non- ST- elevation myocardial infarction patients are associated with the severity of coronary artery disease. Bangladesh Heart Journal 2020; 35(2) : 134-139

scholarly journals Correlation between Myocardial Strain and Angiographic Severity of Coronary Artery Disease in Non-ST-Elevation Myocardial Infarction Patient

2020 ◽  
Vol 5 (03) ◽  
Author(s):  
Md. Al-Amin ◽  
Md. Mashiul Alam ◽  
Tanjima Parvin ◽  
Chaudhury Meshkat Ahmed ◽  
Md. Zainal Abedin ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Longitudinal Strain ◽  
Global Longitudinal Strain ◽  
Myocardial Strain ◽  
St Elevation Myocardial Infarction ◽  
Gensini Score ◽  
St Elevation ◽  
Artery Disease

Background and objectives: Noninvasive assessment of coronary artery disease severity remains a clinical challenge. Myocardium subtended by obstructive coronary artery disease may show reduced left ventricular strain. The present study was intended to investigate whether this reduction of strain value correlates with increasing severity of coronary artery disease in Non-ST-Elevation Myocardial Infarction (NSTEMI) patients. Methods: This cross sectional study included 86 patients of NSTEMI. We assessed myocardial strain in global longitudinal strain (GLS) value using two dimensional speckle tracking echocardiography (2DSE). We performed coronary angiogram of the same patients and documented presence or absence of significant disease, number of affected vessels and Gensini score. Significant coronary artery was defined as ≥70% stenosis in any major coronary artery and or ≥50% stenosis in left main coronary artery. Results: Global longitudinal strain value was significantly lower in the significant coronary artery disease group (-13.5±3.4% vs. -19.01±2.3%) (p < 0.001). GLS declined proportionately with increasing severity of coronary artery disease defined by number of affected vessels (p < 0.001). Spearman’s rank correlation coefficient test between GLS value and Gensini score showed that the two variables maintained a linear but inverse relationship (ρ = 0.816, p < 0.001) that implies decreasing GLS is associated with increasing Gensini score. Multivariate logistic regression analysis found global longitudinal strain as an independent predictor of coronary artery disease. Conclusion: Myocardial strain assessed in global longitudinal strain value correlates with angiographic severity of coronary artery disease in patients with Non-ST-Elevation Myocardial Infarction.

Sign in / Sign up

Export Citation Format

Share Document