Changes of Proinflammatory Biomarkers of COVID-19 Patients and Its Relationship with HRCT Percentage- A Multi-Center Study in Tertiary Hospitals of Sylhet

2021 ◽  
Vol 11 (Number 2) ◽  
pp. 13-18
Author(s):  
Talha KA ◽  
Patwary MI ◽  
Bari MZJ ◽  
Rahman AAMS ◽  
Alam ZHMN ◽  
...  

Background and objectives- COVID-19 is a coronavirus disease declared pandemic by WHO. The commonly checked proinflammatory biomarkers are Neutrophil-Lymphocyte ratio (NLR), C - reactive protein (CRP), D-Dimer and Ferritin. High-Resolution Computed Tomography (HRCT) of chest is an important tool to evaluate the diagnosis and prognosis of COVID-19. The objective of this study was to evaluate the relationship between the biomarkers and HRCT findings. Materials and method- This was a multi-center cross-sectional study done in Sylhet Women’s Medical College Hospital (SWMCH), Sylhet Shahid Shamsuddin Ahmed Hospital (SSSAH), Northeast Medical College Hospital (NMCH) and Mount Adora Hospital, Sylhet. Data were collected from electronic medical record (EMR). Relationship test were done by independent t-test and one-way-ANOVA test. Results- Among the total 481 participant, 312 (65%) were male and rest 169 (35%) were female. The average age of the COVID-19 positive group participants was 60.72 year and it was 60.79 year in the COVID-19 negative group. The mean difference of D-Dimer between COVID-19 positive and negative patients was significant (p=0.0063). The mean differences of NLR (p=0.0012) and CRP (p=0.005) were significant between died and survived patients. Conclusion- All four biomarkers were raised in the higher HRCT percentage involved groups. NLR and DDimer were significantly (p<0.001) higher in the higher HRCT percentage groups.

2015 ◽  
Vol 12 (1) ◽  
pp. 2-6
Author(s):  
Wahida Begum ◽  
Ahmed Hossain ◽  
Waziha A Jahan ◽  
Mahbuba Shirin ◽  
M Abdullah Yusuf ◽  
...  

Background: CT-scan is useful for the detection of hepatic mass. Objective: The purpose of the present study was to see the predictive values of CT scan in the diagnosis of malignant hepatic mass. Methodology: This cross sectional study was carried out in the Department of Radiology and Imaging at Mymensingh Medical College Hospital (MMCH), Mymensingh, Banghabandhu Sheikh Mujib Medical University (BSMMU), Dhaka and Dhaka Medical College Hospital (DMCH), Dhaka during the period of 1st January 2006 to 31st December 2007. Patients admitted in the Department of Medicine and Department of Hepatobiliary of MMCH, BSMMU, and DMCH with the clinical diagnosis of fever, abdominal pain, anorexia, nausea/vomiting, loss of appetite, jaundice, weight loss and ascites were selected as study population. CT scan and histopathology were performed to all the patients. Result: A total number of 50 patients were recruited for this study.. The sensitivity for multiplicity was 71.4%, specificity was 63.6%, accuracy was 68%, PPV was 71.4% and NPV was 63.6%. The sensitivity for hypodensity as a sign of malignancy was 60.7%, specificity was 18.2%, accuracy was 42.0%, PPV was 48.6% and NPV was 26.7%. The sensitivity, specificity, PPV, NPV and accuracy of contrast enhancement were 100.0%, 22.7%, 62.2%, 100.0% and 66.0% respectively. Again the sensitivity, specificity, PPV, NPV and accuracy of detection of pressure effect on biliary apparatus by CT-scan were 100.0%, 22.7%, 62.2%, 100.0% and 66.0% respectively. Again the sensitivity, specificity, PPV, NPV and accuracy of detection of Lymphadenopathy by CT-scan were 35.7%, 95.5%, 90.9%, 53.8% and 62.0% respectively. The sensitivity, specificity, PPV, NPV and accuracy of detection of Portal vein invasion by CT-scan were 14.3%, 100.0%, 100.0%, 47.8% and 52.0% respectively. The sensitivity, specificity, PPV, NPV and accuracy of detection of hepatic vein invasion by CT-scan were 10.7%, 100.0%, 100.0%, 46.8% and 50.0% respectively. The sensitivity, specificity, PPV, NPV and accuracy of detection of inferior vena cava (IVC) invasion by CT-scan were 7.1%, 100.0%, 100.0%, 45.8% and 48.0% respectively. Conclusion: CT is a useful diagnostic tool for the detection of malignant hepatic masses.Journal of Science Foundation, 2014;12(1):2-6


1970 ◽  
Vol 22 (1) ◽  
pp. 12-14
Author(s):  
Rhea Homaira ◽  
Sabera Khatun ◽  
Fahmida Zabin

This cross sectional study was carried out on hundred patients of vesicovaginal fistula who were admitted and underwent surgical treatment in Dhaka Medical college Hospital (DMCH), Dhaka, during the period of January, 2001 to June, 2003. The aim of this study was to obtain the outcome of the different methods of repair of different types of vesicovaginal fistula. An in-depth interview was taken from patients by using an open ended questionnaire. Necessary information about the procedure applied, together with results of operation were recorded in the data sheet. The result of this study showed that the anatomical success in closure of fistula occurred in 94% cases. In 38% of cases the size of the fistula were small in size, in 49% cases location were at the Junction of bladder neck, 78% of cases experienced no postoperative complications. Route of operation were vaginal in 84% cases. Previous attempt of repair were in 62% cases whereas in 38% women had history of operation. Obstetric vesicovaginal fistula is a curable condition. The success rate has been increased over time. More complicated cases which have been failed in previous attempts of repair are being referred. Most of the unsuccessful repair were bad cases (2%). So more training and experience of surgeons for repair of fistulas, employing modified technique wherever applicable can improve the result. DOI: 10.3329/medtoday.v22i1.5598 Medicine Today Vol.22(1) 2010. 12-14


2016 ◽  
Vol 30 (2) ◽  
pp. 80-85 ◽  
Author(s):  
Sankar Kumar Basak ◽  
Kohinoor Begum ◽  
Maliha Rashid ◽  
Nahid Yasmin ◽  
Hasina Begum

Objective(s): To assess the association between the haematocrit value and severity of preeclampsia.Materials & Methods: This cross sectional study was conducted in the department of Obstetrics & Gynaecology of Dhaka Medical College Hospital, Dhaka during the period of January 2012 to December 2013. Total of 100 patients were studied and they were divided into two groups – group-A and group-B. Fifty preeclamptic patients were included in the group-A and 50 normal pregnant women were included in the group-B.Results: Majority of preeclamptic women (68%) and normal pregnant women (76%) were in the age group of 20-30 years with the mean ages of group-A and group-B subjects were 26.50±5.71 and 26.26±4.91 years respectively. Eighty six percent of group-A and 70% of group-B women were of lower socioeconomic status. Majority of the study subjects (74% of group-A and 80% of group-B) were housewife. More than half (54%) of the preeclamptic women were primigravid and 60% of normal pregnant women were multigravid. Among the preeclamptic subjects 16 (32%) had mild hypertension (DBP<110mmHg) and 34 (68%) had severe hypertension (DBP ? 110 mmHg). Out of 50 preeclamptic subjects 45 (90%) had severe proteinuria (+++) and only 5 (10%) had moderate (++) proteinuria.The mean haematocrit value of preeclamptic patients was 34.881±3.03 and that of normal pregnant women was 31.94±1.2. It was statistically significant (P value 0.001). The mean haematocrit value of normal pregnant, mild and severe preeclamptic women were 31.94±1.2, 33.31±2.57 and 35.62±2.95 respectively. It was also statistically significant (P value 0.001).Conclusion: This study shows that haematocrit value of preeclamptic patients is significantly higher compared to that of the normal pregnant women (P<0.05). There is a strong association of increasead haematocrit and preeclampsia.Bangladesh J Obstet Gynaecol, 2015; Vol. 30(2) : 80-85


Author(s):  
Jeevankumar U. Yadav ◽  
Deepmala J. Yadav

Background: Globally there has been increased medicalization of pregnancy due to advances in technology. Ultrasonography examination during pregnancy has become an integral part of antenatal care throughout the world with advanced health care services.Methods: The cross-sectional study was conducted in pregnant women attending the ANC clinic of Obstetric department of D. Y. Patil Medical College Hospital, Kolhapur, Maharashtra, India for routine check up to know the awareness about ultrasonography among them. The study included 290 pregnant women. All were explained the purpose of study and assured confidentiality. Data has been collected from willing participants using pre-tested questionnaire in June-August 2015.Results: The study shows literacy was 87.6%, pregnancy above 20 years age 98.97% and most of them unskilled (83.4%), majority of middle social class (89%). Many (72.41%) pregnant women considered USG use to detect fetal anomalies while 27.93% considered for sex detection. Majority (93.1%) done USG in this pregnancy, of that more (43.45 %) in second trimester and mainly advised by doctors (91.03%). Nearly half of them (50.69%) considered its expensive procedure, 69.31% spent 200/- to 500/- rupees per USG, in spite 94.83% of them would recommend other pregnant women to undergo USG in pregnancy. 50.69%% of them opined it should be done twice in pregnancy. Almost 94.83% considered USG as safe and beneficial.Conclusions: Awareness regarding the uses of Ultrasonography during pregnancy and attitude towards it was found to be average. There is need to create more awareness in community about PCPNT act and its provisions. Also there is need of counselling about the safety, utility and frequency of USG during pregnancy to avoid misuse.


2016 ◽  
Vol 10 (1) ◽  
pp. 17-19
Author(s):  
Krishna Gopal Sen ◽  
Ahammed Ali ◽  
Md Kamal Mostofa ◽  
Sumitendra Kumar Sarkar ◽  
Chandona Sorcar ◽  
...  

The burden of scabies is highest in tropical countries, but recent data from Bangladesh is scanty. This cross sectional study was carried out to find the prevalence of scabies in skin & VD Out Patient Department (OPD) of Faridpur Medical College Hospital (FMCH) during the period of April 2013 to March 2014. Total 22,399 patients attended to the skin & VD OPD, were included in this study. We identified 15,455 patents with scabies. The total prevalence was 69%. Prevalence in January was highest & was 78%. Most cases were uncomplicated but 17.28% of complicated scabies patients were found. Scabies was more in poor socio-economic group than others. The present study showed a high prevalence of scabies in patients presenting to skin & VD OPD, FMCH. Prevalence was higher overall in children. Our data show that scabies is common in patients presenting to skin & VD OPD & this finding may be used as an indicator of the general population.Faridpur Med. Coll. J. Jan 2015;10(1): 17-19


2014 ◽  
Vol 26 (1) ◽  
pp. 46-48
Author(s):  
Devendra Nath Sarkar ◽  
Md Ismail Hossain ◽  
Mainuddinin Ahmed ◽  
AKM Shaheduzzaman ◽  
Nur Mohammad

Organophosphorus compounds (OPC) poisoning is a major public health problem in low and middle income countries. The incidence varies from country to country depending on easy availability of poison, socio-economic condition and educational background of the people. This study aimed to determine the frequency, outcome and aetiological aspect of OPC poisoning patient admitted in Rangpur medical college hospital. It was a cross sectional study carried out in the department of Medicine, Rangpur medical college hospital from 1st December 2011 to 30th November, 2012. During the study period a total of 703 patients have been studied. The most of the patients were between the age of 18- 40 years (91.9%), male (51.6%), married (71.3%) and from rural areas (67.8%). People of different occupations were involved in OPC poisoning, house-wives were the maximum (33.6%) followed by farmers (31.7%). 92% cases were suicidal and 8% accidental. Familial disharmony was the prime cause (92.3%) of suicidal motive. 88% of the patients were survived and 5% died. OPC poisoning is an important health care problem in our country. Improved awareness, restricting availability and banning more toxic organophosphorus compounds will reduce the incidence of OPC poisoning. DOI: http://dx.doi.org/10.3329/medtoday.v26i1.21313 Medicine Today 2014 Vol.26(1): 46-48


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