scholarly journals An Unusually Big Cervical Fibroid Polyp : A Case Report

2017 ◽  
Vol 15 (2) ◽  
pp. 65-67
Author(s):  
Shireen Akhter Khanam ◽  
Fahmida Rashid ◽  
Shahanara Chowdhury
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Connective Tissue ◽  
Smooth Muscle Cells ◽  
Solid Tumor ◽  
Vaginal Hysterectomy ◽  
Good Condition ◽  
The Body ◽  
Fibrous Connective Tissue ◽  
Fibroid Polyp

Fibroid Uterus is the most common benign solid tumor in female. Most of fibroids situated in the body of the uterus, cervical myoma account 3% -8% of uterine myoma. Cervical myoma are uncommon in different presentation, resembling inversion of uterus, malignancy & various sizes are reported in literature. A case of big cervical fibroid polyp has been reported here. Patient presented something coming down per vagina with foul smelling discharge. On examinations there was a hugely enlarged, infected mass about 15cm x 12cm which was arising from posterior lip of the cervix & outside the introitus. As the patient was 45 years & had menorrhagia, Non Descend Vaginal Hysterectomy (NDVH) was done without resecting the polyp priorly. Patient was discharged in good condition. Histopathology confirmed the diagnosis and reported leiomyoma with areas of degeneration which was mainly composed of involuntary smooth muscle cells & fibrous connective tissue from cervix which probably expelled out as a polyp attached to posterior lip of cervix.Chatt Maa Shi Hosp Med Coll J; Vol.15 (2); Jul 2016; Page 65-67

scholarly journals Effects of Herbal formulations in management of Uterine Fibroid (Sul’ah-E-Rehm) – A Case Report

2021 ◽  
Vol 5 (2) ◽  
pp. 91-97
Author(s):  
Mohammad Shamim Khan ◽  
Shaikh Imran ◽  
Mobashshera Khan
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Connective Tissue ◽  
Oral Administration ◽  
Uterine Fibroid ◽  
Uterine Fibroids ◽  
Fibrous Connective Tissue ◽  
Indian Women ◽  
Reproductive Life ◽  
Herbal Formulations

Uterine fibroid is the commonest benign and solid tumor in female during reproductive life. Approximately 15-25 million of Indian women have affected from fibroid uterus. Histologically itis composed of smooth muscle and fibrous connective tissue of varying proportional. It is considered as Sul’ah (tumor) in Unani classic litretures, as Ali Ibn-e-Abbas Majusi (930-994 AD) defined it under the topic of Warm-e-Balghami; as it is a swelling filled with viscid phlegm (Balgham-e-Ghaleez).Present paper deals with a reports of a 30 years old female having uterine fibroids measuring 2.6 cm× 3.1 cm, 2.6 cm× 3.6 cm, with left ovarian cyst of 3.1 cm × 4 cm. Patient was treated with herbal formulations; Majun Dabeedul Ward ( 5 gm paste), Kanchanar Guggul (2 tablet) and Niswani (10 ml syrup) twice a day for 8 consecutive weeks as oral administration. The patient was clinically assessed fortnightly, and radiologically just after treatment. Patient has shown encouraging result in post treatment investigation of Ultrasonography and finally patients got free from uterine fibroids without operation. The drugs were found to be safe and effective in this case.

scholarly journals Immunocytochemical characteristics of submucosal uterine myomas

2010 ◽  
Vol 67 (12) ◽  
pp. 977-982 ◽  
Author(s):  
Aleksandra Mladenovic-Mihailovic ◽  
Zorica Mladenovic-Bogdanovic ◽  
Predrag Mitrovic ◽  
Irena Tanaskovic ◽  
Slavica Usaj-Knezevic ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Connective Tissue ◽  
Smooth Muscle Cells ◽  
Smooth Muscle Actin ◽  
Muscle Cells ◽  
Synthetic Activity ◽  
Benign Tumors ◽  
Paraffin Sections ◽  
Weak Reaction ◽  
Synthetic Phenotype

Background/Aim. Myomas of the uterus, the most common benign tumors, have been studied for decades from the aspects of different basic and clinical disciplines. Despite this fact, their pathogenesis is still poorly understood. The aim of this study was to determine immunocytochemical characteristics of smooth muscle cells and connective tissue components of submucosal myomas of the uterus. Method. During the course of this study, 25 samples of submucosal myomas of the uterus were analyzed, all of them obtained during the surgery, after abdominal histerctomy by Aldridge. The samples were fixed in 4% formalin and embedded in paraffin. Sections of 5 ?m thickness were stained immunocytochemically using the DAKO LSAB+/HRP technique to identify ?- smooth muscle actin (?-SMA), vimentin, desmin, CD34, CD45, CD68 and PCNA (DAKO specification). Results. Our results suggest that submucosal myomas of the uterus are build-up of smooth muscle cells which are immunoreactive to ?-SMA and desmin, but also to a certain number of smooth muscle cells which are immunoreactive to ?-SMA and vimentin. Some of vimentin-immunoreactive cells also show an immunoreactivity of PCNA. In the build-up of connective stroma CD34-immunoreactive fibroblasts and neovascular formations are also present. By examining the distribution of CD45 antigen, at all the analyzed samples we observed a weak reaction. Conclusion. Submucosal myomas of the uterus are made-up of smooth muscle cells of the highly differentiated contractile phenotype (?-SMA- and desminimmunoreactivity), as well as smooth muscle cell of the synthetic phenotype which proliferate (?-SMA-, vimentin- and PCNA-immunoreactivity). In submucosal myoma of the uterus there is a significant presence of connective tissue as a result of synthetic activity of fibroblasts, which clearly differ in their immunocytochemical characteristics from smooth muscle cells of the synthetic phenotype.

Lymphangioma of the Pancreas With “Ovarian-like” Mesenchymal Stroma: A Case Report With Emphasis on Histogenesis

2003 ◽  
Vol 127 (11) ◽  
pp. 1513-1516 ◽  
Author(s):  
Lizhen Gui ◽  
Steven A. Bigler ◽  
Charu Subramony
Keyword(s):  
Endothelial Cells ◽  
Smooth Muscle ◽  
Case Report ◽  
Smooth Muscle Cells ◽  
Muscle Cells ◽  
Mesenchymal Cells ◽  
Developmental Anomaly ◽  
Mesenchymal Stroma ◽  
Multiple Cysts ◽  
Lymphoid Aggregates

Abstract Pancreatic lymphangiomas, which occur predominantly in women, are rare and account for only 1% of all lymphangiomas. The characteristic histologic features include multiple cysts lined by endothelial cells, irregularly distributed smooth muscle cells, and lymphoid aggregates in the wall of the cyst. We describe a 36-year-old woman with lymphangioma of the pancreas with “ovarian-like” mesenchymal stroma in the wall. This stroma, composed of uncommitted mesenchymal cells, has not been described previously in the wall of pancreatic lymphangiomas. Multiple small lymphatic channels that are found in this stroma recapitulate the development of lymphatic channels in the embryo. Lymphangioma of the pancreas may arise from distension of these lymphatic channels. Pancreatic lymphangioma may, therefore, be a developmental anomaly rather than a true neoplasm.

Exuberant Smooth Muscle Cells in Fibroadenoma of the Breast - A Case Report -

2010 ◽  
Vol 44 (4) ◽  
pp. 431
Author(s):  
Ga-Eon Kim ◽  
Young Kim ◽  
Eun-Hui Jeong ◽  
Jo-Heon Kim ◽  
Min-Ho Park ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Smooth Muscle Cells ◽  
Muscle Cells

The Role of Endothelial Cell Injury and Platelet Response in Atherogenesis

1977 ◽  
Author(s):  
L. A. Harker ◽  
R. Ross ◽  
J. Glomset
Keyword(s):  
Smooth Muscle ◽  
Endothelial Cell ◽  
Connective Tissue ◽  
Smooth Muscle Cells ◽  
Lipid Accumulation ◽  
Blood Platelets ◽  
Muscle Cells ◽  
Endothelial Injury ◽  
Intimal Proliferation ◽  
Flowing Blood

Endothelium forms a resistant barrier between flowing blood and vessel wall structures. Endothelial thromboresistance is maintained in part by the synthesis of prostacyclin, a potent prostaglandin inhibitor of platelet function. Loss of endothelial cells, mediated by physical, chemical, infectious or immune mechanisms, exposes the sub endothelium to flowing blood. Platelets react to the subendothelial connective tissue structures, undergoing adhesion and release of intracellular constituents, including a factor that is mitogenic to smooth muscle cells. This growth factor is a heat stable, basic protein (IP 7.4–9.4) of 20,000 Daltons and appears to be responsible for the intimal proliferation of smooth muscle cells that follows endothelial cell desquamation. After a single injury event the intimal lesion regresses over several months. Repeated or continuous endothelial cell loss results in progressive intimal proliferation of smooth muscle cells, their secretion of connective tissue matrix components (collagen, elastin and proteoglycans) and accumulation of lipid when animals are on a hypercholesterolemic diet to form early atherosclerotic intimal lesions. Discontinuance of endothelial injury and restoration of the endothelium appear to be followed by lesion regression except when lipid accumulation is extensive. Possible approaches to atherosclerosis prevention include: 1) protection of the endothelium by interruption or avoidance of endothelial injury factors, and perhaps by pharmacologic protection; 2) inhibition of platelet reactivity; 3) modification of SMC proliferation, secretion or lipid accumulation.

scholarly journals Acquired smooth muscle hamartoma: A case report on the lower extremity with hidrosis

2019 ◽  
Vol 7 ◽  
pp. 2050313X1989383
Author(s):  
Malika A Ladha ◽  
Todd Remington
Keyword(s):  
Smooth Muscle ◽  
Case Report ◽  
Lower Extremity ◽  
Smooth Muscle Cells ◽  
English Literature ◽  
Surgical Excision ◽  
Muscle Cells ◽  
Clinical Spectrum ◽  
Rare Entity ◽  
First Case

Smooth muscle hamartomas are benign dermal proliferations of smooth muscle cells. Smooth muscle hamartomas are sub-divided into congenital or acquired; the latter is a rare entity with less than 20 cases being reported in the English literature. Most often asymptomatic, acquired smooth muscle hamartomas follow an indolent course. Treatment in the form of surgical excision can be utilized for symptomatic or cosmetic purposes. Here, we report the first case of an acquired smooth muscle hamartomas of the shin which also uniquely presented with hidrosis. This case highlights the varied clinical spectrum of acquired smooth muscle hamartomas.

scholarly journals Ossifying chondrolipoma of the tongue

2012 ◽  
Vol 69 (11) ◽  
pp. 1009-1012 ◽  
Author(s):  
Desanka Tasic ◽  
Milorad Pavlovic ◽  
Dragan Stankovic ◽  
Irena Dimov ◽  
Goran Stanojevic ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Connective Tissue ◽  
Dorsal Surface ◽  
Osseous Metaplasia ◽  
Fibrous Connective Tissue ◽  
Lamellar Bone ◽  
Cartilaginous Tissue ◽  
Unusual Lesion ◽  
Lipomatous Tumors

Introduction. Chondrolipomas and osteolipomas are uncommon variants of lipomatous tumors. Case report. We presented a 60-year-old woman with ossifying chondrolipoma of the tongue. Clinical examination revealed a firm nodular mass, located in the midline of the posterior region on the dorsal surface of the tongue. Histologically, the lesion was well-delimited showing areas of mature adipocytes arranged in lobules and separated by fibrous connective tissue septa, islands of mature cartilaginous tissue and osseous metaplasia. Trabeculae of lamellar bone within a fibro-fatty background were visible throughout the tumor. The cartilaginous areas merging centrally with bone formation and fatty marrow tissue were present, as well as the hematopoietic elements in the fatty marrow. The bone forming was found to be through both membranous and enchondral mechanisms. Conclusion. Ossifying chrondrolipoma with hematopoietic elements is extremely unusual lesion. This interesting entity should be kept in mind in the differential diagnosis of lingual lesions.

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