scholarly journals PAP-Smear Study and its Utility in Cervical Cancer Screening in a Tertiary Care Hospital in Chittagong, Bangladesh

2014 ◽  
Vol 13 (1) ◽  
pp. 17-19 ◽  
Author(s):  
Sabina Yeasmin ◽  
Tahera Begum ◽  
Lutfun Naher Begum ◽  
A.S.M. Mostaque Ahmed ◽  
Babul Osman

Background & Purpose: In developing countries, cervical cancer is the most common gynecological cancer and one of the leading causes of cancer death. Cervical cancers can be prevented through early detection and cervical smear is a sensitive test for it.Materials & Methods: This retrospective study was carried out at Chattagram Maa- Shishu O General Hospital, between July 2012 and June 2013. Total 500 patients were screened having complaints of vaginal discharge, irregular bleeding per vagina, post coital bleeding or something coming out per vagina. History and symptoms along with parity were recorded. Smears were taken by trained Doctor using modified Ayres wooden spatula and plastic endocervical cytobrush which were inserted and rotated 360 over cervix. Both ectocervix and endocervix were sampled. Slides were prepared, labeled, fixed in 95% ethyl alcohol immediately and subsequently stained by pap stain. After staining, slides were mounted with DPX (distren dibutyl phthalate xylene), screened and reported by two Cytopathologist according to The 2001 Bethesda system.Results: Age ranged from 20 to 50 and 50 to75 years with an average age of 37 years. Four hundred sixty five (93%) cases showed inflammatory lesions, 15 (3%) showed atrophy, 8 (1.6%) showed metaplasia and others showed ASCUS, AGUS, LSIL, HSIL, SCC. Eighty percent of all the epithelial abnormalities were found in the age group of 40 years and above. Average age of patients for all the epithelial abnormalities was 49 years.Conclusion: Cervical cancer is one of the most common malignancies in the women of Bangladesh. Pap smear cytology is a useful screening tool to detect pre-invasive cervical epithelial lesions. Based on the findings of this study we recommend at least a single life-time Pap screening cytology of the uterine cervix of all the women aged 40 to 50 years.DOI: http://dx.doi.org/10.3329/cmoshmcj.v13i1.19412

Author(s):  
Paridhi Garg ◽  
Shweta Mishra ◽  
Pragati Divedi

Background: Cervical cancer is one of the major causes of mortality among women worldwide. By simple pap screening test cervical cancer and its precursor lesions can be detected and treated early. The aim of the study was to determine and analyze Pap smear reports from women presenting with various gynaecological indications in a tertiary care hospital.Methods: This retrospective study was conducted in the department of obstetrics and gynaecology at Rama Medical College Hospital and Research Centre, Hapur over a period of 6 months. Patients with various complaints between ages 21 to 70 years were screened during August 2020 to January 2021 by taking Pap smear using Ayres spatula. Total 330 patients were studied.  Slides were reported according to the 2014 Bethesda system.Results: Maximum number of cases were in the age group 31-40 years constituting 32.72% of the total cases followed by age group 41-50 years. Vaginal discharge was the commonest chief complaint seen in 32.12% cases followed by menorrhagia. Maximum number of cases reported as non-specific inflammatory smears (64.54%). Among epithelial cell abnormalities incidence of LSIL was 2.42% followed by ASCUS (1.82%).Conclusions: Pap smear testing is an economical, non-invasive and simple OPD procedure to detect potentially precancerous and cancerous lesions of cervix. It should be established as a routine screening procedure to reduce the treatment burden, morbidity and mortality.


2020 ◽  
Vol 11 (SPL2) ◽  
pp. 92-96
Author(s):  
Varsha Reddy N ◽  
Yogesh Mohan ◽  
Charumathi B ◽  
Timsi Jain

In recent years cervical cancer has been witnessed as the second most prevalent cancer amongst females throughout the world. Sadly, regardless of the proof of methods for prevention, the majority of the females endure unscreened. The hurdles to screening include ignorance towards risk factors, manifestations, stigma, and fallacy about gynecological ailments. This research was conducted with the objective to describe the extent of awareness about cervical carcinoma and its screening among patient’s attenders who are women and are in the reproductive age group in a tertiary hospital. A cross-sectional study was conducted among patient's attenders age 15-45 years at a tertiary health care center, i.e., Saveetha Medical College and Hospital (SMCH) with a sample size of 158 and purposive sampling technique was used. Data was gathered using a semi-structured questionnaire. Data were entered in Microsoft Excel and analyzed using relevant statistical tests. Out of 158 study participants at SMCH,85 (53.7%) of them have heard about cervical cancer, 88 (55.6%) are apprised of screening of cervical carcinoma and 40 (25.3%) of them have been screened for cervical carcinoma using Pap smear. Study shows that more than half of the women have a satisfactory extent of awareness regarding cervical carcinoma. However, uptake of screening services is low. These results indicate that we need to increase awareness about cervical cancer and its screening.


Author(s):  
Ruksana Farooq ◽  
Azhar-un-Nisa Quraishi ◽  
Shahida Mohammad

Background: Cervical cancer is the most common genital cancer in India. In India alone,almost,130000 new cases occur with the death toll of 70000 everywhere. Objective of current study was correlation of pap smear with histopathological diagnosis.Methods: A retrospective study was conducted in tertiary care hospital in 130 sexually active women. Pap smears were taken and histopathological diagnosis was performed in all such patientsResults: From pap smear findings, out of 130 patients, maximum number of cases, 74 (56.9%) were categorized as. Out of epithelial cell abnormality, ASCUS was seen in 25 patients (10.2%), LSIL in 17 patients (13.1%), HSIL in 11 patients (8.5%). SCC was seen in 2 patients (1.5%) and adenocarcinoma in 1 patient (0.8%). From cervical biopsy reports, 51 cases(39.2%) were diagnosed as chronic cervicitis, 34 cases (26.2%) were diagnosed as chronic cervicitis with squamous metaplasia, CIN I in 31 patients (23.8%), CIN II in 8 patients (6.2%) and CIN III in 3 patients (2.3%), squamous cell carcinoma in 2 patients (1.5%) and adenocarcinoma in 1 patient (0.8%). The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of pap smear test was 91.1%, 82.4%,73.2%, 94.6% and 85.4%, respectively.Conclusions: Pap smear has excellent correlation with histopathological diagnosis. Therefore it should be encouraged as effective tool for cervical cancer screening program to reduce incidence and mortality caused by cervical cancer. 


2021 ◽  
Vol 12 (8) ◽  
pp. 144-148
Author(s):  
Anil Kumar Sirasagi ◽  
Arpitha K ◽  
Saara Neha ◽  
Pratima Manohar Pattar

Background: Cervical cancer in women is the second most common cancer and the commonest cause of mortality in developing countries. The introduction of Pap smear test changed the scenario of cervical cancer with an intense drop in the incidence and mortality due to invasive cervical cancer. Aims and Objective: To evaluate the patterns of cervical smear cytology and to correlate the cervical smear diagnosis with histopathological diagnosis and to assess the efficacy of Pap smears in diagnosing cervical lesions. Materials and Methods: This two-year retrospective study (January 2018 to December 2019) was done in the department of Pathology in a tertiary care hospital. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy were calculated considering histopathological diagnosis of cervical biopsy as the gold standard. Results: A total of 316 Pap smears were studied, out of which we selected 154 cases who also undergone biopsy or hysterectomy. Epithelial cell abnormalities (ECA) were found in 28 cases (18.2%). Among this the most common ECA was Atypical squamous cells of undetermined significance (ASCUS) seen in 10 cases (6.5%) followed by LSIL (5.2%), HSIL (3.2%) and SCC of cervix (3.2%). The overall correlation between cervical cytology and histopathology was found in 125 out of 154 cases (81.16%). The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of pap smear was 90.57%, 62.50%, 95.41%, 43.47% and 87.66% respectively. Conclusion: Pap smear is a simple, safe, non-invasive and effective method for detection of lesions of the cervix and ECA. Hence, better awareness and periodical cytological screening programs can help in the early detection of malignant cervical lesions and thereby reducing the morbidity and mortality related to this malignancy.


Author(s):  
Bhabani Pegu ◽  
Niharika Dhiman ◽  
Jaya Chaturvedi ◽  
Suresh K. Sharma

Background: Cervical cancer is one of the commonest cancers among women which cause morbidity and mortality worldwide. Though, it is a preventable disease, most of the women with cervical cancer present in advanced stage due to lack of knowledge about the disease and screening among general population. The objective was to assess the level of knowledge and explore attitude towards cervical cancer screening among female nursing staff.Methods: A cross sectional, questionnaire based study was conducted on 34 female nursing staff in a tertiary care hospital of Uttarakhand, India in the month of January 2015. With the help of predesigned questionnaire, information was collected regarding demographic profile, knowledge about cervical cancer and attitude towards screening techniques.Results: In this study, 79% of the respondents had knowledge about screening methods for cervical cancer and 91% had knowledge about HPV vaccine. Though 82% of them were aware of pap smear and 89% had good attitude towards it, 85.29% respondent knew about colposcopy as one of the screening technique for cervical cancer. None of the respondent had undergone a pap smear themselves.Conclusions: The study showed that, female nursing staff had average knowledge and positive attitude towards cervical cancer screening. They were not aware of the routine screening guidelines and had limited understanding of different types of cervical cancer screening techniques. Hence, it is recommended that routine training should be given on regular basis to all the health care providers.


2018 ◽  
Vol 17 (2) ◽  
pp. 12-18
Author(s):  
Meenu Maharjan ◽  
Heera Tuladhar

Introduction: Cervical cancer is the leading cause of cancer deaths for women worldwide. Early diagnosis of cervical cancer may be done by a simple and cost effective technique of Pap smear. The morbidity and mortality could be significantly reduced with an active cervical cancer screening programme.Methods: A cross sectional interview based study was done among 200 patients attending Obstetrics and Gynaecology OPD of one of the tertiary care hospital at Lalitpur, to assess the knowledge and awareness of patient regarding screening methods of cervical cancer and its prevention and early detection. Results: Among all the participants, 76.5% (n-153) were literate and 23.5% (n-47) were illiterate. Only 41% had heard about the Pap test and only 1% had heard about other methods of screening test like VIA(Visual Inspection with Acetic acid). Only 16% think that infection of the genital tract and 12.5% think that multiple partners is the leading cause of cervical cancer. Among them 51% (n-102) think that regular screening will prevent cervical cancer. But only 22.5% (45) had done Pap smear once and 67% did not know the risk factor of cervical cancer.  Only 7% had heard of HPV vaccination but did not know  details about it.Conclusions: There is very low level of knowledge about cervical cancer, Pap smear and HPV among the participants attending Obstetrics and Gynaecology OPD. For using Pap smear as a preventive method for cervical cancer, it is necessary to inform women about cervical cancer and the Pap smear test. An aggressive campaign with in depth teaching about cervical cancer by media and health care providers is mandatory. 


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