scholarly journals Prevalence of hypokalemia in COVID-19 and its association with clinical and common laboratory parameters

2021 ◽  
Vol 29 (2) ◽  
pp. 131-137
Author(s):  
Md Khairul Islam ◽  
Pratyay Hasan ◽  
Md Murad Hossain ◽  
Fahima Sharmin Hossain ◽  
Tazdin Delwar Khan ◽  
...  
Keyword(s):  
Plasma Potassium ◽  
Shortness Of Breath ◽  
College Hospital ◽  
Cross Sectional ◽  
Angiotensin System ◽  
Laboratory Parameters ◽  
Medical College ◽  
Appropriate Treatment ◽  
The Mean ◽  
Common Laboratory

Importance: Hypokalemia is a neglected common manifestation in COVID-19 patients admitted in hospital though it has serious consequences. Coronavirus may cause hypokalemia through disruptions of rennin-angiotensin system, gastrointestinal loss or other unknown mechanisms. Objective: To investigate the prevalence of hypokalemia among patients with moderate to severe COVID-19 and its association with other clinical and laboratory parameters. Design, Setting, and Participants: This was cross sectional observational study conducted at Dhaka medical College Hospital of Bangladesh from June, 2020, to August 2020. Participants were included who were positive for rt-PCR for COVID-19 according to the national guideline. The patients were classified as having severe hypokalemia (plasma potassium <3 mmol/L), hypokalemia (plasma potassium 3-3.5 mmol/L), and normokalemia (plasma potassium >3.5 mmol/L). Results: Prevalence of hypokalemia among patients with COVID-19 was 20.2%, severe hypokalemia (2 patients [1.5%]) and hypokalemia (25 patients [18.7%]). One thirty four (134) patients with positive COVID-19 were included. The mean [SD] age of these 134 patients according to different potassium levels appear to be : 68 [2.83] years for severe hypokalemia , 51.93[11.68] years for hypokalemia and 50.73[14.7] years for normokalemia. Among them, 46 patients were females [34.32%]) and rest were males [65.68%]. Within the total sum of 134 patients, 107 were identified having normokalemia, [79.9%]. 25 patients [18. 7%] had hypokalemia and only two patients [1.5%] were found having normokalemia. Among 134 patients, three commonest symptoms were fever (132 patients [98.5%]), dry cough (123 patients (91.79%) and shortness of breath (122 patients [91.04%]), followed by less common symptoms like fatigue (89 patients [66.410%]), sore throat (60 patients [44.77%]), and diarrhea (44 patients, [32.83%]). Shortness of breath was associated with grades of hypokalemia (P=0.022). Only 26 patients (19.4%) manifested having vomiting/Nausea. The predominant comorbidities found among these 134 participants were Hypertension (68 patients [64.2%]), Diabetes (54 patients [52.9%]), Ischemic heart disease (37 patients [38.1%]) and Asthma (27 patients [31.0%]). The prevalence of comorbidities was not associated with Hypokalemia. Conclusions Prevalence of hypokalemia among patients with COVID-19 is high (20.2%) and appropriate treatment is highly required. J Dhaka Medical College, Vol. 29, No.2, October, 2020, Page 131-137

scholarly journals Haematocrit Value in Preeclampsia

2016 ◽  
Vol 30 (2) ◽  
pp. 80-85 ◽  
Author(s):  
Sankar Kumar Basak ◽  
Kohinoor Begum ◽  
Maliha Rashid ◽  
Nahid Yasmin ◽  
Hasina Begum
Keyword(s):  
Pregnant Women ◽  
Strong Association ◽  
Cross Sectional Study ◽  
P Value ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Group A ◽  
The Mean ◽  
Group B

Objective(s): To assess the association between the haematocrit value and severity of preeclampsia.Materials & Methods: This cross sectional study was conducted in the department of Obstetrics & Gynaecology of Dhaka Medical College Hospital, Dhaka during the period of January 2012 to December 2013. Total of 100 patients were studied and they were divided into two groups – group-A and group-B. Fifty preeclamptic patients were included in the group-A and 50 normal pregnant women were included in the group-B.Results: Majority of preeclamptic women (68%) and normal pregnant women (76%) were in the age group of 20-30 years with the mean ages of group-A and group-B subjects were 26.50±5.71 and 26.26±4.91 years respectively. Eighty six percent of group-A and 70% of group-B women were of lower socioeconomic status. Majority of the study subjects (74% of group-A and 80% of group-B) were housewife. More than half (54%) of the preeclamptic women were primigravid and 60% of normal pregnant women were multigravid. Among the preeclamptic subjects 16 (32%) had mild hypertension (DBP<110mmHg) and 34 (68%) had severe hypertension (DBP ? 110 mmHg). Out of 50 preeclamptic subjects 45 (90%) had severe proteinuria (+++) and only 5 (10%) had moderate (++) proteinuria.The mean haematocrit value of preeclamptic patients was 34.881±3.03 and that of normal pregnant women was 31.94±1.2. It was statistically significant (P value 0.001). The mean haematocrit value of normal pregnant, mild and severe preeclamptic women were 31.94±1.2, 33.31±2.57 and 35.62±2.95 respectively. It was also statistically significant (P value 0.001).Conclusion: This study shows that haematocrit value of preeclamptic patients is significantly higher compared to that of the normal pregnant women (P<0.05). There is a strong association of increasead haematocrit and preeclampsia.Bangladesh J Obstet Gynaecol, 2015; Vol. 30(2) : 80-85

Change of Positional Blood Pressure and Indication of Ephedrine in Hypotension During Spinal Anesthesia for Cesarean Delivery

2013 ◽  
Vol 21 (Number 2) ◽  
pp. 18-23
Author(s):  
Md. A Matin ◽  
J Banu ◽  
K Sultana ◽  
S M Shahana
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Clinical Practice ◽  
Spinal Anesthesia ◽  
Cesarean Delivery ◽  
Lateral Position ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
The Mean

Hypotension during spinal anaesthesia for caesarean section remains a common scenario in clinical practice. Certain risk factors play a role in altering the incidence of hypotension. A cross sectional observational study was done on sixty patients undergone cesarean delivery spinal anesthesia in Holy Family Red Crescent Medical College Hospital to evaluate the correlation between pre-anesthetic change of positional blood pressure and predictive necessity of Ephedrine to mange per-operative hypotension. The mean age of the patients included in the study was 25.85 ± 4.24 years and weighted 63.60 ± 6.91 kg (Mean ± sco. The haemodynamic outcomes of the patients are summarized in Table-I as mean systolic blood pressure increased (118 ± 12.02 and 132 ± 14.11 mm of Hg) after change of position from baseline (supine position) to right lateral position. The positional blood pressure varied from 2 to 32 mm of Hg and was observed in 54 patients. But only 35 patients were hypotensive (58.33%) after spinal anesthesia among them only 28 patients required Ephedrine (46.6%). But there was no significant correlation was observed in patients needed Ephedrine who hypotension but not obvious with positional change of pre-anesthetic blood pressure.

scholarly journals Shorter Timed Urine Collection for Detecting Proteinuria in Pre Eclamptic Women

2016 ◽  
Vol 27 (1) ◽  
pp. 9-13
Author(s):  
Nusrat Ara Yousuf ◽  
M Anwar Hussain ◽  
Khadija Begum
Keyword(s):  
Cross Sectional Study ◽  
Urinary Albumin ◽  
Albumin Concentration ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Urine Albumin ◽  
The Mean ◽  
Medical University ◽  
Criteria For Selection

Objective: To assess urinary albumin excretion in pre-eclamptic women by shorter timed collection of urine from 12 hours night sample.Method: This cross sectional study was carried out in the Department of Obstetric and Gynaecology, Bangabandhu Sheikh Mujib Medical University, and Dhaka Medical College Hospital, during the period of November 2004 to February 2005. Among the admitted patient total 40 pregnant women with pre-eclampsia were taken with proper selection criteria. The criteria for selection were hypertension (140/90 mmHg or more) after 20th week of gestation and a bed side urine albumin test positive. Detailed medical and obstetric history was taken and thorough examination was done and all the informations were recorded in the pre-designed data collection sheet.Results: The mean± SD urinary albumin in 12 hour day, 12 hour night and 24 hour sample were 1.74+0.51 gm/L, 1.76+0.51 gm/L and1.75+0.54 gm/L respectively. Urinary albumin concentration in the 12 hour day & night samples agreed well with concentration of the 24 hour samples.Conclusion: From the result it could be concluded that albumin concentrations in the 12- hours day and 12-hours night collections were close to the concentrations of the 24-hour collection.Bangladesh J Obstet Gynaecol, 2012; Vol. 27(1) : 9-13

scholarly journals Awareness About Hazards of Blood Transfusion Among the Recipients in a Selected Hospital in Dhaka City

2009 ◽  
Vol 13 (Number 2) ◽  
pp. 19-24
Author(s):  
A Mazid ◽  
Md. S H Khan ◽  
AHM O Farooque ◽  
Md. H AHM O ◽  
A Rubyt
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
The Mean ◽  
Demographic Condition ◽  
Cross Matching ◽  
Blood Grouping

This cross sectional descriptive study was conducted in Holy Family Red Crescent Medical College Hospital from September 2007 to December 2007 among the admitted patients, who received blood at that time, to assess the extent of awareness about hazards of blood wansfitsion among the blood recipients to find out the knowledge about blood grouping, cross matching. screening. quality of blood. fitness of blood donors. hazards due to blood transfission and sods demographic condition of the blood recipients. A total of 202 blood recipients were selected purposively. of them 75 were male and 127 were female. The mean age of the respondents were 41.6 years. of them mean or of the male was 46.3 years and the mean age of ihe fronale was 39.3 years. More than 93% of the respondents had some !net of education and 6.9% were illiterate; 41.6% of the respondents were house wife. 31.2% were service holder. 8.9% were business man and only 2.5% were of lower hiconte group. About the type of blood examination needed before rmisfitsion. 82.2% were aware about blood gimping. 51.5% about cross matching, 6.4% about Rh typing, 5.4% about screening and 17.8% had no idea. Regarding blood transfusion related diseases. 80.2% were aware about hepatitis 13. 60.9% about AIDS. 32.7% about syphilis, 22.3% about malaria and 20.8% of the respondents were totally unaware shoal the transfission related diseases. About reaction due to blood smut fission, 174 (86.1%) hod some idea but 28 (13.9%) were totally unaware about say reaction. Of the respondents, 196 (97%) preferred blood front unpaid vohnumv donors. friends and relatives, and only six (3%9 preferred professional donors. Only 4.5% of the respondents had idea about screening of blood before transficsion.

Changes of Proinflammatory Biomarkers of COVID-19 Patients and Its Relationship with HRCT Percentage- A Multi-Center Study in Tertiary Hospitals of Sylhet

2021 ◽  
Vol 11 (Number 2) ◽  
pp. 13-18
Author(s):  
Talha KA ◽  
Patwary MI ◽  
Bari MZJ ◽  
Rahman AAMS ◽  
Alam ZHMN ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Medical College Hospital ◽  
High Resolution Computed Tomography ◽  
College Hospital ◽  
Cross Sectional ◽  
Neutrophil Lymphocyte Ratio ◽  
Medical College ◽  
The Mean ◽  
Multi Center Study ◽  
D Dimer

Background and objectives- COVID-19 is a coronavirus disease declared pandemic by WHO. The commonly checked proinflammatory biomarkers are Neutrophil-Lymphocyte ratio (NLR), C - reactive protein (CRP), D-Dimer and Ferritin. High-Resolution Computed Tomography (HRCT) of chest is an important tool to evaluate the diagnosis and prognosis of COVID-19. The objective of this study was to evaluate the relationship between the biomarkers and HRCT findings. Materials and method- This was a multi-center cross-sectional study done in Sylhet Women’s Medical College Hospital (SWMCH), Sylhet Shahid Shamsuddin Ahmed Hospital (SSSAH), Northeast Medical College Hospital (NMCH) and Mount Adora Hospital, Sylhet. Data were collected from electronic medical record (EMR). Relationship test were done by independent t-test and one-way-ANOVA test. Results- Among the total 481 participant, 312 (65%) were male and rest 169 (35%) were female. The average age of the COVID-19 positive group participants was 60.72 year and it was 60.79 year in the COVID-19 negative group. The mean difference of D-Dimer between COVID-19 positive and negative patients was significant (p=0.0063). The mean differences of NLR (p=0.0012) and CRP (p=0.005) were significant between died and survived patients. Conclusion- All four biomarkers were raised in the higher HRCT percentage involved groups. NLR and DDimer were significantly (p<0.001) higher in the higher HRCT percentage groups.

scholarly journals Acute Herbicide Poisoning: An Emerging Phenomenon in Himachal Pradesh, India

2019 ◽  
Vol 5 ◽  
pp. 1
Author(s):  
Sujeet Raina ◽  
Vivek Sood ◽  
Bikram Shah ◽  
Manoj Thakur ◽  
Rajesh Sharma ◽  
...  
Keyword(s):  
Clinical Manifestations ◽  
Cross Sectional Study ◽  
Himachal Pradesh ◽  
Rural Setting ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
The Mean ◽  
Clinical Records ◽  
Mild Toxicity

The clinical manifestations of acute herbicide self-poisoning have not been widely studied in India. The objective was to study the clinical profile of herbicide poisoning cases admitted in a medical college hospital located in a rural setting of Himachal Pradesh. The clinical records of all patients diagnosed with acute herbicide poisoning between January 1, 2017, and February 15, 2019, were analyzed retrospectively in this hospital-based cross-sectional study. During the study period, 20 patients were diagnosed with acute herbicide poisoning and are included in this study. There were 13 males. The mean age was 33.6 ± 13.3 years. The herbicides ingested included 2,4-D (45%), paraquat (20%), glyphosate (10%), pendimethalin (10%), atrazine (5%), butachlor (5%), and metribuzin (5%). 2,4-D is the commonest acute herbicide self-poisoning in this region. It was observed that poisoning with herbicides is usually of mild toxicity except paraquat, which is associated with high mortality.

scholarly journals Etiological Evaluation of Acute Confusional State in Elderly (≥60 Years) Patients

2021 ◽  
Vol 22 (1) ◽  
pp. 41-45
Author(s):  
Md Motlabur Rahman ◽  
Rakesh Panday ◽  
Kamal Uddin Sohel ◽  
Zuhayer Ahmed ◽  
Shahana Khanam ◽  
...  
Keyword(s):  
The Elderly ◽  
Cross Sectional Study ◽  
Uncontrolled Hypertension ◽  
Medical Conditions ◽  
Acute Confusional State ◽  
Confusional State ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
The Mean

Background: Acute confusional state or delirium is a frequent cause of hospital admission in the elderly. It is characterized by an acute fluctuating impairment of cognitive functions and inattention. Recognition and prompt treatment is crucial to decrease the morbidity and mortality of hospitalized elderly patients. Aim of this study was to evaluate the distribution of common medical conditions related to acute confusional state among elderly hospitalized Patients. Methods: This was a cross sectional study. We enrolled 380 patients from different medicine wards in Dhaka Medical College Hospital. We included patients with acute confusional state/delirium of less than 7 days duration. The enrolled patients fulfilled the diagnostic criteria of an acute confusional state. A predesigned checklist was used for data collection. Head injury was excluded by history and CT scan of brain. Patients with preexisting illnesses, such as dementia, psychiatric illnesses and recurrent seizures, and any case of poisoning was excluded. All findings were noted and recorded. A written informed consent was taken from the attendant and relatives. Result: Among 380 patients, most of confusional state developed after the age of 65 years and the mean age was 69 +/-7.6 years. Associated medical conditions were uncontrolled hypertension (63.2%), fever & infection (41.6%), uncontrolled DM (36.6%), CVD (28.4%), CKD & electrolytes abnormalities (10.5%), joint diseases & pain (13.7%). Most of the patients used plyphormacy (76.6%) out of which antihypertensive (60%) were common. The mean duration of presentation was 6.1+/-0.6 days, and among all patients about 63.7% were improved, 29.50% was in persistant symptom of confusion and 6.8% of them died. Conclusion: Acute confusional state was common after 65 years. Uncontrolled hypertension, fever & infection, uncontrolled diabetes, CVD, CKD & electrolytes abnormalities and polypharmacy were found commonly in patients with acute confusional state. J MEDICINE JAN 2021; 22 (1) : 41-45

Fetomaternal Outcome of Eclampsia

KYAMC Journal ◽  
2018 ◽  
Vol 9 (3) ◽  
pp. 120-124
Author(s):  
Fatema Begum ◽  
Bedoura Sharmin ◽  
Umme Hafsa Zakia ◽  
Farhana Dewan ◽  
SM Asaduzzaman
Keyword(s):  
Maternal Mortality ◽  
Neonatal Intensive Care ◽  
Test Statistics ◽  
College Hospital ◽  
Cross Sectional ◽  
Mortality And Morbidity ◽  
Medical College ◽  
Maternal Mortality And Morbidity ◽  
Risk Patients ◽  
The Mean

Background: Eclampsia is a leading cause of maternal mortality and morbidity and adverse neonatal outcome. Healthcare system must be enhance to improve fetomaternal outcome.Objective: To find out the proportion and fetomaternal outcome of eclampsia.Materials and Methods: A cross sectional descriptive study was conducted to assess the fetomaternal outcome of eclampsia. The study was carried out at the Eclampsia unit, Dhaka Medical College Hospital, Dhaka over aperiod of six months from 1st July 2008 to 31st December 2008. A total of 48 patients with diagnosis of antepartum and intrapartum eclampsia were consecutively taken in the study. The test statistics used to analyse the data were descriptive statistics.Results: About 7% of patients developed acute renal failure,16.7% CVA,14.6% HELLP syndrome and 39.6% pulmonary oedema. The mean hospital stay was 9.5 ± 3.3 days. Majority (93.8%) of the patients recovered while 6.3% died. Twenty-seven (54.2%) neonates had to be referred to neonatal intensive care unit for better management. Of them 24 recovered following resuscitation. The mean weight of baby was 2.2±0.3 kg.Conclusion: Eclampsia is still a major cause of maternal mortality and morbidity in Bangladesh. Monitoring of high-risk patients may reduce the complication rate.KYAMC Journal Vol. 9, No.-3, October 2018, Page 120-124

Epidemiology of Eclampsia in Bangladesh

KYAMC Journal ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 189-192
Author(s):  
Fatema Begum ◽  
Arshad Jahan ◽  
Sheuly Akter ◽  
Farhana Dewan ◽  
Sinthia Tabassum
Keyword(s):  
Test Statistics ◽  
College Hospital ◽  
Cross Sectional ◽  
Mortality And Morbidity ◽  
Medical College ◽  
Prenatal Consultation ◽  
Community Monitoring ◽  
Maternal Mortality And Morbidity ◽  
Risk Patients ◽  
The Mean

Background: The purpose of these study was to find out the risk of eclampsia in relation to several demographic and anthropometric factor and to find out a way to prevent eclampsia. Objective: To find out the epidemiology of eclampsia and to reduce maternal and neonatal mortality and morbidity due to eclampsia. Materials and Methods: A cross sectional descriptive study was conducted to assess the fetomaternal outcome of eclampsia. The study was carried out at the Eclampsia unit, Dhaka Medical College Hospital, Dhaka over a period of six months from 1st July 2008 to 31st December 2008. A total of 48 patients with diagnosis of antepartum and intrapartum eclampsia were consecutively taken in the study. The test statistics used to analyse the data were descriptive statistics. Results: About 39.6% of the patients was under the age of 20 years, 43. 7% patient was between the age of 20-25 years. By occupation 77.1% patient was housewife, 17.9% patient was Garments worker and 4.1% patient was day labour. By level of education about 56.3% patient was illiterate, 29.2% patient was of primary level. About 57% of patients remained unconscious. About 7% of patients developed acute renal failure,16.7% CVA,14.6% HELLP syndrome and 39.6% pulmonary oedema. The mean hospital stay was 9.5 ± 3.3 days. Majority (93.8%) of the patients recovered while 6.3% died. Conclusion: Eclampsia is still a major cause of maternal mortality and morbidity in Bangladesh. A qualitative and quantitative improvement in prenatal consultation should make it possible to reduce incidence of eclampsia in our community. Monitoring of high-risk patients may reduce the complication rate. KYAMC Journal Vol. 11, No.-4, January 2021, Page 189-192

scholarly journals Effect of Maternal Preeclampsia on the Weight of the Placenta

1970 ◽  
Vol 8 (2) ◽  
pp. 69-71 ◽  
Author(s):  
Segupta Kishwara ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Mahamuda Begum ◽  
Khandaker Abu Rayhan ◽  
Shamim Ara
Keyword(s):  
Normal Pregnancy ◽  
Placental Weight ◽  
Control Group ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Control Group Group

Context: Preeclampsia is a relatively common pregnancy disorder that is related to the placenta and causes variable maternal and foetal problems. Alterations in placental weight are evident in moderate to severe maternal preeclampsia. Study design: Cross-sectional descriptive type. Place and period of study: Department of Anatomy, Dhaka Medical College, Dhaka from August 2005 to June 2006. Materials & Methods: 60 human placentae from Bangladeshi women were collected from the Department of Obstetrics & Gynaecology of Dhaka Medical College Hospital and Mitford Hospital, Dhaka of which 30 from normal uncomplicated pregnancies (control group or group A) and another 30 from pregnancies complicated by preeclampsia (preeclampsia group or group B), where the patients were normotensive previously. Results: The mean weight of the placenta was 406.90±72.64 gm in control group (group A) and 311.50±74.09 gm in preeclampsia group (group B) respectively. The mean difference in weight between two groups was statistically significant (P< 0.001). Conclusion: Placental weight was found reduced in maternal preeclampsia in comparison to that of normal pregnancy. Key words: weight of placenta; preeclampsia. DOI: 10.3329/bja.v8i2.7019Bangladesh Journal of Anatomy July 2010, Vol. 8 No. 2 pp. 69-71

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